Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation von Naumann, Marcel, Pal, Arun, Goswami, Anand, Lojewski, Xenia, Japtok, Julia, Vehlow, Anne, Naujock, Maximilian, Günther, René, Jin, Mengmeng, Stanslowsky, Nancy, Reinhardt, Peter, Sterneckert, Jared, Frickenhaus, Marie, Pan-Montojo, Francisco, Storkebaum, Erik, Poser, Ina, Freischmidt, Axel, Weishaupt, Jochen H., Holzmann, Karlheinz, Troost, Dirk, Ludolph, Albert C., Boeckers, Tobias M., Liebau, Stefan, Petri, Susanne, Cordes, Nils, Hyman, Anthony A., Wegner, Florian, Grill, Stephan W., Weis, Joachim, Storch, Alexander, Hermann, Andreas

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Modeling Parkinson’s disease in midbrain-like organoids von Smits, Lisa M., Reinhardt, Lydia, Reinhardt, Peter, Glatza, Michael, Monzel, Anna S., Stanslowsky, Nancy, Rosato-Siri, Marcelo D., Zanon, Alessandra, Antony, Paul M., Bellmann, Jessica, Nicklas, Sarah M., Hemmer, Kathrin, Qing, Xiaobing, Berger, Emanuel, Kalmbach, Norman, Ehrlich, Marc, Bolognin, Silvia, Hicks, Andrew A., Wegner, Florian, Sterneckert, Jared L., Schwamborn, Jens C.

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Genetic Correction of a LRRK2 Mutation in Human iPSCs Links Parkinsonian Neurodegeneration to ERK-Dependent Changes in Gene Expression von Reinhardt, Peter, Schmid, Benjamin, Burbulla, Lena F., Schöndorf, David C., Wagner, Lydia, Glatza, Michael, Höing, Susanne, Hargus, Gunnar, Heck, Susanna A., Dhingra, Ashutosh, Wu, Guangming, Müller, Stephan, Brockmann, Kathrin, Kluba, Torsten, Maisel, Martina, Krüger, Rejko, Berg, Daniela, Tsytsyura, Yaroslav, Thiel, Cora S., Psathaki, Olympia-Ekaterini, Klingauf, Jürgen, Kuhlmann, Tanja, Klewin, Marlene, Müller, Heiko, Gasser, Thomas, Schöler, Hans R., Sterneckert, Jared

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Mass independent isotopic fractionation: A key to plasma chemistry von Robert, François, Reinhardt, Peter

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Derivation and expansion using only small molecules of human neural progenitors for neurodegenerative disease modeling von Reinhardt, Peter, Glatza, Michael, Hemmer, Kathrin, Tsytsyura, Yaroslav, Thiel, Cora S, Höing, Susanne, Moritz, Sören, Parga, Juan A, Wagner, Lydia, Bruder, Jan M, Wu, Guangming, Schmid, Benjamin, Röpke, Albrecht, Klingauf, Jürgen, Schwamborn, Jens C, Gasser, Thomas, Schöler, Hans R, Sterneckert, Jared

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Dual truncation of tau by caspase-2 accelerates its CHIP-mediated degradation von Reinhardt, Lydia, Musacchio, Fabrizio, Bichmann, Maria, Behrendt, Annika, Ercan-Herbst, Ebru, Stein, Juliane, Becher, Isabelle, Haberkant, Per, Mader, Julia, Schöndorf, David C., Schmitt, Melanie, Korffmann, Jürgen, Reinhardt, Peter, Pohl, Christian, Savitski, Mikhail, Klein, Corinna, Gasparini, Laura, Fuhrmann, Martin, Ehrnhoefer, Dagmar E.

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Alzheimer's disease‐associated R47H TREM2 increases, but wild‐type TREM2 decreases, microglial phagocytosis of synaptosomes and neuronal loss von Popescu, Alma S., Butler, Claire A., Allendorf, David H., Piers, Thomas M., Mallach, Anna, Roewe, Julian, Reinhardt, Peter, Cinti, Alessandro, Redaelli, Loredana, Boudesco, Christophe, Pradier, Laurent, Pocock, Jennifer M., Thornton, Peter, Brown, Guy C.

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Isogenic FUS-eGFP iPSC Reporter Lines Enable Quantification of FUS Stress Granule Pathology that Is Rescued by Drugs Inducing Autophagy von Marrone, Lara, Poser, Ina, Casci, Ian, Japtok, Julia, Reinhardt, Peter, Janosch, Antje, Andree, Cordula, Lee, Hyun O., Moebius, Claudia, Koerner, Ellen, Reinhardt, Lydia, Cicardi, Maria Elena, Hackmann, Karl, Klink, Barbara, Poletti, Angelo, Alberti, Simon, Bickle, Marc, Hermann, Andreas, Pandey, Udai Bhan, Hyman, Anthony A., Sterneckert, Jared L.

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Author Correction: Fully co-factor-free ClearTau platform produces seeding-competent Tau fibrils for reconstructing pathological Tau aggregates von Limorenko, Galina, Tatli, Meltem, Kolla, Rajasekhar, Nazarov, Sergey, Weil, Marie-Theres, Schöndorf, David C., Geist, Daniela, Reinhardt, Peter, Ehrnhoefer, Dagmar E., Stahlberg, Henning, Gasparini, Laura, Lashuel, Hilal A.

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Leucine-Rich Repeat Kinase 2 Influences Fate Decision of Human Monocytes Differentiated from Induced Pluripotent Stem Cells von Speidel, Anna, Felk, Sandra, Reinhardt, Peter, Sterneckert, Jared, Gillardon, Frank

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4‐Aminopyridine Induced Activity Rescues Hypoexcitable Motor Neurons from Amyotrophic Lateral Sclerosis Patient‐Derived Induced Pluripotent Stem Cells von Naujock, Maximilian, Stanslowsky, Nancy, Bufler, Sebastian, Naumann, Marcel, Reinhardt, Peter, Sterneckert, Jared, Kefalakes, Ekaterini, Kassebaum, Carola, Bursch, Franziska, Lojewski, Xenia, Storch, Alexander, Frickenhaus, Marie, Boeckers, Tobias M., Putz, Stefan, Demestre, Maria, Liebau, Stefan, Klingenstein, Moritz, Ludolph, Albert C., Dengler, Reinhard, Kim, Kwang‐Soo, Hermann, Andreas, Wegner, Florian, Petri, Susanne

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Reproducibility of Molecular Phenotypes after Long-Term Differentiation to Human iPSC-Derived Neurons: A Multi-Site Omics Study von Volpato, Viola, Smith, James, Sandor, Cynthia, Ried, Janina S., Baud, Anna, Handel, Adam, Newey, Sarah E., Wessely, Frank, Attar, Moustafa, Whiteley, Emma, Chintawar, Satyan, Verheyen, An, Barta, Thomas, Lako, Majlinda, Armstrong, Lyle, Muschet, Caroline, Artati, Anna, Cusulin, Carlo, Christensen, Klaus, Patsch, Christoph, Sharma, Eshita, Nicod, Jerome, Brownjohn, Philip, Stubbs, Victoria, Heywood, Wendy E., Gissen, Paul, De Filippis, Roberta, Janssen, Katharina, Reinhardt, Peter, Adamski, Jerzy, Royaux, Ines, Peeters, Pieter J., Terstappen, Georg C., Graf, Martin, Livesey, Frederick J., Akerman, Colin J., Mills, Kevin, Bowden, Rory, Nicholson, George, Webber, Caleb, Cader, M. Zameel, Lakics, Viktor

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Fully co-factor-free ClearTau platform produces seeding-competent Tau fibrils for reconstructing pathological Tau aggregates von Limorenko, Galina, Tatli, Meltem, Kolla, Rajasekhar, Nazarov, Sergey, Weil, Marie-Theres, Schöndorf, David C., Geist, Daniela, Reinhardt, Peter, Ehrnhoefer, Dagmar E., Stahlberg, Henning, Gasparini, Laura, Lashuel, Hilal A.

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Generation of iPSCs carrying a common LRRK2 risk allele for in vitro modeling of idiopathic Parkinson's disease von Marrone, Lara, Bus, Christine, Schöndorf, David, Fitzgerald, Julia Catherine, Kübler, Manuela, Schmid, Benjamin, Reinhardt, Peter, Reinhardt, Lydia, Deleidi, Michela, Levin, Tanya, Meixner, Andrea, Klink, Barbara, Glatza, Michael, Gloeckner, Christian Johannes, Gasser, Thomas, Sterneckert, Jared

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Phorbol-12-myristate-13-acetate is a potent enhancer of B cells with a granzyme B+ regulatory phenotype von Veh, Johanna, Mangold, Charlotte, Felsen, Anja, Ludwig, Carolin, Gerstner, Lisa, Reinhardt, Peter, Schrezenmeier, Hubert, Fabricius, Dorit, Jahrsdörfer, Bernd

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Dual Inhibition of GSK3β and CDK5 Protects the Cytoskeleton of Neurons from Neuroinflammatory-Mediated Degeneration In Vitro and In Vivo von Reinhardt, Lydia, Kordes, Susanne, Reinhardt, Peter, Glatza, Michael, Baumann, Matthias, Drexler, Hannes C.A., Menninger, Sascha, Zischinsky, Gunther, Eickhoff, Jan, Fröb, Claudia, Bhattarai, Prabesh, Arulmozhivarman, Guruchandar, Marrone, Lara, Janosch, Antje, Adachi, Kenjiro, Stehling, Martin, Anderson, Eric N., Abo-Rady, Masin, Bickle, Marc, Pandey, Udai Bhan, Reimer, Michell M., Kizil, Caghan, Schöler, Hans R., Nussbaumer, Peter, Klebl, Bert, Sterneckert, Jared L.

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Combined Dendritic and Axonal Deterioration Are Responsible for Motoneuronopathy in Patient-Derived Neuronal Cell Models of Chorea-Acanthocytosis von Glaß, Hannes, Neumann, Patrick, Pal, Arun, Reinhardt, Peter, Storch, Alexander, Sterneckert, Jared, Hermann, Andreas

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Human iPSC models of neuronal ceroid lipofuscinosis capture distinct effects of TPP1 and CLN3 mutations on the endocytic pathway von Lojewski, Xenia, Staropoli, John F, Biswas-Legrand, Sunita, Simas, Alexandra M, Haliw, Larissa, Selig, Martin K, Coppel, Scott H, Goss, Kendrick A, Petcherski, Anton, Chandrachud, Uma, Sheridan, Steven D, Lucente, Diane, Sims, Katherine B, Gusella, James F, Sondhi, Dolan, Crystal, Ronald G, Reinhardt, Peter, Sterneckert, Jared, Schöler, Hans, Haggarty, Stephen J, Storch, Alexander, Hermann, Andreas, Cotman, Susan L

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A validated antibody panel for the characterization of tau post-translational modifications von Ercan, Ebru, Eid, Sameh, Weber, Christian, Kowalski, Alexandra, Bichmann, Maria, Behrendt, Annika, Matthes, Frank, Krauss, Sybille, Reinhardt, Peter, Fulle, Simone, Ehrnhoefer, Dagmar E

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Stepwise acquirement of hallmark neuropathology in FUS-ALS iPSC models depends on mutation type and neuronal aging von Japtok, Julia, Lojewski, Xenia, Naumann, Marcel, Klingenstein, Moritz, Reinhardt, Peter, Sterneckert, Jared, Putz, Stefan, Demestre, Maria, Boeckers, Tobias M, Ludolph, Albert C, Liebau, Stefan, Storch, Alexander, Hermann, Andreas

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