An Orally Bioavailable Antipoxvirus Compound (ST-246) Inhibits Extracellular Virus Formation and Protects Mice from Lethal Orthopoxvirus Challenge von GUANG YANG, PEVEAR, Daniel C, HUGGINS, John W, BAKER, Robert O, BULLER, R. L, TOUCHETTE, Erin, WALLER, Kem, SCHRIEWER, Jill, NEYTS, Johan, DECLERCQ, Erik, JONES, Kevin, HRUBY, Dennis, DAVIES, Marc H, JORDAN, Robert, COLLETT, Marc S, BAILEY, Tom, RIPPEN, Susan, BARONE, Linda, BURNS, Chris, RHODES, Gerry, TOHAN, Sanjeev

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structure of the RNA-dependent RNA polymerase from bovine viral diarrhea virus establishes the role of GTP in de novo initiation von Choi, K.H, Groarke, J.M, Young, D.C, Kuhn, R.J, Smith, J.L, Pevear, D.C, Rossmann, M.G

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Discovery of Taniborbactam (VNRX-5133): A Broad-Spectrum Serine- and Metallo-β-lactamase Inhibitor for Carbapenem-Resistant Bacterial Infections von Liu, Bin, Trout, Robert E. Lee, Chu, Guo-Hua, McGarry, Daniel, Jackson, Randy W, Hamrick, Jodie C, Daigle, Denis M, Cusick, Susan M, Pozzi, Cecilia, De Luca, Filomena, Benvenuti, Manuela, Mangani, Stefano, Docquier, Jean-Denis, Weiss, William J, Pevear, Daniel C, Xerri, Luigi, Burns, Christopher J

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VP1 Sequencing of All Human Rhinovirus Serotypes: Insights into Genus Phylogeny and Susceptibility to Antiviral Capsid-Binding Compounds von LEDFORD, Rebecca M, PATEL, Nitesh R, DEMENCZUK, Tina M, WATANYAR, Adiba, HERBERTZ, Torsten, COLLETT, Marc S, PEVEAR, Daniel C

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VNRX-5133 (Taniborbactam), a Broad-Spectrum Inhibitor of Serine- and Metallo-beta-Lactamases, Restores Activity of Cefepime in Enterobacterales and Pseudomonas aeruginosa von Hamrick, Jodie C., Docquier, Jean-Denis, Uehara, Tsuyoshi, Myers, Cullen L., Six, David A., Chatwin, Cassandra L., John, Kaitlyn J., Vernacchio, Salvador F., Cusick, Susan M., Trout, Robert E. L., Pozzi, Cecilia, De Luca, Filomena, Benvenuti, Manuela, Mangani, Stefano, Liu, Bin, Jackson, Randy W., Moeck, Greg, Xerri, Luigi, Burns, Christopher J., Pevear, Daniel C., Daigle, Denis M.

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Potent Antiviral Synergy between Monoclonal Antibody and Small-Molecule CCR5 Inhibitors of Human Immunodeficiency Virus Type 1 von MURGA, Jose D, FRANTI, Michael, PEVEAR, Daniel C, MADDON, Paul J, OLSON, William C

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Activity of Pleconaril against Enteroviruses von PEVEAR, D. C, TULL, T. M, SEIPEL, M. E, GROARKE, J. M

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Characterization of Poliovirus Variants Selected for Resistance to the Antiviral Compound V-073 von LIU, Hong-Mei, ROBERTS, Jason A, MOORE, Deborah, ANDERSON, Barbara, PALLANSCH, Mark A, PEVEAR, Daniel C, COLLETT, Marc S, OBERSTE, M. Steven

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In Vitro Antiviral Activity of V-073 against Polioviruses von OBERSTE, M. Steven, MOORE, Deborah, ANDERSON, Barbara, PALLANSCH, Mark A, PEVEAR, Daniel C, COLLETT, Marc S

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In Vitro Activity of Cefepime-Taniborbactam and Comparators against Clinical Isolates of Gram-Negative Bacilli from 2018 to 2020: Results from the Global Evaluation of Antimicrobia... von Karlowsky, James A, Hackel, Meredith A, Wise, Mark G, Six, David A, Uehara, Tsuyoshi, Daigle, Denis M, Cusick, Susan M, Pevear, Daniel C, Moeck, Greg, Sahm, Daniel F

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Relationship of Pleconaril Susceptibility and Clinical Outcomes in Treatment of Common Colds Caused by Rhinoviruses von PEVEAR, Daniel C, HAYDEN, Frederick G, DEMENCZUK, Tina M, BARONE, Linda R, MCKINLAY, Mark A, COLLETT, Marc S

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Ceftibuten-Ledaborbactam Activity against Multidrug-Resistant and Extended-Spectrum-β-Lactamase-Positive Clinical Isolates of Enterobacterales from a 2018-2020 Global Surveillance... von Karlowsky, James A, Wise, Mark G, Hackel, Meredith A, Pevear, Daniel C, Moeck, Greg, Sahm, Daniel F

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Discovery of VNRX-7145 (VNRX-5236 Etzadroxil): An Orally Bioavailable β‑Lactamase Inhibitor for Enterobacterales Expressing Ambler Class A, C, and D Enzymes von Trout, Robert E, Zulli, Allison, Mesaros, Eugen, Jackson, Randy W, Boyd, Steven, Liu, Bin, Hamrick, Jodie, Daigle, Denis, Chatwin, Cassandra L, John, Kaitlyn, McLaughlin, Lisa, Cusick, Susan M, Weiss, William J, Pulse, Mark E, Pevear, Daniel C, Moeck, Greg, Xerri, Luigi, Burns, Christopher J

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Microbiological Characterization of VNRX-5236, a Broad-Spectrum beta-Lactamase Inhibitor for Rescue of the Orally Bioavailable Cephalosporin Ceftibuten as a Carbapenem-Sparing Agen... von Chatwin, Cassandra L., Hamrick, Jodie C., Trout, Robert E. L., Myers, Cullen L., Cusick, Susan M., Weiss, William J., Pulse, Mark E., Xerri, Luigi, Burns, Christopher J., Moeck, Gregory, Daigle, Denis M., John, Kaitlyn, Uehara, Tsuyoshi, Pevear, Daniel C.

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Biographical Feature: Marc S. Collett (23 May 1951-11 June 2022): the Battle against Viral Disease Has Lost a Valiant Warrior, and the World Has Lost a Splendid Human Being von Glassman, Kimberly F, Brugge, Joan S, Purchio, Anthony F, Kakach, Laura T, Fuerst, Thomas R, Woods, Robert M, Stover, C Kendall, Chunduru, Srinivas K, Hincks, Jeffrey R, McKinlay, Mark A, Nash, Claude H, Pevear, Daniel C, Monath, Thomas P, Rice, Charles M, Peters, Pam

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Structural and Virological Studies of the Stages of Virus Replication That Are Affected by Antirhinovirus Compounds von YING ZHANG, SIMPSON, Alan A, LEDFORD, Rebecca M, BATOR, Carol M, CHAKRAVARTY, Sugoto, SKOCHKO, Gregory A, DEMENCZUK, Tina M, WATANYAR, Adiba, PEVEAR, Daniel C, ROSSMANN, Michael G

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Mechanism of Action of a Pestivirus Antiviral Compound von Baginski, Scott G., Pevear, Daniel C., Seipel, Marty, Siu Chi Chang Sun, Benetatos, Christopher A., Chunduru, Srinivas K., Rice, Charles M., Collett, Marc S.

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Attenuated Virulence of Pleconaril-Resistant Coxsackievirus B3 Variants von Groarke, James M., Pevear, Daniel C.

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Efficacy and Safety of Oral Pleconaril for Treatment of Colds Due to Picornaviruses in Adults: Results of 2 Double-Blind, Randomized, Placebo-Controlled Trials von Hayden, Frederick G., Herrington, Darrell T., Coats, Teresa L., Kim, Kenneth, Cooper, Ellen C., Villano, Stephen A., Liu, Siyu, Hudson, Spencer, Pevear, Daniel C., Collett, Marc, McKinlay, Mark

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The structure of coxsackievirus B3 at 3.5 å resolution von Muckelbauer, Jodi K, Kremer, Marcia, Minor, Iwona, Diana, Guy, Dutko, Frank J, Groarke, James, Pevear, Daniel C, Rossmann, Michael G

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