Two common disease-associated TYK2 variants impact exon splicing and TYK2 dosage von Li, Zhi, Rotival, Maxime, Patin, Etienne, Michel, Frédérique, Pellegrini, Sandra

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IFNA2: The prototypic human alpha interferon von Paul, Franciane, Pellegrini, Sandra, Uzé, Gilles

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STAT2 is an essential adaptor in USP18-mediated suppression of type I interferon signaling von Arimoto, Kei-ichiro, Löchte, Sara, Stoner, Samuel A, Burkart, Christoph, Zhang, Yue, Miyauchi, Sayuri, Wilmes, Stephan, Fan, Jun-Bao, Heinisch, Jürgen J, Li, Zhi, Yan, Ming, Pellegrini, Sandra, Colland, Frédéric, Piehler, Jacob, Zhang, Dong-Er

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Mycolactone subverts immunity by selectively blocking the Sec61 translocon von Baron, Ludivine, Paatero, Anja Onerva, Morel, Jean-David, Impens, Francis, Guenin-Macé, Laure, Saint-Auret, Sarah, Blanchard, Nicolas, Dillmann, Rabea, Niang, Fatoumata, Pellegrini, Sandra, Taunton, Jack, Paavilainen, Ville O, Demangel, Caroline

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ISG15 deficiency and increased viral resistance in humans but not mice von Speer, Scott D., Li, Zhi, Buta, Sofija, Payelle-Brogard, Béatrice, Qian, Li, Vigant, Frederic, Rubino, Erminia, Gardner, Thomas J., Wedeking, Tim, Hermann, Mark, Duehr, James, Sanal, Ozden, Tezcan, Ilhan, Mansouri, Nahal, Tabarsi, Payam, Mansouri, Davood, Francois-Newton, Véronique, Daussy, Coralie F., Rodriguez, Marisela R., Lenschow, Deborah J., Freiberg, Alexander N., Tortorella, Domenico, Piehler, Jacob, Lee, Benhur, García-Sastre, Adolfo, Pellegrini, Sandra, Bogunovic, Dusan

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A partial form of inherited human USP18 deficiency underlies infection and inflammation von Martin-Fernandez, Marta, Buta, Sofija, Le Voyer, Tom, Li, Zhi, Dynesen, Lasse Toftdal, Vuillier, Françoise, Franklin, Lina, Ailal, Fatima, Muglia Amancio, Alice, Malle, Louise, Gruber, Conor, Benhsaien, Ibtihal, Altman, Jennie, Taft, Justin, Deswarte, Caroline, Roynard, Manon, Nieto-Patlan, Alejandro, Moriya, Kunihiko, Rosain, Jérémie, Boddaert, Nathalie, Bousfiha, Aziz, Crow, Yanick J, Jankovic, Dragana, Sher, Alan, Casanova, Jean-Laurent, Pellegrini, Sandra, Bustamante, Jacinta, Bogunovic, Dusan

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USP18-based negative feedback control is induced by type I and type III interferons and specifically inactivates interferon α response von François-Newton, Véronique, Magno de Freitas Almeida, Gabriel, Payelle-Brogard, Béatrice, Monneron, Danièle, Pichard-Garcia, Lydiane, Piehler, Jacob, Pellegrini, Sandra, Uzé, Gilles

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Receptor dimerization dynamics as a regulatory valve for plasticity of type I interferon signaling von Wilmes, Stephan, Beutel, Oliver, Li, Zhi, Francois-Newton, Véronique, Richter, Christian P, Janning, Dennis, Kroll, Cindy, Hanhart, Patrizia, Hötte, Katharina, You, Changjiang, Uzé, Gilles, Pellegrini, Sandra, Piehler, Jacob

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USP18 and ISG15 coordinately impact on SKP2 and cell cycle progression von Vuillier, Françoise, Li, Zhi, Commere, Pierre-Henri, Dynesen, Lasse Toftdal, Pellegrini, Sandra

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Evolutionary dynamics of human Toll-like receptors and their different contributions to host defense von Barreiro, Luis B, Ben-Ali, Meriem, Quach, Hélène, Laval, Guillaume, Patin, Etienne, Pickrell, Joseph K, Bouchier, Christiane, Tichit, Magali, Neyrolles, Olivier, Gicquel, Brigitte, Kidd, Judith R, Kidd, Kenneth K, Alcaïs, Alexandre, Ragimbeau, Josiane, Pellegrini, Sandra, Abel, Laurent, Casanova, Jean-Laurent, Quintana-Murci, Lluís

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IFN-I inducible miR-3614-5p targets ADAR1 isoforms and fine tunes innate immune activation von Vuillier, Françoise, Li, Zhi, Black, Iain, Cruciani, Melania, Rubino, Erminia, Michel, Frédérique, Pellegrini, Sandra

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Two rare disease-associated Tyk2 variants are catalytically impaired but signaling competent von Li, Zhi, Gakovic, Milica, Ragimbeau, Josiane, Eloranta, Maija-Leena, Rönnblom, Lars, Michel, Frédérique, Pellegrini, Sandra

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Type I Interferonopathy due to a Homozygous Loss-of-Inhibitory Function Mutation in STAT2 von Zhu, Gaofeng, Badonyi, Mihaly, Franklin, Lina, Seabra, Luis, Rice, Gillian I., Anne-Boland-Auge, Deleuze, Jean-François, El-Chehadeh, Salima, Anheim, Mathieu, de Saint-Martin, Anne, Pellegrini, Sandra, Marsh, Joseph A., Crow, Yanick J., El-Daher, Marie-Therese

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Receptor Density Is Key to the Alpha2/Beta Interferon Differential Activities von Moraga, Ignacio, Harari, Daniel, Schreiber, Gideon, Uzé, Gilles, Pellegrini, Sandra

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Standardized Whole-Blood Transcriptional Profiling Enables the Deconvolution of Complex Induced Immune Responses von Urrutia, Alejandra, Duffy, Darragh, Rouilly, Vincent, Posseme, Céline, Djebali, Raouf, Illanes, Gabriel, Libri, Valentina, Albaud, Benoit, Gentien, David, Piasecka, Barbara, Hasan, Milena, Fontes, Magnus, Quintana-Murci, Lluis, Albert, Matthew L., Abel, Laurent, Alcover, Andres, Astrom, Kalla, Bousso, Philippe, Bruhns, Pierre, Cumano, Ana, Demangel, Caroline, Deriano, Ludovic, Di Santo, James, Dromer, Françoise, Eberl, Gérard, Enninga, Jost, Fellay, Jacques, Freitas, Antonio, Gelpi, Odile, Gomperts-Boneca, Ivo, Hercberg, Serge, Lantz, Olivier, Leclerc, Claude, Mouquet, Hugo, Pellegrini, Sandra, Pol, Stanislas, Rogge, Lars, Sakuntabhai, Anavaj, Schwartz, Olivier, Schwikowski, Benno, Shorte, Spencer, Soumelis, Vassili, Tangy, Frédéric, Tartour, Eric, Toubert, Antoine, Ungeheuer, Marie-Noëlle, Quintana-Murci, Lluis, Albert, Matthew L.

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Genome-wide expression profiling of lymphoblastoid cell lines distinguishes different forms of autism and reveals shared pathways von Nishimura, Yuhei, Martin, Christa L., Vazquez-Lopez, Araceli, Spence, Sarah J., Alvarez-Retuerto, Ana Isabel, Sigman, Marian, Steindler, Corinna, Pellegrini, Sandra, Schanen, N. Carolyn, Warren, Stephen T., Geschwind, Daniel H.

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Human Ubiquitin-Specific Peptidase 18 Is Regulated by microRNAs via the 3'Untranslated Region, A Sequence Duplicated in Long Intergenic Non-coding RNA Genes Residing in chr22q11.21 von Rubino, Erminia, Cruciani, Melania, Tchitchek, Nicolas, Le Tortorec, Anna, Rolland, Antoine D, Veli, Önay, Vallet, Leslie, Gaggi, Giulia, Michel, Frédérique, Dejucq-Rainsford, Nathalie, Pellegrini, Sandra

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Tyk2 and Stat3 Regulate Brown Adipose Tissue Differentiation and Obesity von Derecka, Marta, Gornicka, Agnieszka, Koralov, Sergei B., Szczepanek, Karol, Morgan, Magdalena, Raje, Vidisha, Sisler, Jennifer, Zhang, Qifang, Otero, Dennis, Cichy, Joanna, Rajewsky, Klaus, Shimoda, Kazuya, Poli, Valeria, Strobl, Birgit, Pellegrini, Sandra, Harris, Thurl E., Seale, Patrick, Russell, Aaron P., McAinch, Andrew J., O’Brien, Paul E., Keller, Susanna R., Croniger, Colleen M., Kordula, Tomasz, Larner, Andrew C.

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Altered Immune Phenotypes and HLA-DQB1 Gene Variation in Multiple Sclerosis Patients Failing Interferon β Treatment von Devi-Marulkar, Priyanka, Moraes-Cabe, Carolina, Campagne, Pascal, Corre, Béatrice, Meghraoui-Kheddar, Aida, Bondet, Vincent, Llibre, Alba, Duffy, Darragh, Maillart, Elisabeth, Papeix, Caroline, Pellegrini, Sandra, Michel, Frédérique

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Copy number variations and founder effect underlying complete IL-10Rβ deficiency in Portuguese kindreds von Charbit-Henrion, Fabienne, Bègue, Bernadette, Sierra, Anaïs, Hanein, Sylvain, Stolzenberg, Marie-Claude, Li, Zhi, Pellegrini, Sandra, Garcelon, Nicolas, Jeanpierre, Marc, Neven, Bénédicte, Loge, Isabelle, Picard, Capucine, Rosain, Jérémie, Bustamante, Jacinta, Le Lorc'h, Marc, Pigneur, Bénédicte, Fernandes, Alicia, Rieux-Laucat, Frédéric, Amil Dias, Jorge, Ruemmele, Frank M, Cerf-Bensussan, Nadine

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