Characterization of the endogenous deoxyribonuclease involved in nuclear DNA degradation during apoptosis (programmed cell death) von Peitsch, M.C., Polzar, B., Stephan, H., Crompton, T., MacDonald, H.R., Mannherz, H.G., Tschopp, J.

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P13-08 Toxicological assessment of nicotine salt in Sprague Dawley rats following subchronic inhalation exposure von Ho, J., Phillips, B.W., Oviedo, A., Leroy, P., Tung, C.K., Yeo, Y.S., Peitsch, M.C., Hoeng, J., Vanscheeuwijck, P.

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Causal biological network model of endothelial dysfunction as a predictor of arterial aging von Astrologo, L., Szostak, J., Talikka, M., Belcastro, V., Peitsch, M.C., Hoeng, J.

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Sharing in the INTERVALS platform study details and data from the assessment of the impact of aerosol from the carbon-heated tobacco product (CHTP) 1.2, a potential modified risk t... von Boue, S., Zanetti, F., Hoeng, J., Peitsch, M.C.

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P19-06 Retrospective histopathology evaluation of respiratory tract tissues from two rat 90-day OECD 413 inhalation studies: Tobacco Heating System 2.2 versus Mentholated Tobacco H... von Oviedo, A., Neves, P.F., Wong, E.T., Foong, C., Vuillaume, G., Sciuscio, D., Peitsch, M.C., Vanscheeuwijck, P.

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Where are we at regarding species translation? A review of the sbv IMPROVER challenge von Hoeng, J, Peitsch, M C, Meyer, P, Jurisica, I

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Biological impact of cigarette smoke compared to an aerosol produced from a prototypic modified risk tobacco product on normal human bronchial epithelial cells von Kogel, U., Gonzalez Suarez, I., Xiang, Y., Dossin, E., Guy, P.A., Mathis, C., Marescotti, D., Goedertier, D., Martin, F., Peitsch, M.C., Hoeng, J.

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Sharing systems toxicology data for inhalation toxicology von Boué, S., Hardy, B., Hayes, W., Belcastro, V., Exner, T., Dokler, J., Hoeng, J., Peitsch, M.C.

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Genomic analysis of L5178Y tk+/− cells and their induced tk−/− mutant colonies von Battey, J.N., Smart, D., Sierro, N.S., Mc Hugh, D., Vanscheeuwijck, P., Peitsch, M.C., Ivanov, N.V.

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A clinical research investigation on the effects of cigarette smoking, e- cigarette vaping and smoking cessation on vascular cell biology von Poussin, C., Spinelli, S.L., Curran, T.M., Baglia, L.A., Berg, R., Ansari, S., Guedj, E., Fedlin medlin, L., Ivanov, N.V., Picavet, P., Phipps, R.P., Peitsch, M.C., Hoeng, J.

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Six-month systems toxicology inhalation/cessation study in ApoE−/− mice to investigate cardiovascular and respiratory exposure effects of two reduced risk products compared with co... von Szostak, J.G., Phillips, B., Emmanuel, G., Wong, E.T., Titz, B., Martin, F., Vuillaume, G., Leroy, P., Buettner, A., Vanscheeuwijck, P., Peitsch, M.C., Hoeng, J.

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Systems toxicology approach for the assessment of zebrafish cardiotoxicity von Li, R., vom Berg, C., Talikka, M., Madan, S., Dörpinghaus, J., Fluck, J., Szostak, J.G., Martin, F., Peitsch, M.C., Hoeng, J., Zupanic, A.

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A comparative high-content screening-based assessment of e-cigarette liquids in primary bronchial epithelial cells von Marescotti, D., Taylor, M., Gonzalez-Suarez, I., Acali, S., Walker, P., Belcastro, V., Martin, F., Frentzel, S., Thorne, D., Peitsch, M.C., Proctor, C., Gaca, M., Hoeng, J.

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Effects of exposure to e-cigarette aerosols compared with cigarette smoke on 3D human buccal and small airway cultures: a systems toxicology assessment von Iskandar, A.R., Sandro, S., Shoaib, M., Kondylis, A., Xiang, Y., Zanetti, F., Frentzel, S., Martin, F., Ivanov, N.V., Peitsch, M.C., Doshi, U., McKinney, W., Lee, M., Hoeng, J.

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Systems toxicology revealed reduced impact of ths 2.2 aerosol relative to 3R4F smoke on aortic smooth muscle cell aging and exacerbation effects in aged cells in vitro von Poussin, C., Van Der Toorn, M., Scheuner, S., Piault, R., Kondylis, A., Savioz, R., Dulize, R., Peric, D., Guedj, E., Maranzano, F., Merg, C., Morelli, M., Egesipe, A.-L., Johne, S., Majeed, S., Pak, C., Schneider, T., Schlage, W.K., Ivanov, N.V., Peitsch, M.C., Hoeng, J.

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3D Vasculature-On-A-Chip: A Model Of Perfused Human Coronary Artery Endothelial Microvessel For Studying Monocyte To Endothelium Adhesion Under Flow von Poussin, C., Kramer, B., Lanz, H., van den Heuvel, A., Laurent, A., Oliver, T., Peric, D., Baumer, K., Dulize, R., Guedj, E., Ivanov, N.V., Peitsch, M.C., Hoeng, J., Joore, J.

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The systems toxicology challenge: Marker of exposure response identification in blood von Poussin, C., Belcastro, V., Boué, S., Martin, F., Sewer, A., Titz, B., Cannesson, L., Peitsch, M.C., Hoeng, J.

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Mutational analysis of polymeric immunoglobulin receptor/ligand interactions. Evidence for the involvement of multiple complementarity determining region (CDR)-like loops in recept... von Coyne, R.S., Siebrecht, M., Peitsch, M.C., Casanova, J.E.

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Systems toxicological assessment of the mentholated Tobacco Heating System 2.2 aerosol revealed reduced cellular and molecular exposure effects compared with cigarette smoke von Kogel, U., Titz, B., Schlage, W.K., Nury, C., Martin, F., Oviedo, A., Lebrun, S., Elamin, A., Guedj, E., Trivedi, K., Ivanov, N.V., Vanscheeuwijck, P., Peitsch, M.C., Hoeng, J.

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Toxicity of aerosols of propylene glycol, vegetable glycerin and nicotine in Sprague-Dawley rats in a 90-d OECD 413 sub-chronic inhalation study von Phillips, B., Sharma, D., Sciuscio, D., Veljkovic, E., Lebrun, S., Verbeeck, J., Tan, W., Kogel, U., Ho, J., Vuillaume, G., Leroy, P., Hoeng, J., Peitsch, M.C., Vanscheeuwijck, P.

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