Oncogene-Induced Cell Senescence — Halting on the Road to Cancer von Mooi, W.J, Peeper, D.S

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Zeb1 is required for TrkB-induced epithelial-mesenchymal transition, anoikis resistance and metastasis von Smit, M A, Peeper, D S

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25: In vivo RNAi screening for novel therapeutic cancer targets von Peeper, D

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BRAF in benign and malignant human tumours von Michaloglou, C, Vredeveld, L C W, Mooi, W J, Peeper, D S

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Presence of a 34-gene signature is a favorable prognostic marker in squamous non-small cell lung carcinoma von Theelen, W. S. M. E., Krijgsman, O., Monkhorst, K., Kuilman, T., Peters, D. D. G. C., Cornelissen, S., Ligtenberg, M. A., Willems, S. M., Blaauwgeers, J. L. G., van Noesel, C. J. M., Peeper, D. S., van den Heuvel, M. M., Schulze, K.

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Survival and biomarker analyses from the OpACIN-neo and OpACIN neoadjuvant immunotherapy trials in stage III melanoma von Rozeman, E. A., Hoefsmit, E. P., Reijers, I. L. M., Saw, R. P. M., Versluis, J. M., Krijgsman, O., Dimitriadis, P., Sikorska, K., van de Wiel, B. A., Eriksson, H., Gonzalez, M., Torres Acosta, A., Grijpink-Ongering, L. G., Shannon, K., Haanen, J. B. A. G., Stretch, J., Ch’ng, S., Nieweg, O. E., Mallo, H. A., Adriaansz, S., Kerkhoven, R. M., Cornelissen, S., Broeks, A., Klop, W. M. C., Zuur, C. L., van Houdt, W. J., Peeper, D. S., Spillane, A. J., van Akkooi, A. C. J., Scolyer, R. A., Schumacher, T. N. M., Menzies, A. M., Long, G. V., Blank, C. U.

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The neurotrophic receptor TrkB: a drug target in anti-cancer therapy? von Desmet, C J, Peeper, D S

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Targeting CDK2 overcomes melanoma resistance against BRAF and Hsp90 inhibitors von Azimi, Alireza, Caramuta, Stefano, Seashore‐Ludlow, Brinton, Boström, Johan, Robinson, Jonathan L, Edfors, Fredrik, Tuominen, Rainer, Kemper, Kristel, Krijgsman, Oscar, Peeper, Daniel S, Nielsen, Jens, Hansson, Johan, Egyhazi Brage, Suzanne, Altun, Mikael, Uhlen, Mathias, Maddalo, Gianluca

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The (re)discovery of tumor-intrinsic determinants of immune sensitivity by functional genetic screens von Vredevoogd, D.W., Apriamashvili, G., Peeper, D.S.

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P12.03 Heterotypic CD8 T cell clusters isolated from clinical samples are distinct and enriched for antitumor activity von Ibáñez Molero, S, Veldman, J, Traets, JJH, George, A, Hoefakker, K, Pack, S, Tas, L, Alóndiga-Mérida, P, van den Broek, B, Harkes, R, Nieuwland, M, van Baalen, M, Mul, E, Tol, S, Haanen, JBAG, Houdt, WJv, Peeper, DS

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Neoadjuvant cytoreductive treatment with BRAF/MEK inhibition of prior unresectable regionally advanced melanoma to allow complete surgical resection, REDUCTOR trial von Blankenstein, S., Rohaan, M.W., Klop, W.M.C., van der Hiel, B., van de Wiel, B., Peeper, D., van Akkooi, A.C.J., Haanen, J.B.A.G.

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Downsizing of locally advanced stage III (bulky) BRAF V600E/K melanoma with combination targeted therapy to achieve R0 resection von Haanen, J, Blank, C, Van Thienen, H, Mallo, H, Adriaansz, S, Ter Meulen, S, Madu, M, Pronk, L, Van der Hiel, B, Van de Wiel, B, Peeper, D, Van Akkooi, A

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Cell cycle-specific association of E2F with the p130 E1A-binding protein von COBRINIK, D, WHYTE, P, PEEPER, D. S, JACKS, T, WEINBERG, R. A

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Ras signalling linked to the cell-cycle machinery by the retinoblastoma protein von Peeper, Daniel S, Upton, Todd M, Ladha, Mohamed H, Neuman, Elizabeth, Zalvide, Juan, Bernards, René, DeCaprio, James A, Ewen, Mark E

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Oncogene-Induced Senescence Relayed by an Interleukin-Dependent Inflammatory Network von Kuilman, Thomas, Michaloglou, Chrysiis, Vredeveld, Liesbeth C.W., Douma, Sirith, van Doorn, Remco, Desmet, Christophe J., Aarden, Lucien A., Mooi, Wolter J., Peeper, Daniel S.

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Escape from premature senescence is not sufficient for oncogenic transformation by Ras von Bernards, René, Peeper, Daniel S, Dannenberg, Jan-Hermen, Douma, Sirith, Riele, Hein te

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PO-512 Gene expression signature comprising distinct stromal and tumor-intrinsic signals predicts response to combined anti-PD1 and anti-CTLA4 checkpoint inhibition von Krijgsman, O, Kemper, K, Rozeman, E, Cornelissen-Steijger, P, Shahrabi, A, Haanen, J, Adams, D, Blank, C, Peeper, D

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1121P Interferon-gamma (IFNy) gene signature as a predictive biomarker for response in lactate dehydrogenase (LDH) low advanced melanoma patients von Hoeijmakers, L., Dimitriadis, P., van Vliet, A., Versluis, J.M., Peeper, D., Blank, C.U.

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A functional screen identifies hDRIL1 as an oncogene that rescues RAS-induced senescence von Bernards, René, Peeper, Daniel S, Shvarts, Avi, Brummelkamp, Thijn, Douma, Sirith, Koh, Eugene Y, Daley, George Q

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Identification of the optimal combination dosing schedule of neoadjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma (OpACIN-neo): a multicentre, phase 2, randomise... von Rozeman, Elisa A, Menzies, Alexander M, van Akkooi, Alexander C J, Adhikari, Chandra, Bierman, Carolien, van de Wiel, Bart A, Scolyer, Richard A, Krijgsman, Oscar, Sikorska, Karolina, Eriksson, Hanna, Broeks, Annegien, van Thienen, Johannes V, Guminski, Alexander D, Acosta, Alex Torres, ter Meulen, Sylvia, Koenen, Anne Miek, Bosch, Linda J W, Shannon, Kerwin, Pronk, Loes M, Gonzalez, Maria, Ch'ng, Sydney, Grijpink-Ongering, Lindsay G, Stretch, Jonathan, Heijmink, Stijn, van Tinteren, Harm, Haanen, John B A G, Nieweg, Omgo E, Klop, Willem M C, Zuur, Charlotte L, Saw, Robyn P M, van Houdt, Winan J, Peeper, Daniel S, Spillane, Andrew J, Hansson, Johan, Schumacher, Ton N, Long, Georgina V, Blank, Christian U

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