Expanding the Functional Repertoire of CTD Kinase I and RNA Polymerase II:  Novel PhosphoCTD-Associating Proteins in the Yeast Proteome von Phatnani, Hemali P, Jones, Janice C, Greenleaf, Arno L

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Phospho-Carboxyl-Terminal Domain Binding and the Role of a Prolyl Isomerase in Pre-mRNA 3′-End Formation von Morris, Daniel P., Phatnani, Hemali P., Greenleaf, Arno L.

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C-terminal Repeat Domain Kinase I Phosphorylates Ser2 and Ser5 of RNA Polymerase II C-terminal Domain Repeats von Jones, Janice C., Phatnani, Hemali P., Haystead, Timothy A., MacDonald, Justin A., Alam, S. Munir, Greenleaf, Arno L.

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Cell environment shapes TDP-43 function with implications in neuronal and muscle disease von Šušnjar, Urša, Škrabar, Neva, Brown, Anna-Leigh, Abbassi, Yasmine, Phatnani, Hemali, Cortese, Andrea, Cereda, Cristina, Bugiardini, Enrico, Cardani, Rosanna, Meola, Giovanni, Ripolone, Michela, Moggio, Maurizio, Romano, Maurizio, Secrier, Maria, Fratta, Pietro, Buratti, Emanuele

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Solution Structure of the Set2-Rpb1 Interacting Domain of Human Set2 and Its Interaction with the Hyperphosphorylated C-Terminal Domain of Rpb1 von Li, Ming, Hemali P. Phatnani, Guan, Ziqiang, Harvey Sage, Greenleaf, Arno L., Zhou, Pei

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NOS1AP is a novel molecular target and critical factor in TDP-43 pathology von Cappelli, S., Spalloni, A., Feiguin, F., Visani, G., Susnjar, U., Brown, A.L., Bardi, M. de, Borsellino, G., Secrier, M., Phatnani, H., Romano, M., Fratta, P., Longone, P., Buratti, E.

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Cell environment shapes TDP-43 function with implications in neuronal and muscle disease von Susnjar, U., Skrabar, N., Brown, A.L., Abbassi, Y., Phatnani, H., Cortese, A., Cereda, C., Bugiardini, E., Cardani, R., Meola, G., Ripolone, M., Moggio, M., Romano, M., Secrier, M., Fratta, P., Buratti, E.

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TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A von Brown, A.L., Wilkins, O.G., Keuss, M.J., Hill, S.E., Zanovello, M., Lee, W.C., Bampton, A., Lee, F.C.Y., Masino, L., Qi, Y.A., Bryce-Smith, S., Gatt, A., Hallegger, M., Fagegaltier, D., Phatnani, H., Newcombe, J., Gustavsson, E.K., Seddighi, S., Reyes, J.F., Coon, S.L., Ramos, D., Schiavo, G., Fisher, E.M.C., Raj, T., Secrier, M., Lashley, T., Ule, J., Buratti, E., Humphrey, J., Ward, M.E., Fratta, P.

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Unexpected similarities between C9ORF72 and sporadic forms of ALS/FTD suggest a common disease mechanism von Conlon, E.G., Fagegaltier, D., Agius, P., Davis-Porada, J., Gregory, J., Hubbard, I., Kang, K., Kim, D., Phatnani, H., Shneider, N.A., Manley, J.L.

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Unexpected similarities between C9ORF72 and sporadic forms of ALS/FTD suggest a common disease mechanism von Conlon, EG, Fagegaltier, D, Agius, P, Davis-Porada, J, Gregory, J, Hubbard, I, Kang, K, Kim, D, Phatnani, H, Shneider, NA, Manley, JL

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Exome sequencing in amyotrophic lateral sclerosis implicates a novel gene, DNAJC7, encoding a heat-shock protein von Farhan, S.M.K, Howrigan, D.P, Abbott, L.E, Klim, J.R, Topp, S.D, Byrnes, A.E, Churchhouse, C, Phatnani, H, Smith, B.N, Rampersaud, E, Wu, G, Wuu, J, Shatunov, A, Iacoangeli, A, Al Khleifat, A, Mordes, D.A, Ghosh, S, Eggan, K, Rademakers, R, McCauley, J.L, Schüle, R, Züchner, S, Benatar, M, Taylor, J.P, Nalls, M, Gotkine, M, Shaw, P.J, Morrison, K.E, Al-Chalabi, A, Traynor, B, Shaw, C.E, Goldstein, D.B, Harms, M.B, Daly, M.J, Neale, B.M

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Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia von Prudencio, M, Humphrey, J, Pickles, S, Brown, A-L, Hill, SE, Kachergus, J, Shi, J, Heckman, M, Spiegel, M, Cook, C, Song, Y, Yue, M, Daughrity, L, Carlomagno, Y, Jansen-West, K, Fernandez De Castro, C, DeTure, M, Koga, S, Wang, Y-C, Sivakumar, P, Bodo, C, Candalija, A, Talbot, K, Selvaraj, BT, Burr, K, Chandran, S, Newcombe, J, Lashley, T, Hubbard, I, Catalano, D, Kim, D, Propp, N, Fennessey, S, Fagegaltier, D, Phatnani, H, Secrier, M, Fisher, EM, Oskarsson, B, van Blitterswijk, M, Rademakers, R, Graff-Radford, NR, Boeve, B, Knopman, DS, Petersen, R, Josephs, K, Thompson, EA, Raj, T, Ward, ME, Dickson, D, Gendron, TF, Fratta, P, Petrucelli, L

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Human genetics and neuropathology suggest a link between miR-218 and amyotrophic lateral sclerosis pathophysiology von Reichenstein, I, Eitan, C, Diaz-Garcia, S, Haim, G, Magen, I, Siany, A, Hoye, M.L, Rivkin, N, Olender, T, Toth, B, Ravid, R, Mandelbaum, A.D, Yanowski, E, Liang, J, Rymer, J.K, Levy, R, Beck, G, Ainbinder, E, Farhan, S.M.K, Lennox, K.A, Bode, N.M, Behlke, M.A, Möller, T, Saxena, S, Moreno, C.A.M, Costaguta, G, van Eijk, K.R, Phatnani, H, Al-Chalabi, A, Başak, A.N, van den Berg, L.H, Hardiman, O, Landers, J.E, Mora, J.S, Morrison, K.E, Shaw, P.J, Veldink, J.H, Pfaff, S.L, Yizhar, O, Gross, C, Brown, R.H, Ravits, J.M, Harms, M.B, Miller, T.M, Hornstein, E

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Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia von Tam, OH, Rozhkov, NV, Shaw, R, Kim, D, Hubbard, I, Fennessey, S, Propp, N, Fagegaltier, D, Harris, BT, Ostrow, LW, Phatnani, H, Ravits, J, Dubnau, J, Hammell, MG, Kwan, J, Sareen, D, Broach, JR, Simmons, Z, Arcila-Londono, X, Lee, EB, Van Deerlin, VM, Shneider, NA, Fraenkel, E, Baas, F, Zaitlen, N, Berry, JD, Malaspina, A, Fratta, P, Cox, GA, Thompson, LM, Finkbeiner, S, Dardiotis, E, Miller, TM, Chandran, S, Pal, S, Hornstein, E, MacGowan, DJ, Heiman-Patterson, T, Patsopoulos, NA, Butovsky, O, Nath, A, Bowser, R, Harms, M, Aronica, E, Poss, M, Phillips-Cremins, J, Crary, J, Atassi, N, Lange, DJ, Adams, DJ, Stefanis, L, Gotkine, M, Baloh, R, Babu, S, Raj, T, Paganoni, S, Shalem, O, Smith, C, Zhang, B

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Genome-wide Analyses Identify KIF5A as a Novel ALS Gene von Kenna, KP, Chia, R, Dominov, JA, Keagle, P, van Vugt, JJFA, Geiger, JT, Shankaracharya, Smith, BN, Marangi, G, Topp, SD, Abramzon, Y, Kenna, A, Mora, G, Riva, N, La Bella, V, Conforti, FL, Borghero, G, Salvi, F, Logullo, FO, D'Alfonso, S, Corrado, L, Capasso, M, Ferrucci, L, Moreno, CDAM, Kamalakaran, S, Goldstein, DB, Gitler, AD, Abhyankar, A, Zody, MC, Kaye, J, LeNail, A, Fraenkel, E, Svendsen, CN, Van Eyk, JE, Berry, JD, Miller, TM, Kolb, SJ, Cudkowicz, M, Benatar, M, Rampersaud, E, Wu, G, Wuu, J, SLAGEN Consortium, Verde, F, Tiloca, C, Comi, GP, French ALS Consortium, Corcia, P, Laaksovirta, H, Myllykangas, L, Jansson, L, Valori, M, Johnson, JO, Arepalli, S, Sapp, PC, McKenna-Yasek, D, Polak, M, Asress, S, Al-Sarraj, S, Troakes, C, de Belleroche, J, Baas, F, Ten Asbroek, ALMA, Floeter, MK, Ravits, JM, Kirby, J, Pioro, EP, Pamphlett, R, Broach, J, Dunckley, TL, Brady, CB, Le Ber, I, Mouzat, K, Heiman-Patterson, TD, Van Den Bosch, L, Strom, TM, Shatunov, A, Van Eijk, KR, Moisse, M, Van Es, MA, Van Blitterswijk, M, Mora, JS, Turner, MR, Talbot, K, Fifita, JA, Blair, IP, Rouleau, GA, Esteban-Pérez, J, Rogaeva, E, Rothstein, JD, Cooper-Knock, J, Goutman, SA, Van Damme, P, Robberecht, W, Sabatelli, M, Lunetta, C, Weishaupt, JH, Chiò, A, Shaw, CE, Traynor, BJ

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Genome-wide Analyses Identify KIF5A as a Novel ALS Gene von Kenna, KP, Chia, R, Dominov, JA, Keagle, P, van Vugt, JJFA, Geiger, JT, Shankaracharya, Smith, BN, Marangi, G, Topp, SD, Abramzon, Y, Kenna, A, Mora, G, Riva, N, La Bella, V, Conforti, FL, Borghero, G, Salvi, F, Logullo, FO, D'Alfonso, S, Corrado, L, Capasso, M, Ferrucci, L, Moreno, CDAM, Kamalakaran, S, Goldstein, DB, Gitler, AD, Abhyankar, A, Zody, MC, Kaye, J, LeNail, A, Fraenkel, E, Svendsen, CN, Van Eyk, JE, Berry, JD, Miller, TM, Kolb, SJ, Cudkowicz, M, Benatar, M, Rampersaud, E, Wu, G, Wuu, J, SLAGEN Consortium, Verde, F, Tiloca, C, Comi, GP, French ALS Consortium, Corcia, P, Laaksovirta, H, Myllykangas, L, Jansson, L, Valori, M, Johnson, JO, Arepalli, S, Sapp, PC, McKenna-Yasek, D, Polak, M, Asress, S, Al-Sarraj, S, Troakes, C, de Belleroche, J, Baas, F, Ten Asbroek, ALMA, Floeter, MK, Ravits, JM, Kirby, J, Pioro, EP, Pamphlett, R, Broach, J, Dunckley, TL, Brady, CB, Le Ber, I, Mouzat, K, Heiman-Patterson, TD, Van Den Bosch, L, Strom, TM, Shatunov, A, Van Eijk, KR, Moisse, M, Van Es, MA, Van Blitterswijk, M, Mora, JS, Turner, MR, Talbot, K, Fifita, JA, Blair, IP, Rouleau, GA, Esteban-Pérez, J, Rogaeva, E, Rothstein, JD, Cooper-Knock, J, Goutman, SA, Van Damme, P, Robberecht, W, Sabatelli, M, Lunetta, C, Weishaupt, JH, Chiò, A, Shaw, CE, Traynor, BJ

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Genome-wide Analyses Identify KIF5A as a Novel ALS Gene von Nicolas, A., Kenna, K.P., Chia, R., Dominov, J.A., Kenna, B.J., Nalls, M.A., Keagle, P., Rheenen, W. van, Murphy, N.A., Pliner, H.A., Topp, S.D., Mora, G., Calvo, A., Mazzini, L., Riva, N., Mandrioli, J., Bella, V. la, Conforti, F.L., Borghero, G., Salvi, F., Corrado, L., Ferrucci, L., Kamalakaran, S., Musunuri, R.L., Abhyankar, A., Eyk, J.E. van, Berry, J.D., Miller, T.M., Baxi, E., Taylor, J.P., Rampersaud, E., Wu, G., Verde, F., Fogh, I., Tiloca, C., Soraru, G., Cereda, C., Myllykangas, L., Jansson, L., Ealing, J., Hamdalla, H., Rollinson, S., Pickering-Brown, S., Sidle, K.C., Asress, S., Al-Sarraj, S., King, A., Belleroche, J. de, Hernandez, D.G., Ding, J.H., Floeter, M.K., Landi, F., Bowser, R., Ravits, J.M., MacGowan, D.J.L., Kirby, J., Pamphlett, R., Broach, J., Gerhard, G., Brady, C.B., Lumbroso, S., Heiman-Patterson, T.D., Kamel, F., Baloh, R.H., Strom, T.M., Meitinger, T., Eijk, K.R. van, Moisse, M., McLaughlin, R.L., Es, M.A. van, Weber, M., Boylan, K.B., Mora, J.S., Shaw, P.J., Turner, M.R., Talbot, K., Hardiman, O., Nicholson, G.A., Blair, I.P., Rouleau, G.A., Esteban-Perez, J., Garcia-Redondo, A., Zinman, L., Ostrow, L.W., Simmons, Z., Ratti, A., Fratta, P., Sabatelli, M., Lunetta, C., Weishaupt, J.H., Camu, W., Brown, R.H., Berg, L.H. van den, Veldink, J.H., Glass, J.D., Silani, V., Chio, A., Shaw, C.E., Traynor, B.J., Landers, J.E.

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CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1 von Bartkowiak, Bartlomiej, Liu, Pengda, Phatnani, Hemali P, Fuda, Nicholas J, Cooper, Jeffrey J, Price, David H, Adelman, Karen, Lis, John T, Greenleaf, Arno L

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Genome-wide Analyses Identify KIF5A as a Novel ALS Gene von Kenna, Kevin P., Chia, Ruth, Dominov, Janice A., Nalls, Mike A., van Vugt, Joke J.F.A., Simone, Isabella, Caredda, Carla, Milia, Antonio, Floris, Gianluca, Caponnetto, Claudia, Mandich, Paola, Mora, Gabriele, Sideri, Riccardo, Penco, Silvana, Mandrioli, Jessica, Trojsi, Francesca, Ticca, Anna, Ortu, Enzo, Pugliatti, Maura, Benigni, Michele, Brunetti, Maura, Marrali, Giuseppe, Riva, Nilo, Conforti, Francesca L., Messina, Sonia, D’Alfonso, Sandra, Baloh, Robert H., Penny, Michelle, Moreno, Cristiane de Araujo Martins, Chung, Wendy K., Cirulli, Elizabeth T., Harris, Tim, Krueger, Brian J., Lasseigne, Brittany N., McKenna-Yasek, Diane, Myers, Richard M., Pulst, Stefan M., Raphael, Alya R., Rouleau, Guy A., Sapp, Peter C., Waite, Lindsay L., Wang, Quanli, Ostrow, Lyle W., Baas, Frank, Zaitlen, Noah, Hornstein, Eran, Patsopoulos, Nikolaos A., Kaye, Julia, Wyman, Stacia, LeNail, Alexander, Baxi, Emily, LeNail, Alex, Benatar, Michael, Hussain, Sumaira, Swenson, Andrea, Jackson, Carlayne, So, Yuen, Wuu, Joanne, Silani, Vincenzo, Fogh, Isabella, Cereda, Cristina, Ceroni, Mauro, Mazzini, Letizia, Maderna, Luca, Sorarù, Gianni, Bernard, Emilien, Laaksovirta, Hannu, McKenna-Yasek, Diane, Asress, Seneshaw, Al-Sarraj, Safa, Scholz, Sonja W., MacGowan, Daniel J.L., Kirby, Janine, Pioro, Erik P., Pamphlett, Roger, Dunckley, Travis L., Troncoso, Juan C., Moisse, Matthieu, Drory, Vivian E., Turner, Martin R., Blair, Ian P., de Carvalho, Mamede, Hide, Winston, Glass, Jonathan, Mill, Jonathan, Newhouse, Stephen, Pulit, Sara, Robberecht, Wim, Shaw, Pamela, van den Berg, Leonard, Williams, Kelly L., Zatz, Mayana, Rothstein, Jeffrey D., Simmons, Zachary, Van Damme, Philip, Sabatelli, Mario, Trojanowski, John Q., Brown, Robert H., Veldink, Jan H., Tienari, Pentti

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TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A von Brown, Anna-Leigh, Wilkins, Oscar G., Keuss, Matthew J., Hill, Sarah E., Zanovello, Matteo, Lee, Weaverly Colleen, Bampton, Alexander, Lee, Flora C. Y., Masino, Laura, Qi, Yue A., Bryce-Smith, Sam, Gatt, Ariana, Hallegger, Martina, Fagegaltier, Delphine, Phatnani, Hemali, Newcombe, Jia, Gustavsson, Emil K., Seddighi, Sahba, Reyes, Joel F., Coon, Steven L., Ramos, Daniel, Schiavo, Giampietro, Fisher, Elizabeth M. C., Raj, Towfique, Secrier, Maria, Lashley, Tammaryn, Ule, Jernej, Buratti, Emanuele, Humphrey, Jack, Ward, Michael E., Fratta, Pietro

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