ISG15 conjugation to proteins on nascent DNA mitigates DNA replication stress von Wardlaw, Christopher P., Petrini, John H. J.

Volltext

Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway von Lovejoy, Courtney A, Li, Wendi, Reisenweber, Steven, Thongthip, Supawat, Bruno, Joanne, de Lange, Titia, De, Saurav, Petrini, John H J, Sung, Patricia A, Jasin, Maria, Rosenbluh, Joseph, Zwang, Yaara, Weir, Barbara A, Hatton, Charlie, Ivanova, Elena, Macconaill, Laura, Hanna, Megan, Hahn, William C, Lue, Neal F, Reddel, Roger R, Jiao, Yuchen, Kinzler, Kenneth, Vogelstein, Bert, Papadopoulos, Nickolas, Meeker, Alan K

Volltext

RTEL1 influences the abundance and localization of TERRA RNA von Ghisays, Fiorella, Garzia, Aitor, Wang, Hexiao, Canasto-Chibuque, Claudia, Hohl, Marcel, Savage, Sharon A., Tuschl, Thomas, Petrini, John H. J.

Volltext

The MRE11 complex: starting from the ends von Stracker, Travis H, Petrini, John H. J

Volltext

Modeling cancer genomic data in yeast reveals selection against ATM function during tumorigenesis von Hohl, Marcel, Mojumdar, Aditya, Hailemariam, Sarem, Kuryavyi, Vitaly, Ghisays, Fiorella, Sorenson, Kyle, Chang, Matthew, Taylor, Barry S., Patel, Dinshaw J., Burgers, Peter M., Cobb, Jennifer A., Petrini, John H. J.

Volltext

The telomeric protein TRF2 binds the ATM kinase and can inhibit the ATM-dependent DNA damage response von Karlseder, Jan, Hoke, Kristina, Mirzoeva, Olga K, Bakkenist, Christopher, Kastan, Michael B, Petrini, John H J, de Lange, Titia

Volltext

ZIP4H (TEX11) deficiency in the mouse impairs meiotic double strand break repair and the regulation of crossing over von Adelman, Carrie A, Petrini, John H J

Volltext

The carboxy terminus of NBS1 is required for induction of apoptosis by the MRE11 complex von Hussein, Hussein, Stracker, Travis H, Petrini, John H. J, Morales, Monica, Couto, Suzana S

Volltext

Cell cycle- and DNA repair pathway-specific effects of apoptosis on tumor suppression von Foster, Steven S, De, Saurav, Johnson, Linda K, Petrini, John H. J, Stracker, Travis H

Volltext

Chemical genetics reveals a specific requirement for Cdk2 activity in the DNA damage response and identifies Nbs1 as a Cdk2 substrate in human cells von Wohlbold, Lara, Merrick, Karl A, De, Saurav, Amat, Ramon, Kim, Jun Hyun, Larochelle, Stéphane, Allen, Jasmina J, Zhang, Chao, Shokat, Kevan M, Petrini, John H J, Fisher, Robert P

Volltext

Functions of the MRE11 complex in the development and maintenance of oocytes von Inagaki, Akiko, Roset, Ramon, Petrini, John H. J.

Volltext

The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair von Petrini, John H. J, Tainer, John A, Hopfner, Karl-Peter, Craig, Lisa, Moncalian, Gabriel, Zinkel, Robert A, Usui, Takehiko, Owen, Barbara A. L, Karcher, Annette, Henderson, Brendan, Bodmer, Jean-Luc, McMurray, Cynthia T, Carney, James P

Volltext

Aberrant topoisomerase-1 DNA lesions are pathogenic in neurodegenerative genome instability syndromes von Katyal, Sachin, Lee, Youngsoo, Nitiss, Karin C, Downing, Susanna M, Li, Yang, Shimada, Mikio, Zhao, Jingfeng, Russell, Helen R, Petrini, John H J, Nitiss, John L, McKinnon, Peter J

Volltext

The Mre11 Complex and the Response to Dysfunctional Telomeres von Attwooll, Claire L., Akpınar, Müge, Petrini, John H. J.

Volltext

The structure-selective endonucleases GEN1 and MUS81 mediate complementary functions in safeguarding the genome of proliferating B lymphocytes von Fernandez, Keith Conrad, Feeney, Laura, Smolkin, Ryan M, Yen, Wei-Feng, Matthews, Allysia J, Alread, William, Petrini, John H J, Chaudhuri, Jayanta

Volltext

Functional Interplay of the Mre11 Nuclease and Ku in the Response to Replication-Associated DNA Damage von Foster, Steven S., Balestrini, Alessia, Petrini, John H. J.

Volltext

In Situ Visualization of DNA Double-Strand Break Repair in Human Fibroblasts von Nelms, Benjamin E., Maser, Richard S., MacKay, James F., Lagally, Max G., John H. J. Petrini

Volltext

A recessive founder mutation in regulator of telomere elongation helicase 1, RTEL1, underlies severe immunodeficiency and features of Hoyeraal Hreidarsson syndrome von Ballew, Bari J, Joseph, Vijai, De, Saurav, Sarek, Grzegorz, Vannier, Jean-Baptiste, Stracker, Travis, Schrader, Kasmintan A, Small, Trudy N, O'Reilly, Richard, Manschreck, Chris, Harlan Fleischut, Megan M, Zhang, Liying, Sullivan, John, Stratton, Kelly, Yeager, Meredith, Jacobs, Kevin, Giri, Neelam, Alter, Blanche P, Boland, Joseph, Burdett, Laurie, Offit, Kenneth, Boulton, Simon J, Savage, Sharon A, Petrini, John H J

Volltext

Mouse DCUN1D1 (SCCRO) is required for spermatogenetic individualization von Huang, Guochang, Kaufman, Andrew J, Ryan, Russell J H, Romin, Yevgeniy, Huryn, Laryssa, Bains, Sarina, Manova-Todorova, Katia, Morris, Patricia L, Hunnicutt, Gary R, Adelman, Carrie A, Petrini, John H J, Ramanathan, Y, Singh, Bhuvanesh

Volltext

The Rad50 coiled-coil domain is indispensable for Mre11 complex functions von Petrini, John H J, Hohl, Marcel, Kwon, Youngho, Galván, Sandra Muñoz, Xue, Xiaoyu, Tous, Cristina, Aguilera, Andrés, Sung, Patrick

Volltext