Tumor necrosis factor signaling von Wajant, H, Pfizenmaier, K, Scheurich, P

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Enforced covalent trimerization increases the activity of the TNF ligand family members TRAIL and CD95L von Berg, D, Lehne, M, Müller, N, Siegmund, D, Münkel, S, Sebald, W, Pfizenmaier, K, Wajant, H

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An XBP-1 dependent bottle-neck in production of IgG subtype antibodies in chemically defined serum-free Chinese hamster ovary (CHO) fed-batch processes von Becker, Eric, Florin, Lore, Pfizenmaier, Klaus, Kaufmann, Hitto

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TNF-related apoptosis inducing ligand (TRAIL) and its receptors in tumor surveillance and cancer therapy von Wajant, H, Pfizenmaier, K, Scheurich, P

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Superior antitumoral activity of dimerized targeted single-chain TRAIL fusion proteins under retention of tumor selectivity von Siegemund, M, Pollak, N, Seifert, O, Wahl, K, Hanak, K, Vogel, A, Nussler, A K, Göttsch, D, Münkel, S, Bantel, H, Kontermann, R E, Pfizenmaier, K

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OMTX705, a powerful stroma-targeting ADC to treat invasive tumors with low response to immunotherapeutic anti-PD-1 treatments von Fabre, M., Ferrer, C., Dominguez-Hormaetxe, S., Kontermann, R., Pfizenmaier, K., Seifert, O., López-Casas, P.P., Abbas, M., Richter, W., Simon, L., Hidalgo, M.

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Neuroprotective and neurodegenerative effects of the chronic expression of tumor necrosis factor α in the nigrostriatal dopaminergic circuit of adult mice von Chertoff, M., Di Paolo, N., Schoeneberg, A., Depino, A., Ferrari, C., Wurst, W., Pfizenmaier, K., Eisel, U., Pitossi, F.

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Potent antitumoral activity of TRAIL through generation of tumor-targeted single-chain fusion proteins von Schneider, B, Münkel, S, Krippner-Heidenreich, A, Grunwald, I, Wels, W S, Wajant, H, Pfizenmaier, K, Gerspach, J

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PKC zeta is a molecular switch in signal transduction of TNF‐alpha, bifunctionally regulated by ceramide and arachidonic acid von Müller, G., Ayoub, M., Storz, P., Rennecke, J., Fabbro, D., Pfizenmaier, K.

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PKCu is a novel, atypical member of the protein kinase C family von JOHANNES, F.-J, PRESTLE, J, EIS, S, OBERHAGEMANN, P, PIFZENMAIER, K

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Activation of CD95L fusion protein prodrugs by tumor-associated proteases von Watermann, I, Gerspach, J, Lehne, M, Seufert, J, Schneider, B, Pfizenmaier, K, Wajant, H

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Protein kinase D regulates vesicular transport by phosphorylating and activating phosphatidylinositol-4 kinase IIIβ at the Golgi complex von Hausser, Angelika, Pfizenmaier, Klaus, Storz, Peter, Märtens, Susanne, Link, Gisela, Toker, Alex

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Protein Kinase C μ Is Regulated by the Multifunctional Chaperon Protein p32 von Storz, Peter, Hausser, Angelika, Link, Gisela, Dedio, Jürgen, Ghebrehiwet, Berhane, Pfizenmaier, Klaus, Johannes, Franz-Josef

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An anti-TNFR1 scFv-HSA fusion protein as selective antagonist of TNF action von Berger, V., Richter, F., Zettlitz, K., Unverdorben, F., Scheurich, P., Herrmann, A., Pfizenmaier, K., Kontermann, R. E.

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Tumor necrosis factor (TNF)-mediated neuroprotection against glutamate-induced excitotoxicity is enhanced by N-methyl-D-aspartate receptor activation. Essential role of a TNF recep... von Marchetti, Lara, Klein, Matthias, Schlett, Katalin, Pfizenmaier, Klaus, Eisel, Ulrich L M

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Immunoregulatory activity of recombinant human tumor necrosis factor (TNF)-alpha: induction of TNF receptors on human T cells and TNF-alpha- mediated enhancement of T cell response... von Scheurich, P, Thoma, B, Ucer, U, Pfizenmaier, K

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Neurodegenerative and Neuroprotective Effects of Tumor Necrosis Factor (TNF) in Retinal Ischemia: Opposite Roles of TNF Receptor 1 and TNF Receptor 2 von Fontaine, Valerie, Mohand-Said, Saddek, Hanoteau, Noelle, Fuchs, Celine, Pfizenmaier, Klaus, Eisel, Ulrich

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Construction of a bispecific single chain antibody for recruitment of cytotoxic T cells to the tumour stroma associated antigen fibroblast activation protein von Wüest, Thomas, Moosmayer, Dieter, Pfizenmaier, Klaus

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Protein Kinase C μ Is Located at the Golgi Compartment von Prestle, Jürgen, Pfizenmaier, Klaus, Brenner, Joachim, Johannes, Franz-Josef

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TNF receptors TR60 and TR80 can mediate apoptosis via induction of distinct signal pathways von Grell, M, Zimmermann, G, Hulser, D, Pfizenmaier, K, Scheurich, P

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