Suppression of proinvasive RGS4 by mTOR inhibition optimizes glioma treatment von Weiler, M, Pfenning, P-N, Thiepold, A-L, Blaes, J, Jestaedt, L, Gronych, J, Dittmann, L M, Berger, B, Jugold, M, Kosch, M, Combs, S E, von Deimling, A, Weller, M, Bendszus, M, Platten, M, Wick, W

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P54 Irradiation-enhanced mammalian target of rapamycin (mTOR)-targeted glioblastoma therapy with CCI-779 (temsirolimus) von Weiler, M, Pfenning, P.-N, Thiepold, A.-L, Jestaedt, L, Berger, B, Bendszus, M, Wick, W

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Defective p53 antiangiogenic signaling in glioblastoma von Berger, Benjamin, Capper, David, Lemke, Dieter, Pfenning, Philipp-Niclas, Platten, Michael, Weller, Michael, von Deimling, Andreas, Wick, Wolfgang, Weiler, Markus

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mTOR target NDRG1 confers MGMT-dependent resistance to alkylating chemotherapy von Weiler, M, Blaes, J, Pusch, S, Sahm, F, Czabanka, M, Luger, S, Bunse, L, Solecki, G, Eichwald, V, Jugold, M, Hodecker, S, Osswald, M, Meisner, C, Hielscher, T, Rübmann, P, Pfenning, P N, Ronellenfitsch, M, Kempf, T, Schnölzer, M, Abdollahi, A, Lang, F, Bendszus, M, von Deimling, A, Winkler, F, Weller, M, Vajkoczy, P, Platten, M, Wick, W

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Suppression of proinvasive RGS4 by mTOR inhibition optimizes glioma treatment von Weiler, M, Pfenning, P N, Thiepold, A L, Blaes, J, Jestaedt, L, Gronych, J, Dittmann, L M, Berger, B, Jugold, M, Kosch, M, Combs, S E, von Deimling, A, Weller, M, Bendszus, M, Platten, M, Wick, W

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Costimulatory protein 4IgB7H3 drives the malignant phenotype of glioblastoma by mediating immune escape and invasiveness von Lemke, D, Pfenning, P N, Sahm, F, Klein, A C, Kempf, T, Warnken, U, Schnölzer, M, Tudoran, R, Weller, M, Platten, M, Wick, W

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Defective p53 antiangiogenic signaling in glioblastoma von Berger, B, Capper, D, Lemke, D, Pfenning, P N, Platten, M, Weller, M, von Deimling, A, Wick, W, Weiler, M

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ANGIOGENESIS AND INVASION von Hu, Y.-L., De Lay, M., Rose, S. D., Carbonell, W. S., Aghi, M. K., Paquette, J., Tokuyasu, T., Tsao, S., Chaumeil, M., Ronen, S., Matlaf, L. A., Soroceanu, L., Cobbs, C., Matlaf, L., Harkins, L., Garzon-Muvdi, T., Rhys, C. a., Smith, C., Kim, D.-H., Kone, L., Farber, H., An, S., Levchenko, A., Quinones-Hinojosa, A., Lemke, D., Pfenning, P.-N., Sahm, F., Klein, A.-C., Kempf, T., Schnolzer, M., Platten, M., Wick, W., Smith, S. J., Rahman, R., Rahman, C., Barrow, J., Macarthur, D., Rose, F., Grundy, R. G., Kaley, T. J., Huse, J., Karimi, S., Rosenblum, M., Omuro, A., DeAngelis, L. M., de Groot, J. F., Kong, L.-Y., Wei, J., Wang, T., Piao, Y., Liang, J., Fuller, G. N., Qiao, W., Heimberger, A. B., Jhaveri, N., Cho, H., Torres, S., Wang, W., Schonthal, A., Petasis, N., Louie, S. G., Hofman, F., Chen, T. C., Yamada, R., Sumual, S., Buljan, V., Bennett, M. R., McDonald, K. L., Weiler, M., Thiepold, A.-L., Jestaedt, L., Gronych, J., Dittmann, L. M., Jugold, M., Kosch, M., Combs, S. E., von Deimling, A., Weller, M., Bendszus, M., Kwiatkowska, A., Paulino, V., Tran, N. L., Symons, M., Stockham, A. L., Borden, E., Peereboom, D., Hu, Y., Chaturbedi, A., Hamamura, M., Mark, E., Zhou, Y.-H., Abbadi, S., Guerrero-Cazares, H., Pistollato, F., Smith, C. L., Ruff, W., Puppa, A. D., Basso, G., Monje, M., Freret, M. E.

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A comparative genomics multitool for scientific discovery and conservation von Genereux, Diane P., Serres, Aitor, Armstrong, Joel, Johnson, Jeremy, Marinescu, Voichita D., Muren, Eva, Juan, David, Bejerano, Gill, Casewell, Nicholas R., Chemnick, Leona G., Damas, Joana, Di Palma, Federica, Diekhans, Mark, Fiddes, Ian T., Garber, Manuel, Gladyshev, Vadim N., Goodman, Linda, Haerty, Wilfried, Houck, Marlys L., Hubley, Robert, Kivioja, Teemu, Koepfli, Klaus-Peter, Kuderna, Lukas F. K., Lander, Eric S., Meadows, Jennifer R. S., Murphy, William J., Nash, Will, Noh, Hyun Ji, Nweeia, Martin, Pfenning, Andreas R., Pollard, Katherine S., Ray, David A., Shapiro, Beth, Smit, Arian F. A., Springer, Mark S., Steiner, Cynthia C., Swofford, Ross, Taipale, Jussi, Teeling, Emma C., Turner-Maier, Jason, Alfoldi, Jessica, Birren, Bruce, Ryder, Oliver A., Lewin, Harris A., Paten, Benedict, Marques-Bonet, Tomas, Lindblad-Toh, Kerstin, Karlsson, Elinor K.

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Spatial, transcriptomic, and epigenomic analyses link dorsal horn neurons to chronic pain genetic predisposition von Arokiaraj, Cynthia M., Leone, Michael J., Kleyman, Michael, Chamessian, Alexander, Noh, Myung-Chul, Phan, BaDoi N., Lopes, Bettega C., Corrigan, Kelly A., Cherupally, Vijay Kiran, Yeramosu, Deepika, Franusich, Michael E., Podder, Riya, Lele, Sumitra, Shiers, Stephanie, Kang, Byungsoo, Kennedy, Meaghan M., Chen, Viola, Chen, Ziheng, Mathys, Hansruedi, Dum, Richard P., Lewis, David A., Qadri, Yawar, Price, Theodore J., Pfenning, Andreas R., Seal, Rebecca P.

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Leveraging base-pair mammalian constraint to understand genetic variation and human disease von Sullivan, Patrick F, Meadows, Jennifer R S, Gazal, Steven, Phan, BaDoi N, Li, Xue, Genereux, Diane P, Dong, Michael X, Bianchi, Matteo, Andrews, Gregory, Sakthikumar, Sharadha, Nordin, Jessika, Roy, Ananya, Christmas, Matthew J, Marinescu, Voichita D, Wang, Chao, Wallerman, Ola, Xue, James, Yao, Shuyang, Sun, Quan, Szatkiewicz, Jin, Wen, Jia, Huckins, Laura M, Lawler, Alyssa, Keough, Kathleen C, Zheng, Zhili, Zeng, Jian, Wray, Naomi R, Li, Yun, Johnson, Jessica, Chen, Jiawen, Paten, Benedict, Reilly, Steven K, Hughes, Graham M, Weng, Zhiping, Pollard, Katherine S, Pfenning, Andreas R, Forsberg-Nilsson, Karin, Karlsson, Elinor K, Lindblad-Toh, Kerstin

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The genome of a songbird von Warren, Wesley C, Clayton, David F, Ellegren, Hans, Arnold, Arthur P, Hillier, LaDeana W, Künstner, Axel, Searle, Steve, White, Simon, Vilella, Albert J, Fairley, Susan, Heger, Andreas, Kong, Lesheng, Ponting, Chris P, Jarvis, Erich D, Mello, Claudio V, Minx, Pat, Lovell, Peter, Velho, Tarciso A. F, Ferris, Margaret, Balakrishnan, Christopher N, Sinha, Saurabh, Blatti, Charles, London, Sarah E, Li, Yun, Lin, Ya-Chi, George, Julia, Sweedler, Jonathan, Southey, Bruce, Gunaratne, Preethi, Watson, Michael, Nam, Kiwoong, Backström, Niclas, Smeds, Linnea, Nabholz, Benoit, Itoh, Yuichiro, Whitney, Osceola, Pfenning, Andreas R, Howard, Jason, Völker, Martin, Skinner, Bejamin M, Griffin, Darren K, Ye, Liang, McLaren, William M, Flicek, Paul, Quesada, Victor, Velasco, Gloria, Lopez-Otin, Carlos, Puente, Xose S, Olender, Tsviya, Lancet, Doron, Smit, Arian F. A, Hubley, Robert, Konkel, Miriam K, Walker, Jerilyn A, Batzer, Mark A, Gu, Wanjun, Pollock, David D, Chen, Lin, Cheng, Ze, Eichler, Evan E, Stapley, Jessica, Slate, Jon, Ekblom, Robert, Birkhead, Tim, Burke, Terry, Burt, David, Scharff, Constance, Adam, Iris, Richard, Hugues, Sultan, Marc, Soldatov, Alexey, Lehrach, Hans, Edwards, Scott V, Yang, Shiaw-Pyng, Li, XiaoChing, Graves, Tina, Fulton, Lucinda, Nelson, Joanne, Chinwalla, Asif, Hou, Shunfeng, Mardis, Elaine R, Wilson, Richard K

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Evolutionary constraint and innovation across hundreds of placental mammals von Christmas, Matthew J, Kaplow, Irene M, Genereux, Diane P, Dong, Michael X, Hughes, Graham M, Li, Xue, Sullivan, Patrick F, Hindle, Allyson G, Andrews, Gregory, Armstrong, Joel C, Bianchi, Matteo, Breit, Ana M, Diekhans, Mark, Fanter, Cornelia, Foley, Nicole M, Goodman, Daniel B, Goodman, Linda, Keough, Kathleen C, Kirilenko, Bogdan, Kowalczyk, Amanda, Lawless, Colleen, Lind, Abigail L, Meadows, Jennifer R S, Moreira, Lucas R, Redlich, Ruby W, Ryan, Louise, Swofford, Ross, Valenzuela, Alejandro, Wagner, Franziska, Wallerman, Ola, Brown, Ashley R, Damas, Joana, Fan, Kaili, Gatesy, John, Grimshaw, Jenna, Johnson, Jeremy, Kozyrev, Sergey V, Lawler, Alyssa J, Marinescu, Voichita D, Morrill, Kathleen M, Osmanski, Austin, Paulat, Nicole S, Phan, BaDoi N, Reilly, Steven K, Schäffer, Daniel E, Steiner, Cynthia, Supple, Megan A, Wilder, Aryn P, Wirthlin, Morgan E, Xue, James R, Birren, Bruce W, Gazal, Steven, Hubley, Robert M, Koepfli, Klaus-Peter, Marques-Bonet, Tomas, Meyer, Wynn K, Nweeia, Martin, Sabeti, Pardis C, Shapiro, Beth, Smit, Arian F A, Springer, Mark S, Teeling, Emma C, Weng, Zhiping, Hiller, Michael, Levesque, Danielle L, Lewin, Harris A, Murphy, William J, Navarro, Arcadi, Paten, Benedict, Pollard, Katherine S, Ray, David A, Ruf, Irina, Ryder, Oliver A, Pfenning, Andreas R, Lindblad-Toh, Kerstin, Karlsson, Elinor K

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Comparative genomics reveals insights into avian genome evolution and adaptation von Zhang, Guojie, Li, Cai, Li, Qiye, Li, Bo, Larkin, Denis M., Lee, Chul, Storz, Jay F., Antunes, Agostinho, Greenwold, Matthew J., Meredith, Robert W., Ödeen, Anders, Cui, Jie, Xu, Luohao, Wang, Zongji, Jin, Lijun, Zhang, Pei, Hu, Haofu, Yang, Wei, Hu, Jiang, Xiao, Jin, Yang, Zhikai, Liu, Yang, Xie, Qiaolin, Yu, Hao, Lian, Jinmin, Wen, Ping, Zhang, Fang, Li, Hui, Zeng, Yongli, Xiong, Zijun, Liu, Shiping, Zhou, Long, Huang, Zhiyong, An, Na, Wang, Jie, Zheng, Qiumei, Xiong, Yingqi, Wang, Guangbiao, Wang, Bo, Wang, Jingjing, Fan, Yu, da Fonseca, Rute R., Alfaro-Núñez, Alonzo, Schubert, Mikkel, Orlando, Ludovic, Mourier, Tobias, Howard, Jason T., Ganapathy, Ganeshkumar, Pfenning, Andreas, Whitney, Osceola, Rivas, Miriam V., Hara, Erina, Smith, Julia, Farré, Marta, Narayan, Jitendra, Slavov, Gancho, Romanov, Michael N, Borges, Rui, Machado, João Paulo, Khan, Imran, Springer, Mark S., Gatesy, John, Hoffmann, Federico G., Opazo, Juan C., Sawyer, Roger H., Kim, Heebal, Kim, Kyu-Won, Kim, Hyeon Jeong, Cho, Seoae, Li, Ning, Huang, Yinhua, Bruford, Michael W., Zhan, Xiangjiang, Dixon, Andrew, Bertelsen, Mads F., Derryberry, Elizabeth, Warren, Wesley, Wilson, Richard K, Li, Shengbin, Green, Richard E., Griffin, Darren, Johnson, Warren E., Haussler, David, Ryder, Oliver A., Willerslev, Eske, Graves, Gary R., Alström, Per, Fjeldså, Jon, Mindell, David P., Edwards, Scott V., Rahbek, Carsten, Burt, David W., Houde, Peter, Zhang, Yong, Yang, Huanming, Wang, Jian, Consortium, Avian Genome, Jarvis, Erich D., Gilbert, M. Thomas P., Wang, Jun

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A genomic timescale for placental mammal evolution von Foley, Nicole M, Mason, Victor C, Harris, Andrew J, Bredemeyer, Kevin R, Damas, Joana, Lewin, Harris A, Eizirik, Eduardo, Gatesy, John, Karlsson, Elinor K, Lindblad-Toh, Kerstin, Springer, Mark S, Murphy, William J

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Integrating gene annotation with orthology inference at scale von Kirilenko, Bogdan M, Munegowda, Chetan, Osipova, Ekaterina, Jebb, David, Sharma, Virag, Blumer, Moritz, Morales, Ariadna E, Ahmed, Alexis-Walid, Kontopoulos, Dimitrios-Georgios, Hilgers, Leon, Lindblad-Toh, Kerstin, Karlsson, Elinor K, Hiller, Michael

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The contribution of historical processes to contemporary extinction risk in placental mammals von Wilder, Aryn P, Supple, Megan A, Subramanian, Ayshwarya, Mudide, Anish, Swofford, Ross, Serres-Armero, Aitor, Steiner, Cynthia, Koepfli, Klaus-Peter, Genereux, Diane P, Karlsson, Elinor K, Lindblad-Toh, Kerstin, Marques-Bonet, Tomas, Munoz Fuentes, Violeta, Foley, Kathleen, Meyer, Wynn K, Ryder, Oliver A, Shapiro, Beth

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Mammalian evolution of human cis-regulatory elements and transcription factor binding sites von Andrews, Gregory, Fan, Kaili, Pratt, Henry E, Phalke, Nishigandha, Karlsson, Elinor K, Lindblad-Toh, Kerstin, Gazal, Steven, Moore, Jill E, Weng, Zhiping

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Relating enhancer genetic variation across mammals to complex phenotypes using machine learning von Kaplow, Irene M, Lawler, Alyssa J, Schäffer, Daniel E, Srinivasan, Chaitanya, Sestili, Heather H, Wirthlin, Morgan E, Phan, BaDoi N, Prasad, Kavya, Brown, Ashley R, Zhang, Xiaomeng, Foley, Kathleen, Genereux, Diane P, Karlsson, Elinor K, Lindblad-Toh, Kerstin, Meyer, Wynn K, Pfenning, Andreas R

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Insights into mammalian TE diversity through the curation of 248 genome assemblies von Osmanski, Austin B, Paulat, Nicole S, Korstian, Jenny, Grimshaw, Jenna R, Halsey, Michaela, Sullivan, Kevin A M, Moreno-Santillán, Diana D, Crookshanks, Claudia, Roberts, Jacquelyn, Garcia, Carlos, Johnson, Matthew G, Densmore, Llewellyn D, Stevens, Richard D, Rosen, Jeb, Storer, Jessica M, Hubley, Robert, Smit, Arian F A, Dávalos, Liliana M, Karlsson, Elinor K, Lindblad-Toh, Kerstin, Ray, David A

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