Galectin 3 as a guardian of the tumor microenvironment von Ruvolo, Peter P.

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Role of protein phosphatases in the cancer microenvironment von Ruvolo, Peter P.

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The broken “Off” switch in cancer signaling: PP2A as a regulator of tumorigenesis, drug resistance, and immune surveillance von Ruvolo, Peter P.

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Selective BCL-2 inhibition by ABT-199 causes on-target cell death in acute myeloid leukemia von Pan, Rongqing, Hogdal, Leah J, Benito, Juliana M, Bucci, Donna, Han, Lina, Borthakur, Gautam, Cortes, Jorge, DeAngelo, Daniel J, Debose, Lakeisha, Mu, Hong, Döhner, Hartmut, Gaidzik, Verena I, Galinsky, Ilene, Golfman, Leonard S, Haferlach, Torsten, Harutyunyan, Karine G, Hu, Jianhua, Leverson, Joel D, Marcucci, Guido, Müschen, Markus, Newman, Rachel, Park, Eugene, Ruvolo, Peter P, Ruvolo, Vivian, Ryan, Jeremy, Schindela, Sonja, Zweidler-McKay, Patrick, Stone, Richard M, Kantarjian, Hagop, Andreeff, Michael, Konopleva, Marina, Letai, Anthony G

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LGALS1 acts as a pro-survival molecule in AML von Ruvolo, Peter P., Ma, Huaxian, Ruvolo, Vivian R., Zhang, Xiaorui, Post, Sean M., Andreeff, Michael

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Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia von Konopleva, Marina, Contractor, Rooha, Tsao, Twee, Samudio, Ismael, Ruvolo, Peter P., Kitada, Shinichi, Deng, Xingming, Zhai, Dayong, Shi, Yue-Xi, Sneed, Thomas, Verhaegen, Monique, Soengas, Maria, Ruvolo, Vivian R., McQueen, Teresa, Schober, Wendy D., Watt, Julie C., Jiffar, Tilahun, Ling, Xiaoyang, Marini, Frank C., Harris, David, Dietrich, Martin, Estrov, Zeev, McCubrey, James, May, W. Stratford, Reed, John C., Andreeff, Michael

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AXL/MERTK inhibitor ONO-7475 potently synergizes with venetoclax and overcomes venetoclax resistance to kill FLT3 -ITD acute myeloid leukemia von Post, Sean M, Ma, Huaxian, Malaney, Prerna, Zhang, Xiaorui, Aitken, Marisa J L, Mak, Po Yee, Ruvolo, Vivian R, Yasuhiro, Tomoko, Kozaki, Ryohei, Chan, Lauren E, Ostermann, Lauren B, Konopleva, Marina, Carter, Bing Z, DiNardo, Courtney, Andreeff, Michael D, Khoury, Joseph D, Ruvolo, Peter P

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TP53/miR-34a-associated signaling targets SERPINE1 expression in human pancreatic cancer von Akula, Shaw M., Ruvolo, Peter P., McCubrey, James A.

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Distinct protein signatures of acute myeloid leukemia bone marrow-derived stromal cells are prognostic for patient survival von Kornblau, Steven M, Ruvolo, Peter P, Wang, Rui-Yu, Battula, V Lokesh, Shpall, Elizabeth J, Ruvolo, Vivian R, McQueen, Teresa, Qui, YiHua, Zeng, Zhihong, Pierce, Sherry, Jacamo, Rodrigo, Yoo, Suk-Young, Le, Phuong M, Sun, Jeffrey, Hail, Jr, Numsen, Konopleva, Marina, Andreeff, Michael

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Combination of galectin inhibitor GCS-100 and BH3 mimetics eliminates both p53 wild type and p53 null AML cells von Ruvolo, Peter P., Ruvolo, Vivian R., Benton, Christopher B., AlRawi, Ahmed, Burks, Jared K., Schober, Wendy, Rolke, James, Tidmarsh, George, Hail, Numsen, Eric Davis, R., Andreeff, Michael

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Preclinical and Early Clinical Evaluation of the Oral AKT Inhibitor, MK-2206, for the Treatment of Acute Myelogenous Leukemia von KONOPLEVA, Marina Y, WALTER, Roland B, HONGBO LU, DEBOSE, Lakiesha, BURGER, Jan A, ANDREEFF, Michael, WENBIN LIU, BAGGERLY, Keith A, KORNBLAU, Steven M, DOYLE, L. Austin, ESTEY, Elihu H, KANTARJIAN, Hagop M, FADERL, Stefan H, JABBOUR, Elias J, ZHIHONG ZENG, BORTHAKUR, Gautam, XUELIN HUANG, KADIA, Tapan M, RUVOLO, Peter P, FELIU, Jennie B

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Inhibition of Mcl-1 with the pan–Bcl-2 family inhibitor (–)BI97D6 overcomes ABT-737 resistance in acute myeloid leukemia von Pan, Rongqing, Ruvolo, Vivian R., Wei, Jun, Konopleva, Marina, Reed, John C., Pellecchia, Maurizio, Andreeff, Michael, Ruvolo, Peter P.

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The Herculean task of killing cancer cells: Suppression of FOXO3A in acute leukemia involves a hydra of multiple survival kinases von Ruvolo, Peter P.

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Galectins as regulators of cell survival in the leukemia niche von Ruvolo, Peter P.

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Targeting PKC-mediated signal transduction pathways using enzastaurin to promote apoptosis in acute myeloid leukemia-derived cell lines and blast cells von Ruvolo, Peter P., Zhou, Liran, Watt, Julie C., Ruvolo, Vivian R., Burks, Jared K., Jiffar, Tilahun, Kornblau, Steven, Konopleva, Marina, Andreeff, Michael

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Atg7 suppression enhances chemotherapeutic agent sensitivity and overcomes stroma-mediated chemoresistance in acute myeloid leukemia von Piya, Sujan, Kornblau, Steven M., Ruvolo, Vivian R., Mu, Hong, Ruvolo, Peter P., McQueen, Teresa, Davis, R.Eric, Hail, Numsen, Kantarjian, Hagop, Andreeff, Michael, Borthakur, Gautam

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GSK-3 as a novel prognostic indicator in leukemia von Ruvolo, Peter P.

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Intracellular signal transduction pathways activated by ceramide and its metabolites von Ruvolo, Peter P.

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Combining Anti-Mir-155 with Chemotherapy for the Treatment of Lung Cancers von Van Roosbroeck, Katrien, Fanini, Francesca, Setoyama, Tetsuro, Ivan, Cristina, Rodriguez-Aguayo, Cristian, Fuentes-Mattei, Enrique, Xiao, Lianchun, Vannini, Ivan, Redis, Roxana S, D'Abundo, Lucilla, Zhang, Xinna, Nicoloso, Milena S, Rossi, Simona, Gonzalez-Villasana, Vianey, Rupaimoole, Rajesha, Ferracin, Manuela, Morabito, Fortunato, Neri, Antonino, Ruvolo, Peter P, Ruvolo, Vivian R, Pecot, Chad V, Amadori, Dino, Abruzzo, Lynne, Calin, Steliana, Wang, Xuemei, You, M James, Ferrajoli, Alessandra, Orlowski, Robert, Plunkett, William, Lichtenberg, Tara M, Davuluri, Ramana V, Berindan-Neagoe, Ioana, Negrini, Massimo, Wistuba, Ignacio I, Kantarjian, Hagop M, Sood, Anil K, Lopez-Berestein, Gabriel, Keating, Michael J, Fabbri, Muller, Calin, George A

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Anexelekto/MER tyrosine kinase inhibitor ONO-7475 arrests growth and kills FMS-like tyrosine kinase 3-internal tandem duplication mutant acute myeloid leukemia cells by diverse mec... von Ruvolo, Peter P, Ma, Huaxian, Ruvolo, Vivian R, Zhang, Xiaorui, Mu, Hong, Schober, Wendy, Hernandez, Ivonne, Gallardo, Miguel, Khoury, Joseph D, Cortes, Jorge, Andreeff, Michael, Post, Sean M

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