A TALEN Genome-Editing System for Generating Human Stem Cell-Based Disease Models von Ding, Qiurong, Lee, Youn-Kyoung, Schaefer, Esperance A.K., Peters, Derek T., Veres, Adrian, Kim, Kevin, Kuperwasser, Nicolas, Motola, Daniel L., Meissner, Torsten B., Hendriks, William T., Trevisan, Marta, Gupta, Rajat M., Moisan, Annie, Banks, Eric, Friesen, Max, Schinzel, Robert T., Xia, Fang, Tang, Alexander, Xia, Yulei, Figueroa, Emmanuel, Wann, Amy, Ahfeldt, Tim, Daheron, Laurence, Zhang, Feng, Rubin, Lee L., Peng, Lee F., Chung, Raymond T., Musunuru, Kiran, Cowan, Chad A.

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IL28B inhibits hepatitis C virus replication through the JAK–STAT pathway von Zhang, Leiliang, Jilg, Nikolaus, Shao, Run-Xuan, Lin, Wenyu, Fusco, Dahlene N, Zhao, Hong, Goto, Kaku, Peng, Lee F, Chen, Wen-Chi, Chung, Raymond T

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HCV induces transforming growth factor β1 through activation of endoplasmic reticulum stress and the unfolded protein response von Chusri, Pattranuch, Kumthip, Kattareeya, Hong, Jian, Zhu, Chuanlong, Duan, Xiaoqiong, Jilg, Nikolaus, Fusco, Dahlene N., Brisac, Cynthia, Schaefer, Esperance A., Cai, Dachuan, Peng, Lee F., Maneekarn, Niwat, Lin, Wenyu, Chung, Raymond T.

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Hepatitis C Virus NS5A Disrupts STAT1 Phosphorylation and Suppresses Type I Interferon Signaling von KUMTHIP, Kattareeya, CHUSRI, Pattranuch, PANTIP, Chansom, THONGSAWAT, Satawat, O'BRIEN, Amornrat, PENG, Lee F, MANEEKARN, Niwat, CHUNG, Raymond T, WENYU LIN, JILG, Nikolaus, LEI ZHAO, FUSCO, Dahlene N, HONG ZHAO, GOTO, Kaku, DU CHENG, SCHAEFER, Esperance A, LEILIANG ZHANG

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Syntheses of aminoalcohol-derived macrocycles leading to a small-molecule binder to and inhibitor of Sonic Hedgehog von Peng, Lee F., Stanton, Benjamin Z., Maloof, Nicole, Wang, Xiang, Schreiber, Stuart L.

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A Cell-Based, High-Throughput Screen for Small Molecule Regulators of Hepatitis C Virus Replication von Kim, Sun Suk, Peng, Lee F, Lin, Wenyu, Choe, Won-Hyeok, Sakamoto, Naoya, Schreiber, Stuart L, Chung, Raymond T

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Suppressor of Cytokine Signaling 3 Suppresses Hepatitis C Virus Replication in an mTOR-Dependent Manner von Shao, Run-Xuan, Zhang, Leiliang, Peng, Lee F, Sun, Eileen, Chung, Woo Jin, Jang, Jae Yong, Tsai, Wei-Lun, Hyppolite, Guibenson, Chung, Raymond T

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A small molecule that directs differentiation of human ESCs into the pancreatic lineage von Melton, Douglas, Chen, Shuibing, Borowiak, Malgorzata, Fox, Julia L, Maehr, René, Osafune, Kenji, Davidow, Lance, Lam, Kelvin, Peng, Lee F, Schreiber, Stuart L, Rubin, Lee L

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Small-molecule modulators of the Sonic Hedgehog signaling pathway von Stanton, Benjamin Z, Peng, Lee F

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Apolipoprotein B100 is required for hepatitis C infectivity and Mipomersen inhibits hepatitis C von Schaefer, Esperance A K, Meixiong, James, Mark, Christina, Deik, Amy, Motola, Daniel L, Fusco, Dahlene, Yang, Andrew, Brisac, Cynthia, Salloum, Shadi, Lin, Wenyu, Clish, Clary B, Peng, Lee F, Chung, Raymond T

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A functional genomic screen identifies cellular cofactors of hepatitis C virus replication von Tai, Andrew W, Benita, Yair, Peng, Lee F, Kim, Sun-Suk, Sakamoto, Naoya, Xavier, Ramnik J, Chung, Raymond T

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Kinetic differences in the induction of interferon stimulated genes by interferon‐α and interleukin 28B are altered by infection with hepatitis C virus von Jilg, Nikolaus, Lin, Wenyu, Hong, Jian, Schaefer, Esperance A., Wolski, David, Meixong, James, Goto, Kaku, Brisac, Cynthia, Chusri, Pattranuch, Fusco, Dahlene N., Chevaliez, Stephane, Luther, Jay, Kumthip, Kattareeya, Urban, Thomas J., Peng, Lee F., Lauer, Georg M., Chung, Raymond T.

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Hepatitis C Virus Regulates Transforming Growth Factor β1 Production Through the Generation of Reactive Oxygen Species in a Nuclear Factor κB–Dependent Manner von Lin, Wenyu, Tsai, Wei–Lun, Shao, Run–Xuan, Wu, Guoyang, Peng, Lee F, Barlow, Lydia L, Chung, Woo Jin, Zhang, Leiliang, Zhao, Hong, Jang, Jae–Young, Chung, Raymond T

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A small molecule that binds Hedgehog and blocks its signaling in human cells von Peng, Lee F, Schreiber, Stuart L, Stanton, Benjamin Z, Maloof, Nicole, Nakai, Kazuo, Wang, Xiang, Duffner, Jay L, Taveras, Kennedy M, Hyman, Joel M, Lee, Sam W, Koehler, Angela N, Chen, James K, Fox, Julia L, Mandinova, Anna

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EFTUD2 Is a Novel Innate Immune Regulator Restricting Hepatitis C Virus Infection through the RIG-I/MDA5 Pathway von Zhu, Chuanlong, Xiao, Fei, Hong, Jian, Wang, Kun, Liu, Xiao, Cai, Dachuan, Fusco, Dahlene N, Zhao, Lei, Jeong, Soung Won, Brisac, Cynthia, Chusri, Pattranuch, Schaefer, Esperance A, Zhao, Hong, Peng, Lee F, Lin, Wenyu, Chung, Raymond T

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A novel NEDD4L-TXNIP-CHOP axis in the pathogenesis of nonalcoholic steatohepatitis von Guo, Qian, Xin, Mingyang, Lu, Qingchun, Feng, Dechun, Yang, Vicky, Peng, Lee F, Whelan, Kelly A, Hu, Wenhui, Wu, Sheng, Yang, Xiaofeng, Wang, Hong, Rothberg, Brad S, Gamero, Ana M, Gerhard, Glenn S, Gao, Bin, Yang, Ling

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HIV and HCV Cooperatively Promote Hepatic Fibrogenesis via Induction of Reactive Oxygen Species and NFκB von Lin, Wenyu, Wu, Guoyang, Li, Shaoyong, Weinberg, Ethan M., Kumthip, Kattareeya, Peng, Lee F., Méndez-Navarro, Jorge, Chen, Wen-Chi, Jilg, Nikolaus, Zhao, Hong, Goto, Kaku, Zhang, Leiliang, Brockman, Mark A., Schuppan, Detlef, Chung, Raymond T.

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The spliceosome factor SART1 exerts its anti-HCV action through mRNA splicing von Lin, Wenyu, Zhu, Chuanlong, Hong, Jian, Zhao, Lei, Jilg, Nikolaus, Fusco, Dahlene N, Schaefer, Esperance A, Brisac, Cynthia, Liu, Xiao, Peng, Lee F, Xu, Qikai, Chung, Raymond T

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HIV Increases HCV Replication in a TGF-β1–Dependent Manner von Lin, Wenyu, Weinberg, Ethan M, Tai, Andrew W, Peng, Lee F, Brockman, Mark A, Kim, Kyung–Ah, Kim, Sun Suk, Borges, Carolina B, Shao, Run–Xuan, Chung, Raymond T

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Small-molecule modulators of the Sonic Hedgehog signaling pathway von Stanton, Benjamin Z., Peng, Lee F.

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