Conformationally Constrained ortho-Anilino Diaryl Ureas: Discovery of 1‑(2-(1′-Neopentylspiro[indoline-3,4′-piperidine]-1-yl)phenyl)-3-(4-(trifluoromethoxy)phenyl)urea, a Potent, S... von Qiao, Jennifer X, Wang, Tammy C, Ruel, Réjean, Thibeault, Carl, L’Heureux, Alexandre, Schumacher, William A, Spronk, Steven A, Hiebert, Sheldon, Bouthillier, Gilles, Lloyd, John, Pi, Zulan, Schnur, Dora M, Abell, Lynn M, Hua, Ji, Price, Laura A, Liu, Eddie, Wu, Qimin, Steinbacher, Thomas E, Bostwick, Jeffrey S, Chang, Ming, Zheng, Joanna, Gao, Qi, Ma, Baoqing, McDonnell, Patricia A, Huang, Christine S, Rehfuss, Robert, Wexler, Ruth R, Lam, Patrick Y. S

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Potent non-nitrile dipeptidic dipeptidyl peptidase IV inhibitors von Simpkins, Ligaya M., Bolton, Scott, Pi, Zulan, Sutton, James C., Kwon, Chet, Zhao, Guohua, Magnin, David R., Augeri, David J., Gungor, Timur, Rotella, David P., Sun, Zhong, Liu, Yajun, Slusarchyk, William S., Marcinkeviciene, Jovita, Robertson, James G., Wang, Aiying, Robl, Jeffrey A., Atwal, Karnail S., Zahler, Robert L., Parker, Rex A., Kirby, Mark S., Hamann, Lawrence G.

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Identification of a Hydroxypyrimidinone Compound (21) as a Potent APJ Receptor Agonist for the Potential Treatment of Heart Failure von Meng, Wei, Pi, Zulan, Brigance, Robert, Rossi, Karen A, Schumacher, William A, Bostwick, Jeffrey S, Gargalovic, Peter S, Onorato, Joelle M, Luk, Chiuwa E, Generaux, Claudia N, Wang, Tao, Wexler, Ruth R, Finlay, Heather J

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Synthesis and SAR of 4-carboxy-2-azetidinone mechanism-based tryptase inhibitors von Sutton, James C, Bolton, Scott A, Hartl, Karen S, Huang, Ming-Hsing, Jacobs, Glenn, Meng, Wei, Ogletree, Martin L, Pi, Zulan, Schumacher, William A, Seiler, Steven M, Slusarchyk, William A, Treuner, Uwe, Zahler, Robert, Zhao, Guohua, Bisacchi, Gregory S

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Synthesis of potent and highly selective inhibitors of human tryptase von Slusarchyk, William A., Bolton, Scott A., Hartl, Karen S., Huang, Ming-Hsing, Jacobs, Glenn, Meng, Wei, Ogletree, Martin L., Pi, Zulan, Schumacher, William A., Seiler, Steven M., Sutton, James C., Treuner, Uwe, Zahler, Robert, Zhao, Guohua, Bisacchi, Gregory S.

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Synthesis of potent and highly selective nonguanidine azetidinone inhibitors of human tryptase von BISACCHI, Gregory S, SLUSARCHYK, William A, TREUNER, Uwe, ZAHLER, Robert, GUOHUA ZHAO, SEILER, Steven M, BOLTON, Scott A, HARTL, Karen S, JACOBS, Glenn, MATHUR, Arvind, WEI MENG, OGLETREE, Martin L, ZULAN PI, SUTTON, James C

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Discovery of Potent and Muscle Selective Androgen Receptor Modulators through Scaffold Modifications von Li, James J, Sutton, James C, Nirschl, Alexandra, Zou, Yan, Wang, Haixia, Sun, Chongqing, Pi, Zulan, Johnson, Rebecca, Krystek, Stanley R, Seethala, Ramakrishna, Golla, Rajasree, Sleph, Paul G, Beehler, Blake C, Grover, Gary J, Fura, Aberra, Vyas, Viral P, Li, Cindy Y, Gougoutas, Jack Z, Galella, Michael A, Zahler, Robert, Ostrowski, Jacek, Hamann, Lawrence G

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Identification of 6‑Hydroxypyrimidin-4(1H)‑one-3-carboxamides as Potent and Orally Active APJ Receptor Agonists von Pi, Zulan, Johnson, James A, Meng, Wei, Phillips, Monique, Schumacher, William A, Bostwick, Jeffrey S, Gargalovic, Peter S, Onorato, Joelle M, Generaux, Claudia N, Wang, Tao, He, Yan, Gordon, David A, Wexler, Ruth R, Finlay, Heather J

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Identification of Reversible Small Molecule Inhibitors of Endothelial Lipase (EL) That Demonstrate HDL‑C Increase In Vivo von Tora, George, Kim, Soong-Hoon, Pi, Zulan, Johnson, James A, Jiang, Ji, Phillips, Monique, Lloyd, John, Abell, Lynn M, Lu, Hao, Locke, Gregory, Adam, Leonard P, Taylor, David S, Yin, Xiaohong, Behnia, Kamelia, Zhao, Lei, Yang, Richard, Basso, Michael, Caporuscio, Christian, Chen, Alice Ye, Liu, Eddie, Kirshgessner, Todd, Onorato, Joelle M, Ryan, Carol, Traeger, Sarah C, Gordon, David, Wexler, Ruth R, Finlay, Heather J

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Identification of substituted benzothiazole sulfones as potent and selective inhibitors of endothelial lipase von Kim, Soong-Hoon, Johnson, James A., Jiang, Ji, Parkhurst, Brandon, Phillips, Monique, Pi, Zulan, Qiao, Jennifer X., Tora, George, Ye Chen, Alice, Liu, Eddie, Yin, Xiaohong, Yang, Richard, Zhao, Lei, Taylor, David S., Basso, Michael, Behnia, Kamelia, Onorato, Joelle, Chen, Xue-Qing, Abell, Lynn M., Lu, Hao, Locke, Gregory, Caporuscio, Christian, Adam, Leonard P., Gordon, David, Wexler, Ruth R., Finlay, Heather J.

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Corrigendum to “Identification of substituted benzothiazole sulfones as potent and selective inhibitors of endothelial lipase” [Bioorg. Med. Chem. Lett. 29 (2019) 1918–1921] von Kim, Soong-Hoon, Johnson, James A., Jiang, Ji, Parkhurst, Brandon, Phillips, Monique, Pi, Zulan, Qiao, Jennifer X., Tora, George, Ye Chen, Alice, Liu, Eddie, Yin, Xiaohong, Yang, Richard, Zhao, Lei, Taylor, David S., Basso, Michael, Behnia, Kamelia, Onorato, Joelle, Chen, Xue-Qing, Abell, Lynn M., Lu, Hao, Locke, Gregory, Caporuscio, Christian, Adam, Leonard P., Gordon, David, Wexler, Ruth R., Finlay, Heather J.

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2-Aminothiazole based P2Y(1) antagonists as novel antiplatelet agents von Pi, Zulan, Sutton, James, Lloyd, John, Hua, Ji, Price, Laura, Wu, Qimin, Chang, Ming, Zheng, Joanna, Rehfuss, Robert, Huang, Christine S, Wexler, Ruth R, Lam, Patrick Y S

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Pseudosaccharin amines as potent and selective KV1.5 blockers von Lloyd, John, Finlay, Heather J., Kover, Alexander, Johnson, James, Pi, Zulan, Jiang, Ji, Neels, James, Cavallaro, Cullen, Wexler, Ruth, Conder, Mary Lee, Shi, Hong, Li, Danshi, Sun, Huabin, Chimalakonda, Anjaneya, Huang, Christine, Salvati, Mark, Levesque, Paul

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Pseudosaccharin amines as potent and selective K V 1.5 blockers von Lloyd, John, Finlay, Heather J., Kover, Alexander, Johnson, James, Pi, Zulan, Jiang, Ji, Neels, James, Cavallaro, Cullen, Wexler, Ruth, Conder, Mary Lee, Shi, Hong, Li, Danshi, Sun, Huabin, Chimalakonda, Anjaneya, Huang, Christine, Salvati, Mark, Levesque, Paul

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Sulfonylated Benzothiazoles as Inhibitors of Endothelial Lipase von Johnson, James A, Tora, George, Pi, Zulan, Phillips, Monique, Yin, Xiaohong, Yang, Richard, Zhao, Lei, Chen, Alice Y, Taylor, David S, Basso, Michael, Rose, Anne, Behnia, Kamelia, Onorato, Joelle, Chen, Xue-Qing, Abell, Lynn M, Lu, Hao, Locke, Gregory, Caporuscio, Christian, Galella, Michael, Adam, Leonard P, Gordon, David, Wexler, Ruth R, Finlay, Heather J

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2-Aminothiazole based P2Y1 antagonists as novel antiplatelet agents von Pi, Zulan, Sutton, James, Lloyd, John, Hua, Ji, Price, Laura, Wu, Qimin, Chang, Ming, Zheng, Joanna, Rehfuss, Robert, Huang, Christine S., Wexler, Ruth R., Lam, Patrick Y.S.

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Discovery of nonbenzamidine factor VIIa inhibitors using a biaryl acid scaffold von Bolton, Scott A., Sutton, James C., Anumula, Rushith, Bisacchi, Gregory S., Jacobson, Bruce, Slusarchyk, William A., Treuner, Uwe D., Wu, Shung C., Zhao, Guohua, Pi, Zulan, Sheriff, Steven, Smirk, Rebecca A., Bisaha, Sharon, Cheney, Daniel L., Wei, Anzhi, Schumacher, William A., Hartl, Karen S., Liu, Eddie, Zahler, Robert, Seiler, Steven M.

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Conformationally Constrained ortho- Anilino Diaryl Ureas: Discovery of 1-(2-(1′-Neopentylspiro[indoline-3,4′-piperidine]-1-yl)phenyl)-3-(4-(trifluoromethoxy)phenyl)urea, a Potent,... von Qiao, Jennifer X., Wang, Tammy C., Ruel, Réjean, Thibeault, Carl, L’Heureux, Alexandre, Schumacher, William A., Spronk, Steven A., Hiebert, Sheldon, Bouthillier, Gilles, Lloyd, John, Pi, Zulan, Schnur, Dora M., Abell, Lynn M., Hua, Ji, Price, Laura A., Liu, Eddie, Wu, Qimin, Steinbacher, Thomas E., Bostwick, Jeffrey S., Chang, Ming, Zheng, Joanna, Gao, Qi, Ma, Baoqing, McDonnell, Patricia A., Huang, Christine S., Rehfuss, Robert, Wexler, Ruth R., Lam, Patrick Y. S.

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Electron Deficient Dienes. 2. One Step Synthesis of a Coumarin-Fused Electron Deficient Diene and its Inverse Electron Demand Diels-Alder Reactions with Enamines von Bodwell, Graham J., Pi, Zulan, Pottie, Ian R.

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1,2-Benzisothiazol-3-one 1,1-Dioxide Inhibitors of Human Mast Cell Tryptase von Combrink, Keith D, Gülgeze, H. Belgin, Meanwell, Nicholas A, Pearce, Bradley C, Zulan, Pi, Bisacchi, Gregory S, Roberts, Daniel G. M, Stanley, Paul, Seiler, Steven M

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