THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Catalytic receptors von Alexander, Stephen PH, Fabbro, Doriano, Kelly, Eamonn, Mathie, Alistair, Peters, John A, Veale, Emma L, Armstrong, Jane F, Faccenda, Elena, Harding, Simon D, Pawson, Adam J, Southan, Christopher, Davies, Jamie A, Beuve, Annie, Brouckaert, Peter, Bryant, Clare, Burnett, John C., Farndale, Richard W., Friebe, Andreas, Garthwaite, John, Hobbs, Adrian J., Jarvis, Gavin E., Kuhn, Michaela, MacEwan, David, Monie, Tom P., Papapetropoulos, Andreas, Potter, Lincoln R., Schmidt, Harald H.H.W., Szabo, Csaba, Waldman, Scott A.

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Cardioprotection by H2S engages a cGMP-dependent protein kinase G/phospholamban pathway von Bibli, Sofia-Iris, Andreadou, Ioanna, Chatzianastasiou, Athanasia, Tzimas, Christos, Sanoudou, Despina, Kranias, Evangelia, Brouckaert, Peter, Coletta, Ciro, Szabo, Csaba, Kremastinos, Dimitrios Th, Iliodromitis, Efstathios K, Papapetropoulos, Andreas

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Of mice, men, and inflammation von Cauwels, Anje, Vandendriessche, Benjamin, Brouckaert, Peter

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Loss of α1β1 Soluble Guanylate Cyclase, the Major Nitric Oxide Receptor, Leads to Moyamoya and Achalasia von Hervé, Dominique, Philippi, Anne, Belbouab, Reda, Zerah, Michel, Chabrier, Stéphane, Collardeau-Frachon, Sophie, Bergametti, Francoise, Essongue, Aurore, Berrou, Eliane, Krivosic, Valérie, Sainte-Rose, Christian, Houdart, Emmanuel, Adam, Frédéric, Billiemaz, Kareen, Lebret, Marilyne, Roman, Sabine, Passemard, Sandrine, Boulday, Gwenola, Delaforge, Audrey, Guey, Stéphanie, Dray, Xavier, Chabriat, Hugues, Brouckaert, Peter, Bryckaert, Maryjke, Tournier-Lasserve, Elisabeth

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Ferulic acid-4-O-sulfate rather than ferulic acid relaxes arteries and lowers blood pressure in mice von Van Rymenant, Evelien, Van Camp, John, Pauwels, Bart, Boydens, Charlotte, Vanden Daele, Laura, Beerens, Katrijn, Brouckaert, Peter, Smagghe, Guy, Kerimi, Asimina, Williamson, Gary, Grootaert, Charlotte, Van de Voorde, Johan

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Safe eradication of large established tumors using neovasculature‐targeted tumor necrosis factor‐based therapies von Huyghe, Leander, Van Parys, Alexander, Cauwels, Anje, Van Lint, Sandra, De Munter, Stijn, Bultinck, Jennyfer, Zabeau, Lennart, Hostens, Jeroen, Goethals, An, Vanderroost, Nele, Verhee, Annick, Uzé, Gilles, Kley, Niko, Peelman, Frank, Vandekerckhove, Bart, Brouckaert, Peter, Tavernier, Jan

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Inhaled Nitric Oxide Improves Outcomes After Successful Cardiopulmonary Resuscitation in Mice von MINAMISHIMA, Shizuka, KIDA, Kotaro, LIU, Christina H, BLOCH, Kenneth D, ICHINOSE, Fumito, TOKUDA, Kentaro, HUIFANG WANG, SIPS, Patrick Y, KOSUGI, Shizuko, MANDEVILLE, Joseph B, BUYS, Emmanuel S, BROUCKAERT, Peter, LIU, Philip K

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Microcirculatory Function during Endotoxemia-A Functional Citrulline-Arginine-NO Pathway and NOS3 Complex Is Essential to Maintain the Microcirculation von Wijnands, Karolina A. P., Meesters, Dennis M., Vandendriessche, Benjamin, Briede, Jacob J., van Eijk, Hans M. H., Brouckaert, Peter, Cauwels, Anje, Lamers, Wouter H., Poeze, Martijn

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ARGX-110, a highly potent antibody targeting CD70, eliminates tumors via both enhanced ADCC and immune checkpoint blockade von Silence, Karen, Dreier, Torsten, Moshir, Mahan, Ulrichts, Peter, Gabriels, Sofie ME, Saunders, Michael, Wajant, Harald, Brouckaert, Peter, Huyghe, Leander, Van Hauwermeiren, Tim, Thibault, Alain, De Haard, Hans J

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Brown Adipose Tissue Blood Flow and Mass in Obesity: A Contrast Ultrasound Study in Mice von Clerte, Maëva, MD, Baron, David M., MD, Brouckaert, Peter, MD, PhD, Ernande, Laura, MD, PhD, Raher, Michael J., BS, Flynn, Aidan W., MD, PhD, Picard, Michael H., MD, Bloch, Kenneth D., MD, Buys, Emmanuel S., PhD, Scherrer-Crosbie, Marielle, MD, PhD

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Caspase inhibition causes hyperacute tumor necrosis factor-induced shock via oxidative stress and phospholipase A2 von Cauwels, Anje, Janssen, Ben, Waeytens, Anouk, Cuvelier, Claude, Brouckaert, Peter

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The Role of Soluble Guanylyl Cyclase in Chronic Obstructive Pulmonary Disease von GLYNOS, Constantinos, DUPONT, Lisa L, VASSILAKOPOULOS, Theodoros, PAPAPETROPOULOS, Andreas, BROUCKAERT, Peter, GIANNIS, Athanassios, JOOS, Guy F, BRACKE, Ken R, BRUSSELLE, Guy G

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Distinct Myocardial Mechanisms Underlie Cardiac Dysfunction in Endotoxemic Male and Female Mice von Hobai, Ion A, Aziz, Kanwal, Buys, Emmanuel S, Brouckaert, Peter, Siwik, Deborah A, Colucci, Wilson S

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Gender-specific hypertension and responsiveness to nitric oxide in sGCα1 knockout mice von Buys, Emmanuel S., Sips, Patrick, Vermeersch, Pieter, Raher, Michael J., Rogge, Elke, Ichinose, Fumito, Dewerchin, Mieke, Bloch, Kenneth D., Janssens, Stefan, Brouckaert, Peter

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The soluble guanylate cyclase activator BAY 58-2667 protects against morbidity and mortality in endotoxic shock by recoupling organ systems von Vandendriessche, Benjamin, Rogge, Elke, Goossens, Vera, Vandenabeele, Peter, Stasch, Johannes-Peter, Brouckaert, Peter, Cauwels, Anje

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Transcriptome analysis in patients with chronic kidney disease on hemodialysis disclosing a key role for CD16+CX3CR1+ monocytes von Schepers, Eva, Houthuys, Erica, Dhondt, Annemieke, De Meyer, Grim, Neirynck, Nathalie, Bernaert, Pascale, Van den Bergh, Rafael, Brouckaert, Peter, Vanholder, Raymond, Glorieux, Griet

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Newly Identified NO‐Sensor Guanylyl Cyclase/Connexin 43 Association Is Involved in Cardiac Electrical Function von Crassous, Pierre‐Antoine, Shu, Ping, Huang, Can, Gordan, Richard, Brouckaert, Peter, Lampe, Paul D., Xie, Lai‐Hua, Beuve, Annie

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Soluble guanylate cyclase α1-deficient mice: a novel murine model for primary open angle glaucoma von Buys, Emmanuel S, Ko, Yu-Chieh, Alt, Clemens, Hayton, Sarah R, Jones, Alexander, Tainsh, Laurel T, Ren, Ruiyi, Giani, Andrea, Clerté, Maeva, Abernathy, Emma, Tainsh, Robert E T, Oh, Dong-Jin, Malhotra, Rajeev, Arora, Pankaj, de Waard, Nadine, Yu, Binglan, Turcotte, Raphael, Nathan, Daniel, Scherrer-Crosbie, Marielle, Loomis, Stephanie J, Kang, Jae H, Lin, Charles P, Gong, Haiyan, Rhee, Douglas J, Brouckaert, Peter, Wiggs, Janey L, Gregory, Meredith S, Pasquale, Louis R, Bloch, Kenneth D, Ksander, Bruce R

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Critical role for small and large conductance calcium-dependent potassium channels in endotoxemia and TNF toxicity von Cauwels, Anje, Brouckaert, Peter

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Toll-like Receptor 4 Signaling Confers Cardiac Protection against Ischemic Injury via Inducible Nitric Oxide Synthase- and Soluble Guanylate Cyclase-dependent Mechanisms von WANG, E, YAN FENG, MING ZHANG, LIN ZOU, YAN LI, BUYS, Emmanuel S, PEIGEN HUANG, BROUCKAERT, Peter, WEI CHAO

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