Abstract A053: ErbB3 downregulation enhances luminal breast tumor response to antiestrogens von Morrison, Meghan M., Stanford, Jamie, Young, Christian, Vaught, David, Williams, Andrew, williams, michelle, Perou, Chuck M., Arteaga, Carlos L., Cook, Rebecca S.

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A model of breast cancer heterogeneity reveals vascular mimicry as a driver of metastasis von Wagenblast, Elvin, Soto, Mar, Gutiérrez-Ángel, Sara, Hartl, Christina A., Gable, Annika L., Maceli, Ashley R., Erard, Nicolas, Williams, Alissa M., Kim, Sun Y., Dickopf, Steffen, Harrell, J. Chuck, Smith, Andrew D., Perou, Charles M., Wilkinson, John E., Hannon, Gregory J., Knott, Simon R. V.

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Sox10 Regulates Stem/Progenitor and Mesenchymal Cell States in Mammary Epithelial Cells von Dravis, Christopher, Spike, Benjamin T., Harrell, J. Chuck, Johns, Claire, Trejo, Christy L., Southard-Smith, E. Michelle, Perou, Charles M., Wahl, Geoffrey M.

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Characterization of cell lines derived from breast cancers and normal mammary tissues for the study of the intrinsic molecular subtypes von Prat, Aleix, Karginova, Olga, Parker, Joel S., Fan, Cheng, He, Xiaping, Bixby, Lisa, Harrell, J. Chuck, Roman, Erick, Adamo, Barbara, Troester, Melissa, Perou, Charles M.

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The long-term prognostic and predictive capacity of cyclin D1 gene amplification in 2305 breast tumours von Lundberg, Arian, Lindström, Linda S, Li, Jingmei, Harrell, J Chuck, Darai-Ramqvist, Eva, Sifakis, Emmanouil G, Foukakis, Theodoros, Perou, Charles M, Czene, Kamila, Bergh, Jonas, Tobin, Nicholas P

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Asparagine bioavailability governs metastasis in a model of breast cancer von Knott, Simon R. V., Wagenblast, Elvin, Khan, Showkhin, Kim, Sun Y., Soto, Mar, Wagner, Michel, Turgeon, Marc-Olivier, Fish, Lisa, Erard, Nicolas, Gable, Annika L., Maceli, Ashley R., Dickopf, Steffen, Papachristou, Evangelia K., D’Santos, Clive S., Carey, Lisa A., Wilkinson, John E., Harrell, J. Chuck, Perou, Charles M., Goodarzi, Hani, Poulogiannis, George, Hannon, Gregory J.

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Genomic analysis identifies unique signatures predictive of brain, lung, and liver relapse von Harrell, J. Chuck, Prat, Aleix, Parker, Joel S., Fan, Cheng, He, Xiaping, Carey, Lisa, Anders, Carey, Ewend, Matthew, Perou, Charles M.

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Gene Expression Signatures and Immunohistochemical Subtypes Add Prognostic Value to Each Other in Breast Cancer Cohorts von Lundberg, Arian, Lindström, Linda S, Harrell, J Chuck, Falato, Claudette, Carlson, Joseph W, Wright, Paul K, Foukakis, Theodoros, Perou, Charles M, Czene, Kamila, Bergh, Jonas, Tobin, Nicholas P

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Separation of breast cancer and organ microenvironment transcriptomes in metastases von Alzubi, Mohammad A, Turner, Tia H, Olex, Amy L, Sohal, Sahib S, Tobin, Nicholas P, Recio, Susana G, Bergh, Jonas, Hatschek, Thomas, Parker, Joel S, Sartorius, Carol A, Perou, Charles M, Dozmorov, Mikhail G, Harrell, J Chuck

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Maintenance of hormone responsiveness in luminal breast cancers by suppression of Notch von Haughian, James M, Pinto, Mauricio P, Harrell, J. Chuck, Bliesner, Brian S, Joensuu, Kristiina M, Dye, Wendy W, Sartorius, Carol A, Tan, Aik Choon, Heikkilä, Päivi, Perou, Charles M, Horwitz, Kathryn B

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The Six1 oncoprotein downregulates p53 via concomitant regulation of RPL26 and microRNA-27a-3p von Towers, Christina G., Guarnieri, Anna L., Micalizzi, Doug S., Harrell, J. Chuck, Gillen, Austin E., Kim, Jihye, Wang, Chu-An, Oliphant, Michael U.J., Drasin, David J., Guney, Michelle A., Kabos, Peter, Sartorius, Carol A., Tan, Aik-Choon, Perou, Charles M., Espinosa, Joaquin M., Ford, Heide L.

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Differentiation and loss of malignant character of spontaneous pulmonary metastases in patient-derived breast cancer models von Bockhorn, Jessica, Prat, Aleix, Chang, Ya-Fang, Liu, Xia, Huang, Simo, Shang, Meng, Nwachukwu, Chika, Gomez-Vega, Maria J, Harrell, J Chuck, Olopade, Olufunmilayo I, Perou, Charles M, Liu, Huiping

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Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts von Pfefferle, Adam D, Herschkowitz, Jason I, Usary, Jerry, Chuck Harrell, Joshua, Spike, Benjamin T, Adams, Jessica R, Torres-Arzayus, Maria I, Brown, Myles, Egan, Sean E, Wahl, Geoffrey M, Rosen, Jeffrey M, Perou, Charles M

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CIB1 depletion impairs cell survival and tumor growth in triple-negative breast cancer von Black, Justin L., Harrell, J. Chuck, Leisner, Tina M., Fellmeth, Melissa J., George, Samuel D., Reinhold, Dominik, Baker, Nicole M., Jones, Corbin D., Der, Channing J., Perou, Charles M., Parise, Leslie V.

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Interactions with fibroblasts are distinct in Basal-like and luminal breast cancers von Camp, J Terese, Elloumi, Fathi, Roman-Perez, Erick, Rein, Jessica, Stewart, Delisha A, Harrell, J Chuck, Perou, Charles M, Troester, Melissa A

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Single‐cell transcriptional atlas of human breast cancers and model systems von Altman, Julia E., Olex, Amy L., Zboril, Emily K., Walker, Carson J., Boyd, David C., Myrick, Rachel K., Hairr, Nicole S., Koblinski, Jennifer E., Puchalapalli, Madhavi, Hu, Bin, Dozmorov, Mikhail G., Chen, X. Steven, Chen, Yunshun, Perou, Charles M., Lehmann, Brian D., Visvader, Jane E., Harrell, J. Chuck

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PAM50 Provides Prognostic Information When Applied to the Lymph Node Metastases of Advanced Breast Cancer Patients von Tobin, Nicholas P, Lundberg, Arian, Lindström, Linda S, Harrell, J Chuck, Foukakis, Theodoros, Carlsson, Lena, Einbeigi, Zakaria, Linderholm, Barbro K, Loman, Niklas, Malmberg, Martin, Fernö, Mårten, Czene, Kamila, Perou, Charles M, Bergh, Jonas, Hatschek, Thomas

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Identification of a stable molecular signature in mammary tumor endothelial cells that persists in vitro von Xiao, Lin, Harrell, J. Chuck, Perou, Charles M., Dudley, Andrew C.

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Endothelial-like properties of claudin-low breast cancer cells promote tumor vascular permeability and metastasis von Harrell, J. Chuck, Pfefferle, Adam D., Zalles, Nicole, Prat, Aleix, Fan, Cheng, Khramtsov, Andrey, Olopade, Olufunmilayo I., Troester, Melissa A., Dudley, Andrew C., Perou, Charles M.

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Primary breast tumor-derived cellular models: characterization of tumorigenic, metastatic, and cancer-associated fibroblasts in dissociated tumor (DT) cultures von Drews-Elger, Katherine, Brinkman, Joeli A., Miller, Philip, Shah, Sanket H., Harrell, J. Chuck, da Silva, Thiago G., Ao, Zheng, Schlater, Amy, Azzam, Diana J., Diehl, Kathleen, Thomas, Dafydd, Slingerland, Joyce M., Perou, Charles M., Lippman, Marc E., El-Ashry, Dorraya

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