Common Risk Alleles for Inflammatory Diseases Are Targets of Recent Positive Selection von Raj, Towfique, Kuchroo, Manik, Replogle, Joseph M., Raychaudhuri, Soumya, Stranger, Barbara E., De Jager, Philip L.

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Neuropathological correlates and genetic architecture of microglial activation in elderly human brain von Felsky, Daniel, Roostaei, Tina, Nho, Kwangsik, Risacher, Shannon L., Bradshaw, Elizabeth M., Petyuk, Vlad, Schneider, Julie A., Saykin, Andrew, Bennett, David A., De Jager, Philip L.

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Nuclei multiplexing with barcoded antibodies for single-nucleus genomics von Gaublomme, Jellert T., Li, Bo, McCabe, Cristin, Knecht, Abigail, Yang, Yiming, Drokhlyansky, Eugene, Van Wittenberghe, Nicholas, Waldman, Julia, Dionne, Danielle, Nguyen, Lan, De Jager, Philip L., Yeung, Bertrand, Zhao, Xinfang, Habib, Naomi, Rozenblatt-Rosen, Orit, Regev, Aviv

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Brain expression of the vascular endothelial growth factor gene family in cognitive aging and alzheimer’s disease von Mahoney, Emily R., Dumitrescu, Logan, Moore, Annah M., Cambronero, Francis E., De Jager, Philip L., Koran, Mary Ellen I., Petyuk, Vladislav A., Robinson, Renã A. S., Goyal, Sandeep, Schneider, Julie A., Bennett, David A., Jefferson, Angela L., Hohman, Timothy J.

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Age at surgical menopause influences cognitive decline and Alzheimer pathology in older women von BOVE, Riley, SECOR, Elizabeth, CHIBNIK, Lori B, BARNES, Lisa L, SCHNEIDER, Julie A, BENNETT, David A, DE JAGER, Philip L

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Parsing the Interferon Transcriptional Network and Its Disease Associations von Mostafavi, Sara, Yoshida, Hideyuki, Moodley, Devapregasan, LeBoité, Hugo, Rothamel, Katherine, Raj, Towfique, Ye, Chun Jimmie, Chevrier, Nicolas, Zhang, Shen-Ying, Feng, Ting, Lee, Mark, Casanova, Jean-Laurent, Clark, James D., Hegen, Martin, Telliez, Jean-Baptiste, Hacohen, Nir, De Jager, Philip L., Regev, Aviv, Mathis, Diane, Benoist, Christophe

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Brain proteome-wide association study implicates novel proteins in depression pathogenesis von Wingo, Thomas S., Liu, Yue, Gerasimov, Ekaterina S., Gockley, Jake, Logsdon, Benjamin A., Duong, Duc M., Dammer, Eric B., Lori, Adriana, Kim, Paul J., Ressler, Kerry J., Beach, Thomas G., Reiman, Eric M., Epstein, Michael P., De Jager, Philip L., Lah, James J., Bennett, David A., Seyfried, Nicholas T., Levey, Allan I., Wingo, Aliza P.

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Genome-wide Chromatin State Transitions Associated with Developmental and Environmental Cues von Zhu, Jiang, Adli, Mazhar, Zou, James Y., Verstappen, Griet, Coyne, Michael, Zhang, Xiaolan, Durham, Timothy, Miri, Mohammad, Deshpande, Vikram, De Jager, Philip L., Bennett, David A., Houmard, Joseph A., Muoio, Deborah M., Onder, Tamer T., Camahort, Ray, Cowan, Chad A., Meissner, Alexander, Epstein, Charles B., Shoresh, Noam, Bernstein, Bradley E.

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A machine learning approach to brain epigenetic analysis reveals kinases associated with Alzheimer’s disease von Huang, Yanting, Sun, Xiaobo, Jiang, Huige, Yu, Shaojun, Robins, Chloe, Armstrong, Matthew J., Li, Ronghua, Mei, Zhen, Shi, Xiaochuan, Gerasimov, Ekaterina Sergeevna, De Jager, Philip L., Bennett, David A., Wingo, Aliza P., Jin, Peng, Wingo, Thomas S., Qin, Zhaohui S.

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Life Extension Factor Klotho Enhances Cognition von Dubal, Dena B., Yokoyama, Jennifer S., Zhu, Lei, Broestl, Lauren, Worden, Kurtresha, Wang, Dan, Sturm, Virginia E., Kim, Daniel, Klein, Eric, Yu, Gui-Qiu, Ho, Kaitlyn, Eilertson, Kirsten E., Yu, Lei, Kuro-o, Makoto, De Jager, Philip L., Coppola, Giovanni, Small, Gary W., Bennett, David A., Kramer, Joel H., Abraham, Carmela R., Miller, Bruce L., Mucke, Lennart

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Molecular estimation of neurodegeneration pseudotime in older brains von Mukherjee, Sumit, Heath, Laura, Preuss, Christoph, Jayadev, Suman, Garden, Gwenn A., Greenwood, Anna K., Sieberts, Solveig K., De Jager, Philip L., Ertekin-Taner, Nilüfer, Carter, Gregory W., Mangravite, Lara M., Logsdon, Benjamin A.

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Unified AI framework to uncover deep interrelationships between gene expression and Alzheimer’s disease neuropathologies von Beebe-Wang, Nicasia, Celik, Safiye, Weinberger, Ethan, Sturmfels, Pascal, De Jager, Philip L., Mostafavi, Sara, Lee, Su-In

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Serum metabolomic biomarkers of perceptual speed in cognitively normal and mildly impaired subjects with fasting state stratification von Borkowski, Kamil, Taha, Ameer Y., Pedersen, Theresa L., De Jager, Philip L., Bennett, David A., Arnold, Matthias, Kaddurah-Daouk, Rima, Newman, John W.

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Genes and Environment in Multiple Sclerosis project: A platform to investigate multiple sclerosis risk von Xia, Zongqi, White, Charles C., Owen, Emily K., Korff, Alina Von, Clarkson, Sarah R., McCabe, Cristin A., Cimpean, Maria, Winn, Phoebe A., Hoesing, Ashley, Steele, Sonya U., Cortese, Irene C. M., Chitnis, Tanuja, Weiner, Howard L., Reich, Daniel S., Chibnik, Lori B., Jager, Philip L. De

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Defining the role of the MHC in autoimmunity: a review and pooled analysis von Fernando, Michelle M A, Stevens, Christine R, Walsh, Emily C, De Jager, Philip L, Goyette, Philippe, Plenge, Robert M, Vyse, Timothy J, Rioux, John D

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Cascading epigenomic analysis for identifying disease genes from the regulatory landscape of GWAS variants von Ng, Bernard, Casazza, William, Kim, Nam Hee, Wang, Chendi, Farhadi, Farnush, Tasaki, Shinya, Bennett, David A, De Jager, Philip L, Gaiteri, Christopher, Mostafavi, Sara

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Unbiased classification of the elderly human brain proteome resolves distinct clinical and pathophysiological subtypes of cognitive impairment von Higginbotham, Lenora, Carter, E. Kathleen, Dammer, Eric B., Haque, Rafi U., Johnson, Erik C.B., Duong, Duc M., Yin, Luming, De Jager, Philip L., Bennett, David A., Felsky, Daniel, Tio, Earvin S., Lah, James J., Levey, Allan I., Seyfried, Nicholas T.

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Proximal and distal effects of genetic susceptibility to multiple sclerosis on the T cell epigenome von Roostaei, Tina, Klein, Hans-Ulrich, Ma, Yiyi, Felsky, Daniel, Kivisäkk, Pia, Connor, Sarah M., Kroshilina, Alexandra, Yung, Christina, Kaskow, Belinda J., Shao, Xiaorong, Rhead, Brooke, Ordovás, José M., Absher, Devin M., Arnett, Donna K., Liu, Jia, Patsopoulos, Nikolaos, Barcellos, Lisa F., Weiner, Howard L., De Jager, Philip L.

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Atlas of RNA editing events affecting protein expression in aged and Alzheimer’s disease human brain tissue von Ma, Yiyi, Dammer, Eric B., Felsky, Daniel, Duong, Duc M., Klein, Hans-Ulrich, White, Charles C., Zhou, Maotian, Logsdon, Benjamin A., McCabe, Cristin, Xu, Jishu, Wang, Minghui, Wingo, Thomas S., Lah, James J., Zhang, Bin, Schneider, Julie, Allen, Mariet, Wang, Xue, Ertekin-Taner, Nilüfer, Seyfried, Nicholas T., Levey, Allan I., Bennett, David A., De Jager, Philip L.

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Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors von Villani, Alexandra-Chloé, Satija, Rahul, Reynolds, Gary, Sarkizova, Siranush, Shekhar, Karthik, Fletcher, James, Griesbeck, Morgane, Butler, Andrew, Zheng, Shiwei, Lazo, Suzan, Jardine, Laura, Dixon, David, Stephenson, Emily, Nilsson, Emil, Grundberg, Ida, McDonald, David, Filby, Andrew, Li, Weibo, De Jager, Philip L., Rozenblatt-Rosen, Orit, Lane, Andrew A., Haniffa, Muzlifah, Regev, Aviv, Hacohen, Nir

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