Direct Chemical Synthesis of Chiral Methanol of 98% ee and Its Conversion to [2H1,3H]Methyl Tosylate and [2H1,3H-Methyl]Methionine von Peric Simov, Biljana, Wuggenig, Frank, Mereiter, Kurt, Andres, Hendrik, France, Julien, Schnelli, Peter, Hammerschmidt, Friedrich

Volltext

Start Selective and Rigidify: The Discovery Path toward a Next Generation of EGFR Tyrosine Kinase Inhibitors von Engelhardt, Harald, Böse, Dietrich, Petronczki, Mark, Scharn, Dirk, Bader, Gerd, Baum, Anke, Bergner, Andreas, Chong, Eugene, Döbel, Sandra, Egger, Georg, Engelhardt, Christian, Ettmayer, Peter, Fuchs, Julian E, Gerstberger, Thomas, Gonnella, Nina, Grimm, Andreas, Grondal, Elisabeth, Haddad, Nizar, Hopfgartner, Barbara, Kousek, Roland, Krawiec, Mariusz, Kriz, Monika, Lamarre, Lyne, Leung, Joyce, Mayer, Moriz, Patel, Nitinchandra D, Simov, Biljana Peric, Reeves, Jonathan T, Schnitzer, Renate, Schrenk, Andreas, Sharps, Bernadette, Solca, Flavio, Stadtmüller, Heinz, Tan, Zhulin, Wunberg, Tobias, Zoephel, Andreas, McConnell, Darryl B

Volltext

Intracellular Trapping of the Selective Phosphoglycerate Dehydrogenase (PHGDH) Inhibitor BI-4924 Disrupts Serine Biosynthesis von Weinstabl, Harald, Treu, Matthias, Rinnenthal, Joerg, Zahn, Stephan K, Ettmayer, Peter, Bader, Gerd, Dahmann, Georg, Kessler, Dirk, Rumpel, Klaus, Mischerikow, Nikolai, Savarese, Fabio, Gerstberger, Thomas, Mayer, Moriz, Zoephel, Andreas, Schnitzer, Renate, Sommergruber, Wolfgang, Martinelli, Paola, Arnhof, Heribert, Peric-Simov, Biljana, Hofbauer, Karin S, Garavel, Géraldine, Scherbantin, Yvonne, Mitzner, Sophie, Fett, Thomas N, Scholz, Guido, Bruchhaus, Jens, Burkard, Michelle, Kousek, Roland, Ciftci, Tuncay, Sharps, Bernadette, Schrenk, Andreas, Harrer, Christoph, Haering, Daniela, Wolkerstorfer, Bernhard, Zhang, Xuechun, Lv, Xiaobing, Du, Alicia, Li, Dongyang, Li, Yali, Quant, Jens, Pearson, Mark, McConnell, Darryl B

Volltext

Chemoenzymatic Synthesis of Stannylated Metomidate as a Precursor for Electrophilic Radiohalogenations ? Regioselective Alkylation of Methyl 1H-Imidazole-5-carboxylate [1] von Hammerschmidt, Friedrich, Peric Simov, Biljana, Schmidt, Susanne, Schneider, Sabine, Zolle, Ilse

Volltext

New Selective Inhibitors of Steroid 11β-Hydroxylation in the Adrenal Cortex. Synthesis and Structure–Activity Relationship of Potent Etomidate Analogues von Zolle, Ilse M, Berger, Michael L, Hammerschmidt, Friedrich, Hahner, Stefanie, Schirbel, Andreas, Peric-Simov, Biljana

Volltext

Discovery of potent and selective HER2 inhibitors with efficacy against HER2 exon 20 insertion-driven tumors, which preserve wild-type EGFR signaling von Wilding, Birgit, Scharn, Dirk, Böse, Dietrich, Baum, Anke, Santoro, Valeria, Chetta, Paolo, Schnitzer, Renate, Botesteanu, Dana A., Reiser, Christoph, Kornigg, Stefan, Knesl, Petr, Hörmann, Alexandra, Köferle, Anna, Corcokovic, Maja, Lieb, Simone, Scholz, Guido, Bruchhaus, Jens, Spina, Markus, Balla, Josef, Peric-Simov, Biljana, Zimmer, Jasmin, Mitzner, Sophie, Fett, Thomas N., Beran, Alexandra, Lamarre, Lyne, Gerstberger, Thomas, Gerlach, Daniel, Bauer, Markus, Bergner, Andreas, Schlattl, Andreas, Bader, Gerd, Treu, Matthias, Engelhardt, Harald, Zahn, Stephan, Fuchs, Julian E., Zuber, Johannes, Ettmayer, Peter, Pearson, Mark, Petronczki, Mark, Kraut, Norbert, McConnell, Darryl B., Solca, Flavio, Neumüller, Ralph A.

Volltext

New selective inhibitors of steroid 11beta-hydroxylation in the adrenal cortex. Synthesis and structure-activity relationship of potent etomidate analogues von Zolle, Ilse M, Berger, Michael L, Hammerschmidt, Friedrich, Hahner, Stefanie, Schirbel, Andreas, Peric-Simov, Biljana

Volltext

New Selective Inhibitors of Steroid 11β-Hydroxylation in the Adrenal Cortex. Synthesis and Structure−Activity Relationship of Potent Etomidate Analogues von Zolle, Ilse M, Berger, Michael L, Hammerschmidt, Friedrich, Hahner, Stefanie, Schirbel, Andreas, Peric-Simov, Biljana

Volltext

Indirect Evidence for the Biosynthesis of (1S,2S)-1,2-Epoxypropylphosphonic Acid as a Co-Metabolite of Fosfomycin [(1R,2S)-1,2-Epoxypropylphosphonic Acid] by Streptomyces fradiae von Peric Simov, Biljana, Wuggenig, Frank, Lämmerhofer, Michael, Lindner, Wolfgang, Zarbl, Elfriede, Hammerschmidt, Friedrich

Volltext

Chiral Carbanions, Part 4: Borylation of (Trimethylsilyl)methyl N,N-Dialkylcarbamates - Diastereoselectivity and Structural Studies von Simov, Biljana Peric, Rohn, Agnieszka, Brecker, Lothar, Giester, Gerald, Hammerschmidt, Friedrich

Volltext

Simultaneous separation of the stereoisomers of 1-amino-2-hydroxy and 2-amino-1-hydroxypropane phosphonic acids by stereoselective capillary electrophoresis employing a quinine car... von Lämmerhofer, Michael, Zarbl, Elfriede, Lindner, Wolfgang, Simov, Biljana Peric, Hammerschmidt, Friedrich

Volltext

Configurational Stability and Stannylation of Dipole-Stabilised Cyclic Tertiary Benzylic α-Oxycarbanions, which Occurs with Retention or Inversion of Configuration Depending on R a... von Hammerschmidt, Friedrich, Hanninger, Achim, Simov, Biljana Peric, Völlenkle, Horst, Werner, Andreas

Volltext

Chemoenzymatic Synthesis of Stannylated Metomidate as a Precursor for Electrophilic Radiohalogenations - Regioselective Alkylation of Methyl 1H-Imidazole-5-carboxylate von Hammerschmidt, Friedrich, Simov, Biljana Peric, Schmidt, Susanne, Schneider, Sabine, Zolle, Ilse

Volltext