Natural regulatory mutations elevate the fetal globin gene via disruption of BCL11A or ZBTB7A binding von Martyn, Gabriella E., Wienert, Beeke, Yang, Lu, Shah, Manan, Norton, Laura J., Burdach, Jon, Kurita, Ryo, Nakamura, Yukio, Pearson, Richard C. M., Funnell, Alister P. W., Quinlan, Kate G. R., Crossley, Merlin

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KLF3 Regulates Muscle-Specific Gene Expression and Synergizes with Serum Response Factor on KLF Binding Sites von Himeda, Charis L., Ranish, Jeffrey A., Pearson, Richard C. M., Crossley, Merlin, Hauschka, Stephen D.

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Phosphorylation of Krüppel-like Factor 3 (KLF3/BKLF) and C-terminal Binding Protein 2 (CtBP2) by Homeodomain-interacting Protein Kinase 2 (HIPK2) Modulates KLF3 DNA Binding and Act... von Dewi, Vitri, Kwok, Alister, Lee, Stella, Lee, Ming Min, Tan, Yee Mun, Nicholas, Hannah R., Isono, Kyo-ichi, Wienert, Beeke, Mak, Ka Sin, Knights, Alexander J., Quinlan, Kate G.R., Cordwell, Stuart J., Funnell, Alister P.W., Pearson, Richard C.M., Crossley, Merlin

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Targeted Disruption of the Basic Krüppel-Like Factor Gene (Klf3) Reveals a Role in Adipogenesis von Sue, Nancy, Jack, Briony H. A., Eaton, Sally A., Pearson, Richard C. M., Funnell, Alister P. W., Turner, Jeremy, Czolij, Robert, Denyer, Gareth, Bao, Shisan, Molero-Navajas, Juan Carlos, Perkins, Andrew, Fujiwara, Yuko, Orkin, Stuart H., Bell-Anderson, Kim, Crossley, Merlin

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Loss of Krüppel-Like Factor 3 (KLF3/BKLF) Leads to Upregulation of the Insulin-Sensitizing Factor Adipolin (FAM132A/CTRP12/Clqdc2) von BELL-ANDERSON, Kim S, FUNNELL, Alister P, NICHOLAS, Hannah R, SAINSBURY, Amanda, TURNER, Nigel, PEARSON, Richard C, CROSSLEY, Merlin, WILLIAMS, Helen, HANAPI MAT JUSOH, SCULLY, Tiffany, LIM, Wooi F, BURDACH, Jon G, KA SIN MAK, KNIGHTS, Alexander J, HOY, Andrew J

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The mammalian zinc finger transcription factor Krüppel‐like factor 3 (KLF3/BKLF) von Pearson, Richard C.M., Funnell, Alister P.W., Crossley, Merlin

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Directing an artificial zinc finger protein to new targets by fusion to a non-DNA-binding domain von Lim, Wooi F, Burdach, Jon, Funnell, Alister P W, Pearson, Richard C M, Quinlan, Kate G R, Crossley, Merlin

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Generation of Mice Deficient in both KLF3/BKLF and KLF8 Reveals a Genetic Interaction and a Role for These Factors in Embryonic Globin Gene Silencing von Funnell, Alister P W, Mak, Ka Sin, Twine, Natalie A, Pelka, Gregory J, Norton, Laura J, Radziewic, Tania, Power, Melinda, Wilkins, Marc R, Bell-Anderson, Kim S, Fraser, Stuart T, Perkins, Andrew C, Tam, Patrick P, Pearson, Richard C M, Crossley, Merlin

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KLF1 directly activates expression of the novel fetal globin repressor ZBTB7A/LRF in erythroid cells von Norton, Laura J., Funnell, Alister P.W., Burdach, Jon, Wienert, Beeke, Kurita, Ryo, Nakamura, Yukio, Philipsen, Sjaak, Pearson, Richard C.M., Quinlan, Kate G.R., Crossley, Merlin

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The CACCC-Binding Protein KLF3/BKLF Represses a Subset of KLF1/EKLF Target Genes and Is Required for Proper Erythroid Maturation In Vivo von Funnell, Alister P. W., Norton, Laura J., Mak, Ka Sin, Burdach, Jon, Artuz, Crisbel M., Twine, Natalie A., Wilkins, Marc R., Power, Carl A., Hung, Tzong-Tyng, Perdomo, José, Koh, Philip, Bell-Anderson, Kim S., Orkin, Stuart H., Fraser, Stuart T., Perkins, Andrew C., Pearson, Richard C. M., Crossley, Merlin

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Direct competition between DNA binding factors highlights the role of Krüppel-like Factor 1 in the erythroid/megakaryocyte switch von Norton, Laura J., Hallal, Samantha, Stout, Elizabeth S., Funnell, Alister P. W., Pearson, Richard C. M., Crossley, Merlin, Quinlan, Kate G. R.

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A CpG Mutational Hotspot in a ONECUT Binding Site Accounts for the Prevalent Variant of Hemophilia B Leyden von Funnell, Alister P.W., Wilson, Michael D., Ballester, Benoit, Mak, Ka Sin, Burdach, Jon, Magan, Natisha, Pearson, Richard C.M., Lemaigre, Frederic P., Stowell, Kathryn M., Odom, Duncan T., Flicek, Paul, Crossley, Merlin

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Editing the genome to introduce a beneficial naturally occurring mutation associated with increased fetal globin von Wienert, Beeke, Funnell, Alister P. W., Norton, Laura J., Pearson, Richard C. M., Wilkinson-White, Lorna E., Lester, Krystal, Vadolas, Jim, Porteus, Matthew H., Matthews, Jacqueline M., Quinlan, Kate G. R., Crossley, Merlin

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Impaired B cell development in the absence of Krüppel-like factor 3 von Vu, Thi Thanh, Gatto, Dominique, Turner, Vivian, Funnell, Alister P W, Mak, Ka Sin, Norton, Laura J, Kaplan, Warren, Cowley, Mark J, Agenès, Fabien, Kirberg, Jörg, Brink, Robert, Pearson, Richard C M, Crossley, Merlin

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PU.1 and Haematopoietic Cell Fate: Dosage Matters von Mak, Ka Sin, Funnell, Alister P. W., Pearson, Richard C. M., Crossley, Merlin

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Network of Krüppel-like Factors (Klfs): Klf8 IS REPRESSED BY Klf3 AND ACTIVATED BY Klf1 IN VIVO von Eaton, Sally A, Funnell, Alister P.W, Sue, Nancy, Nicholas, Hannah, Pearson, Richard C.M, Crossley, Merlin

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Differential regulation of the α-globin locus by Krüppel-like Factor 3 in erythroid and non-erythroid cells von Funnell, Alister P W, Vernimmen, Douglas, Lim, Wooi F, Mak, Ka Sin, Wienert, Beeke, Martyn, Gabriella E, Artuz, Crisbel M, Burdach, Jon, Quinlan, Kate G R, Higgs, Douglas R, Whitelaw, Emma, Pearson, Richard C M, Crossley, Merlin

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Repression of chimeric transcripts emanating from endogenous retrotransposons by a sequence-specific transcription factor von Mak, Ka Sin, Burdach, Jon, Norton, Laura J, Pearson, Richard CM, Crossley, Merlin, Funnell, Alister PW

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Krüppel-like Factor 3 (KLF3/BKLF) Is Required for Widespread Repression of the Inflammatory Modulator Galectin-3 (Lgals3) von Knights, Alexander J., Yik, Jinfen J., Mat Jusoh, Hanapi, Norton, Laura J., Funnell, Alister P.W., Pearson, Richard C.M., Bell-Anderson, Kim S., Crossley, Merlin, Quinlan, Kate G.R.

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Regions outside the DNA-binding domain are critical for proper in vivo specificity of an archetypal zinc finger transcription factor von Burdach, Jon, Funnell, Alister P W, Mak, Ka Sin, Artuz, Crisbel M, Wienert, Beeke, Lim, Wooi F, Tan, Lit Yeen, Pearson, Richard C M, Crossley, Merlin

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