Signal Transducer and Activator of Transcription 3 Control of Human T and B Cell Responses von Deenick, Elissa K, Pelham, Simon J, Kane, Alisa, Ma, Cindy S

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Inherited human ITK deficiency impairs IFN-γ immunity and underlies tuberculosis von Ogishi, Masato, Yang, Rui, Rodriguez, Rémy, Golec, Dominic P, Martin, Emmanuel, Philippot, Quentin, Bohlen, Jonathan, Pelham, Simon J, Arias, Andrés Augusto, Khan, Taushif, Ata, Manar, Al Ali, Fatima, Rozenberg, Flore, Kong, Xiao-Fei, Chrabieh, Maya, Laine, Candice, Lei, Wei-Te, Han, Ji Eun, Seeleuthner, Yoann, Kaul, Zenia, Jouanguy, Emmanuelle, Béziat, Vivien, Youssefian, Leila, Vahidnezhad, Hassan, Rao, V Koneti, Neven, Bénédicte, Fieschi, Claire, Mansouri, Davood, Shahrooei, Mohammad, Pekcan, Sevgi, Alkan, Gulsum, Emiroğlu, Melike, Tokgöz, Hüseyin, Uitto, Jouni, Hauck, Fabian, Bustamante, Jacinta, Abel, Laurent, Keles, Sevgi, Parvaneh, Nima, Marr, Nico, Schwartzberg, Pamela L, Latour, Sylvain, Casanova, Jean-Laurent, Boisson-Dupuis, Stéphanie

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Cytokine-Mediated Regulation of Human Lymphocyte Development and Function: Insights from Primary Immunodeficiencies von Tangye, Stuart G, Pelham, Simon J, Deenick, Elissa K, Ma, Cindy S

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Multibatch Cytometry Data Integration for Optimal Immunophenotyping von Ogishi, Masato, Yang, Rui, Gruber, Conor, Zhang, Peng, Pelham, Simon J., Spaan, Andras N., Rosain, Jeremie, Chbihi, Marwa, Han, Ji Eun, Rao, V. Koneti, Kainulainen, Leena, Bustamante, Jacinta, Boisson, Bertrand, Bogunovic, Dusan, Boisson-Dupuis, Stephanie, Casanova, Jean-Laurent

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Elucidating the effects of disease-causing mutations on STAT3 function in autosomal-dominant hyper-IgE syndrome von Pelham, Simon J., MSc, Lenthall, Helen C., MMSc, Deenick, Elissa K., PhD, Tangye, Stuart G., PhD

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STAT5B restrains human B-cell differentiation to maintain humoral immune homeostasis von Pelham, Simon J, Caldirola, Maria Soledad, Avery, Danielle T, Mackie, Joseph, Rao, Geetha, Gothe, Florian, Peters, Timothy J, Guerin, Antoine, Neumann, David, Vokurkova, Doris, Hwa, Vivian, Zhang, Wenming, Lyu, Shu-Chen, Chang, Iris, Manohar, Monali, Nadeau, Kari C, Gaillard, Maria Isabel, Bezrodnik, Liliana, Iotova, Violeta, Zwirner, Norberto Walter, Gutierrez, Mavel, Al-Herz, Waleed, Goodnow, Christopher C, Vargas-Hernández, Alexander, Forbes Satter, Lisa R, Hambleton, Sophie, Deenick, Elissa K, Ma, Cindy S, Tangye, Stuart G

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Human STAT3 variants underlie autosomal dominant hyper-IgE syndrome by negative dominance von Asano, Takaki, Khourieh, Joelle, Zhang, Peng, Rapaport, Franck, Spaan, Andras N., Li, Juan, Lei, Wei-Te, Pelham, Simon J., Hum, David, Chrabieh, Maya, Han, Ji Eun, Guerin, Antoine, Mackie, Joseph, Gupta, Sudhir, Saikia, Biman, Baghdadi, Jamila E., Fadil, Ilham, Bousfiha, Aziz, Habib, Tanwir, Marr, Nico, Ganeshanandan, Luckshman, Peake, Jane, Droney, Luke, Williams, Andrew, Celmeli, Fatih, Hatipoglu, Nevin, Ozcelik, Tayfun, Picard, Capucine, Abel, Laurent, Tangye, Stuart G., Boisson-Dupuis, Stephanie, Zhang, Qian, Puel, Anne, Beziat, Vivien, Casanova, Jean-Laurent, Boisson, Bertrand

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Activating mutations in PIK3CD disrupt the differentiation and function of human and murine CD4+ T cells von Bier, Julia, Rao, Geetha, Payne, Kathryn, Brigden, Henry, French, Elise, Pelham, Simon J., Lau, Anthony, Lenthall, Helen, Edwards, Emily S.J., Smart, Joanne M., Cole, Theresa S., Choo, Sharon, Joshi, Avni Y., Abraham, Roshini S., O'Sullivan, Michael, Boztug, Kaan, Meyts, Isabelle, Gray, Paul E., Berglund, Lucinda J., Hsu, Peter, Wong, Melanie, Holland, Steven M., Notarangelo, Luigi D., Uzel, Gulbu, Ma, Cindy S., Brink, Robert, Tangye, Stuart G., Deenick, Elissa K.

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Biochemically deleterious human NFKB1 variants underlie an autosomal dominant form of common variable immunodeficiency von Li, Juan, Lei, Wei-Te, Zhang, Peng, Rapaport, Franck, Seeleuthner, Yoann, Lyu, Bingnan, Asano, Takaki, Rosain, Jeremie, Hammadi, Boualem, Zhang, Yu, Pelham, Simon J., Spaan, Andras N., Migaud, Melanie, Hum, David, Bigio, Benedetta, Chrabieh, Maya, Beziat, Vivien, Bustamante, Jacinta, Zhang, Shen-Ying, Jouanguy, Emmanuelle, Boisson-Dupuis, Stephanie, El Baghdadi, Jamila, Aimanianda, Vishukumar, Thoma, Katharina, Fliegauf, Manfred, Grimbacher, Bodo, Korganow, Anne-Sophie, Saunders, Carol, Rao, V. Koneti, Uzel, Gulbu, Freeman, Alexandra F., Holland, Steven M., Su, Helen C., Cunningham-Rundles, Charlotte, Fieschi, Claire, Abel, Laurent, Puel, Anne, Cobat, Aurelie, Casanova, Jean-Laurent, Zhang, Qian, Boisson, Bertrand

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A Novel TRAF3IP2 Mutation Causing Chronic Mucocutaneous Candidiasis von Marujo, Filipa, Pelham, Simon J., Freixo, João, Cordeiro, Ana Isabel, Martins, Catarina, Casanova, Jean-Laurent, Lei, Wei-Te, Puel, Anne, Neves, João Farela

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Impaired development of memory B cells and antibody responses in humans and mice deficient in PD-1 signaling von Ogishi, Masato, Kitaoka, Koji, Good-Jacobson, Kim L, Rinchai, Darawan, Zhang, Baihao, Wang, Jun, Gies, Vincent, Rao, Geetha, Nguyen, Tina, Avery, Danielle T, Khan, Taushif, Smithmyer, Megan E, Mackie, Joseph, Yang, Rui, Arias, Andrés Augusto, Asano, Takaki, Ponsin, Khoren, Chaldebas, Matthieu, Zhang, Peng, Peel, Jessica N, Bohlen, Jonathan, Lévy, Romain, Pelham, Simon J, Lei, Wei-Te, Han, Ji Eun, Fagniez, Iris, Chrabieh, Maya, Laine, Candice, Langlais, David, Gruber, Conor, Al Ali, Fatima, Rahman, Mahbuba, Aytekin, Caner, Benson, Basilin, Dufort, Matthew J, Domingo-Vila, Clara, Moriya, Kunihiko, Shlomchik, Mark, Uzel, Gulbu, Gray, Paul E, Suan, Daniel, Preece, Kahn, Chua, Ignatius, Okada, Satoshi, Chikuma, Shunsuke, Kiyonari, Hiroshi, Tree, Timothy I, Bogunovic, Dusan, Gros, Philippe, Marr, Nico, Speake, Cate, Oram, Richard A, Béziat, Vivien, Bustamante, Jacinta, Abel, Laurent, Boisson, Bertrand, Korganow, Anne-Sophie, Ma, Cindy S, Johnson, Matthew B, Chamoto, Kenji, Boisson-Dupuis, Stéphanie, Honjo, Tasuku, Casanova, Jean-Laurent, Tangye, Stuart G

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Biallelic TRAF3IP2 variants causing chronic mucocutaneous candidiasis in a child harboring a STAT1 variant von Blanco Lobo, Pilar, Lei, Wei‐Te, Pelham, Simon J., Guisado Hernández, Paloma, Villaoslada, Isabel, de Felipe, Beatriz, Lucena, José Manuel, Casanova, Jean‐Laurent, Olbrich, Peter, Puel, Anne, Neth, Olaf, Candotti, Fabio

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Multi-target chimaeric VLP as a therapeutic vaccine in a model of colorectal cancer von Donaldson, Braeden, Al-Barwani, Farah, Pelham, Simon J, Young, Katie, Ward, Vernon K, Young, Sarah L

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NK cells are required for dendritic cell-based immunotherapy at the time of tumor challenge von Bouwer, Anthea L, Saunderson, Sarah C, Caldwell, Felicity J, Damani, Tanvi T, Pelham, Simon J, Dunn, Amy C, Jack, Ralph W, Stoitzner, Patrizia, McLellan, Alexander D

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SARS-CoV-2-related MIS-C: A key to the viral and genetic causes of Kawasaki disease? von Sancho-Shimizu, Vanessa, Brodin, Petter, Cobat, Aurelie, Biggs, Catherine M., Toubiana, Julie, Lucas, Carrie L., Henrickson, Sarah E., Belot, Alexandre, Tangye, Stuart G., Milner, Joshua D., Levin, Michael, Abel, Laurent, Bogunovic, Dusan, Casanova, Jean-Laurent, Zhang, Shen-Ying

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STAT3 mediated regulation of human antibody responses von Pelham, Simon

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Multi-batch cytometry data integration for optimal immunophenotyping von Ogishi, Masato, Yang, Rui, Gruber, Conor, Zhang, Peng, Pelham, Simon J., Spaan, András N., Rosain, Jérémie, Chbihi, Marwa, Han, Ji Eun, Rao, V Koneti, Kainulainen, Leena, Bustamante, Jacinta, Boisson, Bertrand, Bogunovic, Dusan, Boisson-Dupuis, Stéphanie, Casanova, Jean-Laurent

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Inherited human c-Rel deficiency disrupts myeloid and lymphoid immunity to multiple infectious agents von Levy, Romain, Langlais, David, Beziat, Vivien, Rapaport, Franck, Rao, Geetha, Lazarov, Tomi, Bourgey, Mathieu, Zhou, Yu J., Briand, Coralie, Moriya, Kunihiko, Ailal, Fatima, Avery, Danielle T., Markle, Janet, Lim, Ai Ing, Ogishi, Masato, Yang, Rui, Pelham, Simon, Emam, Mehdi, Migaud, Melanie, Deswarte, Caroline, Habib, Tanwir, Saraiva, Luis R., Moussa, Eman A., Guennoun, Andrea, Boisson, Bertrand, Belkaya, Serkan, Martinez-Barricarte, Ruben, Rosain, Jeremie, Belkadi, Aziz, Breton, Sylvain, Payne, Kathryn, Benhsaien, Ibtihal, Plebani, Alessandro, Lougaris, Vassilios, Di Santo, James P., Neven, Benedicte, Abel, Laurent, Ma, Cindy S., Bousfiha, Ahmed Aziz, Marr, Nico, Bustamante, Jacinta, Liu, Kang, Gros, Philippe, Geissmann, Frederic, Tangye, Stuart G., Casanova, Jean-Laurent, Puel, Anne

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Inherited human ITK deficiency impairs IFN-γ immunity and underlies tuberculosis von Ogishi, Masato, Yang, Rui, Rodriguez, Rémy, Golec, Dominic, Martin, Emmanuel, Philippot, Quentin, Bohlen, Jonathan, Pelham, Simon, Arias, Andrés Augusto, Khan, Taushif, Ata, Manar, Al Ali, Fatima, Rozenberg, Flore, Kong, Xiao-Fei, Chrabieh, Maya, Laine, Candice, Lei, Wei-Te, Han, Ji Eun, Seeleuthner, Yoann, Kaul, Zenia, Jouanguy, Emmanuelle, Béziat, Vivien, Youssefian, Leila, Vahidnezhad, Hassan, Rao, V. Koneti, Neven, Bénédicte, Fieschi, Claire, Mansouri, Davood, Shahrooei, Mohammad, Pekcan, Sevgi, Alkan, Gulsum, Emiroğlu, Melike, Tokgöz, Hüseyin, Uitto, Jouni, Hauck, Fabian, Bustamante, Jacinta, Abel, Laurent, Keles, Sevgi, Parvaneh, Nima, Marr, Nico, Schwartzberg, Pamela, Latour, Sylvain, Casanova, Jean-Laurent, Boisson-Dupuis, Stéphanie

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Inherited human ITK deficiency impairs IFN-γ immunity and underlies tuberculosis von Ogishi, Masato, Yang, Rui, Rodriguez, Remy, Golec, Dominic P, Martin, Emmanuel, Philippot, Quentin, Bohlen, Jonathan, Pelham, Simon J, Arias, Andres Augusto, Khan, Taushif, Ata, Manar, Al Ali, Fatima, Rozenberg, Flore, Kong, Xiao-Fei, Chrabieh, Maya, Laine, Candice, Lei, Wei-Te, Han, Ji Eun, Seeleuthner, Yoann, Kaul, Zenia, Jouanguy, Emmanuelle, Beziat, Vivien, Youssefian, Leila, Vahidnezhad, Hassan, Rao, V. Koneti, Neven, Benedicte, Fieschi, Claire, Mansouri, Davood, Shahrooei, Mohammad, Pekcan, Sevgi, Alkan, Gulsum, Emiroglu, Melike, Tokgoez, Hueseyin, Uitto, Jouni, Hauck, Fabian, Bustamante, Jacinta, Abel, Laurent, Keles, Sevgi, Parvaneh, Nima, Marr, Nico, Schwartzberg, Pamela L, Latour, Sylvain, Casanova, Jean-Laurent, Boisson-Dupuis, Stephanie

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