Activation of GCN2 by the ribosomal P-stalk von Inglis, Alison J., Masson, Glenn R., Shao, Sichen, Perisic, Olga, McLaughlin, Stephen H., Hegde, Ramanujan S., Williams, Roger L.

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Structural basis for VPS34 kinase activation by Rab1 and Rab5 on membranes von Tremel, Shirley, Ohashi, Yohei, Morado, Dustin R., Bertram, Jessie, Perisic, Olga, Brandt, Laura T. L., von Wrisberg, Marie-Kristin, Chen, Zhuo A., Maslen, Sarah L., Kovtun, Oleksiy, Skehel, Mark, Rappsilber, Juri, Lang, Kathrin, Munro, Sean, Briggs, John A. G., Williams, Roger L.

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Oncogenic mutations mimic and enhance dynamic events in the natural activation of phosphoinositide 3-kinase p110α (PIK3CA) von Burke, John E, Perisic, Olga, Masson, Glenn R, Vadas, Oscar, Williams, Roger L

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Paradoxical dominant negative activity of an immunodeficiency-associated activating PIK3R1 variant von Tomlinson, Patsy R, Knox, Rachel G, Perisic, Olga, Su, Helen, Brierley, Gemma V, Williams, Roger L, Semple, Robert K

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Bipartite binding and partial inhibition links DEPTOR and mTOR in a mutually antagonistic embrace von Heimhalt, Maren, Berndt, Alex, Wagstaff, Jane, Anandapadamanaban, Madhanagopal, Perisic, Olga, Maslen, Sarah, McLaughlin, Stephen, Yu, Conny Wing-Heng, Masson, Glenn R, Boland, Andreas, Ni, Xiaodan, Yamashita, Keitaro, Murshudov, Garib N, Skehel, Mark, Freund, Stefan M, Williams, Roger L

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Mechanism of Two Classes of Cancer Mutations in the Phosphoinositide 3-Kinase Catalytic Subunit von Miled, Nabil, Yan, Ying, Hon, Wai-Ching, Perisic, Olga, Zvelebil, Marketa, Inbar, Yuval, Schneidman-Duhovny, Dina, Wolfson, Haim J., Backer, Jonathan M., Williams, Roger L.

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Molecular determinants of PI3Kγ-mediated activation downstream of G-protein–coupled receptors (GPCRs) von Vadas, Oscar, Dbouk, Hashem A., Shymanets, Aliaksei, Perisic, Olga, Burke, John E., Saab, Widian F. Abi, Khalil, Bassem D., Harteneck, Christian, Bresnick, Anne R., Nürnberg, Bernd, Backer, Jonathan M., Williams, Roger L.

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Structural basis for selective recognition of ESCRT-III by the AAA ATPase Vps4 von OBITA, Takayuki, SAKSENA, Suraj, GHAZI-TABATABAI, Sara, GRILL, David J, PERISIC, Olga, EMR, Scott D, WILLIAMS, Roger L

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Characterization of Atg38 and NRBF2, a fifth subunit of the autophagic Vps34/PIK3C3 complex von Ohashi, Yohei, Soler, Nicolas, García Ortegón, Miguel, Zhang, Lufei, Kirsten, Marie L., Perisic, Olga, Masson, Glenn R., Burke, John E., Jakobi, Arjen J., Apostolakis, Apostolos A., Johnson, Christopher M., Ohashi, Maki, Ktistakis, Nicholas T., Sachse, Carsten, Williams, Roger L.

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Structural Determinants of Phosphoinositide 3-Kinase Inhibition by Wortmannin, LY294002, Quercetin, Myricetin, and Staurosporine von Walker, Edward H., Pacold, Michael E., Perisic, Olga, Stephens, Len, Hawkins, Philip T., Wymann, Matthias P., Williams, Roger L.

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ESCRT-I Core and ESCRT-II GLUE Domain Structures Reveal Role for GLUE in Linking to ESCRT-I and Membranes von Teo, Hsiangling, Gill, David J., Sun, Ji, Perisic, Olga, Veprintsev, Dmitry B., Vallis, Yvonne, Emr, Scott D., Williams, Roger L.

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Finding a fitting shoe for Cinderella: Searching for an autophagy inhibitor von Miller, Simon, Oleksy, Arkadiusz, Perisic, Olga, Williams, Roger L.

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ESCRT-III binding protein MITD1 is involved in cytokinesis and has an unanticipated PLD fold that binds membranes von Hadders, Michael A, Agromayor, Monica, Obita, Takayuki, Perisic, Olga, Caballe, Anna, Kloc, Magdalena, Lamers, Meindert H, Williams, Roger L, Martin-Serrano, Juan

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Structural Basis for Arl1-Dependent Targeting of Homodimeric GRIP Domains to the Golgi Apparatus von Panic, Bojana, Perisic, Olga, Veprintsev, Dmitry B, Williams, Roger L, Munro, Sean

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Crystal Structure of a Calcium-Phospholipid Binding Domain from Cytosolic Phospholipase A2 von Perisic, Olga, Fong, Sun, Lynch, Denise E., Bycroft, Mark, Williams, Roger L.

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Architecture of human Rag GTPase heterodimers and their complex with mTORC1 von Anandapadamanaban, Madhanagopal, Masson, Glenn R., Perisic, Olga, Berndt, Alex, Kaufman, Jonathan, Johnson, Chris M., Santhanam, Balaji, Rogala, Kacper B., Sabatini, David M., Williams, Roger L.

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Calcium-dependent Membrane Penetration Is a Hallmark of the C2 Domain of Cytosolic Phospholipase A2 Whereas the C2A Domain of Synaptotagmin Binds Membranes Electrostatically von Davletov, B, Perisic, O, Williams, R L

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Mapping the Phospholipid-binding Surface and Translocation Determinants of the C2 Domain from Cytosolic Phospholipase A2 von Perisic, Olga, Paterson, Hugh F., Mosedale, Georgina, Lara-González, Samuel, Williams, Roger L.

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Paradoxical dominant negative activity of an immunodeficiency-associated activating PIK3R1 variant von Tomlinson, Patsy R, Knox, Rachel G, Perisic, Olga, Su, Helen, Brierley, Gemma V, Williams, Roger L, Semple, Robert K

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Structures of PI4KIIIβ complexes show simultaneous recruitment of Rab11 and its effectors von Burke, John E., Inglis, Alison J., Perisic, Olga, Masson, Glenn R., McLaughlin, Stephen H., Rutaganira, Florentine, Shokat, Kevan M., Williams, Roger L.

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