Investigation of [11C]carfentanil for mu opioid receptor quantification in the rat brain von Kelleher, Andrew C., Pearson, Torben D., Ramsey, Joseph, Zhao, Wenjing, O’Conor, Kelly A., Bakhoda, Abolghasem, Stodden, Tyler, Guo, Min, Eisenberg, Seth M., Shah, Sarthak V., Freaney, Michael L., Kim, Woochan, Kang, Yeona, Tomasi, Dardo, Johnson, Christopher, Fang, Chung-An, Volkow, Nora D., Kim, Sung Won

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Naloxone’s dose-dependent displacement of [11C]carfentanil and duration of receptor occupancy in the rat brain von Kang, Yeona, O’Conor, Kelly A., Kelleher, Andrew C., Ramsey, Joseph, Bakhoda, Abolghasem, Eisenberg, Seth M., Zhao, Wenjing, Stodden, Tyler, Pearson, Torben D., Guo, Min, Brown, Nina, Liow, Jeih-San, Fowler, Joanna S., Kim, Sung Won, Volkow, Nora D.

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Investigation of 11Ccarfentanil for mu opioid receptor quantification in the rat brain von Kelleher, Andrew C, Pearson, Torben D, Ramsey, Joseph, Zhao, Wenjing, O'Conor, Kelly A, Bakhoda, Abolghasem, Stodden, Tyler, Guo, Min, Eisenberg, Seth M, Shah, Sarthak V, Freaney, Michael L, Kim, Woochan, Kang, Yeona, Tomasi, Dardo, Johnson, Christopher, Fang, Chung-An, Volkow, Nora D, Kim, Sung Won

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Early Restrictive or Liberal Fluid Management for Sepsis-Induced Hypotension von Shapiro, Nathan I, Douglas, Ivor S, Brower, Roy G, Brown, Samuel M, Exline, Matthew C, Ginde, Adit A, Gong, Michelle N, Grissom, Colin K, Hayden, Douglas, Hough, Catherine L, Huang, Weixing, Iwashyna, Theodore J, Jones, Alan E, Khan, Akram, Lai, Poying, Liu, Kathleen D, Miller, Chadwick D, Oldmixon, Katherine, Park, Pauline K, Rice, Todd W, Ringwood, Nancy, Semler, Matthew W, Steingrub, Jay S, Talmor, Daniel, Thompson, B Taylor, Yealy, Donald M, Self, Wesley H

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Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge von Saxena, Richa, Langenberg, Claudia, Tanaka, Toshiko, Vollenweider, Peter, Lyssenko, Valeriya, Bouatia-Naji, Nabila, Jackson, Anne U, Kao, W H Linda, Glazer, Nicole L, Manning, Alisa K, Luan, Jian'an, Stringham, Heather M, Prokopenko, Inga, Johnson, Toby, Grarup, Niels, Boesgaard, Trine W, Lecoeur, Cécile, Shrader, Peter, O'Connell, Jeffrey, Ingelsson, Erik, Couper, David J, Rice, Kenneth, Song, Kijoung, Andreasen, Camilla H, Köttgen, Anna, Le Bacquer, Olivier, Pattou, François, Taneera, Jalal, Steinthorsdottir, Valgerdur, Rybin, Denis, Ardlie, Kristin, Sampson, Michael, Qi, Lu, van Hoek, Mandy, Weedon, Michael N, Voight, Benjamin F, Grallert, Harald, Balkau, Beverley, Bergman, Richard N, Bielinski, Suzette J, Bonnefond, Amelie, Bonnycastle, Lori L, Borch-Johnsen, Knut, Böttcher, Yvonne, Brunner, Eric, Buchanan, Thomas A, Bumpstead, Suzannah J, Cavalcanti-Proença, Christine, Collins, Francis S, Cornelis, Marilyn, J Crawford, Gabriel, Delplanque, Jerome, Doney, Alex, Egan, Josephine M, Erdos, Michael R, Firmann, Mathieu, Forouhi, Nita G, Fox, Caroline S, Goodarzi, Mark O, Graessler, Jürgen, Hingorani, Aroon, Isomaa, Bo, Jørgensen, Torben, Kivimaki, Mika, Kovacs, Peter, Krohn, Knut, Kumari, Meena, Lauritzen, Torsten, Lévy-Marchal, Claire, Mayor, Vladimir, McAteer, Jarred B, Meyre, David, Mitchell, Braxton D, Mohlke, Karen L, Morken, Mario A, Narisu, Narisu, Palmer, Colin N A, Pakyz, Ruth, Pascoe, Laura, Payne, Felicity, Pearson, Daniel, Rathmann, Wolfgang, Sandbaek, Annelli, Sayer, Avan Aihie, Scott, Laura J, Sharp, Stephen J, Sijbrands, Eric, Singleton, Andrew, Siscovick, David S, Smith, Nicholas L, Sparsø, Thomas, Syddall, Holly, Thorleifsson, Gudmar, Tönjes, Anke, Tuomi, Tiinamaija, Tuomilehto, Jaakko, Valle, Timo T, Waeber, Gérard, Zeggini, Eleftheria, Zhao, Jing Hua

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The Association of Cardiometabolic, Diet and Lifestyle Parameters With Plasma Glucagon-like Peptide-1: An IMI DIRECT Study von Eriksen, Rebeca, White, Margaret C, Dawed, Adem Y, Perez, Isabel Garcia, Posma, Joram M, Haid, Mark, Sharma, Sapna, Prehn, Cornelia, Thomas, E Louise, Koivula, Robert W, Bizzotto, Roberto, Mari, Andrea, Giordano, Giuseppe N, Pavo, Imre, Schwenk, Jochen M, De Masi, Federico, Tsirigos, Konstantinos D, Brunak, Søren, Viñuela, Ana, Mahajan, Anubha, McDonald, Timothy J, Kokkola, Tarja, Rutters, Femke, Beulens, Joline, Muilwijk, Mirthe, Blom, Marieke, Elders, Petra, Hansen, Tue H, Fernandez-Tajes, Juan, Jones, Angus, Jennison, Chris, Walker, Mark, McCarthy, Mark I, Pedersen, Oluf, Ruetten, Hartmut, Forgie, Ian, Holst, Jens J, Thomsen, Henrik S, Ridderstråle, Martin, Bell, Jimmy D, Adamski, Jerzy, Franks, Paul W, Hansen, Torben, Holmes, Elaine, Frost, Gary, Pearson, Ewan R

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PET imaging in rat brain shows opposite effects of acute and chronic alcohol exposure on phosphodiesterase-4B, an indirect biomarker of cAMP activity von Tang, Shiyu, Kim, Sung Won, Olsen-Dufour, Amanda, Pearson, Torben, Freaney, Michael, Singley, Erick, Jenkins, Madeline, Burkard, Nathaniel J., Wozniak, Aaron, Parcon, Paul, Wu, Shawn, Morse, Cheryl L., Jana, Susovan, Liow, Jeih-San, Zoghbi, Sami S., Vendruscolo, Janaina C. M., Vendruscolo, Leandro F., Pike, Victor W., Koob, George F., Volkow, Nora D., Innis, Robert B.

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The CTRB1/2 Locus Affects Diabetes Susceptibility and Treatment via the Incretin Pathway von 'T HART, Leen M, FRITSCHE, Andreas, PALMER, Colin N. A, VAN HAEFTEN, Timon W, HERZBERG-SCHÄFER, Silke A, SIMONIS-BIK, Annemarie M. C, HOUWING-DUISTERMAAT, Jeanine J, HELMER, Quinta, DEELEN, Joris, GUIGAS, Bruno, HANSEN, Torben, MACHICAO, Fausto, NIJPELS, Giel, WILLEMSEN, Gonneke, HEINE, Robert J, KRAMER, Mark H. H, HOLST, Jens J, DE KONING, Eelco J. P, HÄRING, Hans-Ulrich, PEDERSEN, Oluf, GROOP, Leif, DE GEUS, Eco J. C, SLAGBOOM, P. Eline, VAN LEEUWEN, Nienke, BOOMSMA, Dorret I, EEKHOFF, Elisabeth M. W, PEARSON, Ewan R, DIAMANT, Michaela, DONNELLY, Louise A, DEKKER, Jacqueline M, ALSSEMA, Marjan, FADISTA, Joao, CARLOTTI, Françoise, GJESING, Anette P

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Processes Underlying Glycemic Deterioration in Type 2 Diabetes: An IMI DIRECT Study von Bizzotto, Roberto, Jennison, Christopher, Jones, Angus G., Kurbasic, Azra, Tura, Andrea, Kennedy, Gwen, Bell, Jimmy D., Thomas, E. Louise, Frost, Gary, Eriksen, Rebeca, Koivula, Robert W., Brage, Soren, Kaye, Jane, Hattersley, Andrew T., Heggie, Alison, McEvoy, Donna, 't Hart, Leen M., Beulens, Joline W., Elders, Petra, Musholt, Petra B., Ridderstrale, Martin, Hansen, Tue H., Allin, Kristine H., Hansen, Torben, Vestergaard, Henrik, Lundgaard, Agnete T., Thomsen, Henrik S., De Masi, Federico, Tsirigos, Konstantinos D., Brunak, Soren, Vinuela, Ana, Mahajan, Anubha, McDonald, Timothy J., Kokkola, Tarja, Forgie, Ian M., Giordano, Giuseppe N., Pavo, Imre, Ruetten, Hartmut, Dermitzakis, Emmanouil, McCarthy, Mark I., Pedersen, Oluf, Schwenk, Jochen M., Adamski, Jerzy, Franks, Paul W., Walker, Mark, Pearson, Ewan R., Mari, Andrea

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Genome-Wide Association Analysis of Pancreatic Beta-Cell Glucose Sensitivity von Deshmukh, Harshal A, Madsen, Anne Lundager, Viñuela, Ana, Have, Christian Theil, Grarup, Niels, Tura, Andrea, Mahajan, Anubha, Heggie, Alison J, Koivula, Robert W, De Masi, Federico, Tsirigos, Konstantinos K, Linneberg, Allan, Drivsholm, Thomas, Pedersen, Oluf, Sørensen, Thorkild I A, Astrup, Arne, Gjesing, Anette A P, Pavo, Imre, Wood, Andrew R, Ruetten, Hartmut, Jones, Angus G, Koopman, Anitra D M, Cederberg, Henna, Rutters, Femke, Ridderstrale, Martin, Laakso, Markku, McCarthy, Mark I, Frayling, Tim M, Ferrannini, Ele, Franks, Paul W, Pearson, Ewan R, Mari, Andrea, Hansen, Torben, Walker, Mark

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Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: descriptive characteristics of the epidemiological studies within the IMI DIRECT... von Koivula, Robert W., Forgie, Ian M., Kurbasic, Azra, Viñuela, Ana, Heggie, Alison, Giordano, Giuseppe N., Hansen, Tue H., Hudson, Michelle, Koopman, Anitra D. M., Rutters, Femke, Siloaho, Maritta, Allin, Kristine H., Brage, Søren, Brorsson, Caroline A., Dawed, Adem Y., De Masi, Federico, Groves, Christopher J., Kokkola, Tarja, Mahajan, Anubha, Perry, Mandy H., Rauh, Simone P., Ridderstråle, Martin, Teare, Harriet J. A., Thomas, E. Louise, Tura, Andrea, Vestergaard, Henrik, White, Tom, Adamski, Jerzy, Bell, Jimmy D., Beulens, Joline W., Brunak, Søren, Dermitzakis, Emmanouil T., Froguel, Philippe, Frost, Gary, Gupta, Ramneek, Hansen, Torben, Hattersley, Andrew, Jablonka, Bernd, Kaye, Jane, Laakso, Markku, McDonald, Timothy J., Pedersen, Oluf, Schwenk, Jochen M., Pavo, Imre, Mari, Andrea, McCarthy, Mark I., Ruetten, Hartmut, Walker, Mark, Pearson, Ewan, Franks, Paul W.

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A genome-wide association search for type 2 diabetes genes in African Americans von Palmer, Nicholette D, McDonough, Caitrin W, Hicks, Pamela J, Roh, Bong H, Wing, Maria R, An, S Sandy, Hester, Jessica M, Cooke, Jessica N, Bostrom, Meredith A, Rudock, Megan E, Talbert, Matthew E, Lewis, Joshua P, Ferrara, Assiamira, Lu, Lingyi, Ziegler, Julie T, Sale, Michele M, Divers, Jasmin, Shriner, Daniel, Adeyemo, Adebowale, Rotimi, Charles N, Ng, Maggie C Y, Langefeld, Carl D, Freedman, Barry I, Bowden, Donald W, Voight, Benjamin F, Scott, Laura J, Steinthorsdottir, Valgerdur, Morris, Andrew P, Dina, Christian, Welch, Ryan P, Zeggini, Eleftheria, Huth, Cornelia, Aulchenko, Yurii S, Thorleifsson, Gudmar, McCulloch, Laura J, Ferreira, Teresa, Grallert, Harald, Amin, Najaf, Wu, Guanming, Willer, Cristen J, Raychaudhuri, Soumya, McCarroll, Steve A, Langenberg, Claudia, Hofmann, Oliver M, Dupuis, Josée, Qi, Lu, Segrè, Ayellet V, van Hoek, Mandy, Navarro, Pau, Ardlie, Kristin, Balkau, Beverley, Benediktsson, Rafn, Bennett, Amanda J, Blagieva, Roza, Boerwinkle, Eric, Bonnycastle, Lori L, Boström, Kristina Bengtsson, Bravenboer, Bert, Bumpstead, Suzannah, Burtt, Noël P, Charpentier, Guillaume, Chines, Peter S, Cornelis, Marilyn, Couper, David J, Crawford, Gabe, Doney, Alex S F, Elliott, Katherine S, Elliott, Amanda L, Erdos, Michael R, Fox, Caroline S, Franklin, Christopher S, Ganser, Martha, Gieger, Christian, Grarup, Niels, Green, Todd, Griffin, Simon, Groves, Christopher J, Guiducci, Candace, Hadjadj, Samy, Hassanali, Neelam, Herder, Christian, Isomaa, Bo, Jackson, Anne U, Johnson, Paul R V, Jørgensen, Torben, Kao, Wen H L, Klopp, Norman, Kong, Augustine, Kraft, Peter, Kuusisto, Johanna, Lauritzen, Torsten, Li, Man, Lieverse, Aloysius, Lindgren, Cecilia M, Lyssenko, Valeriya, Marre, Michel, Meitinger, Thomas, Midthjell, Kristian, Morken, Mario A, Narisu, Narisu

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The role of physical activity in metabolic homeostasis before and after the onset of type 2 diabetes: an IMI DIRECT study von Koivula, Robert W., Atabaki-Pasdar, Naeimeh, Giordano, Giuseppe N., White, Tom, Adamski, Jerzy, Bell, Jimmy D., Beulens, Joline, Brage, Søren, Brunak, Søren, De Masi, Federico, Dermitzakis, Emmanouil T., Forgie, Ian M., Frost, Gary, Hansen, Torben, Hansen, Tue H., Hattersley, Andrew, Kokkola, Tarja, Kurbasic, Azra, Laakso, Markku, Mari, Andrea, McDonald, Timothy J., Pedersen, Oluf, Rutters, Femke, Schwenk, Jochen M., Teare, Harriet J. A., Thomas, E. Louise, Vinuela, Ana, Mahajan, Anubha, McCarthy, Mark I., Ruetten, Hartmut, Walker, Mark, Pearson, Ewan, Pavo, Imre, Franks, Paul W.

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Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes von Perry, John R.B., Weedon, Michael N., Langenberg, Claudia, Jackson, Anne U., Lyssenko, Valeriya, Sparsø, Thomas, Thorleifsson, Gudmar, Grallert, Harald, Ferrucci, Luigi, Maggio, Marcello, Paolisso, Giuseppe, Walker, Mark, Palmer, Colin N.A., Payne, Felicity, Young, Elizabeth, Herder, Christian, Narisu, Narisu, Morken, Mario A., Bonnycastle, Lori L., Owen, Katharine R., Shields, Beverley, Knight, Beatrice, Bennett, Amanda, Groves, Christopher J., Ruokonen, Aimo, Jarvelin, Marjo Riitta, Pearson, Ewan, Pascoe, Laura, Ferrannini, Ele, Bornstein, Stefan R., Stringham, Heather M., Scott, Laura J., Kuusisto, Johanna, Nilsson, Peter, Neptin, Malin, Gjesing, Anette P., Pisinger, Charlotta, Lauritzen, Torsten, Sandbaek, Annelli, Sampson, Mike, Zeggini, MAGIC, Ele, Lindgren, Cecilia M., Steinthorsdottir, Valgerdur, Thorsteinsdottir, Unnur, Hansen, Torben, Schwarz, Peter, Illig, Thomas, Laakso, Markku, Stefansson, Kari, Morris, Andrew D., Groop, Leif, Pedersen, Oluf, Boehnke, Michael, Barroso, Inês, Wareham, Nicholas J., Hattersley, Andrew T., McCarthy, Mark I., Frayling, Timothy M.

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The role of physical activity in metabolic homeostasis before and after the onset of type 2 diabetes: an IMI DIRECT study (vol 63, pg 744, 2020) von Koivula, Robert W., Atabaki-Pasdar, Naeimeh, Giordano, Giuseppe N., White, Tom, Adamski, Jerzy, Bell, Jimmy D., Beulens, Joline, Brage, Soren, Brunak, Soren, De Masi, Federico, Dermitzakis, Emmanouil T., Forgie, Ian M., Frost, Gary, Hansen, Torben, Hansen, Tue H., Hattersley, Andrew, Kokkola, Tarja, Kurbasic, Azra, Laakso, Markku, Mari, Andrea, McDonald, Timothy J., Pedersen, Oluf, Rutters, Femke, Schwenk, Jochen M., Teare, Harriet J. A., Thomas, E. Louise, Vinuela, Ana, Mahajan, Anubha, McCarthy, Mark I., Ruetten, Hartmut, Walker, Mark, Pearson, Ewan, Pavo, Imre, Franks, Paul W.

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Genome-Wide Association Analysis of Pancreatic Beta-Cell Glucose Sensitivity von Deshmukh, Harshal A., Madsen, Anne Lundager, Vinuela, Ana, Have, Christian Theil, Grarup, Niels, Tura, Andrea, Mahajan, Anubha, Heggie, Alison J., Koivula, Robert W., De Masi, Federico, Tsirigos, Konstantinos K., Linneberg, Allan, Drivsholm, Thomas, Pedersen, Oluf, Sorensen, Thorkild I. A., Astrup, Arne, Gjesing, Anette A. P., Pavo, Imre, Wood, Andrew R., Ruetten, Hartmut, Jones, Angus G., Koopman, Anitra D. M., Cederberg, Henna, Rutters, Femke, Ridderstrale, Martin, Laakso, Markku, McCarthy, Mark, Frayling, Tim M., Ferrannini, Ele, Franks, Paul W., Pearson, Ewan R., Mari, Andrea, Hansen, Torben, Walker, Mark

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Correction to: The role of physical activity in metabolic homeostasis before and after the onset of type 2 diabetes: an IMI DIRECT study von Koivula, Robert W., Atabaki-Pasdar, Naeimeh, Giordano, Giuseppe N., White, Tom, Adamski, Jerzy, Bell, Jimmy D., Beulens, Joline, Brage, Søren, Brunak, Søren, De Masi, Federico, Dermitzakis, Emmanouil T., Forgie, Ian M., Frost, Gary, Hansen, Torben, Hansen, Tue H., Hattersley, Andrew, Kokkola, Tarja, Kurbasic, Azra, Laakso, Markku, Mari, Andrea, McDonald, Timothy J., Pedersen, Oluf, Rutters, Femke, Schwenk, Jochen M., Teare, Harriet J. A., Thomas, E. Louise, Vinuela, Ana, Mahajan, Anubha, McCarthy, Mark I., Ruetten, Hartmut, Walker, Mark, Pearson, Ewan, Pavo, Imre, Franks, Paul W.

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Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: rationale and design of the epidemiological studies within the IMI DIRECT Consort... von Koivula, Robert W., Heggie, Alison, Barnett, Anna, Cederberg, Henna, Hansen, Tue H., Koopman, Anitra D., Ridderstråle, Martin, Rutters, Femke, Vestergaard, Henrik, Gupta, Ramneek, Herrgård, Sanna, Heymans, Martijn W., Perry, Mandy H., Rauh, Simone, Siloaho, Maritta, Teare, Harriet J. A., Thorand, Barbara, Bell, Jimmy, Brunak, Søren, Frost, Gary, Jablonka, Bernd, Mari, Andrea, McDonald, Tim J., Dekker, Jacqueline M., Hansen, Torben, Hattersley, Andrew, Laakso, Markku, Pedersen, Oluf, Koivisto, Veikko, Ruetten, Hartmut, Walker, Mark, Pearson, Ewan, Franks, Paul W.

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Low-Frequency Variants in HMGA1 Are Not Associated With Type 2 Diabetes Risk von MARQUEZ, Marcel, HUYVAERT, Marlene, PATTOU, Francois, POULAIN-GODEFROY, Odile, CHARPENTIER, Guillaume, CARLSSON, Lena M. S, JACOBSON, Peter, SJÖSTRÖM, Lars, LANTIERI, Olivier, HEUDE, Barbara, WALLEY, Andrew, BALKAU, Beverley, PERRY, John R. B, MARRE, Michel, FROGUEL, Philippe, CAUCHI, Stephane, PEARSON, Richard D, FALCHI, Mario, MORRIS, Andrew P, VIVEQUIN, Sidonie, LOBBENS, Stephane, YENGO, Loic, GAGET, Stefan

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Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: rationale and design of the epidemiological studies within the IMI DIRECT Consort... von Koivula, Robert W, Heggie, Alison, Barnett, Anna, Cederberg, Henna, Hansen, Tue H, Koopman, Anitra D, Ridderstråle, Martin, Rutters, Femke, Vestergaard, Henrik, Gupta, Ramneek, Herrgård, Sanna, Heymans, Martijn W, Perry, Mandy H, Rauh, Simone, Siloaho, Maritta, Teare, Harriet J. A, Thorand, Barbara, Bell, Jimmy, Brunak, Søren, Frost, Gary, Jablonka, Bernd, Mari, Andrea, McDonald, Tim J, Dekker, Jacqueline M, Hansen, Torben, Hattersley, Andrew, Laakso, Markku, Pedersen, Oluf, Koivisto, Veikko, Ruetten, Hartmut, Walker, Mark, Pearson, Ewan, Franks, Paul W

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