Beyond Kinase Activity: ERK5 Nucleo-Cytoplasmic Shuttling as a Novel Target for Anticancer Therapy von Tubita, Alessandro, Lombardi, Zoe, Tusa, Ignazia, Dello Sbarba, Persio, Rovida, Elisabetta

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Inhibition of ERK5 Elicits Cellular Senescence in Melanoma via the Cyclin-Dependent Kinase Inhibitor p21 von Tubita, Alessandro, Lombardi, Zoe, Tusa, Ignazia, Lazzeretti, Azzurra, Sgrignani, Giovanna, Papini, Dimitri, Menconi, Alessio, Gagliardi, Sinforosa, Lulli, Matteo, Dello Sbarba, Persio, Esparís-Ogando, Azucena, Pandiella, Atanasio, Stecca, Barbara, Rovida, Elisabetta

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The Hedgehog-GLI Pathway Regulates MEK5-ERK5 Expression and Activation in Melanoma Cells von Tusa, Ignazia, Gagliardi, Sinforosa, Tubita, Alessandro, Pandolfi, Silvia, Menconi, Alessio, Lulli, Matteo, Dello Sbarba, Persio, Stecca, Barbara, Rovida, Elisabetta

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Prostaglandin E2 transactivates the colony‐stimulating factor‐1 receptor and synergizes with colony‐stimulating factor‐1 in the induction of macrophage migration via the mitogen‐ac... von Digiacomo, Graziana, Ziche, Marina, Dello Sbarba, Persio, Donnini, Sandra, Rovida, Elisabetta

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The mitogen-activated protein kinase ERK5 regulates the development and growth of hepatocellular carcinoma von Rovida, Elisabetta, Di Maira, Giovanni, Tusa, Ignazia, Cannito, Stefania, Paternostro, Claudia, Navari, Nadia, Vivoli, Elisa, Deng, Xianming, Gray, Nathanael S, Esparís-Ogando, Azucena, David, Ezio, Pandiella, Atanasio, Dello Sbarba, Persio, Parola, Maurizio, Marra, Fabio

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The metabolically-modulated stem cell niche: a dynamic scenario regulating cancer cell phenotype and resistance to therapy von Rovida, Elisabetta, Peppicelli, Silvia, Bono, Silvia, Bianchini, Francesca, Tusa, Ignazia, Cheloni, Giulia, Marzi, Ilaria, Cipolleschi, Maria Grazia, Calorini, Lido, Sbarba, Persio Dello

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Glutamine Availability Controls BCR/Abl Protein Expression and Functional Phenotype of Chronic Myeloid Leukemia Cells Endowed with Stem/Progenitor Cell Potential von Poteti, Martina, Menegazzi, Giulio, Peppicelli, Silvia, Tusa, Ignazia, Cheloni, Giulia, Silvano, Angela, Mancini, Caterina, Biagioni, Alessio, Tubita, Alessandro, Mazure, Nathalie M., Lulli, Matteo, Rovida, Elisabetta, Dello Sbarba, Persio

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In vivo monitoring of leukemia-niche interactions in a zebrafish xenograft model von Arner, Anja, Ettinger, Andreas, Blaser, Bradley Wayne, Schmid, Bettina, Jeremias, Irmela, Rostam, Nadia, Binder-Blaser, Vera

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Cancer stemness and progression: mitochondria on the stage von Chiarugi, Paola, Dello Sbarba, Persio

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An advanced preclinical mouse model for acute myeloid leukemia using patients' cells of various genetic subgroups and in vivo bioluminescence imaging von Vick, Binje, Rothenberg, Maja, Sandhöfer, Nadine, Carlet, Michela, Finkenzeller, Cornelia, Krupka, Christina, Grunert, Michaela, Trumpp, Andreas, Corbacioglu, Selim, Ebinger, Martin, André, Maya C, Hiddemann, Wolfgang, Schneider, Stephanie, Subklewe, Marion, Metzeler, Klaus H, Spiekermann, Karsten, Jeremias, Irmela

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Adaptive phenotypic modulations lead to therapy resistance in chronic myeloid leukemia cells von Baykal-Köse, Seda, Acikgoz, Eda, Yavuz, Ahmet Sinan, Gönül Geyik, Öykü, Ateş, Halil, Sezerman, Osman Uğur, Özsan, Güner Hayri, Yüce, Zeynep

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Methylation pattern analysis in prostate cancer tissue: identification of biomarkers using an MS-MLPA approach von Gurioli, Giorgia, Salvi, Samanta, Martignano, Filippo, Foca, Flavia, Gunelli, Roberta, Costantini, Matteo, Cicchetti, Giacomo, De Giorgi, Ugo, Sbarba, Persio Dello, Calistri, Daniele, Casadio, Valentina

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Different BCR/Abl protein suppression patterns as a converging trait of chronic myeloid leukemia cell adaptation to energy restriction von Bono, Silvia, Lulli, Matteo, D'Agostino, Vito Giuseppe, Di Gesualdo, Federico, Loffredo, Rosa, Cipolleschi, Maria Grazia, Provenzani, Alessandro, Rovida, Elisabetta, Dello Sbarba, Persio

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Combined inhibition of BCR-ABL1 and the proteasome as a potential novel therapeutic approach in BCR-ABL positive acute lymphoblastic leukemia von Maletzke, Saskia, Salimi, Azam, Vieri, Margherita, Schroeder, Kema Marlen, Schemionek, Mirle, Masouleh, Behzad Kharabi, Brümmendorf, Tim H, Koschmieder, Steffen, Appelmann, Iris

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Hypoxia-resistant profile implies vulnerability of cancer stem cells to physiological agents, which suggests new therapeutic targets von Grazia Cipolleschi, Maria, Marzi, Ilaria, Santini, Roberta, Fredducci, David, Cristina Vinci, Maria, D'Amico, Massimo, Rovida, Elisabetta, Stivarou, Theodora, Torre, Eugenio, Dello Sbarba, Persio, Stecca, Barbara, Olivotto, Massimo

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Hypoxia selects bortezomib-resistant stem cells of chronic myeloid leukemia von Tanturli, Michele, Giuntoli, Serena, Barbetti, Valentina, Rovida, Elisabetta, Dello Sbarba, Persio

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Combination of curaxin and tyrosine kinase inhibitors display enhanced killing of primitive Chronic Myeloid Leukaemia cells von Pearson, Stella, Whetton, Anthony D, Pierce, Andrew

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The Leukemic Stem Cell Niche: Adaptation to “Hypoxia” versus Oncogene Addiction von Dello Sbarba, Persio, Rovida, Elisabetta, Mazure, Nathalie M., Masala, Erico, Bono, Silvia, Poteti, Martina, Cheloni, Giulia, Lulli, Matteo

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Acriflavine targets oncogenic STAT5 signaling in myeloid leukemia cells von Hallal, Rawan, Nehme, Rawan, Brachet‐Botineau, Marie, Nehme, Ali, Dakik, Hassan, Deynoux, Margaux, Dello Sbarba, Persio, Levern, Yves, Zibara, Kazem, Gouilleux, Fabrice, Mazurier, Frédéric

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The involvement of a Nanog, Klf4 and c-Myc transcriptional circuitry in the intertwining between neoplastic progression and reprogramming von Marzi, Ilaria, Cipolleschi, Maria Grazia, D'Amico, Massimo, Stivarou, Theodora, Rovida, Elisabetta, Vinci, Maria Cristina, Pandolfi, Silvia, Dello Sbarba, Persio, Stecca, Barbara, Olivotto, Massimo

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