Deubiquitinase Inhibition by Small-Molecule WP1130 Triggers Aggresome Formation and Tumor Cell Apoptosis von KAPURIA, Vaibhav, PETERSON, Luke F, DEXING FANG, BORNMANN, William G, TALPAZ, Moshe, DONATO, Nicholas J

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Usp9x regulates Ets-1 ubiquitination and stability to control NRAS expression and tumorigenicity in melanoma von Potu, Harish, Peterson, Luke F., Kandarpa, Malathi, Pal, Anupama, Sun, Hanshi, Durham, Alison, Harms, Paul W., Hollenhorst, Peter C., Eskiocak, Ugur, Talpaz, Moshe, Donato, Nicholas J.

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SETDB1 mediated histone H3 lysine 9 methylation suppresses MLL-fusion target expression and leukemic transformation von Ropa, James, Saha, Nirmalya, Hu, Hsiangyu, Peterson, Luke F, Talpaz, Moshe, Muntean, Andrew G

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Bcr-Abl ubiquitination and Usp9x inhibition block kinase signaling and promote CML cell apoptosis von Sun, Hanshi, Kapuria, Vaibhav, Peterson, Luke F., Fang, Dexing, Bornmann, William G., Bartholomeusz, Geoffrey, Talpaz, Moshe, Donato, Nicholas J.

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Recurrent Mutations in the MTOR Regulator RRAGC in Follicular Lymphoma von Ying, Zhang Xiao, Jin, Meiyan, Peterson, Luke F, Bernard, Denzil, Saiya-Cork, Kamlai, Yildiz, Mehmet, Wang, Shaomeng, Kaminski, Mark S, Chang, Alfred E, Klionsky, Daniel J, Malek, Sami N

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Usp5 links suppression of p53 and FAS levels in melanoma to the BRAF pathway von Potu, Harish, Peterson, Luke F, Pal, Anupama, Verhaegen, Monique, Cao, Juxiang, Talpaz, Moshe, Donato, Nicholas J

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Protein ISGylation modulates the JAK-STAT signaling pathway von Malakhova, Oxana A, Yan, Ming, Malakhov, Michael P, Yuan, Youzhong, Ritchie, Kenneth J, Kim, Keun Il, Peterson, Luke F, Shuai, Ke, Zhang, Dong-Er

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SETDB1 mediated histone H3 lysine 9 methylation suppresses MLL-fusion target expression and leukemic transformation von Ropa, James, Saha, Nirmalya, Hu, Hsiangyu, Peterson, Luke F, Talpaz, Moshe, Muntean, Andrew G

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Leukemia inhibitory factor functions in parallel with interleukin-6 to promote ovarian cancer growth von McLean, Karen, Tan, Lijun, Bolland, Danielle E., Coffman, Lan G., Peterson, Luke F., Talpaz, Moshe, Neamati, Nouri, Buckanovich, Ronald J.

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Selective inhibition of Ph-positive ALL cell growth through kinase-dependent and -independent effects by CDK6-specific PROTACs von De Dominici, Marco, Porazzi, Patrizia, Xiao, Youcai, Chao, Allen, Tang, Hsin-Yao, Kumar, Gaurav, Fortina, Paolo, Spinelli, Orietta, Rambaldi, Alessandro, Peterson, Luke F., Petruk, Svetlana, Barletta, Camilla, Mazo, Alexander, Cingolani, Gino, Salvino, Joseph M., Calabretta, Bruno

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AML1/RUNX1 Phosphorylation by Cyclin-Dependent Kinases Regulates the Degradation of AML1/RUNX1 by the Anaphase-Promoting Complex von Biggs, Joseph R., Peterson, Luke F., Zhang, Youhong, Kraft, Andrew S., Zhang, Dong-Er

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Targeting deubiquitinase activity with a novel small-molecule inhibitor as therapy for B-cell malignancies von Peterson, Luke F., Sun, Hanshi, Liu, Yihong, Potu, Harish, Kandarpa, Malathi, Ermann, Monika, Courtney, Stephen M., Young, Matthew, Showalter, Hollis D., Sun, Duxin, Jakubowiak, Andrzej, Malek, Sami N., Talpaz, Moshe, Donato, Nicholas J.

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Deletion of an AML1-ETO C-Terminal NcoR/SMRT-Interacting Region Strongly Induces Leukemia Development von Yan, Ming, Burel, Sebastien A., Peterson, Luke F., Kanbe, Eiki, Iwasaki, Hiromi, Boyapati, Anita, Hines, Robert, Akashi, Koichi, Zhang, Dong-Er, Vogt, Peter K.

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Downregulation of SOX2 by inhibition of Usp9X induces apoptosis in melanoma von Potu, Harish, Kandarpa, Malathi, Peterson, Luke F, Durham, Alison, Donato, Nicholas J, Talpaz, Moshe

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Tumor necrosis factor related apoptosis inducing ligand (TRAIL) regulates deubiquitinase USP5 in tumor cells von Potu, Harish, Kandarpa, Malathi, Peterson, Luke F., Donato, Nicholas J., Talpaz, Moshe

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Targeting STAT5 or STAT5-Regulated Pathways Suppresses Leukemogenesis of Ph+ Acute Lymphoblastic Leukemia von Minieri, Valentina, De Dominici, Marco, Porazzi, Patrizia, Mariani, Samanta A, Spinelli, Orietta, Rambaldi, Alessandro, Peterson, Luke F, Porcu, Pierluigi, Nevalainen, Marja T, Calabretta, Bruno

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The 8;21 translocation in leukemogenesis von Peterson, Luke F, Zhang, Dong-Er

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Follicular lymphoma-associated mutations in vacuolar ATPase ATP6V1B2 activate autophagic flux and mTOR von Wang, Fangyang, Gatica, Damián, Ying, Zhang Xiao, Peterson, Luke F, Kim, Peter, Bernard, Denzil, Saiya-Cork, Kamlai, Wang, Shaomeng, Kaminski, Mark S, Chang, Alfred E, Phillips, Tycel, Klionsky, Daniel J, Malek, Sami N

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Abstract 2881: Deubiquitinase Usp9x controls tumorigenicity through regulation of the Ets-1 transcription factor in melanoma von Potu, Harish, Peterson, Luke F. Peterson, Kandarpa, Malathi Kandarpa, Pal, Anupama Pal, Sun, Hanshi Sun, Harms, Paul W. Harms, Hollenhorst, Peter C. Hollenhorst, Eskiocak, Ugur Eskiocak, Talpaz, Moshe Talpaz, Donato, Nicholas J. Donato

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Targeting CDK6 and BCL2 Exploits the "MYB Addiction" of Ph + Acute Lymphoblastic Leukemia von De Dominici, Marco, Porazzi, Patrizia, Soliera, Angela Rachele, Mariani, Samanta A, Addya, Sankar, Fortina, Paolo, Peterson, Luke F, Spinelli, Orietta, Rambaldi, Alessandro, Martinelli, Giovanni, Ferrari, Anna, Iacobucci, Ilaria, Calabretta, Bruno

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