Ectopic upregulation of membrane-bound IL6R drives vascular remodeling in pulmonary arterial hypertension von Tamura, Yuichi, Phan, Carole, Tu, Ly, Le Hiress, Morane, Thuillet, Raphaël, Jutant, Etienne-Marie, Fadel, Elie, Savale, Laurent, Huertas, Alice, Humbert, Marc, Guignabert, Christophe

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Selective BMP-9 Inhibition Partially Protects Against Experimental Pulmonary Hypertension von Tu, Ly, Desroches-Castan, Agnès, Mallet, Christine, Guyon, Laurent, Cumont, Amélie, Phan, Carole, Robert, Florian, Thuillet, Raphaël, Bordenave, Jennifer, Sekine, Ayumi, Huertas, Alice, Ritvos, Olli, Savale, Laurent, Feige, Jean-Jacques, Humbert, Marc, Bailly, Sabine, Guignabert, Christophe

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Proinflammatory Signature of the Dysfunctional Endothelium in Pulmonary Hypertension. Role of the Macrophage Migration Inhibitory Factor/CD74 Complex von Le Hiress, Morane, Tu, Ly, Ricard, Nicolas, Phan, Carole, Thuillet, Raphaël, Fadel, Elie, Dorfmüller, Peter, Montani, David, de Man, Frances, Humbert, Marc, Huertas, Alice, Guignabert, Christophe

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Neutralization of CXCL12 attenuates established pulmonary hypertension in rats von Bordenave, Jennifer, Thuillet, Raphaël, Tu, Ly, Phan, Carole, Cumont, Amélie, Marsol, Claire, Huertas, Alice, Savale, Laurent, Hibert, Marcel, Galzi, Jean-Luc, Bonnet, Dominique, Humbert, Marc, Frossard, Nelly, Guignabert, Christophe

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Increased Pericyte Coverage Mediated by Endothelial-Derived Fibroblast Growth Factor-2 and Interleukin-6 Is a Source of Smooth Muscle–Like Cells in Pulmonary Hypertension von Ricard, Nicolas, Tu, Ly, Le Hiress, Morane, Huertas, Alice, Phan, Carole, Thuillet, Raphaël, Sattler, Caroline, Fadel, Elie, Seferian, Andrei, Montani, David, Dorfmüller, Peter, Humbert, Marc, Guignabert, Christophe

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Serum and pulmonary uric acid in pulmonary arterial hypertension von Savale, Laurent, Akagi, Satoshi, Tu, Ly, Cumont, Amelie, Thuillet, Raphael, Phan, Carole, Le Vely, Benjamin, Berrebeh, Nihel, Huertas, Alice, Jais, Xavier, Cottin, Vincent, Chaouat, Ari, Tromeur, Cecile, Boucly, Athenais, Jutant, Etienne Marie, Mercier, Olaf, Fadel, Elie, Montani, David, Sitbon, Olivier, Humbert, Marc, Tamura, Yuichi, Guignabert, Christophe

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Dasatinib increases endothelial permeability leading to pleural effusion von Phan, Carole, Jutant, Etienne-Marie, Tu, Ly, Thuillet, Raphaël, Seferian, Andrei, Montani, David, Huertas, Alice, Bezu, Jan van, Breijer, Fabian, Vonk Noordegraaf, Anton, Humbert, Marc, Aman, Jurjan, Guignabert, Christophe

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Regulatory T Cell Dysfunction in Idiopathic, Heritable and Connective Tissue-Associated Pulmonary Arterial Hypertension von Huertas, Alice, MD, PhD, Phan, Carole, MS, Bordenave, Jennifer, MS, Tu, Ly, PhD, Thuillet, Raphaël, BS, Le Hiress, Morane, PhD, Avouac, Jérôme, MD, PhD, Tamura, Yuichi, MD, PhD, Allanore, Yannick, MD, PhD, Jovan, Roland, MD, Sitbon, Olivier, MD, PhD, Guignabert, Christophe, PhD, Humbert, Marc, MD, PhD

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Role of Nerve Growth Factor in Development and Persistence of Experimental Pulmonary Hypertension von Freund-Michel, Véronique, Cardoso Dos Santos, Marcelina, Guignabert, Christophe, Montani, David, Phan, Carole, Coste, Florence, Tu, Ly, Dubois, Mathilde, Girerd, Barbara, Courtois, Arnaud, Humbert, Marc, Savineau, Jean-Pierre, Marthan, Roger, Muller, Bernard

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Switching-Off Adora2b in Vascular Smooth Muscle Cells Halts the Development of Pulmonary Hypertension von Mertens, Tinne C J, Hanmandlu, Ankit, Tu, Ly, Phan, Carole, Collum, Scott D, Chen, Ning-Yuan, Weng, Tingting, Davies, Jonathan, Liu, Chen, Eltzschig, Holger K, Jyothula, Soma S K, Rajagopal, Keshava, Xia, Yang, Guha, Ashrith, Bruckner, Brian A, Blackburn, Michael R, Guignabert, Christophe, Karmouty-Quintana, Harry

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Self-organized tissue mechanics underlie embryonic regulation von Caldarelli, Paolo, Chamolly, Alexander, Villedieu, Aurélien, Alegria-Prévot, Olinda, Phan, Carole, Gros, Jerome, Corson, Francis

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Dasatinib induces lung vascular toxicity and predisposes to pulmonary hypertension von Guignabert, Christophe, Phan, Carole, Seferian, Andrei, Huertas, Alice, Tu, Ly, Thuillet, Raphaël, Sattler, Caroline, Le Hiress, Morane, Tamura, Yuichi, Jutant, Etienne-Marie, Chaumais, Marie-Camille, Bouchet, Stéphane, Manéglier, Benjamin, Molimard, Mathieu, Rousselot, Philippe, Sitbon, Olivier, Simonneau, Gérald, Montani, David, Humbert, Marc

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Leptin signalling system as a target for pulmonary arterial hypertension therapy von Huertas, Alice, Tu, Ly, Thuillet, Raphaël, Le Hiress, Morane, Phan, Carole, Ricard, Nicolas, Nadaud, Sophie, Fadel, Elie, Humbert, Marc, Guignabert, Christophe

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Loss of cAbl Tyrosine Kinase in Pulmonary Arterial Hypertension Causes Dysfunction of Vascular Endothelial Cells von Le Vely, Benjamin, Phan, Carole, Berrebeh, Nihel, Thuillet, Raphaël, Ottaviani, Mina, Chelgham, Mustapha Kamel, Chaumais, Marie-Camille, Amazit, Larbi, Humbert, Marc, Huertas, Alice, Guignabert, Christophe, Tu, Ly

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Loss of cAbl Tyrosine Kinase in Pulmonary Arterial Hypertension Causes Dysfunction of Vascular Endothelial Cells von Le Vely, Benjamin, Phan, Carole, Berrebeh, Nihel, Thuillet, Raphaël, Ottaviani, Mina, Chelgham, Mustapha Kamel, Chaumais, Marie-Camille, Amazit, Larbi, Humbert, Marc, Huertas, Alice, Guignabert, Christophe, Tu, Ly

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Design, Synthesis, and Biological Activity of New N‑(Phenylmethyl)-benzoxazol-2-thiones as Macrophage Migration Inhibitory Factor (MIF) Antagonists: Efficacies in Experimental Pulm... von Le Hiress, Morane, Akagah, Bernardin, Bernadat, Guillaume, Tu, Ly, Thuillet, Raphaël, Huertas, Alice, Phan, Carole, Fadel, Elie, Simonneau, Gérald, Humbert, Marc, Jalce, Gaël, Guignabert, Christophe

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Therapeutic effect of pirfenidone in the sugen/hypoxia rat model of severe pulmonary hypertension von Poble, Paul-Benoit, Phan, Carole, Quatremare, Timothée, Bordenave, Jennifer, Thuillet, Raphaël, Cumont, Amélie, Huertas, Alice, Tu, Ly, Dorfmüller, Peter, Humbert, Marc, Ghigna, Maria-Rosa, Savale, Laurent, Guignabert, Christophe

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Connexin-43 is a promising target for pulmonary hypertension due to hypoxaemic lung disease von Bouvard, Claire, Genet, Nafiisha, Phan, Carole, Rode, Baptiste, Thuillet, Raphael, Tu, Ly, Robillard, Paul, Campagnac, Marilyne, Soleti, Raffaella, De La Roque, Eric Dumas, Delcambre, Frederic, Cronier, Laurent, Parpaite, Thibaud, Maurat, Elise, Berger, Patrick, Savineau, Jean-Pierre, Marthan, Roger, Guignabert, Christophe, Freund-Michel, Veronique, Guibert, Christelle

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IL6R is the key therapeutical target in pulmonary arterial hypertension von Tu, Ly, Phan, Carole, Humbert, Marc, Guignabert, Christophe

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Functional interaction between PDGFβ and GluN2B-containing NMDA receptors in smooth muscle cell proliferation and migration in pulmonary arterial hypertension von Quatredeniers, Marceau, Nakhleh, Morad K, Dumas, Sébastien J, Courboulin, Audrey, Vinhas, Maria C, Antigny, Fabrice, Phan, Carole, Guignabert, Christophe, Bendifallah, Imane, Vocelle, Matthieu, Fadel, Elie, Dorfmüller, Peter, Humbert, Marc, Cohen-Kaminsky, Sylvia

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