Hepatocyte organoids and cell transplantation: What the future holds von Peng, Weng Chuan, Kraaier, Lianne J., Kluiver, Thomas A.

Volltext

The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength von de Lau, Wim, Peng, Weng Chuan, Gros, Piet, Clevers, Hans

Volltext

Structure of Stem Cell Growth Factor R-spondin 1 in Complex with the Ectodomain of Its Receptor LGR5 von Peng, Weng Chuan, de Lau, Wim, Forneris, Federico, Granneman, Joke C.M., Huch, Meritxell, Clevers, Hans, Gros, Piet

Volltext

Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo von Miao, Yi, Ha, Andrew, de Lau, Wim, Yuki, Kanako, Santos, António J.M., You, Changjiang, Geurts, Maarten H., Puschhof, Jens, Pleguezuelos-Manzano, Cayetano, Peng, Weng Chuan, Senlice, Ramazan, Piani, Carol, Buikema, Jan W., Gbenedio, Oghenekevwe M., Vallon, Mario, Yuan, Jenny, de Haan, Sanne, Hemrika, Wieger, Rösch, Kathrin, Dang, Luke T., Baker, David, Ott, Melanie, Depeille, Philippe, Wu, Sean M., Drost, Jarno, Nusse, Roeland, Roose, Jeroen P., Piehler, Jacob, Boj, Sylvia F., Janda, Claudia Y., Clevers, Hans, Kuo, Calvin J., Garcia, K. Christopher

Volltext

Structures of Wnt-antagonist ZNRF3 and its complex with R-spondin 1 and implications for signaling von Peng, Weng Chuan, de Lau, Wim, Madoori, Pramod K, Forneris, Federico, Granneman, Joke C M, Clevers, Hans, Gros, Piet

Volltext

Divergent WNT signaling and drug sensitivity profiles within hepatoblastoma tumors and organoids von Kluiver, Thomas A., Lu, Yuyan, Schubert, Stephanie A., Kraaier, Lianne J., Ringnalda, Femke, Lijnzaad, Philip, DeMartino, Jeff, Megchelenbrink, Wouter L., Amo-Addae, Vicky, Eising, Selma, de Faria, Flavia W., Münter, Daniel, van de Wetering, Marc, Kerl, Kornelius, Duiker, Evelien, van den Heuvel, Marius C., de Meijer, Vincent E., de Kleine, Ruben H., Molenaar, Jan J., Margaritis, Thanasis, Stunnenberg, Hendrik G., de Krijger, Ronald R., Zsiros, József, Clevers, Hans, Peng, Weng Chuan

Volltext

Systematic discovery of gene fusions in pediatric cancer by integrating RNA-seq and WGS von van Belzen, Ianthe A E M, Cai, Casey, van Tuil, Marc, Badloe, Shashi, Strengman, Eric, Janse, Alex, Verwiel, Eugène T P, van der Leest, Douwe F M, Kester, Lennart, Molenaar, Jan J, Meijerink, Jules, Drost, Jarno, Peng, Weng Chuan, Kerstens, Hindrik H D, Tops, Bastiaan B J, Holstege, Frank C P, Kemmeren, Patrick, Hehir-Kwa, Jayne Y

Volltext

Extracellular vesicle‐mediated delivery of CRISPR/Cas9 ribonucleoprotein complex targeting proprotein convertase subtilisin‐kexin type 9 (Pcsk9) in primary mouse hepatocytes von Ilahibaks, Nazma F., Kluiver, Thomas A., Jong, Olivier G., Jager, Saskia C. A., Schiffelers, Raymond M., Vader, Pieter, Peng, Weng Chuan, Lei, Zhiyong, Sluijter, Joost P. G.

Volltext

Targeting pediatric cancers via T-cell recognition of the monomorphic MHC class I-related protein MR1 von Cornel, Annelisa M., van der Sman, Loutje, van Dinter, Jip T, Arrabito, Marta, Dunnebach, Ester, van Hoesel, Marliek, Kluiver, Thomas A, Lopes, Ana P, Dautzenberg, Noël M M, Dekker, Linde, van Rijn, Jorik M, van den Beemt, Denise A M H, Buhl, Juliane L, du Chatinier, Aimee, Barneh, Farnaz, Lu, Yuyan, Lo Nigro, Luca, Krippner-Heidenreich, Anja, Sebestyén, Zsolt, Kuball, Jurgen, Hulleman, Esther, Drost, Jarno, van Heesch, Sebastiaan, Heidenreich, Olaf T, Peng, Weng Chuan, Nierkens, Stefan

Volltext

FRI-480 Multi-dimensional profiling of hepatoblastomas and patientderived tumor organoids uncovers tumor subpopulations with divergent WNT activation profiles and drug sensitivitie... von Peng, Weng Chuan

Volltext

A single-cell transcriptomic atlas characterizes ageing tissues in the mouse von Almanzar, Nicole, Antony, Jane, Baghel, Ankit S, Bakerman, Isaac, Bansal, Ishita, Barres, Ben A, Beachy, Philip A

Volltext

Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris von Schaum, Nicholas, Karkanias, Jim, Neff, Norma F., May, Andrew P., Quake, Stephen R., Wyss-Coray, Tony, Darmanis, Spyros, Batson, Joshua, Botvinnik, Olga, Chen, Michelle B., Chen, Steven, Green, Foad, Jones, Robert, Maynard, Ashley, Penland, Lolita, Pisco, Angela Oliveira, Sit, Rene V., Stanley, Geoffrey M., Webber, James T., Zanini, Fabio, Baghel, Ankit S, Bakerman, Isaac, Bansal, Ishita, Berdnik, Daniela, Bilen, Biter, Brownfield, Douglas, Cain, Corey, Cho, Min, Cirolia, Giana, Conley, Stephanie D., Darmanis, Spyros, Demers, Aaron, Demir, Kubilay, de Morree, Antoine, Divita, Tessa, du Bois, Haley, Dulgeroff, Laughing Bear Torrez, Ebadi, Hamid, Espinoza, F. Hernán, Fish, Matt, Gan, Qiang, George, Benson M., Gillich, Astrid, Genetiano, Geraldine, Gu, Xueying, Gulati, Gunsagar S., Hang, Yan, Hosseinzadeh, Shayan, Huang, Albin, Iram, Tal, Isobe, Taichi, Ives, Feather, Kao, Kevin S., Karnam, Guruswamy, Kershner, Aaron M., Kiss, Bernhard M., Kong, William, Kumar, Maya E., Lam, Jonathan, Lee, Davis P., Lee, Song E., Li, Guang, Li, Qingyun, Liu, Ling, Lo, Annie, Lu, Wan-Jin, Manjunath, Anoop, May, Kaia L., May, Oliver L., McKay, Marina, Metzger, Ross J., Mignardi, Marco, Min, Dullei, Nabhan, Ahmad N., Ng, Katharine M., Noh, Joseph, Patkar, Rasika, Peng, Weng Chuan, Puccinelli, Robert, Rulifson, Eric J., Sikandar, Shaheen S., Sinha, Rahul, Szade, Krzysztof, Tan, Weilun, Tato, Cristina, Tellez, Krissie, Travaglini, Kyle J., Tropini, Carolina, Waldburger, Lucas, van Weele, Linda J., Wosczyna, Michael N., Xiang, Jinyi, Xue, Soso, Youngyunpipatkul, Justin, Zardeneta, Macy E., Zhang, Fan, Zhou, Lu, oungyunpipatkul, Justin Y, Castro, Paola, Croote, Derek

Volltext

Ageing hallmarks exhibit organ-specific temporal signatures von Schaum, Nicholas, Lehallier, Benoit, Hahn, Oliver, Pálovics, Róbert, Hosseinzadeh, Shayan, Lee, Song E., Sit, Rene, Lee, Davis P., Losada, Patricia Morán, Zardeneta, Macy E., Fehlmann, Tobias, Webber, James T., McGeever, Aaron, Calcuttawala, Kruti, Zhang, Hui, Berdnik, Daniela, Mathur, Vidhu, Tan, Weilun, Zee, Alexander, Tan, Michelle, Pisco, Angela Oliveira, Karkanias, Jim, Neff, Norma F., Keller, Andreas, Darmanis, Spyros, Quake, Stephen R., Wyss-Coray, Tony

Volltext

Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids von Marsee, Ary, Roos, Floris J.M., Verstegen, Monique M.A., Marsee, Ary, Roos, Floris, Verstegen, Monique, Clevers, Hans, Vallier, Ludovic, Takebe, Takanori, Huch, Meritxell, Peng, Weng Chuan, Forbes, Stuart, Lemaigre, Frédéric, de Koning, Eelco, Gehart, Helmuth, van der Laan, Luc, Spee, Bart, Boj, Sylvia, Baptista, Pedro, Schneeberger, Kerstin, Soroka, Carol, Heim, Markus, Nuciforo, Sandro, Zaret, Kenneth, Saito, Yoshimasa, Lutolf, Matthias, Cardinale, Vincenzo, Simons, Ben, van IJzendoorn, Sven, Kamiya, Akihide, Chikada, Hiromi, Wang, Shuyong, Mun, Seon Ju, Son, Myung Jin, Onder, Tamer Tevfik, Boyer, James, Sato, Toshiro, Georgakopoulos, Nikitas, Meneses, Andre, Broutier, Laura, Boulter, Luke, Grün, Dominic, IJzermans, Jan, Artegiani, Benedetta, van Boxtel, Ruben, Kuijk, Ewart, Carpino, Guido, Peltz, Gary, Banales, Jesus, Man, Nancy, Aloia, Luigi, LaRusso, Nicholas, George, Gregory, Rimland, Casey, Yeoh, George, Grappin-Botton, Anne, Stange, Daniel, Prior, Nicole, Tirnitz-Parker, Janina E.E., Andersson, Emma, Braconi, Chiara, Hannan, Nicholas, Lu, Wei-Yu, Strom, Stephen, Sancho-Bru, Pau, Ogawa, Shinichiro, Corbo, Vincenzo, Lancaster, Madeline, Hu, Huili, Fuchs, Sabine, Hendriks, Delilah, Gehart, Helmuth, de Koning, Eelco, Lemaigre, Frédéric, Forbes, Stuart J., Peng, Weng Chuan, Huch, Meritxell, Takebe, Takanori, Vallier, Ludovic, Clevers, Hans, van der Laan, Luc J.W., Spee, Bart

Volltext

Molecular hallmarks of heterochronic parabiosis at single-cell resolution von Pálovics, Róbert, Keller, Andreas, Schaum, Nicholas, Tan, Weilun, Fehlmann, Tobias, Borja, Michael, Kern, Fabian, Bonanno, Liana, Calcuttawala, Kruti, Webber, James, McGeever, Aaron, Luo, Jian, Pisco, Angela Oliveira, Karkanias, Jim, Neff, Norma F., Darmanis, Spyros, Quake, Stephen R., Wyss-Coray, Tony

Volltext

Inflammatory Cytokine TNFα Promotes the Long-Term Expansion of Primary Hepatocytes in 3D Culture von Peng, Weng Chuan, Logan, Catriona Y., Fish, Matt, Anbarchian, Teni, Aguisanda, Francis, Álvarez-Varela, Adrián, Wu, Peng, Jin, Yinhua, Zhu, Junjie, Li, Bin, Grompe, Markus, Wang, Bruce, Nusse, Roel

Volltext

Wnt signaling regulates hepatocyte cell division by a transcriptional repressor cascade von Jin, Yinhua, Anbarchian, Teni, Wu, Peng, Sarkar, Abby, Fish, Matt, Peng, Weng Chuan, Nusse, Roel

Volltext

SAT-228 - Infiltrating suppressive myeloid cells dominate the pediatric hepatoblastoma tumor immune microenvironment von Krijgsman, Danielle, Kraaier, Lianne, Verdonschot, Meggy, Leusen, Jeanette, Peng, Weng Chuan, Vercoulen, Yvonne

Volltext

Infiltrating suppressive myeloid cells dominate the pediatric hepatoblastoma tumor immune microenvironment von Krijgsman, Danielle, Kraaier, Lianne, Verdonschot, Meggy, Leusen, Jeanette, Peng, Weng Chuan, Vercoulen, Yvonne

Volltext

Long-Term Expansion of Murine Primary Hepatocyte Organoids von Kluiver, Thomas A., Kraaier, Lianne J., Peng, Weng Chuan

Volltext