Determination of the Pharmacokinetics and Pharmacodynamics of Isoniazid, Rifampicin, Pyrazinamide and Ethambutol in a Cross-Over Cynomolgus Macaque Model of Mycobacterium tuberculo... von Sibley, Laura, White, Andrew D, Sarfas, Charlotte, Gullick, Jennie, Gleeson, Fergus, Lanni, Faye, Clark, Simon, Rayner, Emma, Ferrer-Bazaga, Santiago, Ortega-Muro, Fatima, Alameda, Laura, Rullas, Joaquin, Sousa, Veronica, Martinez, Marisa, Angulo-Barturen, Inigo, Garcia, Adolfo, Vaquero, Juan José, Pertinez, Henry E, Davies, Geraint, Dennis, Mike, Williams, Ann, Sharpe, Sally

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High Intrapulmonary Rifampicin and Isoniazid Concentrations Are Associated With Rapid Sputum Bacillary Clearance in Patients With Pulmonary Tuberculosis von McCallum, Andrew D, Pertinez, Henry E, Chirambo, Aaron P, Sheha, Irene, Chasweka, Madalitso, Malamba, Rose, Shani, Doris, Chitani, Alex, Mallewa, Jane E, Meghji, Jamilah Z, Ghany, Jehan F, Corbett, Elizabeth L, Gordon, Stephen B, Davies, Geraint R, Khoo, Saye H, Sloan, Derek J, Mwandumba, Henry C

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Intrapulmonary Pharmacokinetics of First-line Anti-tuberculosis Drugs in Malawian Patients With Tuberculosis von McCallum, Andrew D, Pertinez, Henry E, Else, Laura J, Dilly-Penchala, Sujan, Chirambo, Aaron P, Sheha, Irene, Chasweka, Madalitso, Chitani, Alex, Malamba, Rose D, Meghji, Jamilah Z, Gordon, Stephen B, Davies, Geraint R, Khoo, Saye H, Sloan, Derek J, Mwandumba, Henry C

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Pharmacokinetic-Pharmacodynamic Modeling of Alpha Interferon Response Induced by a Toll-Like 7 Receptor Agonist in Mice von BENSON, Neil, DE JONGH, Joost, DUCKWORTH, Jonathan D, JONES, Hannah M, PERTINEZ, Henry E, RAWAL, Jaiessh K, VAN STEEG, Tamara J, VAN DER GRAAF, Piet H

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High Intrapulmonary Rifampicin and Isoniazid Concentrations Are Associated With Rapid Sputum Bacillary Clearance in Patients With Pulmonary Tuberculosis von McCallum, Andrew D, Pertinez, Henry E, Chirambo, Aaron P, Sheha, Irene, Chasweka, Madalitso, Malamba, Rose, Shani, Doris, Chitani, Alex, Mallewa, Jane E, Meghji, Jamilah Z, Ghany, Jehan F, Corbett, Elizabeth L, Gordon, Stephen B, Davies, Geraint R, Khoo, Saye H, Sloan, Derek J, Mwandumba, Henry C

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Intrapulmonary Pharmacokinetics of First-line Anti-tuberculosis Drugs in Malawian Patients With Tuberculosis von McCallum, Andrew D., Pertinez, Henry E., Else, Laura J., Dilly-Penchala, Sujan, Chirambo, Aaron P., Sheha, Irene, Chasweka, Madalitso, Chitani, Alex, Malamba, Rose D., Meghji, Jamilah Z., Gordon, Stephen B., Davies, Geraint R., Khoo, Saye H., Sloan, Derek J., Mwandumba, Henry C.

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Determination of the Pharmacokinetics and Pharmacodynamics of Isoniazid, Rifampicin, Pyrazinamide and Ethambutol in a Cross-Over Cynomolgus Macaque Model of IMycobacterium tubercul... von Sibley, Laura, White, Andrew D, Sarfas, Charlotte, Gullick, Jennie, Gleeson, Fergus, Lanni, Faye, Clark, Simon, Rayner, Emma, Ferrer-Bazaga, Santiago, Ortega-Muro, Fatima, Alameda, Laura, Rullas, Joaquin, Sousa, Veronica, Ma, Angulo-Barturen, Inigo, Garcia, Adolfo, Vaquero, Juan José, Pe, Davies, Geraint, Dennis, Mike, Williams, Ann, Sharpe, Sally

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Efficacy and Safety of High-Dose Rifampin in Pulmonary Tuberculosis. A Randomized Controlled Trial von Velásquez, Gustavo E, Brooks, Meredith B, Coit, Julia M, Pertinez, Henry, Vargas Vásquez, Dante, Sánchez Garavito, Epifanio, Calderón, Roger I, Jiménez, Judith, Tintaya, Karen, Peloquin, Charles A, Osso, Elna, Tierney, Dylan B, Seung, Kwonjune J, Lecca, Leonid, Davies, Geraint R, Mitnick, Carole D

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An Open Label, Adaptive, Phase 1 Trial of High‐Dose Oral Nitazoxanide in Healthy Volunteers: An Antiviral Candidate for SARS‐CoV‐2 von Walker, Lauren E., FitzGerald, Richard, Saunders, Geoffrey, Lyon, Rebecca, Fisher, Michael, Martin, Karen, Eberhart, Izabela, Woods, Christie, Ewings, Sean, Hale, Colin, Rajoli, Rajith K. R., Else, Laura, Dilly‐Penchala, Sujan, Amara, Alieu, Lalloo, David G., Jacobs, Michael, Pertinez, Henry, Hatchard, Parys, Waugh, Robert, Lawrence, Megan, Johnson, Lucy, Fines, Keira, Reynolds, Helen, Rowland, Timothy, Crook, Rebecca, Okenyi, Emmanuel, Byrne, Kelly, Mozgunov, Pavel, Jaki, Thomas, Khoo, Saye, Owen, Andrew, Griffiths, Gareth, Fletcher, Thomas E.

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ERS Special Article.Efficacy and Safety of High-Dose Rifampin in Pulmonary Tuberculosis. A Randomized Controlled Trial von Velásquez, Gustavo E., Brooks, Meredith B., Coit, Julia M., Pertinez, Henry, Vargas Vásquez, Dante, Sánchez Garavito, Epifanio, Calderón, Roger I., Jiménez, Judith, Tintaya, Karen, Peloquin, Charles A., Osso, Elna, Tierney, Dylan B., Seung, Kwonjune J., Lecca, Leonid, Davies, Geraint R., Mitnick, Carole D.

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Assessment of treatment response by colony forming units, time to culture positivity and the molecular bacterial load assay compared in a mouse tuberculosis model von de Knegt, Gerjo J, Dickinson, Laura, Pertinez, Henry, Evangelopoulos, Dimitrios, McHugh, Timothy D, Bakker-Woudenberg, Irma A.J.M, Davies, Gerry R, de Steenwinkel, Jurriaan E.M

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FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2 von Brevini, Teresa, Maes, Mailis, Webb, Gwilym J, John, Binu V, Fuchs, Claudia D, Buescher, Gustav, Wang, Lu, Griffiths, Chelsea, Brown, Marnie L, Scott, William E, Pereyra-Gerber, Pehuén, Gelson, William TH, Brown, Stephanie, Dillon, Scott, Muraro, Daniele, Sharp, Jo, Neary, Megan, Box, Helen, Tatham, Lee, Stewart, James, Curley, Paul, Pertinez, Henry, Forrest, Sally, Mlcochova, Petra, Varankar, Sagar S, Darvish-Damavandi, Mahnaz, Mulcahy, Victoria L, Kuc, Rhoda E, Williams, Thomas L, Heslop, James A, Rossetti, Davide, Tysoe, Olivia C, Galanakis, Vasileios, Vila-Gonzalez, Marta, Crozier, Thomas WM, Bargehr, Johannes, Sinha, Sanjay, Upponi, Sara S, Fear, Corrina, Swift, Lisa, Saeb-Parsy, Kourosh, Davies, Susan E, Wester, Axel, Hagström, Hannes, Melum, Espen, Clements, Darran, Humphreys, Peter, Herriott, Jo, Kijak, Edyta, Cox, Helen, Bramwell, Chloe, Valentijn, Anthony, Illingworth, Christopher JR, UK-PBC Consortium, Dahman, Bassam, Bastaich, Dustin R, Ferreira, Raphaella D, Marjot, Thomas, Barnes, Eleanor, Moon, Andrew M, Barritt, Alfred S, Gupta, Ravindra K, Baker, Stephen, Davenport, Anthony P, Corbett, Gareth, Gorgoulis, Vassilis G, Buczacki, Simon JA, Lee, Joo-Hyeon, Matheson, Nicholas J, Trauner, Michael, Fisher, Andrew J, Gibbs, Paul, Butler, Andrew J, Watson, Christopher JE, Mells, George F, Dougan, Gordon, Owen, Andrew, Lohse, Ansgar W, Vallier, Ludovic, Sampaziotis, Fotios

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An Open Label, Adaptive, Phase 1 Trial of High-Dose Oral Nitazoxanide in Healthy Volunteers: An Antiviral Candidate for SARS-CoV-2 von Walker, Lauren E, FitzGerald, Richard, Saunders, Geoffrey, Lyon, Rebecca, Fisher, Michael, Martin, Karen, Eberhart, Izabela, Woods, Christie, Ewings, Sean, Hale, Colin, Rajoli, Rajith KR, Else, Laura, Dilly-Penchala, Sujan, Amara, Alieu, Lalloo, David G, Jacobs, Michael, Pertinez, Henry, Hatchard, Parys, Waugh, Robert, Lawrence, Megan, Johnson, Lucy, Fines, Keira, Reynolds, Helen, Rowland, Timothy, Crook, Rebecca, Okenyi, Emmanuel, Byrne, Kelly, Mozgunov, Pavel, Jaki, Thomas, Khoo, Saye, Owen, Andrew, Griffiths, Gareth, Fletcher, Thomas E, AGILE platform

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FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2 von Brevini, Teresa, Maes, Mailis, Webb, Gwilym J, John, Binu V, Fuchs, Claudia D, Buescher, Gustav, Wang, Lu, Griffiths, Chelsea, Brown, Marnie L, Scott, William E, Pereyra-Gerber, Pehuén, Gelson, William TH, Brown, Stephanie, Dillon, Scott, Muraro, Daniele, Sharp, Jo, Neary, Megan, Box, Helen, Tatham, Lee, Stewart, James, Curley, Paul, Pertinez, Henry, Forrest, Sally, Mlcochova, Petra, Varankar, Sagar S, Darvish-Damavandi, Mahnaz, Mulcahy, Victoria L, Kuc, Rhoda E, Williams, Thomas L, Heslop, James A, Rossetti, Davide, Tysoe, Olivia C, Galanakis, Vasileios, Vila-Gonzalez, Marta, Crozier, Thomas WM, Bargehr, Johannes, Sinha, Sanjay, Upponi, Sara S, Fear, Corrina, Swift, Lisa, Saeb-Parsy, Kourosh, Davies, Susan E, Wester, Axel, Hagström, Hannes, Melum, Espen, Clements, Darran, Humphreys, Peter, Herriott, Jo, Kijak, Edyta, Cox, Helen, Bramwell, Chloe, Valentijn, Anthony, Illingworth, Christopher JR, UK-PBC Consortium, Dahman, Bassam, Bastaich, Dustin R, Ferreira, Raphaella D, Marjot, Thomas, Barnes, Eleanor, Moon, Andrew M, Barritt, Alfred S, Gupta, Ravindra K, Baker, Stephen, Davenport, Anthony P, Corbett, Gareth, Gorgoulis, Vassilis G, Buczacki, Simon JA, Lee, Joo-Hyeon, Matheson, Nicholas J, Trauner, Michael, Fisher, Andrew J, Gibbs, Paul, Butler, Andrew J, Watson, Christopher JE, Mells, George F, Dougan, Gordon, Owen, Andrew, Lohse, Ansgar W, Vallier, Ludovic, Sampaziotis, Fotios

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An Open Label, Adaptive, Phase 1 Trial of High-Dose Oral Nitazoxanide in Healthy Volunteers: An Antiviral Candidate for SARS-CoV-2 von Walker, Lauren E, FitzGerald, Richard, Saunders, Geoffrey, Lyon, Rebecca, Fisher, Michael, Martin, Karen, Eberhart, Izabela, Woods, Christie, Ewings, Sean, Hale, Colin, Rajoli, Rajith KR, Else, Laura, Dilly-Penchala, Sujan, Amara, Alieu, Lalloo, David G, Jacobs, Michael, Pertinez, Henry, Hatchard, Parys, Waugh, Robert, Lawrence, Megan, Johnson, Lucy, Fines, Keira, Reynolds, Helen, Rowland, Timothy, Crook, Rebecca, Okenyi, Emmanuel, Byrne, Kelly, Mozgunov, Pavel, Jaki, Thomas, Khoo, Saye, Owen, Andrew, Griffiths, Gareth, Fletcher, Thomas E, AGILE platform

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