CHMP2A regulates tumor sensitivity to natural killer cell-mediated cytotoxicity von Bernareggi, Davide, Xie, Qi, Prager, Briana C., Yun, Jiyoung, Cruz, Luisjesus S., Pham, Timothy V., Kim, William, Lee, Xiqing, Coffey, Michael, Zalfa, Cristina, Azmoon, Pardis, Zhu, Huang, Tamayo, Pablo, Rich, Jeremy N., Kaufman, Dan S.

Volltext

Role of ultraviolet mutational signature versus tumor mutation burden in predicting response to immunotherapy von Pham, Timothy V., Boichard, Amélie, Goodman, Aaron, Riviere, Paul, Yeerna, Huwate, Tamayo, Pablo, Kurzrock, Razelle

Volltext

APOBEC-related mutagenesis and neo-peptide hydrophobicity: implications for response to immunotherapy von Boichard, Amélie, Pham, Timothy V., Yeerna, Huwate, Goodman, Aaron, Tamayo, Pablo, Lippman, Scott, Frampton, Garrett M., Tsigelny, Igor F., Kurzrock, Razelle

Volltext

Targeting macrophage Syk enhances responses to immune checkpoint blockade and radiotherapy in high-risk neuroblastoma von Rohila, Deepak, Park, In Hwan, Pham, Timothy V, Jones, Riley, Tapia, Elisabette, Liu, Kevin X, Tamayo, Pablo, Yu, Alice, Sharabi, Andrew B, Joshi, Shweta

Volltext

Intra-patient stability of tumor mutational burden from tissue biopsies at different time points in advanced cancers von Pham, Timothy V., Goodman, Aaron M., Sivakumar, Smruthy, Frampton, Garrett, Kurzrock, Razelle

Volltext

Human induced pluripotent stem cell‐derived macrophages ameliorate liver fibrosis von Pouyanfard, Somayeh, Meshgin, Nairika, Cruz, Luisjesus S., Diggle, Karin, Hashemi, Hamidreza, Pham, Timothy V., Fierro, Manuel, Tamayo, Pablo, Fanjul, Andrea, Kisseleva, Tatiana, Kaufman, Dan S.

Volltext

Syk Inhibition Reprograms Tumor-Associated Macrophages and Overcomes Gemcitabine-Induced Immunosuppression in Pancreatic Ductal Adenocarcinoma von Rohila, Deepak, Park, In Hwan, Pham, Timothy V, Weitz, Jonathan, Hurtado de Mendoza, Tatiana, Madheswaran, Suresh, Ishfaq, Mehreen, Beaman, Cooper, Tapia, Elisabette, Sun, Siming, Patel, Jay, Tamayo, Pablo, Lowy, Andrew M, Joshi, Shweta

Volltext

SF2523: Dual PI3K/BRD4 Inhibitor Blocks Tumor Immunosuppression and Promotes Adaptive Immune Responses in Cancer von Joshi, Shweta, Singh, Alok R, Liu, Kevin X, Pham, Timothy V, Zulcic, Muamera, Skola, Dylan, Chun, Hyun Bae, Glass, Christopher K, Morales, Guillermo A, Garlich, Joseph R, Durden, Donald L

Volltext

Macrophage Syk-PI3K gamma Inhibits Antitumor Immunity: SRX3207, a Novel Dual Syk-PI3K Inhibitory Chemotype Relieves Tumor Immunosuppression von Joshi, Shweta, Liu, Kevin X., Zulcic, Muamera, Singh, Alok R., Skola, Dylan, Glass, Christopher K., Sanders, P. Dominick, Sharabi, Andrew B., Pham, Timothy, Tamayo, Pablo, Shiang, Daniel, Dinh, Huy Q., Hedrick, Catherine C., Morales, Guillermo A., Garlich, Joseph R., Durden, Donald L.

Volltext

Abstract 2298: Understanding tumor biology complexity in the advanced cancer setting: PreciGENE® platform predictions correlate with exceptional responses to cancer treatment von Boichard, Amelie, Pham, Timothy V., Richard, Stephane B., Kurzrock, Razelle

Volltext

Macrophage Syk-PI3Kγ inhibits anti-tumor immunity: SRX3207, a novel dual Syk-PI3K inhibitory chemotype relieves tumor immunosuppression von Joshi, Shweta, Liu, Kevin X., Zulcic, Muamera, Singh, Alok R., Skola, Dylan, Glass, Christopher K., Sanders, P. Dominick, Sharabi, Andrew B., Pham, Timothy V., Tamayo, Pablo, Shiang, Daniel, Dinh, Huy Q., Hedrick, Catherine C., Morales, Guillermo A., Garlich, Joseph R., Durden, Donald L.

Volltext

Additional file 2 of Intra-patient stability of tumor mutational burden from tissue biopsies at different time points in advanced cancers von Pham, Timothy V., Goodman, Aaron M., Sivakumar, Smruthy, Frampton, Garrett, Kurzrock, Razelle

Volltext bestellen

Elicitation of Potent Neutralizing Antibody Responses by Designed Protein Nanoparticle Vaccines for SARS-CoV-2 von Walls, Alexandra C., Fiala, Brooke, Schäfer, Alexandra, Wrenn, Samuel, Pham, Minh N., Murphy, Michael, Tse, Longping V., Shehata, Laila, O’Connor, Megan A., Chen, Chengbo, Navarro, Mary Jane, Miranda, Marcos C., Pettie, Deleah, Ravichandran, Rashmi, Kraft, John C., Ogohara, Cassandra, Palser, Anne, Chalk, Sara, Lee, E-Chiang, Guerriero, Kathryn, Kepl, Elizabeth, Chow, Cameron M., Sydeman, Claire, Hodge, Edgar A., Brown, Brieann, Fuller, Jim T., Dinnon, Kenneth H., Gralinski, Lisa E., Leist, Sarah R., Gully, Kendra L., Lewis, Thomas B., Guttman, Miklos, Chu, Helen Y., Lee, Kelly K., Fuller, Deborah H., Baric, Ralph S., Kellam, Paul, Carter, Lauren, Pepper, Marion, Sheahan, Timothy P., Veesler, David, King, Neil P.

Volltext

Identification of AV-1451 as a Weak, Nonselective Inhibitor of Monoamine Oxidase von Drake, Lindsey R, Pham, Jonathan M, Desmond, Timothy J, Mossine, Andrew V, Lee, So Jeong, Kilbourn, Michael R, Koeppe, Robert A, Brooks, Allen F, Scott, Peter J.H

Volltext

All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs von Schork, Andrew J, Thompson, Wesley K, Pham, Phillip, Torkamani, Ali, Roddey, J Cooper, Sullivan, Patrick F, Kelsoe, John R, O'Donovan, Michael C, Furberg, Helena, Schork, Nicholas J, Andreassen, Ole A, Dale, Anders M

Volltext

Multispectral Nanoparticle Tracking Analysis for the Real-Time and Label-Free Characterization of Amyloid‑β Self-Assembly In Vitro von Moore, Colman, Wing, Ryan, Pham, Timothy, Jokerst, Jesse V

Volltext

GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures von Styrkarsdottir, Unnur, Stefansson, Olafur A., Gunnarsdottir, Kristbjorg, Thorleifsson, Gudmar, Lund, Sigrun H., Stefansdottir, Lilja, Juliusson, Kristinn, Agustsdottir, Arna B., Zink, Florian, Halldorsson, Gisli H., Ivarsdottir, Erna V., Benonisdottir, Stefania, Jonsson, Hakon, Gylfason, Arnaldur, Norland, Kristjan, Trajanoska, Katerina, Boer, Cindy G., Southam, Lorraine, Leung, Jason C. S., Tang, Nelson L. S., Kwok, Timothy C. Y., Lee, Jenny S. W., Ho, Suzanne C., Byrjalsen, Inger, Center, Jacqueline R., Lee, Seung Hun, Koh, Jung-Min, Lohmander, L. Stefan, Ho-Pham, Lan T., Nguyen, Tuan V., Eisman, John A., Woo, Jean, Leung, Ping-C., Loughlin, John, Zeggini, Eleftheria, Christiansen, Claus, Rivadeneira, Fernando, van Meurs, Joyce, Uitterlinden, Andre G., Mogensen, Brynjolfur, Jonsson, Helgi, Ingvarsson, Thorvaldur, Sigurdsson, Gunnar, Benediktsson, Rafn, Sulem, Patrick, Jonsdottir, Ingileif, Masson, Gisli, Holm, Hilma, Norddahl, Gudmundur L., Thorsteinsdottir, Unnur, Gudbjartsson, Daniel F., Stefansson, Kari

Volltext

Jagged2 targeting in lung cancer activates anti-tumor immunity via Notch-induced functional reprogramming of tumor-associated macrophages von Mandula, Jay K., Sierra-Mondragon, Rosa A., Jimenez, Rachel V., Chang, Darwin, Mohamed, Eslam, Chang, Shiun, Vazquez-Martinez, Julio A., Cao, Yu, Anadon, Carmen M., Lee, Sae Bom, Das, Satyajit, Rocha-Munguba, Léo, Pham, Vincent M., Li, Roger, Tarhini, Ahmad A., Furqan, Muhammad, Dalton, William, Churchman, Michelle, Moran-Segura, Carlos M., Nguyen, Jonathan, Perez, Bradford, Kojetin, Douglas J., Obermayer, Alyssa, Yu, Xiaoqing, Chen, Ann, Shaw, Timothy I., Conejo-Garcia, Jose R., Rodriguez, Paulo C.

Volltext

Structure of the insulin receptor ectodomain reveals a folded-over conformation von Lawrence, Michael C, Ward, Colin W, McKern, Neil M, Streltsov, Victor A, Lou, Mei-Zhen, Adams, Timothy E, Lovrecz, George O, Elleman, Thomas C, Richards, Kim M, Bentley, John D, Pilling, Patricia A, Hoyne, Peter A, Cartledge, Kellie A, Pham, Tam M, Lewis, Jennifer L, Sankovich, Sonia E, Stoichevska, Violet, Da Silva, Elizabeth, Robinson, Christine P, Frenkel, Maurice J, Sparrow, Lindsay G, Fernley, Ross T, Epa, V. Chandana

Volltext

Long non-coding RNA PCAT19 safeguards DNA in quiescent endothelial cells by preventing uncontrolled phosphorylation of RPA2 von Oo, James A., Pálfi, Katalin, Warwick, Timothy, Wittig, Ilka, Prieto-Garcia, Cristian, Matkovic, Vigor, Tomašković, Ines, Boos, Frederike, Izquierdo Ponce, Judit, Teichmann, Tom, Petriukov, Kirill, Haydar, Shaza, Maegdefessel, Lars, Wu, Zhiyuan, Pham, Minh Duc, Krishnan, Jaya, Baker, Andrew H., Günther, Stefan, Ulrich, Helle D., Dikic, Ivan, Leisegang, Matthias S., Brandes, Ralf P.

Volltext