Dynamics and Location of the Allosteric Midazolam Site in Cytochrome P4503A4 in Lipid Nanodiscs von Redhair, Michelle, Hackett, John C, Pelletier, Robert D, Atkins, William M

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Improved methods for the detection of heme and protoporphyrin IX adducts and quantification of heme B from cytochrome P450 containing systems von Pelletier, Robert D, Rettie, Allan E, Kowalski, John P

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Design and Characterization of the First Selective and Potent Mechanism-Based Inhibitor of Cytochrome P450 4Z1 von Kowalski, John P, McDonald, Matthew G, Pelletier, Robert D, Hanenberg, Helmut, Wiek, Constanze, Rettie, Allan E

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Application of a Substrate Cocktail Approach in the Assessment of Cytochrome P450 Induction Using Cultured Human Hepatocytes von Pelletier, Robert D., Lai, W. George, Wong, Y. Nancy

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Preferential inducibility of CYP1A1 and CYP1A2 by TCDD: Differential regulation in primary human hepatocytes versus transformed human cells von Zhang, Zhi-Yi, Pelletier, Robert D., Wong, Y. Nancy, Sugawara, Michiko, Zhao, Nanding, Littlefield, Bruce A.

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Mechanisms of Herb-Drug Interactions Involving Cinnamon and CYP2A6: Focus on Time-Dependent Inhibition by Cinnamaldehyde and 2-Methoxycinnamaldehyde von Espiritu, Michael J., Chen, Justin, Yadav, Jaydeep, Larkin, Michael, Pelletier, Robert D., Chan, Jeannine M., Jeevan, B. G. C., Natesan, Senthil, Harrelson, John P.

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Pharmacokinetic characterization of a natural product–inspired novel MEK1 inhibitor E6201 in preclinical species von Kumar, Vipul, Schuck, Edgar L., Pelletier, Robert D., Farah, Nadia, Condon, Krista B., Ye, Meng, Rowbottom, Christopher, King, Belinda M., Zhang, Zhi-Yi, Saxton, Philip L., Wong, Y. Nancy

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Abstract 2570: Discovery of potent, selective, and orally available WEE1 inhibitors that demonstrate increased DNA damage and mitosis in tumor cells leading to tumor regression in... von Sun, Shaoxian, Silvergleid, Sarah, Gerasyuto, Aleksey I., Wang, Jiashi, Pelletier, Robert D., Placzek, Andrew, Knight, Jennifer L., Clark, Anthony, Wright, Hamish, Yin, Wu, Elk, Jackson Chief, Bell, Jeff, Bos, Pieter H., Boyles, Nicholas A., Therrien, Eric, Jensen, Kristian, Akinsanya, Karen

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LEC1 sequentially regulates the transcription of genes involved in diverse developmental processes during seed development von Pelletier, Julie M., Kwong, Raymond W., Park, Soomin, Le, Brandon H., Baden, Russell, Cagliari, Alexandro, Hashimoto, Meryl, Munoz, Matthew D., Fischer, Robert L., Goldberg, Robert B., Harada, John J.

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Comprehensive developmental profiles of gene activity in regions and subregions of the Arabidopsis seed von Belmonte, Mark F, Kirkbride, Ryan C, Stone, Sandra L, Pelletier, Julie M, Bui, Anhthu Q, Yeung, Edward C, Hashimoto, Meryl, Fei, Jiong, Harada, Corey M, Munoz, Matthew D, Le, Brandon H, Drews, Gary N, Brady, Siobhan M, Goldberg, Robert B, Harada, John J

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Unique Structural Modifications Are Present in the Lipopolysaccharide from Colistin-Resistant Strains of Acinetobacter baumannii von PELLETIER, Mark R, CASELLA, Leila G, JONES, Jace W, ADAMS, Mark D, ZURAWSKI, Daniel V, HAZLETT, Karsten R. O, DOI, Yohei, ERNST, Robert K

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The distribution of manta rays in the western North Atlantic Ocean off the eastern United States von Farmer, Nicholas A., Garrison, Lance P., Horn, Calusa, Miller, Margaret, Gowan, Timothy, Kenney, Robert D., Vukovich, Michelle, Willmott, Julia Robinson, Pate, Jessica, Harry Webb, D., Mullican, Timothy J., Stewart, Joshua D., Bassos-Hull, Kim, Jones, Christian, Adams, Delaney, Pelletier, Nicole A., Waldron, Jordan, Kajiura, Stephen

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eIF4A supports an oncogenic translation program in pancreatic ductal adenocarcinoma von Chan, Karina, Robert, Francis, Oertlin, Christian, Kapeller-Libermann, Dana, Avizonis, Daina, Gutierrez, Johana, Handly-Santana, Abram, Doubrovin, Mikhail, Park, Julia, Schoepfer, Christina, Da Silva, Brandon, Yao, Melissa, Gorton, Faith, Shi, Junwei, Thomas, Craig J., Brown, Lauren E., Porco, John A., Pollak, Michael, Larsson, Ola, Pelletier, Jerry, Chio, Iok In Christine

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Rationally Designed TLR4 Ligands for Vaccine Adjuvant Discovery von Gregg, Kelsey A, Harberts, Erin, Gardner, Francesca M, Pelletier, Mark R, Cayatte, Corinne, Yu, Li, McCarthy, Michael P, Marshall, Jason D, Ernst, Robert K

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LPS remodeling is an evolved survival strategy for bacteria von Li, Yanyan, Powell, Daniel A., Shaffer, Scott A., Rasko, David A., Pelletier, Mark R., Leszyk, John D., Scott, Alison J., Masoudi, Ali, Goodlett, David R., Wang, Xiaoyuan, Raetz, Christian R. H., Ernst, Robert K.

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Discovery of a novel ERK inhibitor with activity in models of acquired resistance to BRAF and MEK inhibitors von Morris, Erick J, Jha, Sharda, Restaino, Clifford R, Dayananth, Priya, Zhu, Hugh, Cooper, Alan, Carr, Donna, Deng, Yongi, Jin, Weihong, Black, Stuart, Long, Brian, Liu, Jenny, Dinunzio, Edward, Windsor, William, Zhang, Rumin, Zhao, Shuxia, Angagaw, Minilik H, Pinheiro, Elaine M, Desai, Jagdish, Xiao, Li, Shipps, Gerald, Hruza, Alan, Wang, James, Kelly, Joe, Paliwal, Sunil, Gao, Xiaolei, Babu, Boga Sobhana, Zhu, Liang, Daublain, Pierre, Zhang, Ling, Lutterbach, Bart A, Pelletier, Marc R, Philippar, Ulrike, Siliphaivanh, Phieng, Witter, David, Kirschmeier, Paul, Bishop, W Robert, Hicklin, Daniel, Gilliland, D Gary, Jayaraman, Lata, Zawel, Leigh, Fawell, Stephen, Samatar, Ahmed A

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Leaflet Thrombosis in Surgically Explanted or Post-Mortem TAVR Valves von Mangione, Fernanda M., MD, Jatene, Tannas, MD, Gonçalves, Alexandra, MD, PhD, MMSc, Fishbein, Gregory A., MD, Mitchell, Richard N., MD, PhD, Pelletier, Marc P., MD, Kaneko, Tsuyoshi, MD, Shah, Pinak B., MD, Nyman, Charles B., MBBCh, Shook, Douglas, MD, Blankstein, Ron, MD, Padera, Robert F., MD, PhD, Bhatt, Deepak L., MD, MPH

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The Roles of Self-Efficacy and Motivation in the Prediction of Short- and Long-Term Adherence to Exercise Among Patients With Coronary Heart Disease von Slovinec D'Angelo, Monika E., Pelletier, Luc G., Reid, Robert D., Huta, Veronika

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Management of the Potential Organ Donor in the ICU: Society of Critical Care Medicine/American College of Chest Physicians/Association of Organ Procurement Organizations Consensus... von Kotloff, Robert M, Blosser, Sandralee, Fulda, Gerard J, Malinoski, Darren, Ahya, Vivek N, Angel, Luis, Byrnes, Matthew C, DeVita, Michael A, Grissom, Thomas E, Halpern, Scott D, Nakagawa, Thomas A, Stock, Peter G, Sudan, Debra L, Wood, Kenneth E, Anillo, Sergio J, Bleck, Thomas P, Eidbo, Elling E, Fowler, Richard A, Glazier, Alexandra K, Gries, Cynthia, Hasz, Richard, Herr, Dan, Khan, Akhtar, Landsberg, David, Lebovitz, Daniel J, Levine, Deborah Jo, Mathur, Mudit, Naik, Priyumvada, Niemann, Claus U, Nunley, David R, O'Connor, Kevin J, Pelletier, Shawn J, Rahman, Omar, Ranjan, Dinesh, Salim, Ali, Sawyer, Robert G, Shafer, Teresa, Sonneti, David, Spiro, Peter, Valapour, Maryam, Vikraman-Sushama, Deepak, Whelan, Timothy P M

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Phase 2 Trial of Ibudilast in Progressive Multiple Sclerosis von Fox, Robert J, Coffey, Christopher S, Conwit, Robin, Cudkowicz, Merit E, Gleason, Trevis, Goodman, Andrew, Klawiter, Eric C, Matsuda, Kazuko, McGovern, Michelle, Naismith, Robert T, Ashokkumar, Akshata, Barnes, Janel, Ecklund, Dixie, Klingner, Elizabeth, Koepp, Maxine, Long, Jeffrey D, Natarajan, Sneha, Thornell, Brenda, Yankey, Jon, Bermel, Robert A, Debbins, Josef P, Huang, Xuemei, Jagodnik, Patricia, Lowe, Mark J, Nakamura, Kunio, Narayanan, Sridar, Sakaie, Ken E, Thoomukuntla, Bhaskar, Zhou, Xiaopeng, Krieger, Stephen, Alvarez, Enrique, Apperson, Michelle, Bashir, Khurram, Cohen, Bruce A, Coyle, Patricia K, Delgado, Silvia, Dewitt, L. Dana, Flores, Angela, Giesser, Barbara S, Goldman, Myla D, Jubelt, Burk, Lava, Neil, Lynch, Sharon G, Moses, Harold, Ontaneda, Daniel, Perumal, Jai S, Racke, Michael, Repovic, Pavle, Riley, Claire S, Severson, Christopher, Shinnar, Shlomo, Suski, Valerie, Weinstock-Guttman, Bianca, Yadav, Vijayshree, Zabeti, Aram

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