N-acetylaspartate catabolism determines cytosolic acetyl-CoA levels and histone acetylation in brown adipocytes von Prokesch, A., Pelzmann, H. J., Pessentheiner, A. R., Huber, K., Madreiter-Sokolowski, C. T., Drougard, A., Schittmayer, M., Kolb, D., Magnes, C., Trausinger, G., Graier, W. F., Birner-Gruenberger, R., Pospisilik, J. A., Bogner-Strauss, J. G.

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Interventional hepatic ApoC-III knockdown improves atherosclerotic plaque stability and remodeling via lowering remnant lipoproteins von Gordts, P., Ramms, B., Pessentheiner, A., Sun, X., Ducasa, G.M., Tsimikas, S., Witztum, J.L.

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The human milk oligosaccharide 3’sialyllactose promotes inflammation resolution and reduces atherosclerosis development von Pessentheiner, A., Spann, N., Collins, C., Ramms, B., Chiang, A., Wang, Y., Quach, A., Booshehri, L., Hammond, A., Tognaccini, C., Latasiewicz, J., Witztum, J.L., Hoffman, H., Lewis, N., Glass, C., Bode, L., Gordts, P.

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Proteoglycans in Obesity-Associated Metabolic Dysfunction and Meta-Inflammation von Pessentheiner, Ariane R, Ducasa, G Michelle, Gordts, Philip L S M

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Characterization of distinct subpopulations of hepatic macrophages in HFD/obese mice von Morinaga, Hidetaka, Mayoral, Rafael, Heinrichsdorff, Jan, Osborn, Olivia, Franck, Niclas, Hah, Nasun, Walenta, Evelyn, Bandyopadhyay, Gautam, Pessentheiner, Ariane R, Chi, Tyler J, Chung, Heekyung, Bogner-Strauss, Juliane G, Evans, Ronald M, Olefsky, Jerrold M, Oh, Da Young

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Metabolite and transcriptome analysis during fasting suggest a role for the p53-Ddit4 axis in major metabolic tissues von Schupp, Michael, Chen, Fang, Briggs, Erika R, Rao, Shilpa, Pelzmann, Helmut J, Pessentheiner, Ariane R, Bogner-Strauss, Juliane G, Lazar, Mitchell A, Baldwin, Don, Prokesch, Andreas

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ApoC-III ASO promotes tissue LPL activity in the absence of apoE-mediated TRL clearance von Ramms, Bastian, Patel, Sohan, Nora, Chelsea, Pessentheiner, Ariane R., Chang, Max W., Green, Courtney R., Golden, Gregory J., Secrest, Patrick, Krauss, Ronald M., Metallo, Christian M., Benner, Christopher, Alexander, Veronica J., Witztum, Joseph L., Tsimikas, Sotirios, Esko, Jeffrey D., Gordts, Philip L.S.M.

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A Gpr120-selective agonist improves insulin resistance and chronic inflammation in obese mice von Oh, Da Young, Walenta, Evelyn, Akiyama, Taro E, Lagakos, William S, Lackey, Denise, Pessentheiner, Ariane R, Sasik, Roman, Hah, Nasun, Chi, Tyler J, Cox, Jason M, Powels, Mary Ann, Di Salvo, Jerry, Sinz, Christopher, Watkins, Steven M, Armando, Aaron M, Chung, Heekyung, Evans, Ronald M, Quehenberger, Oswald, McNelis, Joanne, Bogner-Strauss, Juliane G, Olefsky, Jerrold M

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Positive Reinforcing Mechanisms between GPR120 and PPARγ Modulate Insulin Sensitivity von Paschoal, Vivian A., Walenta, Evelyn, Talukdar, Saswata, Pessentheiner, Ariane R., Osborn, Olivia, Hah, Nasun, Chi, Tyler J., Tye, George L., Armando, Aaron M., Evans, Ronald M., Chi, Nai-Wen, Quehenberger, Oswald, Olefsky, Jerrold M., Oh, Da Young

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Adipocyte SIRT1 knockout promotes PPAR γ activity, adipogenesis and insulin sensitivity in chronic-HFD and obesity von Mayoral, Rafael, Osborn, Olivia, McNelis, Joanne, Johnson, Andrew M, Oh, Da Young, Izquierdo, Cristina Llorente, Chung, Heekyung, Li, Pingping, Traves, Paqui G, Bandyopadhyay, Gautam, Pessentheiner, Ariane R, Ofrecio, Jachelle M, Cook, Joshua R, Qiang, Li, Accili, Domenico, Olefsky, Jerrold M

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Reduction of Liver Heparan Sulfate Proteoglycans Promotes Endocrine Benefits of Therapeutic FGF1 von Vi Quach, Anthony, Pessentheiner, Ariane, Gordts, Philip

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Loss of ABHD15 Impairs the Anti-lipolytic Action of Insulin by Altering PDE3B Stability and Contributes to Insulin Resistance von Xia, Wenmin, Pessentheiner, Ariane R., Hofer, Dina C., Amor, Melina, Schreiber, Renate, Schoiswohl, Gabriele, Eichmann, Thomas O., Walenta, Evelyn, Itariu, Bianca, Prager, Gerhard, Hackl, Hubert, Stulnig, Thomas, Kratky, Dagmar, Rülicke, Thomas, Bogner-Strauss, Juliane G.

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Genetic deletion of MMP12 ameliorates cardiometabolic disease by improving insulin sensitivity, systemic inflammation, and atherosclerotic features in mice von Amor, Melina, Bianco, Valentina, Buerger, Martin, Lechleitner, Margarete, Vujić, Nemanja, Dobrijević, Anja, Akhmetshina, Alena, Pirchheim, Anita, Schwarz, Birgit, Pessentheiner, Ariane R, Baumgartner, Franziska, Rampitsch, Katharina, Schauer, Silvia, Klobučar, Iva, Degoricija, Vesna, Pregartner, Gudrun, Kummer, Daniel, Svecla, Monika, Sommer, Gerhard, Kolb, Dagmar, Holzapfel, Gerhard A, Hoefler, Gerald, Frank, Saša, Norata, Giuseppe Danilo, Kratky, Dagmar

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Glycocalyx engineering with heparan sulfate mimetics attenuates Wnt activity during adipogenesis to promote glucose uptake and metabolism von Trieger, Greg W., Pessentheiner, Ariane R., Purcell, Sean C., Green, Courtney R., DeForest, Natalie, Willert, Karl, Majithia, Amit R., Metallo, Christian M., Godula, Kamil, Gordts, Philip L.S.M.

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Critical role of the peroxisomal protein PEX16 in white adipocyte development and lipid homeostasis von Hofer, Dina C., Pessentheiner, Ariane R., Pelzmann, Helmut J., Schlager, Stefanie, Madreiter-Sokolowski, Corina T., Kolb, Dagmar, Eichmann, Thomas O., Rechberger, Gerald, Bilban, Martin, Graier, Wolfgang F., Kratky, Dagmar, Bogner-Strauss, Juliane G.

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N‐acetylaspartate availability is essential for juvenile survival on fat‐free diet and determines metabolic health von Hofer, Dina C., Zirkovits, Gabriel, Pelzmann, Helmut J., Huber, Katharina, Pessentheiner, Ariane R., Xia, Wenmin, Uno, Kyosuke, Miyazaki, Toh, Kon, Kanta, Tsuneki, Hiroshi, Pendl, Tobias, Zoughbi, Wael Al, Madreiter‐Sokolowski, Corina T., Trausinger, Gert, Abdellatif, Mahmoud, Schoiswohl, Gabriele, Schreiber, Renate, Eisenberg, Tobias, Magnes, Christoph, Sedej, Simon, Eckhardt, Matthias, Sasahara, Masakiyo, Sasaoka, Toshiyasu, Nitta, Atsumi, Hoefler, Gerald, Graier, Wolfgang F., Kratky, Dagmar, Auwerx, Johan, Bogner‐Strauss, Juliane G.

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α/β-hydrolase domain containing protein 15 (ABHD15)--an adipogenic protein protecting from apoptosis von Walenta, Evelyn, Pessentheiner, Ariane R, Pelzmann, Helmut J, Deutsch, Alexander, Goeritzer, Madeleine, Kratky, Dagmar, Hackl, Hubert, Oh, Da Young, Prokesch, Andreas, Bogner-Strauss, Juliane G

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Impaired mitophagy in Sanfilippo a mice causes hypertriglyceridemia and brown adipose tissue activation von Tillo, Miguel, Lamanna, William C., Dwyer, Chrissa A., Sandoval, Daniel R., Pessentheiner, Ariane R., Al-Azzam, Norah, Sarrazin, Stéphane, Gonzales, Jon C., Kan, Shih-Hsin, Andreyev, Alexander Y., Schultheis, Nicholas, Thacker, Bryan E., Glass, Charles A., Dickson, Patricia I., Wang, Raymond Y., Selleck, Scott B., Esko, Jeffrey D., Gordts, Philip L.S.M.

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Abstract 13528: Interventional Hepatic ApoC-III Knockdown Improves Atherosclerotic Plaque Stability and Remodeling via Lowering Remnant Lipoproteins von Gordts, Philip, Ramms, Bastian, Pessentheiner, Ariane, Sun, Xiaoli, Ducasa, Gloria M, Tsimikas, Sam, Witztum, Joseph L

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NAT8L (N-Acetyltransferase 8-Like) Accelerates Lipid Turnover and Increases Energy Expenditure in Brown Adipocytes von Pessentheiner, Ariane R., Pelzmann, Helmut J., Walenta, Evelyn, Schweiger, Martina, Groschner, Lukas N., Graier, Wolfgang F., Kolb, Dagmar, Uno, Kyosuke, Miyazaki, Toh, Nitta, Atsumi, Rieder, Dietmar, Prokesch, Andreas, Bogner-Strauss, Juliane G.

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