Label-free whole-cell assays: expanding the scope of GPCR screening von Scott, Clay W, Peters, Matthew F.

Volltext

Deconvoluting Kinase Inhibitor Induced Cardiotoxicity von Lamore, Sarah D, Ahlberg, Ernst, Boyer, Scott, Lamb, Michelle L, Hortigon-Vinagre, Maria P, Rodriguez, Victor, Smith, Godfrey L, Sagemark, Johanna, Carlsson, Lars, Bates, Stephanie M, Choy, Allison L, Stålring, Jonna, Scott, Clay W, Peters, Matthew F

Volltext

Cardiovascular Toxicity Induced by Kinase Inhibitors: Mechanisms and Preclinical Approaches von Lamore, Sarah D, Kohnken, Rebecca A, Peters, Matthew F, Kolaja, Kyle L

Volltext

Human induced pluripotent stem cells and their use in drug discovery for toxicity testing von Scott, Clay W, Peters, Matthew F., Dragan, Yvonne P.

Volltext

Developing in vitro assays to transform gastrointestinal safety assessment: potential for microphysiological systems von Peters, Matthew F., Choy, Allison L., Pin, Carmen, Leishman, Derek J., Moisan, Annie, Ewart, Lorna, Guzzie-Peck, Peggy J., Sura, Radhakrishna, Keller, Douglas A., Scott, Clay W., Kolaja, Kyle L.

Volltext

An impedance-based cellular assay using human iPSC-derived cardiomyocytes to quantify modulators of cardiac contractility von Scott, Clay W, Zhang, Xiaoyu, Abi-Gerges, Najah, Lamore, Sarah D, Abassi, Yama A, Peters, Matthew F

Volltext

Evaluation of Cellular Dielectric Spectroscopy, a Whole-Cell, Label-Free Technology for Drug Discovery on Gi-Coupled GPCRs von Peters, Matthew F., Knappenberger, Katharine S., Wilkins, Deidre, Sygowski, Linda A., Lazor, Lois Ann, Liu, Jianwei, Scott, Clay W.

Volltext

Human 3D Gastrointestinal Microtissue Barrier Function As a Predictor of Drug-Induced Diarrhea von Peters, Matthew F, Landry, Tim, Pin, Carmen, Maratea, Kim, Dick, Cortni, Wagoner, Matthew P, Choy, Allison L, Barthlow, Herb, Snow, Deb, Stevens, Zachary, Armento, Alex, Scott, Clay W, Ayehunie, Seyoum

Volltext

Human ileal organoid model recapitulates clinical incidence of diarrhea associated with small molecule drugs von Belair, David G., Visconti, Richard J., Hong, Miyoun, Marella, Mathieu, Peters, Matthew F., Scott, Clay W., Kolaja, Kyle L.

Volltext

Human Stem Cell-Derived Cardiomyocytes in Cellular Impedance Assays: Bringing Cardiotoxicity Screening to the Front Line von Peters, Matthew F., Lamore, Sarah D., Guo, Liang, Scott, Clay W, Kolaja, Kyle L.

Volltext

Evaluating Cellular Impedance Assays for Detection of GPCR Pleiotropic Signaling and Functional Selectivity von Peters, Matthew F., Scott, Clay W.

Volltext

Interference by Huntingtin and Atrophin-1 with CBP-Mediated Transcription Leading to Cellular Toxicity von Nucifora, Frederick C., Sasaki, Masayuki, Peters, Matthew F., Huang, Hui, Cooper, Jillian K., Yamada, Mitsunori, Takahashi, Hitoshi, Tsuji, Shoji, Troncoso, Juan, Dawson, Valina L., Dawson, Ted M., Ross, Christopher A.

Volltext

Cellular impedance assays for predictive preclinical drug screening of kinase inhibitor cardiovascular toxicity von Lamore, Sarah D, Kamendi, Harriet W, Scott, Clay W, Dragan, Yvonne P, Peters, Matthew F

Volltext

Evaluation of cellular impedance measures of cardiomyocyte cultures for drug screening applications von Peters, Matthew F, Scott, Clay W, Ochalski, Rafal, Dragan, Yvonne P

Volltext

Comparing label-free biosensors for pharmacological screening with cell-based functional assays von Peters, Matthew F, Vaillancourt, François, Heroux, Madeleine, Valiquette, Manon, Scott, Clay W

Volltext

Identification of short-acting κ-opioid receptor antagonists with anxiolytic-like activity von Peters, Matthew F., Zacco, Anna, Gordon, John, Maciag, Carla M., Litwin, Linda C., Thompson, Carolann, Schroeder, Patricia, Sygowski, Linda A., Piser, Timothy M., Brugel, Todd A.

Volltext

Interaction of Nitric Oxide Synthase with the Postsynaptic Density Protein PSD-95 and α1-Syntrophin Mediated by PDZ Domains von Brenman, Jay E, Chao, Daniel S, Gee, Stephen H, McGee, Aaron W, Craven, Sarah E, Santillano, Daniel R, Wu, Ziqiang, Huang, Fred, Xia, Houhui, Peters, Matthew F, Froehner, Stanley C, Bredt, David S

Volltext

Differential Association of Syntrophin Pairs with the Dystrophin Complex von Peters, Matthew F., Adams, Marvin E., Froehner, Stanley C.

Volltext

Preparation of human cDNAs encoding expanded polyglutamine repeats von PETERS, M. F, ROSS, C. A

Volltext

SAR development of a series of 8-azabicyclo[3.2.1]octan-3-yloxy-benzamides as kappa opioid receptor antagonists. Part 2 von Brugel, Todd A., Smith, Reed W., Balestra, Michael, Becker, Christopher, Daniels, Thalia, Koether, Gerard M., Throner, Scott R., Panko, Laura M., Brown, Dean G., Liu, Ruifeng, Gordon, John, Peters, Matthew F.

Volltext