Enantioselective reductions of 2-acyl-1,3-dithianes using the corey oxazaborolidine catalyst von DeNinno, Michael P., Perner, Richard I., Lijewski, Linda

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The landscape of selection in 551 esophageal adenocarcinomas defines genomic biomarkers for the clinic von Frankell, Alexander M., Jammula, SriGanesh, Li, Xiaodun, Contino, Gianmarco, Killcoyne, Sarah, Abbas, Sujath, Perner, Juliane, Bower, Lawrence, Devonshire, Ginny, Ococks, Emma, Grehan, Nicola, Mok, James, O’Donovan, Maria, MacRae, Shona, Eldridge, Matthew D., Tavaré, Simon, Fitzgerald, Rebecca C.

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TRPA1 Modulation of Spontaneous and Mechanically Evoked Firing of Spinal Neurons in Uninjured, Osteoarthritic, and Inflamed Rats von McGaraughty, Steve, Chu, Katharine L, Perner, Richard J, DiDomenico, Stan, Kort, Michael E, Kym, Philip R

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DOPAMIN-AGONISTEN von DIDOMENICO, STANLEY, JR., GURNEE, IL 60031, US, DEBERNARDIS, JOHN, F., LINDENHURST, IL 60046, US, PERNER, RICHARD, J., GURNEE, IL 60031, US, STOUT, DAVID, M., METTAWA, IL 60048, US, DE, BISWANATH, VERNON HILLS, IL 60061, US, LIJEWSKI, LINDA, M., OAK CREEK, WI 53154, US, MORTON, HOWARD, E., GURNEE, IL 60031, US, SCHOENLEBER, ROBERT, W., DEERFIELD, IL 60015, US, BASHA, FATIMA, Z., LAKE FOREST, IL 60045, US, CAMPBELL, JAMES, R., FT. SHERIDAN, IL 60037, US, MARTIN, YVONNE, C., WAUKEGAN, IL 60087, US, HSIAO, CHI-NUNG, W., LIBERTYVILLE, IL 60048, US, DENINNO, MICHAEL, P., WILDWOOD, IL 60030, US, MEYER, MICHEAL, D., LINDENHURST, IL 60046, US, EHRLICH, PAUL, P., EVANSTON, IL 60201, US, KEBABIAN, JOHN, W., LAKE BLUFF, IL 60044, US

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A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia von Krivtsov, Andrei V., Evans, Kathryn, Gadrey, Jayant Y., Eschle, Benjamin K., Hatton, Charlie, Uckelmann, Hannah J., Ross, Kenneth N., Perner, Florian, Olsen, Sarah N., Pritchard, Tara, McDermott, Lisa, Jones, Connor D., Jing, Duohui, Braytee, Ali, Chacon, Diego, Earley, Eric, McKeever, Brian M., Claremon, David, Gifford, Andrew J., Lee, Heather J., Teicher, Beverly A., Pimanda, John E., Beck, Dominik, Perry, Jennifer A., Smith, Malcolm A., McGeehan, Gerard M., Lock, Richard B., Armstrong, Scott A.

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Selective blockade of TRPA1 channel attenuates pathological pain without altering noxious cold sensation or body temperature regulation von Chen, Jun, Joshi, Shailen K., DiDomenico, Stanley, Perner, Richard J., Mikusa, Joe P., Gauvin, Donna M., Segreti, Jason A., Han, Ping, Zhang, Xu-Feng, Niforatos, Wende, Bianchi, Bruce R., Baker, Scott J., Zhong, Chengmin, Simler, Gricelda H., McDonald, Heath A., Schmidt, Robert G., McGaraughty, Steve P., Chu, Katharine L., Faltynek, Connie R., Kort, Michael E., Reilly, Regina M., Kym, Philip R.

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Identification of Subtypes of Barrett’s Esophagus and Esophageal Adenocarcinoma Based on DNA Methylation Profiles and Integration of Transcriptome and Genome Data von Jammula, SriGanesh, Katz-Summercorn, Annalise C., Li, Xiaodun, Linossi, Constanza, Smyth, Elizabeth, Killcoyne, Sarah, Biasci, Daniele, Subash, Vinod V., Abbas, Sujath, Blasko, Adrienn, Devonshire, Ginny, Grantham, Amber, Wronowski, Filip, O’Donovan, Maria, Grehan, Nicola, Eldridge, Matthew D., Tavaré, Simon, Fitzgerald, Rebecca C., Noorani, Ayesha, Edwards, Paul A.W., Grehan, Nicola, Nutzinger, Barbara, Hughes, Caitriona, Fidziukiewicz, Elwira, Bornschein, Jan, MacRae, Shona, Crawte, Jason, Northrop, Alex, Contino, Gianmarco, Li, Xiaodun, de la Rue, Rachel, O’Donovan, Maria, Miremadi, Ahmad, Malhotra, Shalini, Tripathi, Monika, Tavaré, Simon, Lynch, Andy G., Eldridge, Matthew, Secrier, Maria, Bower, Lawrence, Devonshire, Ginny, Perner, Juliane, Jammula, Sriganesh, Davies, Jim, Crichton, Charles, Carroll, Nick, Safranek, Peter, Hindmarsh, Andrew, Sujendran, Vijayendran, Hayes, Stephen J., Ang, Yeng, Preston, Shaun R., Oakes, Sarah, Bagwan, Izhar, Save, Vicki, Skipworth, Richard J.E., Hupp, Ted R., O’Neill, J. Robert, Tucker, Olga, Beggs, Andrew, Taniere, Philippe, Puig, Sonia, Underwood, Timothy J., Noble, Fergus, Owsley, Jack, Barr, Hugh, Shepherd, Neil, Old, Oliver, Lagergren, Jesper, Gossage, James, Davies, Andrew, Chang, Fuju, Zylstra, Janine, Mahadeva, Ula, Goh, Vicky, Ciccarelli, Francesca D., Sanders, Grant, Berrisford, Richard, Harden, Catherine, Lewis, Mike, Cheong, Ed, Kumar, Bhaskar, Parsons, Simon L., Soomro, Irshad, Kaye, Philip, Saunders, John, Lovat, Laurence, Haidry, Rehan, Igali, Laszlo, Scott, Michael, Sothi, Sharmila, Suortamo, Sari, Lishman, Suzy, Hanna, George B., Moorthy, Krishna, Peters, Christopher J., Grabowska, Anna, Turkington, Richard, Fitzgerald, Rebecca C.

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Patient-specific cancer genes contribute to recurrently perturbed pathways and establish therapeutic vulnerabilities in esophageal adenocarcinoma von Mourikis, Thanos P., Benedetti, Lorena, Foxall, Elizabeth, Temelkovski, Damjan, Nulsen, Joel, Perner, Juliane, Cereda, Matteo, Lagergren, Jesper, Howell, Michael, Yau, Christopher, Fitzgerald, Rebecca C., Scaffidi, Paola, Ciccarelli, Francesca D.

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Transcriptomic profiling reveals three molecular phenotypes of adenocarcinoma at the gastroesophageal junction von Bornschein, Jan, Wernisch, Lorenz, Secrier, Maria, Miremadi, Ahmad, Perner, Juliane, MacRae, Shona, O'Donovan, Maria, Newton, Richard, Menon, Suraj, Bower, Lawrence, Eldridge, Matthew D., Devonshire, Ginny, Cheah, Calvin, Turkington, Richard, Hardwick, Richard H., Selgrad, Michael, Venerito, Marino, Malfertheiner, Peter, Fitzgerald, Rebecca C., Noorani, Ayesha, Elliott, Rachael Fels, Edwards, Paul A.W., Grehan, Nicola, Nutzinger, Barbara, Crawte, Jason, Chettouh, Hamza, Contino, Gianmarco, Li, Xiaodun, Gregson, Eleanor, Zeki, Sebastian, Rue, Rachel, Malhotra, Shalini, Tavaré, Simon, Lynch, Andy G., Smith, Mike L., Davies, Jim, Crichton, Charles, Carroll, Nick, Safranek, Peter, Hindmarsh, Andrew, Sujendran, Vijayendran, Hayes, Stephen J., Ang, Yeng, Preston, Shaun R., Oakes, Sarah, Bagwan, Izhar, Save, Vicki, Skipworth, Richard J.E., Hupp, Ted R., Robert O'Neill, J., Tucker, Olga, Beggs, Andrew, Taniere, Philippe, Puig, Sonia, Underwood, Timothy J., Noble, Fergus, Owsley, Jack, Barr, Hugh, Shepherd, Neil, Old, Oliver, Lagergren, Jesper, Gossage, James, Davies, Andrew, Chang, Fuju, Zylstra, Janine, Goh, Vicky, Ciccarelli, Francesca D., Sanders, Grant, Berrisford, Richard, Harden, Catherine, Bunting, David, Lewis, Mike, Cheong, Ed, Kumar, Bhaskar, Parsons, Simon L., Soomro, Irshad, Kaye, Philip, Saunders, John, Lovat, Laurence, Haidry, Rehan, Eneh, Victor, Igali, Laszlo, Scott, Michael, Sothi, Shamila, Suortamo, Sari, Lishman, Suzy, Hanna, George B., Peters, Christopher J., Grabowska, Anna

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Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021 von Evans, Laura, Rhodes, Andrew, Alhazzani, Waleed, Antonelli, Massimo, Coopersmith, Craig M., French, Craig, Machado, Flávia R., Mcintyre, Lauralyn, Ostermann, Marlies, Prescott, Hallie C., Schorr, Christa, Simpson, Steven, Wiersinga, W. Joost, Alshamsi, Fayez, Angus, Derek C., Arabi, Yaseen, Azevedo, Luciano, Beale, Richard, Beilman, Gregory, Belley-Cote, Emilie, Burry, Lisa, Cecconi, Maurizio, Centofanti, John, Coz Yataco, Angel, De Waele, Jan, Dellinger, R. Phillip, Doi, Kent, Du, Bin, Estenssoro, Elisa, Ferrer, Ricard, Gomersall, Charles, Hodgson, Carol, Møller, Morten Hylander, Iwashyna, Theodore, Jacob, Shevin, Kleinpell, Ruth, Klompas, Michael, Koh, Younsuck, Kumar, Anand, Kwizera, Arthur, Lobo, Suzana, Masur, Henry, McGloughlin, Steven, Mehta, Sangeeta, Mehta, Yatin, Mer, Mervyn, Nunnally, Mark, Oczkowski, Simon, Osborn, Tiffany, Papathanassoglou, Elizabeth, Perner, Anders, Puskarich, Michael, Roberts, Jason, Schweickert, William, Seckel, Maureen, Sevransky, Jonathan, Sprung, Charles L., Welte, Tobias, Zimmerman, Janice, Levy, Mitchell

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Identification of Prognostic Phenotypes of Esophageal Adenocarcinoma in 2 Independent Cohorts von Sawas, Tarek, Killcoyne, Sarah, Iyer, Prasad G., Wang, Kenneth K., Smyrk, Thomas C., Kisiel, John B., Qin, Yi, Ahlquist, David A., Rustgi, Anil K., Costa, Rui J., Gerstung, Moritz, Fitzgerald, Rebecca C., Katzka, David A., Noorani, Ayesha, Edwards, Paul A.W., Grehan, Nicola, Nutzinger, Barbara, Hughes, Caitriona, Fidziukiewicz, Elwira, Bornschein, Jan, MacRae, Shona, Crawte, Jason, Contino, Gianmarco, Li, Xiaodun, Rue, Rachel de la, O’Donovan, Maria, Miremad, Ahmad, Malhotra, Shalini, Tripathi, Monika, Tavaré, Simon, Lynch, Andy G., Eldridge, Matthew, Secrier, Maria, Bower, Lawrence, Devonshire, Ginny, Perner, Juliane, Jammula, Sriganesh, Davies, Jim, Crichton, Charles, Carroll, Nick, Safranek, Peter, Hindmarsh, Andrew, Sujendran, Vijayendran, Hayes, Stephen J., Ang, Yeng, Preston, Shaun R., Oakes, Sarah, Bagwan, Izhar, Save, Vicki, Skipworth, Richard J.E., Hupp, Ted R., O’Neill, J. Robert, Tucker, Olga, Beggs, Andrew, Taniere, Philippe, Puig, Sonia, Underwood, Timothy J., Noble, Fergus, Owsley, Jack, Barr, Hugh, Shepherd, Neil, Old, Oliver, Lagergren, Jesper, Gossage, James, Davies, Andrew, Chang, Fuju, Zylstra, Janine, Mahadeva, Ula, Goh, Vicky, Ciccarelli, Francesca D., Sanders, Grant, Berrisford, Richard, Harden, Catherine, Bunting, David, Lewis, Mike, Cheong, Ed, Kumar, Bhaskar, Parsons, Simon L., Soomro, Irshad, Kaye, Philip, Saunders, John, Lovat, Laurence, Haidry, Rehan, Eneh, Victor, Igali, Laszlo, Scott, Michael, Sothi, Sharmila, Suortamo, Sari, Lishman, Suzy, Hanna, George B., Peters, Christopher J., Grabowska, Anna, Turkington, Richard

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Immune activation by DNA damage predicts response to chemotherapy and survival in oesophageal adenocarcinoma von Turkington, Richard C, Knight, Laura A, Blayney, Jaine K, Secrier, Maria, Douglas, Rosalie, Parkes, Eileen E, Sutton, Eilis K, Stevenson, Leanne, McManus, Damian, Halliday, Sophia, McCavigan, Andrena M, Logan, Gemma E, Walker, Steven M, Steele, Christopher J, Perner, Juliane, Bornschein, Jan, MacRae, Shona, Miremadi, Ahmad, McCarron, Eamon, McQuaid, Stephen, Arthur, Kenneth, James, Jacqueline A, Eatock, Martin M, O’Neill, Robert, Noble, Fergus, Underwood, Timothy J, Harkin, D Paul, Salto-Tellez, Manuel, Fitzgerald, Rebecca C, Kennedy, Richard D

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Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021 von Evans, Laura, Rhodes, Andrew, Alhazzani, Waleed, Antonelli, Massimo, Coopersmith, Craig M., French, Craig, Machado, Flavia R., Mcintyre, Lauralyn, Ostermann, Marlies, Prescott, Hallie C., Schorr, Christa, Simpson, Steven, Wiersinga, W. Joost, Alshamsi, Fayez, Angus, Derek C., Arabi, Yaseen, Azevedo, Luciano, Beale, Richard, Beilman, Gregory, Belley-Cote, Emilie, Burry, Lisa, Cecconi, Maurizio, Centofanti, John, Coz Yataco, Angel, De Waele, Jan, Dellinger, R. Phillip, Doi, Kent, Du, Bin, Estenssoro, Elisa, Ferrer, Ricard, Gomersall, Charles, Hodgson, Carol, Moller, Morten Hylander, Iwashyna, Theodore, Jacob, Shevin, Kleinpell, Ruth, Klompas, Michael, Koh, Younsuck, Kumar, Anand, Kwizera, Arthur, Lobo, Suzana, Masur, Henry, McGloughlin, Steven, Mehta, Sangeeta, Mehta, Yatin, Mer, Mervyn, Nunnally, Mark, Oczkowski, Simon, Osborn, Tiffany, Papathanassoglou, Elizabeth, Perner, Anders, Puskarich, Michael, Roberts, Jason, Schweickert, William, Seckel, Maureen, Sevransky, Jonathan, Sprung, Charles L., Welte, Tobias, Zimmerman, Janice, Levy, Mitchell

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The menin inhibitor revumenib in KMT2A-rearranged or NPM1-mutant leukaemia von Issa, Ghayas C., Aldoss, Ibrahim, DiPersio, John, Cuglievan, Branko, Stone, Richard, Arellano, Martha, Thirman, Michael J., Patel, Manish R., Dickens, David S., Shenoy, Shalini, Shukla, Neerav, Kantarjian, Hagop, Armstrong, Scott A., Perner, Florian, Perry, Jennifer A., Rosen, Galit, Bagley, Rebecca G., Meyers, Michael L., Ordentlich, Peter, Gu, Yu, Kumar, Vinit, Smith, Steven, McGeehan, Gerard M., Stein, Eytan M.

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Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016 von Rhodes, Andrew, Evans, Laura E., Alhazzani, Waleed, Levy, Mitchell M., Antonelli, Massimo, Ferrer, Ricard, Kumar, Anand, Sevransky, Jonathan E., Sprung, Charles L., Nunnally, Mark E., Rochwerg, Bram, Rubenfeld, Gordon D., Angus, Derek C., Annane, Djillali, Beale, Richard J., Bellinghan, Geoffrey J., Bernard, Gordon R., Chiche, Jean-Daniel, Coopersmith, Craig, De Backer, Daniel P., French, Craig J., Fujishima, Seitaro, Gerlach, Herwig, Hidalgo, Jorge Luis, Hollenberg, Steven M., Jones, Alan E., Karnad, Dilip R., Kleinpell, Ruth M., Koh, Younsuck, Lisboa, Thiago Costa, Machado, Flavia R., Marini, John J., Marshall, John C., Mazuski, John E., McIntyre, Lauralyn A., McLean, Anthony S., Mehta, Sangeeta, Moreno, Rui P., Myburgh, John, Navalesi, Paolo, Nishida, Osamu, Osborn, Tiffany M., Perner, Anders, Plunkett, Colleen M., Ranieri, Marco, Schorr, Christa A., Seckel, Maureen A., Seymour, Christopher W., Shieh, Lisa, Shukri, Khalid A., Simpson, Steven Q., Singer, Mervyn, Thompson, B. Taylor, Townsend, Sean R., Van der Poll, Thomas, Vincent, Jean-Louis, Wiersinga, W. Joost, Zimmerman, Janice L., Dellinger, R. Phillip

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Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016 von Rhodes, Andrew, Evans, Laura E., Alhazzani, Waleed, Levy, Mitchell M., Antonelli, Massimo, Ferrer, Ricard, Kumar, Anand, Sevransky, Jonathan E., Sprung, Charles L., Nunnally, Mark E., Rochwerg, Bram, Rubenfeld, Gordon D., Angus, Derek C., Annane, Djillali, Beale, Richard J., Bellinghan, Geoffrey J., Bernard, Gordon R., Chiche, Jean-Daniel, Coopersmith, Craig, De Backer, Daniel P., French, Craig J., Fujishima, Seitaro, Gerlach, Herwig, Hidalgo, Jorge Luis, Hollenberg, Steven M., Jones, Alan E., Karnad, Dilip R., Kleinpell, Ruth M., Koh, Younsuk, Lisboa, Thiago Costa, Machado, Flavia R., Marini, John J., Marshall, John C., Mazuski, John E., McIntyre, Lauralyn A., McLean, Anthony S., Mehta, Sangeeta, Moreno, Rui P., Myburgh, John, Navalesi, Paolo, Nishida, Osamu, Osborn, Tiffany M., Perner, Anders, Plunkett, Colleen M., Ranieri, Marco, Schorr, Christa A., Seckel, Maureen A., Seymour, Christopher W., Shieh, Lisa, Shukri, Khalid A., Simpson, Steven Q., Singer, Mervyn, Thompson, B. Taylor, Townsend, Sean R., Van der Poll, Thomas, Vincent, Jean-Louis, Wiersinga, W. Joost, Zimmerman, Janice L., Dellinger, R. Phillip

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Effect of a Buffered Crystalloid Solution vs Saline on Acute Kidney Injury Among Patients in the Intensive Care Unit: The SPLIT Randomized Clinical Trial von Young, Paul, Bailey, Michael, Beasley, Richard, Henderson, Seton, Mackle, Diane, McArthur, Colin, McGuinness, Shay, Mehrtens, Jan, Myburgh, John, Psirides, Alex, Reddy, Sumeet, Bellomo, Rinaldo

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Heat export from the tropics drives mid to late Holocene palaeoceanographic changes offshore southern Australia von Perner, Kerstin, Moros, Matthias, De Deckker, Patrick, Blanz, Thomas, Wacker, Lukas, Telford, Richard, Siegel, Herbert, Schneider, Ralph, Jansen, Eystein

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Prostate-specific membrane antigen expression as a predictor of prostate cancer progression von Perner, Sven, MD, Hofer, Matthias D., MD, Kim, Robert, Shah, Rajal B., MD, Li, Haojie, MD, PhD, Möller, Peter, MD, Hautmann, Richard E., MD, Gschwend, Juergen E., MD, Kuefer, Rainer, MD, Rubin, Mark A., MD

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MEN1 mutations mediate clinical resistance to menin inhibition von Perner, Florian, Stein, Eytan M., Wenge, Daniela V., Singh, Sukrit, Kim, Jeonghyeon, Apazidis, Athina, Rahnamoun, Homa, Anand, Disha, Marinaccio, Christian, Hatton, Charlie, Wen, Yanhe, Stone, Richard M., Schaller, David, Mowla, Shoron, Xiao, Wenbin, Gamlen, Holly A., Stonestrom, Aaron J., Persaud, Sonali, Ener, Elizabeth, Cutler, Jevon A., Doench, John G., McGeehan, Gerard M., Volkamer, Andrea, Chodera, John D., Nowak, Radosław P., Fischer, Eric S., Levine, Ross L., Armstrong, Scott A., Cai, Sheng F.

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