PI3K inhibitors are finally coming of age von Vanhaesebroeck, Bart, Perry, Matthew W. D., Brown, Jennifer R., André, Fabrice, Okkenhaug, Klaus

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Design, Synthesis, and Biological Evaluation of MEK PROTACs von Vollmer, Stefan, Cunoosamy, Danen, Lv, Huafei, Feng, Huanxi, Li, Xia, Nan, Ziyang, Yang, Wenzhen, Perry, Matthew W. D

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Author Correction: PI3K inhibitors are finally coming of age von Vanhaesebroeck, Bart, Perry, Matthew W. D., Brown, Jennifer R., André, Fabrice, Okkenhaug, Klaus

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Impact of Stereospecific Intramolecular Hydrogen Bonding on Cell Permeability and Physicochemical Properties von Over, Björn, McCarren, Patrick, Artursson, Per, Foley, Michael, Giordanetto, Fabrizio, Grönberg, Gunnar, Hilgendorf, Constanze, Lee, Maurice D, Matsson, Pär, Muncipinto, Giovanni, Pellisson, Mélanie, Perry, Matthew W. D, Svensson, Richard, Duvall, Jeremy R, Kihlberg, Jan

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Structural and conformational determinants of macrocycle cell permeability von Over, Björn, Matsson, Pär, Tyrchan, Christian, Artursson, Per, Doak, Bradley C, Foley, Michael A, Hilgendorf, Constanze, Johnston, Stephen E, Lee, Maurice D, Lewis, Richard J, McCarren, Patrick, Muncipinto, Giovanni, Norinder, Ulf, Perry, Matthew W D, Duvall, Jeremy R, Kihlberg, Jan

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Evolution of PI3Kγ and δ Inhibitors for Inflammatory and Autoimmune Diseases von Perry, Matthew W. D, Abdulai, Raolat, Mogemark, Mickael, Petersen, Jens, Thomas, Matthew J, Valastro, Barbara, Westin Eriksson, Annika

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A class of highly selective inhibitors bind to an active state of PI3Kγ von Gangadhara, Gangadhara, Dahl, Göran, Bohnacker, Thomas, Rae, Rebecca, Gunnarsson, Jenny, Blaho, Stefan, Öster, Linda, Lindmark, Helena, Karabelas, Kostas, Pemberton, Nils, Tyrchan, Christian, Mogemark, Mickael, Wymann, Matthias P., Williams, Roger L., Perry, Matthew W. D., Papavoine, Tineke, Petersen, Jens

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Discovery of Highly Isoform Selective Orally Bioavailable Phosphoinositide 3‑Kinase (PI3K)‑γ Inhibitors von Pemberton, Nils, Mogemark, Mickael, Arlbrandt, Susanne, Bold, Peter, Cox, Rhona J, Gardelli, Cristina, Holden, Neil S, Karabelas, Kostas, Karlsson, Johan, Lever, Sarah, Li, Xueshan, Lindmark, Helena, Norberg, Monica, Perry, Matthew W. D, Petersen, Jens, Rodrigo Blomqvist, Sandra, Thomas, Matthew, Tyrchan, Christian, Westin Eriksson, Annika, Zlatoidsky, Pavol, Öster, Linda

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Scaffold-hopping with zwitterionic CCR3 antagonists: Identification and optimisation of a series with good potency and pharmacokinetics leading to the discovery of AZ12436092 von Bahl, Ash, Barton, Patrick, Bowers, Keith, Caffrey, Moya V., Denton, Rebecca, Gilmour, Peter, Hawley, Shaun, Linannen, Tero, Luckhurst, Christopher A., Mochel, Tobias, Perry, Matthew W.D., Riley, Robert J., Roe, Emma, Springthorpe, Brian, Stein, Linda, Webborn, Peter

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Discovery of AZD8154, a Dual PI3Kγδ Inhibitor for the Treatment of Asthma von Perry, Matthew W. D, Björhall, Karin, Bold, Peter, Brűlls, Mikael, Börjesson, Ulf, Carlsson, Johan, Chang, Hui-Fang Amy, Chen, Yunhua, Eriksson, Anders, Fihn, Britt-Marie, Fransson, Rebecca, Fredlund, Linda, Ge, Hongbin, Huang, Haijuan, Karabelas, Kostas, Lamm Bergström, Eva, Lever, Sarah, Lindmark, Helena, Mogemark, Mickael, Nikitidis, Antonios, Palmgren, Anna-Pia, Pemberton, Nils, Petersen, Jens, Rodrigo Blomqvist, Mio, Smith, Reed W, Thomas, Matthew J, Ullah, Victoria, Tyrchan, Christian, Wennberg, Tiiu, Westin Eriksson, Annika, Yang, Wenzhen, Zhao, Shuchun, Öster, Linda

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Identification of Phosphate-Containing Compounds as New Inhibitors of 14-3-3/c-Abl Protein–Protein Interaction von Iralde-Lorente, Leire, Tassone, Giusy, Clementi, Letizia, Franci, Lorenzo, Munier, Claire C, Cau, Ylenia, Mori, Mattia, Chiariello, Mario, Angelucci, Adriano, Perry, Matthew W. D, Pozzi, Cecilia, Mangani, Stefano, Botta, Maurizio

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Design and Synthesis of Soluble and Cell-Permeable PI3Kδ Inhibitors for Long-Acting Inhaled Administration von Perry, Matthew W. D, Björhall, Karin, Bonn, Britta, Carlsson, Johan, Chen, Yunhua, Eriksson, Anders, Fredlund, Linda, Hao, Hai’e, Holden, Neil S, Karabelas, Kostas, Lindmark, Helena, Liu, Feifei, Pemberton, Nils, Petersen, Jens, Rodrigo Blomqvist, Sandra, Smith, Reed W, Svensson, Tor, Terstiege, Ina, Tyrchan, Christian, Yang, Wenzhen, Zhao, Shuchun, Öster, Linda

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Localization of cerebral activity during simple singing von Perry, David W, Zatorre, Robert J, Petrides, Michael, Alivisatos, Bessie, Meyer, Ernst, Evans, Alan C

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14-3-3 modulation of the inflammatory response von Munier, Claire C., Ottmann, Christian, Perry, Matthew W.D.

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Spiro-fused Pyrrolidine, Piperidine, and Oxindole Scaffolds from Lactams von Hirschhäuser, Christoph, Parker, Jeremy S, Perry, Matthew W. D, Haddow, Mairi F, Gallagher, Timothy

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Surprising lipophilicity observations identify unexpected conformational effects von Perry, Matthew W.D., Börjesson, Ulf, Nikitidis, Antonios, Tyrchan, Christian

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Glucocorticoid receptor Thr524 phosphorylation by MINK1 induces interactions with 14-3-3 protein regulators von Munier, Claire C., De Maria, Leonardo, Edman, Karl, Gunnarsson, Anders, Longo, Marianna, MacKintosh, Carol, Patel, Saleha, Snijder, Arjan, Wissler, Lisa, Brunsveld, Luc, Ottmann, Christian, Perry, Matthew W.D.

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Designing Selective Drug-like Molecular Glues for the Glucocorticoid Receptor/14-3‑3 Protein–Protein Interaction von Pallesen, Jakob S., Munier, Claire C., Bosica, Francesco, Andrei, Sebastian A., Edman, Karl, Gunnarsson, Anders, La Sala, Giuseppina, Putra, Okky Dwichandra, Srdanović, Sonja, Wilson, Andrew J., Wissler, Lisa, Ottmann, Christian, Perry, Matthew W. D., O’Mahony, Gavin

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Localization of cerebral activity during simple singing von Perry, David W, Zatorre, Robert J, Petrides, Michael, Alivisatos, Bessie, Meyer, Ernst, Evans, Alan C

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Manifestations of depression in people with intellectual disability von Marston, G. M., Perry, D. W., Roy, A.

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