The impact of systems approaches on biological problems in drug discovery von Hood, Leroy, Perlmutter, Roger M

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Selective requirement for MAP kinase activation in thymocyte differentiation von Alberola-lla, Jose, Forbush, Katherine A, Seger, Rony, Krebs, Edwin G, Perlmutter, Roger M

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Presenilin-Dependent γ-Secretase Activity Modulates Thymocyte Development von Doerfler, Petra, Shearman, Mark S., Perlmutter, Roger M.

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Activation of the Raf-1 kinase cascade by coumermycin-induced dimerization von Farrar, Michael A, Alberola-lla, José, Perlmutter, Roger M

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A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice von Fero, M L, Rivkin, M, Tasch, M, Porter, P, Carow, C E, Firpo, E, Polyak, K, Tsai, L H, Broudy, V, Perlmutter, R M, Kaushansky, K, Roberts, J M

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T Cell Antigen Receptor-Mediated Activation of the Ras/Mitogen-Activated Protein Kinase Pathway Controls Interleukin 4 Receptor Function and Type-2 Helper T Cell Differentiation von Yamashita, Masakatsu, Kimura, Motoko, Kubo, Masato, Shimizu, Chiori, Tada, Tomio, Perlmutter, Roger M., Nakayama, Toshinori

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Hematopoietic Progenitor Kinase 1 Associates Physically and Functionally with the Adaptor Proteins B Cell Linker Protein and SLP-76 in Lymphocytes von Sauer, K, Liou, J, Singh, S B, Yablonski, D, Weiss, A, Perlmutter, R M

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DIFFERENTIAL SIGNALING BY LYMPHOCYTE ANTIGEN RECEPTORS von Alberola-Ila, Jose, Takaki, Satoshi, Kerner, James D, Perlmutter, Roger M

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Extensions of Lie–Rinehart algebras and cotangent bundle reduction von Huebschmann, J., Perlmutter, M., Ratiu, T. S.

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Control of B Cell Production by the Adaptor Protein Lnk: Definition of a Conserved Family of Signal-Modulating Proteins von Takaki, Satoshi, Sauer, Karsten, Iritani, Brian M, Chien, Sylvia, Ebihara, Yasuhiro, Tsuji, Koh-ichiro, Takatsu, Kiyoshi, Perlmutter, Roger M

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Evidence for selection of a population of multi-reactive B cells into the splenic marginal zone von Chen, X, Martin, F, Forbush, K A, Perlmutter, R M, Kearney, J F

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A mechanism misregulating p27 in tumors discovered in a functional genomic screen von Garrett-Engele, Carrie M, Tasch, Michael A, Hwang, Harry C, Fero, Matthew L, Perlmutter, Roger M, Clurman, Bruce E, Roberts, James M

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Fyn Can Partially Substitute for Lck in T Lymphocyte Development von Groves, Tim, Smiley, Patricia, Cooke, Michael P, Forbush, Katherine, Perlmutter, Roger M, Guidos, Cynthia J

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Impaired Lymphopoiesis and Altered B Cell Subpopulations in Mice Overexpressing Lnk Adaptor Protein von Takaki, Satoshi, Tezuka, Yoshinari, Sauer, Karsten, Kubo, Chiyomi, Kwon, Sang-Mo, Armstead, Erin, Nakao, Kazuki, Katsuki, Motoya, Perlmutter, Roger M, Takatsu, Kiyoshi

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Caspase Enzyme Activity Is Not Essential for Apoptosis During Thymocyte Development von Doerfler, Petra, Forbush, Katherine A, Perlmutter, Roger M

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Three distinct IL-2 signaling pathways mediated by bcl-2, c- myc, and lck cooperate in hematopoietic cell proliferation von Miyazaki, Tadaaki, Liu, Zhao-Jun, Kawahara, Atsuo, Minami, Yasuhiro, Yamada, Kyoko, Tsujimoto, Yoshihide, Barsoumian, Edward L, Perlmutter, Roger M, Taniguchi, Tadatsugu

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Thymic stromal lymphopoietin: a cytokine that promotes the development of IgM+ B cells in vitro and signals via a novel mechanism von Levin, S D, Koelling, R M, Friend, S L, Isaksen, D E, Ziegler, S F, Perlmutter, R M, Farr, A G

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Distinct Signals Mediate Maturation and Allelic Exclusion in Lymphocyte Progenitors von Iritani, Brian M, Alberola-Ila, Jose, Forbush, Katherine A, Perlmutter, Roger M

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209 Ketamine as a Rescue Drug for Patients Presenting With Benzodiazepine-Resistant Status Epilepticus von Pepe, P., Scheppke, K., Garay, S., Crowe, R., Coyle, C., Antevy, P., Zitek, A.(T.), Perlmutter, M., Scheppke, E., Farcy, D.

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Interaction of the unique N-terminal region of tyrosine kinase p56lck with cytoplasmic domains of CD4 and CD8 is mediated by cysteine motifs von TURNER, J. M, BRODSKY, M. H, IRVING, B. A, LEVIN, S. D, PERLMUTTER, R. M, LITTMAN, R. R

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