PI3K inhibitors are finally coming of age von Vanhaesebroeck, Bart, Perry, Matthew W. D., Brown, Jennifer R., André, Fabrice, Okkenhaug, Klaus

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hERG K(+) channels: structure, function, and clinical significance von Vandenberg, Jamie I, Perry, Matthew D, Perrin, Mark J, Mann, Stefan A, Ke, Ying, Hill, Adam P

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Design, Synthesis, and Biological Evaluation of MEK PROTACs von Vollmer, Stefan, Cunoosamy, Danen, Lv, Huafei, Feng, Huanxi, Li, Xia, Nan, Ziyang, Yang, Wenzhen, Perry, Matthew W. D

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Author Correction: PI3K inhibitors are finally coming of age von Vanhaesebroeck, Bart, Perry, Matthew W. D., Brown, Jennifer R., André, Fabrice, Okkenhaug, Klaus

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Impact of Stereospecific Intramolecular Hydrogen Bonding on Cell Permeability and Physicochemical Properties von Over, Björn, McCarren, Patrick, Artursson, Per, Foley, Michael, Giordanetto, Fabrizio, Grönberg, Gunnar, Hilgendorf, Constanze, Lee, Maurice D, Matsson, Pär, Muncipinto, Giovanni, Pellisson, Mélanie, Perry, Matthew W. D, Svensson, Richard, Duvall, Jeremy R, Kihlberg, Jan

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Development of a robust induced pluripotent stem cell atrial cardiomyocyte differentiation protocol to model atrial arrhythmia von Thorpe, Jordan, Perry, Matthew D, Contreras, Osvaldo, Hurley, Emily, Parker, George, Harvey, Richard P, Hill, Adam P, Vandenberg, Jamie I

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Evolution of PI3Kγ and δ Inhibitors for Inflammatory and Autoimmune Diseases von Perry, Matthew W. D, Abdulai, Raolat, Mogemark, Mickael, Petersen, Jens, Thomas, Matthew J, Valastro, Barbara, Westin Eriksson, Annika

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Multiple Interactions between Cytoplasmic Domains Regulate Slow Deactivation of Kv11.1 Channels von Ng, Chai Ann, Phan, Kevin, Hill, Adam P., Vandenberg, Jamie I., Perry, Matthew D.

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Getting to the heart of hERG K+ channel gating von Perry, Matthew D., Ng, Chai‐Ann, Mann, Stefan A., Sadrieh, Arash, Imtiaz, Mohammad, Hill, Adam P., Vandenberg, Jamie I.

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The S4-S5 linker acts as a signal integrator for HERG K+ channel activation and deactivation gating von Ng, Chai Ann, Perry, Matthew D, Tan, Peter S, Hill, Adam P, Kuchel, Philip W, Vandenberg, Jamie I

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Structural and conformational determinants of macrocycle cell permeability von Over, Björn, Matsson, Pär, Tyrchan, Christian, Artursson, Per, Doak, Bradley C, Foley, Michael A, Hilgendorf, Constanze, Johnston, Stephen E, Lee, Maurice D, Lewis, Richard J, McCarren, Patrick, Muncipinto, Giovanni, Norinder, Ulf, Perry, Matthew W D, Duvall, Jeremy R, Kihlberg, Jan

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TECRL: connecting sequence to consequence for a new sudden cardiac death gene von Perry, Matthew D, Vandenberg, Jamie I

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The S1 helix critically regulates the finely tuned gating of Kv11.1 channels von Phan, Kevin, Ng, Chai Ann, David, Erikka, Shishmarev, Dmitry, Kuchel, Philip W., Vandenberg, Jamie I., Perry, Matthew D.

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The N-terminal tail of hERG contains an amphipathic α-helix that regulates channel deactivation von Ng, Chai Ann, Hunter, Mark J, Perry, Matthew D, Mobli, Mehdi, Ke, Ying, Kuchel, Philip W, King, Glenn F, Stock, Daniela, Vandenberg, Jamie I

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Voltage-sensing domain mode shift is coupled to the activation gate by the N-terminal tail of hERG channels von Tan, Peter S, Perry, Matthew D, Ng, Chai Ann, Vandenberg, Jamie I, Hill, Adam P

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A class of highly selective inhibitors bind to an active state of PI3Kγ von Gangadhara, Gangadhara, Dahl, Göran, Bohnacker, Thomas, Rae, Rebecca, Gunnarsson, Jenny, Blaho, Stefan, Öster, Linda, Lindmark, Helena, Karabelas, Kostas, Pemberton, Nils, Tyrchan, Christian, Mogemark, Mickael, Wymann, Matthias P., Williams, Roger L., Perry, Matthew W. D., Papavoine, Tineke, Petersen, Jens

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Discovery of Highly Isoform Selective Orally Bioavailable Phosphoinositide 3‑Kinase (PI3K)‑γ Inhibitors von Pemberton, Nils, Mogemark, Mickael, Arlbrandt, Susanne, Bold, Peter, Cox, Rhona J, Gardelli, Cristina, Holden, Neil S, Karabelas, Kostas, Karlsson, Johan, Lever, Sarah, Li, Xueshan, Lindmark, Helena, Norberg, Monica, Perry, Matthew W. D, Petersen, Jens, Rodrigo Blomqvist, Sandra, Thomas, Matthew, Tyrchan, Christian, Westin Eriksson, Annika, Zlatoidsky, Pavol, Öster, Linda

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Steady-state modulation of voltage-gated K+ channels in rat arterial smooth muscle by cyclic AMP-dependent protein kinase and protein phosphatase 2B von Brignell, Jennifer L, Perry, Matthew D, Nelson, Carl P, Willets, Jonathon M, Challiss, R A John, Davies, Noel W

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Scaffold-hopping with zwitterionic CCR3 antagonists: Identification and optimisation of a series with good potency and pharmacokinetics leading to the discovery of AZ12436092 von Bahl, Ash, Barton, Patrick, Bowers, Keith, Caffrey, Moya V., Denton, Rebecca, Gilmour, Peter, Hawley, Shaun, Linannen, Tero, Luckhurst, Christopher A., Mochel, Tobias, Perry, Matthew W.D., Riley, Robert J., Roe, Emma, Springthorpe, Brian, Stein, Linda, Webborn, Peter

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Discovery of AZD8154, a Dual PI3Kγδ Inhibitor for the Treatment of Asthma von Perry, Matthew W. D, Björhall, Karin, Bold, Peter, Brűlls, Mikael, Börjesson, Ulf, Carlsson, Johan, Chang, Hui-Fang Amy, Chen, Yunhua, Eriksson, Anders, Fihn, Britt-Marie, Fransson, Rebecca, Fredlund, Linda, Ge, Hongbin, Huang, Haijuan, Karabelas, Kostas, Lamm Bergström, Eva, Lever, Sarah, Lindmark, Helena, Mogemark, Mickael, Nikitidis, Antonios, Palmgren, Anna-Pia, Pemberton, Nils, Petersen, Jens, Rodrigo Blomqvist, Mio, Smith, Reed W, Thomas, Matthew J, Ullah, Victoria, Tyrchan, Christian, Wennberg, Tiiu, Westin Eriksson, Annika, Yang, Wenzhen, Zhao, Shuchun, Öster, Linda

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