Neurodegeneration-Associated Protein Fragments as Short-Lived Substrates of the N-End Rule Pathway von Brower, Christopher S., Piatkov, Konstantin I., Varshavsky, Alexander

Volltext

N-end rule pathway counteracts cell death by destroying proapoptotic protein fragments von Piatkov, Konstantin I, Brower, Christopher S, Varshavsky, Alexander

Volltext

Calpain-generated natural protein fragments as short-lived substrates of the N-end rule pathway von Piatkov, Konstantin I, Oh, Jang-Hyun, Liu, Yuan, Varshavsky, Alexander

Volltext

The Auto-Generated Fragment of the Usp1 Deubiquitylase Is a Physiological Substrate of the N-End Rule Pathway von Piatkov, Konstantin I., Colnaghi, Luca, Békés, Miklos, Varshavsky, Alexander, Huang, Tony T.

Volltext

Glutamine-Specific N-Terminal Amidase, a Component of the N-End Rule Pathway von Wang, Haiqing, Piatkov, Konstantin I., Brower, Christopher S., Varshavsky, Alexander

Volltext

Formyl-methionine as a degradation signal at the N-termini of bacterial proteins von Piatkov, Konstantin I, Vu, Tri T M, Hwang, Cheol-Sang, Varshavsky, Alexander

Volltext

Liat1, an arginyltransferase-binding protein whose evolution among primates involved changes in the numbers of its 10-residue repeats von Brower, Christopher S., Rosen, Connor E., Jones, Richard H., Wadas, Brandon C., Piatkov, Konstantin I., Varshavsky, Alexander

Volltext

Analyzing N-terminal Arginylation through the Use of Peptide Arrays and Degradation Assays von Wadas, Brandon, Piatkov, Konstantin I., Brower, Christopher S., Varshavsky, Alexander

Volltext

Downregulation of the Arg/N-degron Pathway Sensitizes Cancer Cells to Chemotherapy In Vivo von Leboeuf, Dominique, Abakumova, Tatiana, Prikazchikova, Tatiana, Rhym, Luke, Anderson, Daniel G., Zatsepin, Timofei S., Piatkov, Konstantin I.

Volltext

Beta-amyloid induces apoptosis of neuronal cells by inhibition of the Arg/N-end rule pathway proteolytic activity von Kechko, Olga I, Petrushanko, Irina Yu, Brower, Christopher S, Adzhubei, Alexei A, Moskalev, Alexey A, Piatkov, Konstantin I, Mitkevich, Vladimir A, Makarov, Alexander A

Volltext

Calpain-generated natural protein fragments as short-lived substrates of the N-end rule pathway von Piatkov, Konstantin I., Oh, Jang-Hyun, Liu, Yuan, Varshavsky, Alexander

Volltext

The N-end rule pathway counteracts cell death by destroying proapoptotic protein fragments von Piatkov, Konstantin I., Brower, Christopher S., Varshavsky, Alexander

Volltext

Abstract 1841: TAK-500 is a clinical stage immune-cell directed antibody drug conjugate (iADC) inducing STING activation in CCR2-expressing intratumor myeloid cells and favorable i... von Schalper, Kurt A., Matsuda, Atsushi, Ganno-Sherwood, Michelle, Maldonado-Lopez, Angel E., Rosentrater, Emily, Porciuncula, Angelo, Zhang, Dong Mei, Christensen, Camilla L., Merrigan, Samantha A., Hatten, Tiquella, Lee, Hong Myung, Lee, Min Young, Dong, Linlin, Huang, Jian, Iartchouk, Natasha, Wang, Jianing, Xu, He, Yoneyama, Tomoki, Piatkov, Konstantin I., Harbison, Carole E., Parent, Alex, Lineberry, Neil, Abu-Yousif, Adnan O., Appleman, Vicky

Volltext

Quantifying LAGA mutated mouse IgG2a monoclonal antibody with a rapid pepsin digestion enabled immunoaffinity LC/MS/MS assay von Dong, Linlin, Chen, Susan, Piatkov, Konstantin, Wei, Dong, Qian, Mark G

Volltext

Leveraging a physiologically-based quantitative translational modeling platform for designing B cell maturation antigen-targeting bispecific T cell engagers for treatment of multip... von Yoneyama, Tomoki, Kim, Mi-Sook, Piatkov, Konstantin, Wang, Haiqing, Zhu, Andy Z. X

Volltext

Substrate-binding Sites of UBR1, the Ubiquitin Ligase of the N-end Rule Pathway von Xia, Zanxian, Webster, Ailsa, Du, Fangyong, Piatkov, Konstantin, Ghislain, Michel, Varshavsky, Alexander

Volltext

Novel Apoptotic Mediators Identified by Conservation of Vertebrate Caspase Targets von Gubina, Nina, Leboeuf, Dominique, Piatkov, Konstantin, Pyatkov, Maxim

Volltext

An Automated Multicycle Immunoaffinity Enrichment Approach Developed for Sensitive Mouse IgG1 Antibody Drug Analysis in Mouse Plasma Using LC/MS/MS von Dong, Linlin, Bebrin, Nicole, Piatkov, Konstantin, Abdul-Hadi, Kojo, Iwasaki, Shinji, Qian, Mark G, Wei, Dong

Volltext

Abstract 3131: Ubiquitin ligases: a new target for RNAi therapy of hepatocellular carcinoma von Leboeuf, Dominique, Zatsepin, Timofei, Anderson, Daniel G., Piatkov, Konstantin

Volltext

Ubiquitin reference technique and its use in ubiquitin-lacking prokaryotes von Piatkov, Konstantin, Graciet, Emmanuelle, Varshavsky, Alexander

Volltext