Clinical Pharmacokinetics and Pharmacodynamics of Daratumumab von Kim, Kyeongmin, Phelps, Mitch A.

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Discovery and Mechanism of Highly Efficient Cyclic Cell-Penetrating Peptides von Qian, Ziqing, Martyna, Agnieszka, Hard, Ryan L, Wang, Jiang, Appiah-Kubi, George, Coss, Christopher, Phelps, Mitch A, Rossman, Jeremy S, Pei, Dehua

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Comprehensive toxicity and immunogenicity studies reveal minimal effects in mice following sustained dosing of extracellular vesicles derived from HEK293T cells von Zhu, Xiaohua, Badawi, Mohamed, Pomeroy, Steven, Sutaria, Dhruvitkumar S., Xie, Zhiliang, Baek, Alice, Jiang, Jinmai, Elgamal, Ola A., Mo, Xiaokui, Perle, Krista La, Chalmers, Jeffrey, Schmittgen, Thomas D., Phelps, Mitch A.

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miR-221 Silencing Blocks Hepatocellular Carcinoma and Promotes Survival von PARK, Jong-Kook, KOGURE, Takayuki, SCHMITTGEN, Thomas D, NUOVO, Gerard J, JINMAI JIANG, LEI HE, KIM, Ji Hye, PHELPS, Mitch A, PAPENFUSS, Tracey L, CROCE, Carlo M, PATEL, Tushar

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Multi-Institutional Phase II Study of Selumetinib in Patients With Metastatic Biliary Cancers von BEKAII-SAAB, Tanios, PHELPS, Mitch A, VASKO, Vasily V, BLOOMSTON, Mark, MARSH, William, AUSTIN DOYLE, L, ELLISON, Gilian, GREVER, Michael, RINGEL, Matthew D, VILLALONA-CALERO, Miguel A, XIAOBAI LI, SAJI, Motoyasu, GOFF, Laura, WOOK KAUH, John Sae, O'NEIL, Bert H, BALSOM, Stephanie, BALINT, Catherine, LIERSEMANN, Ryan

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Increased renal elimination of endogenous and synthetic pyrimidine nucleosides in concentrative nucleoside transporter 1 deficient mice von Persaud, Avinash K., Bernier, Matthew C., Massey, Michael A., Agrawal, Shipra, Kaur, Tejinder, Nayak, Debasis, Xie, Zhiliang, Weadick, Brenna, Raj, Ruchika, Hill, Kasey, Abbott, Nicole, Joshi, Arnav, Anabtawi, Nadeen, Bryant, Claire, Somogyi, Arpad, Cruz-Monserrate, Zobeida, Amari, Foued, Coppola, Vincenzo, Sparreboom, Alex, Baker, Sharyn D., Unadkat, Jashvant D., Phelps, Mitch A., Govindarajan, Rajgopal

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Discovery of Anticancer Agents of Diverse Natural Origin von Aldrich, Leslie N, Burdette, Joanna E, Carcache de Blanco, Esperanza, Coss, Christopher C, Eustaquio, Alessandra S, Fuchs, James R, Kinghorn, A. Douglas, MacFarlane, Amanda, Mize, Brittney K, Oberlies, Nicholas H, Orjala, Jimmy, Pearce, Cedric J, Phelps, Mitch A, Rakotondraibe, Liva Harinantenaina, Ren, Yulin, Soejarto, Djaja Doel, Stockwell, Brent R, Yalowich, Jack C, Zhang, Xiaoli

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Irinotecan pharmacogenetics: a finished puzzle? von Phelps, Mitch A, Sparreboom, Alex

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Decoupling FcRn and Tumor Contributions to Elevated Immune Checkpoint Inhibitor Clearance in Cancer Cachexia von Vu, Trang T, Kim, Kyeongmin, Manna, Millennium, Thomas, Justin, Remaily, Bryan, Montgomery, Emma J, Costa, Travis, Granchie, Lauren, Xie, Zhiliang, Guo, Yizhen, Chen, Min, Castillo, Alyssa Marie M, Kulp, Samuel K, Mo, Xiaokui, Nimmagadda, Sridhar, Gregorevic, Paul, Owen, Dwight H, Ganesan, Latha P, Mace, Thomas A, Coss, Christopher C, Phelps, Mitch A

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Replication Study: Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs von Wang, Hongyan, Radomska, Hanna S, Phelps, Mitch A

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Author Correction: Increased renal elimination of endogenous and synthetic pyrimidine nucleosides in concentrative nucleoside transporter 1 deficient mice von Persaud, Avinash K., Bernier, Matthew C., Massey, Michael A., Agrawal, Shipra, Kaur, Tejinder, Nayak, Debasis, Xie, Zhiliang, Weadick, Brenna, Raj, Ruchika, Hill, Kasey, Abbott, Nicole, Joshi, Arnav, Anabtawi, Nadeen, Bryant, Claire, Somogyi, Arpad, Cruz-Monserrate, Zobeida, Amari, Foued, Coppola, Vincenzo, Sparreboom, Alex, Baker, Sharyn D., Unadkat, Jashvant D., Phelps, Mitch A., Govindarajan, Rajgopal

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Inhibition of androgen/AR signaling inhibits diethylnitrosamine (DEN) induced tumour initiation and remodels liver immune cell networks von Helms, Timothy H., Mullins, Riley D., Thomas-Ahner, Jennifer M., Kulp, Samuel K., Campbell, Moray J., Lucas, Fabienne, Schmidt, Nathan, LeMoine, Dana M., Getaneh, Surafel, Xie, Zhiliang, Phelps, Mitch A., Clinton, Steven K., Coss, Christopher C.

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Proteomic characterization of circulating extracellular vesicles identifies novel serum myeloma associated markers von Harshman, Sean W., Canella, Alessandro, Ciarlariello, Paul D., Agarwal, Kitty, Branson, Owen E., Rocci, Alberto, Cordero, Hector, Phelps, Mitch A., Hade, Erinn M., Dubovsky, Jason A., Palumbo, Antonio, Rosko, Ashley, Byrd, John C., Hofmeister, Craig C., Benson, Don M., Paulaitis, Michael E., Freitas, Michael A., Pichiorri, Flavia

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Approaches to handling missing or “problematic” pharmacology data: Pharmacokinetics von Irby, Donald J., Ibrahim, Mustafa E., Dauki, Anees M., Badawi, Mohamed A., Illamola, Sílvia M., Chen, Mingqing, Wang, Yuhuan, Liu, Xiaoxi, Phelps, Mitch A., Mould, Diane R.

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Phase II Study of Flavopiridol in Relapsed Chronic Lymphocytic Leukemia Demonstrating High Response Rates in Genetically High-Risk Disease von Lin, Thomas S., Ruppert, Amy S., Johnson, Amy J., Fischer, Beth, Heerema, Nyla A., Andritsos, Leslie A., Blum, Kristie A., Flynn, Joseph M., Jones, Jeffrey A., Hu, Weihong, Moran, Mollie E., Mitchell, Sarah M., Smith, Lisa L., Wagner, Amy J., Raymond, Chelsey A., Schaaf, Larry J., Phelps, Mitch A., Villalona-Calero, Miguel A., Grever, Michael R., Byrd, John C.

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CYP3A5 influences oral tacrolimus pharmacokinetics and timing of acute kidney injury following allogeneic hematopoietic stem cell transplantation von Seligson, Nathan D, Zhang, Xunjie, Zemanek, Mark C, Johnson, Jasmine A, VanGundy, Zachary, Wang, Danxin, Phelps, Mitch A, Roddy, Julianna, Hofmeister, Craig C, Li, Junan, Poi, Ming J

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Phyllanthusmin Derivatives Induce Apoptosis and Reduce Tumor Burden in High-Grade Serous Ovarian Cancer by Late-Stage Autophagy Inhibition von Young, Alexandria N, Herrera, Denisse, Huntsman, Andrew C, Korkmaz, Melissa A, Lantvit, Daniel D, Mazumder, Sarmistha, Kolli, Shamalatha, Coss, Christopher C, King, Salane, Wang, Hongyan, Swanson, Steven M, Kinghorn, A Douglas, Zhang, Xiaoli, Phelps, Mitch A, Aldrich, Leslie N, Fuchs, James R, Burdette, Joanna E

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Target specificity, in vivo pharmacokinetics, and efficacy of the putative STAT3 inhibitor LY5 in osteosarcoma, Ewing's sarcoma, and rhabdomyosarcoma von Yu, Peter Y, Gardner, Heather L, Roberts, Ryan, Cam, Hakan, Hariharan, Seethalakshmi, Ren, Ling, LeBlanc, Amy K, Xiao, Hui, Lin, Jiayuh, Guttridge, Denis C, Mo, Xiaokui, Bennett, Chad E, Coss, Christopher C, Ling, Yonghua, Phelps, Mitch A, Houghton, Peter, London, Cheryl A

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Clinical response and pharmacokinetics from a phase 1 study of an active dosing schedule of flavopiridol in relapsed chronic lymphocytic leukemia von Phelps, Mitch A., Lin, Thomas S., Johnson, Amy J., Hurh, Eunju, Rozewski, Darlene M., Farley, Katherine L., Wu, Di, Blum, Kristie A., Fischer, Beth, Mitchell, Sarah M., Moran, Mollie E., Brooker-McEldowney, Michelle, Heerema, Nyla A., Jarjoura, David, Schaaf, Larry J., Byrd, John C., Grever, Michael R., Dalton, James T.

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Low active loading of cargo into engineered extracellular vesicles results in inefficient miRNA mimic delivery von Sutaria, Dhruvitkumar S., Jiang, Jinmai, Elgamal, Ola A., Pomeroy, Steven M., Badawi, Mohamed, Zhu, Xiaohua, Pavlovicz, Ryan, Azevedo-Pouly, Ana Clara P., Chalmers, Jeffrey, Li, Chenglong, Phelps, Mitch A., Schmittgen, Thomas D.

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