Combined targeted therapy and immunotherapy in melanoma: a review of the impact on the tumor microenvironment and outcomes of early clinical trials von Pelster, Meredith S., Amaria, Rodabe N.

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Post-therapy emergence of an NBN reversion mutation in a patient with pancreatic acinar cell carcinoma von Pelster, Meredith S., Silverman, Ian M., Schonhoft, Joseph D., Johnson, Adrienne, Selenica, Pier, Ulanet, Danielle, Rimkunas, Victoria, Reis-Filho, Jorge S.

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Adagrasib with or without Cetuximab in Colorectal Cancer with Mutated KRAS G12C von Yaeger, Rona, Weiss, Jared, Pelster, Meredith S., Spira, Alexander I., Barve, Minal, Ou, Sai-Hong I., Leal, Ticiana A., Bekaii-Saab, Tanios S., Paweletz, Cloud P., Heavey, Grace A., Christensen, James G., Velastegui, Karen, Kheoh, Thian, Der-Torossian, Hirak, Klempner, Samuel J.

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Nivolumab and Ipilimumab in Metastatic Uveal Melanoma: Results From a Single-Arm Phase II Study von Pelster, Meredith S, Gruschkus, Stephen K, Bassett, Roland, Gombos, Dan S, Shephard, Michael, Posada, Liberty, Glover, Maura S, Simien, Rinata, Diab, Adi, Hwu, Patrick, Carter, Brett W, Patel, Sapna P

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Adagrasib in Advanced Solid Tumors Harboring a KRASG12C Mutation von Bekaii-Saab, Tanios S, Yaeger, Rona, Spira, Alexander I, Pelster, Meredith S, Sabari, Joshua K, Hafez, Navid, Barve, Minal, Velastegui, Karen, Yan, Xiaohong, Shetty, Aditya, Der-Torossian, Hirak, Pant, Shubham

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Pembrolizumab‐induced mucositis in a patient with recurrent hypopharynx squamous cell cancer von Pelster, Meredith S., Mott, Frank, Lewin, Jan

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Neoadjuvant Immunotherapy for Locally Advanced Melanoma von Pelster, Meredith S., Amaria, Rodabe N.

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Adagrasib in Advanced Solid Tumors Harboring a KRAS G12C Mutation von Bekaii-Saab, Tanios S, Yaeger, Rona, Spira, Alexander I, Pelster, Meredith S, Sabari, Joshua K, Hafez, Navid, Barve, Minal, Velastegui, Karen, Yan, Xiaohong, Shetty, Aditya, Der-Torossian, Hirak, Pant, Shubham

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Pembrolizumab-induced mucositis in a patient with recurrent hypopharynx squamous cell cancer von Pelster, Meredith S, Mott, Frank, Lewin, Jan

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ONCX-NAV-G201: A phase 2 basket study of navicixizumab monotherapy or in combination with chemotherapy in patients with select advanced solid tumors—Colorectal Cancer Cohort (trial... von Oberstein, Paul Eliezer, Pelster, Meredith, Culm, Kerry, Chamberlain Santos, Valerie, Koustenis, Andrew, Mockbee, Colleen M., Youssoufian, Hagop, Krauss, John C.

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A multicenter, open-label, phase 1a/b study of HC-7366, a modulator of integrated stress response (ISR) kinase GCN2 in subjects with advanced solid tumors von Pelster, Meredith, Torre, Marcio, Kannan, Geoffrey Sumithran, Gargano, Michele Anne, Mattson, Paulette, Rathmann, Blaine, Bose, Nandita, Iglesias, Jose Luis

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Tumor infiltrating lymphocyte (TIL) harvest and ex vivo expansion from primary and metastatic (met) uveal melanoma (UM) tumors von Patel, Sapna Pradyuman, Forget, Marie-Andree, Kreidieh, Firas Y., Pelster, Meredith, Davies, Michael A., Amaria, Rodabe Navroze, Gombos, Dan S., Bernatchez, Chantale

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Preliminary results of a phase 1/2, first-in-human, open-label, dose escalation study of ZL-1211 (anti-Claudin 18.2 mAb) in patients with unresectable or metastatic solid tumors von Sharma, Sunil, Starodub, Alexander, Xu, Nong, Chaudhry, Arvind, Sun, Meili, Pelster, Meredith, Fu, Yinjia, Zhang, Xinyu, Huang, Zhao, Liu, Wenyu, Hsu, Karl

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A phase 1/2, first-in-human trial of ZB131, a novel antibody targeting cancer-specific plectin (CSP) in advanced solid tumors von Sommerhalder, David, Piha-Paul, Sarina A., Pelster, Meredith, Borad, Mitesh J., Vandross, Andrae Lavon, Spira, Alexander I., Perez, Samantha, Brinton, Lindsey, Kelly, Kimberly, Ramanathan, Ramesh K., Reilley, Matthew

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KRYSTAL-1: Activity and safety of adagrasib (MRTX849) in patients with advanced solid tumors harboring a KRAS G12C mutation von Pant, Shubham, Yaeger, Rona, Spira, Alexander I., Pelster, Meredith, Sabari, Joshua K., Hafez, Navid, Barve, Minal A., Velastegui, Karen, Yan, Xiaohong, Der-Torossian, Hirak, Bekaii-Saab, Tanios S.

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EDGE-Gastric Arm A1: Phase 2 study of domvanalimab, zimberelimab, and FOLFOX in first-line (1L) advanced gastroesophageal cancer von Janjigian, Yelena Y., Oh, Do-Youn, Pelster, Meredith, Wainberg, Zev A., Sison, Edward Allan R., Scott, Jennifer R., Ronayne, Jack, Wishengrad, Dana, Rhee, Joon, Nuyten, Dimitry S. A., Rha, Sun Young

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A phase 1/2 study of REGN7075 (EGFRxCD28 costimulatory bispecific antibody) in combination with cemiplimab (anti–PD-1) in patients with advanced solid tumors: Trial-in-progress upd... von Segal, Neil Howard, Pelster, Meredith, Girda, Eugenia, Fong, Lawrence, Olszanski, Anthony J., Han, Hyunsil, Casey, Kerry A., Li, Siyu, Welf, Erik, Chen, Chieh-I, Skokos, Dimitris, Seebach, Frank A., Lowy, Israel, Fury, Matthew G., Mathias, Melissa Divya, Lakhani, Nehal J.

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Trial in progress: A phase 1, first-in-human, open-label, multicenter, dose-escalation and dose-expansion study of ASP3082 in patients with previously treated advanced solid tumors... von Tolcher, Anthony W., Park, Wungki, Wang, Judy S., Spira, Alexander I., Janne, Pasi A., Lee, Ho-Jin, Gill, Stanley, LoRusso, Patricia, Herzberg, Benjamin, Goldman, Jonathan W., Morgensztern, Daniel, Berlin, Jordan, Kasi, Anup, Fujii, Hisaki, Pelster, Meredith

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611 XTX202–01/02–001, Phase 1/2 first-in human study of XTX202, a masked, tumor-activated IL-2βγ, in patients with advanced solid tumors: results from phase 1 von Hanna, Diana, Zakharia, Yousef, Goel, Sanjay, Hurley, Randy, Pelster, Meredith, El-Khoueiry, Anthony, Thomas, Jacob, Powderly, John, Miller, David, Wu, Richard, Chmielowski, Bartosz, Rapisuwon, Suthee, Gupta, Anurag, Duncan, Meghan, Siu, Aika, Patel, Ekta, Fantini, Damiano, Crowe, David, Paramasivan, Sattanathan, Lee, George, Luptakova, Katarina, McKean, Meredith

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80. Identification of a post-platinum NBN reversion in a pancreatic cancer patient with a co-occurring NTRK1 fusion von Johnson, Adrienne, Selenica, Pier, Schonhoft, Joseph, Ulanet, Danielle, Rimkunas, Victoria, Reis-Filho, Jorge, Silverman, Ian, Pelster, Meredith

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