Genome-wide association studies of asthma in population-based cohorts confirm known and suggested loci and identify an additional association near HLA von Ramasamy, Adaikalavan, Kuokkanen, Mikko, Vedantam, Sailaja, Gajdos, Zofia K, Couto Alves, Alexessander, Lyon, Helen N, Ferreira, Manuel A R, Strachan, David P, Zhao, Jing Hua, Abramson, Michael J, Brown, Matthew A, Coin, Lachlan, Dharmage, Shyamali C, Duffy, David L, Haahtela, Tari, Heath, Andrew C, Janson, Christer, Kähönen, Mika, Khaw, Kay-Tee, Laitinen, Jaana, Le Souef, Peter, Lehtimäki, Terho, Madden, Pamela A F, Marks, Guy B, Martin, Nicholas G, Matheson, Melanie C, Palmer, Cameron D, Palotie, Aarno, Pouta, Anneli, Robertson, Colin F, Viikari, Jorma, Widen, Elisabeth, Wjst, Matthias, Jarvis, Deborah L, Montgomery, Grant W, Thompson, Philip J, Wareham, Nick, Eriksson, Johan, Jousilahti, Pekka, Laitinen, Tarja, Pekkanen, Juha, Raitakari, Olli T, O'Connor, George T, Salomaa, Veikko, Jarvelin, Marjo-Riitta, Hirschhorn, Joel N

Volltext

Alterations in LMTK2, MSMB and HNF1B gene expression are associated with the development of prostate cancer von Harries, Lorna W, Perry, John R B, McCullagh, Paul, Crundwell, Malcolm

Volltext

Genome-wide identification of expression quantitative trait loci (eQTLs) in human heart von Koopmann, Tamara T, Adriaens, Michiel E, Moerland, Perry D, Marsman, Roos F, Westerveld, Margriet L, Lal, Sean, Zhang, Taifang, Simmons, Christine Q, Baczko, Istvan, dos Remedios, Cristobal, Bishopric, Nanette H, Varro, Andras, George, Jr, Alfred L, Lodder, Elisabeth M, Bezzina, Connie R

Volltext

Influence of genetic variation on plasma protein levels in older adults using a multi-analyte panel von Kim, Sungeun, Swaminathan, Shanker, Inlow, Mark, Risacher, Shannon L, Nho, Kwangsik, Shen, Li, Foroud, Tatiana M, Petersen, Ronald C, Aisen, Paul S, Soares, Holly, Toledo, Jon B, Shaw, Leslie M, Trojanowski, John Q, Weiner, Michael W, McDonald, Brenna C, Farlow, Martin R, Ghetti, Bernardino, Saykin, Andrew J

Volltext

An atlas of genetic correlations across human diseases and traits von Bulik-Sullivan, Brendan, Finucane, Hilary K, Anttila, Verneri, Gusev, Alexander, Day, Felix R, Loh, Po-Ru, Duncan, Laramie, Perry, John R B, Patterson, Nick, Robinson, Elise B, Daly, Mark J, Price, Alkes L, Neale, Benjamin M

Volltext

Puberty timing associated with diabetes, cardiovascular disease and also diverse health outcomes in men and women: the UK Biobank study von Day, Felix R, Elks, Cathy E, Murray, Anna, Ong, Ken K, Perry, John R.B.

Volltext

Partitioning heritability by functional annotation using genome-wide association summary statistics von Finucane, Hilary K, Bulik-Sullivan, Brendan, Gusev, Alexander, Trynka, Gosia, Reshef, Yakir, Loh, Po-Ru, Anttila, Verneri, Xu, Han, Zang, Chongzhi, Farh, Kyle, Ripke, Stephan, Day, Felix R, Purcell, Shaun, Stahl, Eli, Lindstrom, Sara, Perry, John R B, Okada, Yukinori, Raychaudhuri, Soumya, Daly, Mark J, Patterson, Nick, Neale, Benjamin M, Price, Alkes L

Volltext

Genetic predisposition to higher body mass index or type 2 diabetes and leukocyte telomere length in the Nurses' Health Study von Du, Mengmeng, Prescott, Jennifer, Cornelis, Marilyn C, Hankinson, Susan E, Giovannucci, Edward, Kraft, Peter, De Vivo, Immaculata

Volltext

Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index von Yang, Jian, Bakshi, Andrew, Zhu, Zhihong, Hemani, Gibran, Vinkhuyzen, Anna A E, Lee, Sang Hong, Robinson, Matthew R, Perry, John R B, Nolte, Ilja M, van Vliet-Ostaptchouk, Jana V, Snieder, Harold, Esko, Tonu, Milani, Lili, Mägi, Reedik, Metspalu, Andres, Hamsten, Anders, Magnusson, Patrik K E, Pedersen, Nancy L, Ingelsson, Erik, Soranzo, Nicole, Keller, Matthew C, Wray, Naomi R, Goddard, Michael E, Visscher, Peter M

Volltext

The CD94/NKG2A inhibitory receptor educates uterine NK cells to optimize pregnancy outcomes in humans and mice von Shreeve, Norman, Depierreux, Delphine, Hawkes, Delia, Traherne, James A., Sovio, Ulla, Huhn, Oisin, Jayaraman, Jyothi, Horowitz, Amir, Ghadially, Hormas, Perry, John R.B., Moffett, Ashley, Sled, John G., Sharkey, Andrew M., Colucci, Francesco

Volltext

Biomarkers for Type 2 Diabetes and Impaired Fasting Glucose Using a Nontargeted Metabolomics Approach von MENNI, Cristina, FAUMAN, Eric, WEI YUAN, MILBURN, Mike, PALMER, Colin N. A, FRAYLING, Timothy M, TRIMMER, Jeff, BELL, Jordana T, GIEGER, Christian, MOHNEY, Rob P, BROSNAN, Mary Julia, SUHRE, Karsten, ERTE, Idil, SORANZO, Nicole, SPECTOR, Tim D, PERRY, John R. B, KASTENMÜLLER, Gabi, SHIN, So-Youn, PETERSEN, Ann-Kristin, HYDE, Craig, PSATHA, Maria, WARD, Kirsten J

Volltext

Epigenome-Wide Association Study of Incident Type 2 Diabetes in a British Population: EPIC-Norfolk Study von Cardona, Alexia, Day, Felix R, Perry, John R B, Loh, Marie, Chu, Audrey Y, Lehne, Benjamin, Paul, Dirk S, Lotta, Luca A, Stewart, Isobel D, Kerrison, Nicola D, Scott, Robert A, Khaw, Kay-Tee, Forouhi, Nita G, Langenberg, Claudia, Liu, Chunyu, Mendelson, Michael M, Levy, Daniel, Beck, Stephan, Leslie, R David, Dupuis, Josée, Meigs, James B, Kooner, Jaspal S, Pihlajamäki, Jussi, Vaag, Allan, Perfilyev, Alexander, Ling, Charlotte, Hivert, Marie-France, Chambers, John C, Wareham, Nicholas J, Ong, Ken K

Volltext

Shared genetic aetiology of puberty timing between sexes and with health-related outcomes von Day, Felix R., Bulik-Sullivan, Brendan, Hinds, David A., Finucane, Hilary K., Murabito, Joanne M., Tung, Joyce Y., Ong, Ken K., Perry, John R.B.

Volltext

Genetic evidence for a normal-weight "metabolically obese" phenotype linking insulin resistance, hypertension, coronary artery disease, and type 2 diabetes von Yaghootkar, Hanieh, Scott, Robert A, White, Charles C, Zhang, Weihua, Speliotes, Elizabeth, Munroe, Patricia B, Ehret, Georg B, Bis, Joshua C, Fox, Caroline S, Walker, Mark, Borecki, Ingrid B, Knowles, Joshua W, Yerges-Armstrong, Laura, Ohlsson, Claes, Perry, John R B, Chambers, John C, Kooner, Jaspal S, Franceschini, Nora, Langenberg, Claudia, Hivert, Marie-France, Dastani, Zari, Richards, J Brent, Semple, Robert K, Frayling, Timothy M

Volltext

Correction: Genome-Wide Association Studies of Asthma in Population-Based Cohorts Confirm Known and Suggested Loci and Identify an Additional Association near HLA von Ramasamy, Adaikalavan, Kuokkanen, Mikko, Vedantam, Sailaja, Gajdos, Zofia K, Couto Alves, Alexessander, Lyon, Helen N, Ferreira, Manuel A R, Strachan, David P, Zhao, Jing Hua, Abramson, Michael J, Brown, Matthew A, Coin, Lachlan, Dharmage, Shyamali C, Duffy, David L, Haahtela, Tari, Heath, Andrew C, Janson, Christer, Kähönen, Mika, Khaw, Kay-Tee, Laitinen, Jaana, Le Souef, Peter, Lehtimäki, Terho, Madden, Pamela A F, Marks, Guy B, Martin, Nicholas G, Matheson, Melanie C, Palmer, Cameron D, Palotie, Aarno, Pouta, Anneli, Robertson, Colin F, Viikari, Jorma, Widen, Elisabeth, Wjst, Matthias, Jarvis, Deborah L, Montgomery, Grant W, Thompson, Philip J, Wareham, Nick, Eriksson, Johan, Jousilahti, Pekka, Laitinen, Tarja, Pekkanen, Juha, Raitakari, Olli T, O'Connor, George T, Salomaa, Veikko, Jarvelin, Marjo-Riitta, Hirschhorn, Joel N

Volltext

Population-Based Genome-wide Association Studies Reveal Six Loci Influencing Plasma Levels of Liver Enzymes von Yuan, Xin, Waterworth, Dawn, Perry, John R.B., Lim, Noha, Song, Kijoung, Chambers, John C., Zhang, Weihua, Vollenweider, Peter, Stirnadel, Heide, Johnson, Toby, Bergmann, Sven, Beckmann, Noam D., Li, Yun, Ferrucci, Luigi, Melzer, David, Hernandez, Dena, Singleton, Andrew, Scott, James, Elliott, Paul, Waeber, Gerard, Cardon, Lon, Frayling, Timothy M., Kooner, Jaspal S., Mooser, Vincent

Volltext

Genome-wide association study with 1000 genomes imputation identifies signals for nine sex hormone-related phenotypes von Ruth, Katherine S, Campbell, Purdey J, Chew, Shelby, Lim, Ee Mun, Hadlow, Narelle, Stuckey, Bronwyn G A, Brown, Suzanne J, Feenstra, Bjarke, Joseph, John, Surdulescu, Gabriela L, Zheng, Hou Feng, Richards, J Brent, Murray, Anna, Spector, Tim D, Wilson, Scott G, Perry, John R B

Volltext

Genetic Regulation of Puberty Timing in Humans von Day, Felix R., Perry, John R.B., Ong, Ken K.

Volltext

Common Variant in the FTO Gene Is Associated with Body Mass Index and Predisposes to Childhood and Adult Obesity von Frayling, Timothy M, Timpson, Nicholas J, Weedon, Michael N, Zeggini, Eleftheria, Freathy, Rachel M, Lindgren, Cecilia M, Perry, John R.B, Elliott, Katherine S, Lango, Hana, Rayner, Nigel W, Shields, Beverley, Harries, Lorna W, Barrett, Jeffrey C, Ellard, Sian, Groves, Christopher J, Knight, Bridget, Patch, Ann-Marie, Ness, Andrew R, Ebrahim, Shah, Lawlor, Debbie A, Ring, Susan M, Ben-Shlomo, Yoav, Jarvelin, Marjo-Riitta, Sovio, Ulla, Bennett, Amanda J, Melzer, David, Ferrucci, Luigi, Loos, Ruth J.F, Barroso, Inês, Wareham, Nicholas J, Karpe, Fredrik, Owen, Katharine R, Cardon, Lon R, Walker, Mark, Hitman, Graham A, Palmer, Colin N.A, Doney, Alex S.F, Morris, Andrew D, Smith, George Davey, Hattersley, Andrew T, McCarthy, Mark I

Volltext

Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes von Perry, John R.B., Weedon, Michael N., Langenberg, Claudia, Jackson, Anne U., Lyssenko, Valeriya, Sparsø, Thomas, Thorleifsson, Gudmar, Grallert, Harald, Ferrucci, Luigi, Maggio, Marcello, Paolisso, Giuseppe, Walker, Mark, Palmer, Colin N.A., Payne, Felicity, Young, Elizabeth, Herder, Christian, Narisu, Narisu, Morken, Mario A., Bonnycastle, Lori L., Owen, Katharine R., Shields, Beverley, Knight, Beatrice, Bennett, Amanda, Groves, Christopher J., Ruokonen, Aimo, Jarvelin, Marjo Riitta, Pearson, Ewan, Pascoe, Laura, Ferrannini, Ele, Bornstein, Stefan R., Stringham, Heather M., Scott, Laura J., Kuusisto, Johanna, Nilsson, Peter, Neptin, Malin, Gjesing, Anette P., Pisinger, Charlotta, Lauritzen, Torsten, Sandbaek, Annelli, Sampson, Mike, Zeggini, MAGIC, Ele, Lindgren, Cecilia M., Steinthorsdottir, Valgerdur, Thorsteinsdottir, Unnur, Hansen, Torben, Schwarz, Peter, Illig, Thomas, Laakso, Markku, Stefansson, Kari, Morris, Andrew D., Groop, Leif, Pedersen, Oluf, Boehnke, Michael, Barroso, Inês, Wareham, Nicholas J., Hattersley, Andrew T., McCarthy, Mark I., Frayling, Timothy M.

Volltext