A core in vitro genotoxicity battery comprising the Ames test plus the in vitro micronucleus test is sufficient to detect rodent carcinogens and in vivo genotoxins von Kirkland, David, Reeve, Lesley, Gatehouse, David, Vanparys, Philippe

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How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop von Kirkland, David, Pfuhler, Stefan, Tweats, David, Aardema, Marilyn, Corvi, Raffaella, Darroudi, Firouz, Elhajouji, Azeddine, Glatt, Hansruedi, Hastwell, Paul, Hayashi, Makoto, Kasper, Peter, Kirchner, Stephan, Lynch, Anthony, Marzin, Daniel, Maurici, Daniela, Meunier, Jean-Roc, Müller, Lutz, Nohynek, Gerhard, Parry, James, Parry, Elizabeth, Thybaud, Veronique, Tice, Ray, van Benthem, Jan, Vanparys, Philippe, White, Paul

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Reduction of use of animals in regulatory genotoxicity testing: Identification and implementation opportunities—Report from an ECVAM workshop von Pfuhler, Stefan, Kirkland, David, Kasper, Peter, Hayashi, Makoto, Vanparys, Philippe, Carmichael, Paul, Dertinger, Stephen, Eastmond, David, Elhajouji, Azeddine, Krul, Cyrille, Rothfuss, Andreas, Schoening, Gabriele, Smith, Andrew, Speit, Guenter, Thomas, Claire, van Benthem, Jan, Corvi, Raffaella

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review of the implementation of the embryonic stem cell test (EST) von Marx-Stoelting, Philip, Adriaens, Els, Ahr, Hans-Jurgen, Bremer, Susanne, Garthoff, Bernward, Gelbke, Heinz-Peter, Piersma, Aldert, Pellizzer, Cristian, Reuter, Ulrike, Rogiers, Vera, Schenk, Barbara, Schwengberg, Silke, Seiler, Andrea, Spielmann, Horst, Steemans, Margino, Stedman, Donald B

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Practical Application of Three Validated In Vitro Embryotoxicity Tests von Spielmann, H, Seiler, A, Bremer, S, Hareng, L, Hartung, T, Ahr, H, Faustman, E, Haas, U, Moffat, G.J, Nau, H

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Automated analysis of contractility in the embryonic stem cell test, a novel approach to assess embryotoxicity von Peters, Annelieke K., Wouwer, Gert Van de, Weyn, Barbara, Verheyen, Geert R., Vanparys, Philippe, Gompel, Jacques Van

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Preface von Corvi, Raffaella, Vanparys, Philippe

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Flow cytometric analysis of micronucleated reticulocytes: Time- and dose-dependent response of known mutagens in mice, using multiple blood sampling von De Boeck, Marlies, van der Leede, Bas-jan, Van Goethem, Freddy, De Smedt, Ann, Steemans, Margino, Lampo, Ann, Vanparys, Philippe

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Interlaboratory validation of the ToxTracker assay: An in vitro reporter assay for mechanistic genotoxicity assessment von Hendriks, Giel, Adriaens, Els, Allemang, Ashley, Clements, Julie, Cole, Gabrielle, Derr, Remco, Engel, Maria, Hamel, Annie, Kidd, Darren, Kellum, Stephanie, Kiyota, Tomomi, Myhre, Abby, Naëssens, Valerie, Pfuhler, Stefan, Roy, Marise, Settivari, Raja, Schuler, Maik, Zeller, Andreas, Benthem, Jan, Vanparys, Philippe, Kirkland, David

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Can in vitro mammalian cell genotoxicity test results be used to complement positive results in the Ames test and help predict carcinogenic or in vivo genotoxic activity? I. Report... von Kirkland, David, Zeiger, Errol, Madia, Federica, Gooderham, Nigel, Kasper, Peter, Lynch, Anthony, Morita, Takeshi, Ouedraogo, Gladys, Parra Morte, Juan Manuel, Pfuhler, Stefan, Rogiers, Vera, Schulz, Markus, Thybaud, Veronique, van Benthem, Jan, Vanparys, Philippe, Worth, Andrew, Corvi, Raffaella

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Improvement of the Bovine Corneal Opacity and Permeability (BCOP) assay as an in vitro alternative to the Draize rabbit eye irritation test von Verstraelen, Sandra, Jacobs, An, De Wever, Bart, Vanparys, Philippe

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ECVAM retrospective validation of in vitro micronucleus test (MNT) von Corvi, Raffaella, Albertini, Silvio, Hartung, Thomas, Hoffmann, Sebastian, Maurici, Daniela, Pfuhler, Stefan, van Benthem, Jan, Vanparys, Philippe

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ECVAM prevalidation study on in vitro cell transformation assays: General outline and conclusions of the study von Corvi, Raffaella, Aardema, Marilyn J., Gribaldo, Laura, Hayashi, Makoto, Hoffmann, Sebastian, Schechtman, Leonard, Vanparys, Philippe

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A novel genotoxin-specific qPCR array based on the metabolically competent human HepaRG™ cell line as a rapid and reliable tool for improved in vitro hazard assessment von Ates, Gamze, Mertens, Birgit, Heymans, Anja, Verschaeve, Luc, Milushev, Dimiter, Vanparys, Philippe, Roosens, Nancy H. C., De Keersmaecker, Sigrid C. J., Rogiers, Vera, Doktorova, Tatyana Y.

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Application of in vitro cell transformation assays in regulatory toxicology for pharmaceuticals, chemicals, food products and cosmetics von Vanparys, Philippe, Corvi, Raffaella, Aardema, Marilyn J., Gribaldo, Laura, Hayashi, Makoto, Hoffmann, Sebastian, Schechtman, Leonard

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In silico tools and transcriptomics analyses in the mutagenicity assessment of cosmetic ingredients: a proof-of-principle on how to add weight to the evidence von Ates, Gamze, Raitano, Giuseppa, Heymans, Anja, Van Bossuyt, Melissa, Vanparys, Philippe, Mertens, Birgit, Chesne, Christophe, Roncaglioni, Alessandra, Milushev, Dimiter, Benfenati, Emilio, Rogiers, Vera, Doktorova, Tatyana Y

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A review of the implementation of the embryonic stem cell test (EST). The report and recommendations of an ECVAM/ReProTect Workshop von Marx-Stoelting, Philip, Adriaens, Els, Ahr, Hans-Jürgen, Bremer, Susanne, Garthoff, Bernward, Gelbke, Heinz-Peter, Piersma, Aldert, Pellizzer, Cristian, Reuter, Ulrike, Rogiers, Vera, Schenk, Barbara, Schwengberg, Silke, Seiler, Andrea, Spielmann, Horst, Steemans, Margino, Stedman, Donald B, Vanparys, Philippe, Vericat, Joan Albert, Verwei, Miriam, van der Water, Femke, Weimer, Marc, Schwarz, Michael

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Evaluation of the Embryotoxic Potency of Compounds in a Newly Revised High Throughput Embryonic Stem Cell Test von Peters, Annelieke K., Steemans, Margino, Hansen, Erik, Mesens, Natalie, Verheyen, Geert R., Vanparys, Philippe

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Development of a new opacitometer for the bovine corneal opacity and permeability (BCOP) assay von Van Goethem, Freddy, Hansen, Erik, Sysmans, Marc, De Smedt, Ann, Vanparys, Philippe, Van Gompel, Jacky

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A 96-well flow cytometric screening assay for detecting in vitro phospholipidosis-induction in the drug discovery phase von Natalie, Mesens, Margino, Steemans, Erik, Hansen, Annelieke, Peters, Geert, Verheyen, Philippe, Vanparys

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