Discovery of Nonpungent Transient Receptor Potential Vanilloid 1 (TRPV1) Agonist as Strong Topical Analgesic von Ann, Jihyae, Kim, Ho Shin, Thorat, Shivaji A, Kim, Hee, Ha, Hee-Jin, Choi, Kwanghyun, Kim, Young-Ho, Kim, Minseok, Hwang, Sun Wook, Pearce, Larry V, Esch, Timothy E, Turcios, Noe A, Blumberg, Peter M, Lee, Jeewoo

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Discovery of Benzopyridone-Based Transient Receptor Potential Vanilloid 1 Agonists and Antagonists and the Structural Elucidation of Their Activity Shift von Thorat, Shivaji A., Lee, Yoonji, Jung, Aeran, Ann, Jihyae, Ahn, Songyeon, Baek, Jisoo, Zuo, Dongxu, Do, Nayeon, Jeong, Jin Ju, Blumberg, Peter M., Esch, Timothy E., Turcios, Noe A., Pearce, Larry, Ha, Hee-Jin, Yoo, Young Dong, Hong, Sunhye, Choi, Sun, Lee, Jeewoo

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Design, Synthesis, and Characterization of Novel sn-1 Heterocyclic DAG-Lactones as PKC Activators von Elhalem, Eleonora, Bellomo, Ana, Cooke, Mariana, Scravaglieri, Antonella, Pearce, Larry V, Peach, Megan L, Gandolfi Donadío, Lucía, Kazanietz, Marcelo G, Comin, María J

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Structural Insight into Tetrameric hTRPV1 from Homology Modeling, Molecular Docking, Molecular Dynamics Simulation, Virtual Screening, and Bioassay Validations von Feng, Zhiwei, Pearce, Larry V, Xu, Xiaomeng, Yang, Xiaole, Yang, Peng, Blumberg, Peter M, Xie, Xiang-Qun

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Engineering vanilloid-sensitivity into the rat TRPV2 channel von Zhang, Feng, Hanson, Sonya M, Jara-Oseguera, Andres, Krepkiy, Dmitriy, Bae, Chanhyung, Pearce, Larry V, Blumberg, Peter M, Newstead, Simon, Swartz, Kenton J

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Discovery of dual-acting opioid ligand and TRPV1 antagonists as novel therapeutic agents for pain von Lee, Hobin, Ahn, Songyeon, Ann, Jihyae, Ha, Heejin, Yoo, Young Dong, Kim, Young Ho, Hwang, Ji-Young, Hur, Kwang-Hyun, Jang, Choon-Gon, Pearce, Larry V., Esch, Timothy E., Lewin, Nancy E., Blumberg, Peter M., Lee, Jeewoo

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Combination of a Rapidly Penetrating Agonist and a Slowly Penetrating Antagonist Affords Agonist Action of Limited Duration at the Cellular Level von Pearce, Larry V, Ann, Jihyae, Blumberg, Peter M, Lee, Jeewoo

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Molecular Determinants of Vanilloid Sensitivity in TRPV1 von Gavva, Narender R, Klionsky, Lana, Qu, Yusheng, Shi, Licheng, Tamir, Rami, Edenson, Steve, Zhang, T J, Viswanadhan, Vellarkad N, Toth, Attila, Pearce, Larry V, Vanderah, Todd W, Porreca, Frank, Blumberg, Peter M, Lile, Jack, Sun, Yax, Wild, Ken, Louis, Jean-Claude, Treanor, James J S

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Novel Radiolabeled Vanilloid with Enhanced Specificity for Human Transient Receptor Potential Vanilloid 1 (TRPV1) von Pearce, Larry V, Ann, Jihyae, Jung, Aeran, Thorat, Shivaji A, Herold, Brienna K. A, Habtemichael, Amelework D, Blumberg, Peter M, Lee, Jeewoo

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2‑(3-Fluoro-4-methylsulfonylaminophenyl)propanamides as Potent Transient Receptor Potential Vanilloid 1 (TRPV1) Antagonists: Structure–Activity Relationships of 2‑Amino Derivatives... von Kim, Myeong Seop, Ryu, HyungChul, Kang, Dong Wook, Cho, Seong-Hee, Seo, Sejin, Park, Young Soo, Kim, Mi-Yeon, Kwak, Eun Joo, Kim, Yong Soo, Bhondwe, Rahul S, Kim, Ho Shin, Park, Seul-gi, Son, Karam, Choi, Sun, DeAndrea-Lazarus, Ian A, Pearce, Larry V, Blumberg, Peter M, Frank, Robert, Bahrenberg, Gregor, Stockhausen, Hannelore, Kögel, Babette Y, Schiene, Klaus, Christoph, Thomas, Lee, Jeewoo

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Structural insights into transient receptor potential vanilloid type 1 (TRPV1) from homology modeling, flexible docking, and mutational studies von Lee, Jin Hee, Lee, Yoonji, Ryu, HyungChul, Kang, Dong Wook, Lee, Jeewoo, Lazar, Jozsef, Pearce, Larry V., Pavlyukovets, Vladimir A., Blumberg, Peter M., Choi, Sun

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Multi-Functional Diarylurea Small Molecule Inhibitors of TRPV1 with Therapeutic Potential for Neuroinflammation von Feng, Zhiwei, Pearce, Larry V., Zhang, Yu, Xing, Changrui, Herold, Brienna K. A., Ma, Shifan, Hu, Ziheng, Turcios, Noe A., Yang, Peng, Tong, Qin, McCall, Anna K., Blumberg, Peter M., Xie, Xiang-Qun

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Asymmetric synthesis and receptor activity of chiral simplified resiniferatoxin (sRTX) analogues as transient receptor potential vanilloid 1 (TRPV1) ligands von Kim, Myeong Seop, Ki, Yooran, Ahn, Song Yeon, Yoon, Suyoung, Kim, Sung-Eun, Park, Hyeung-Geun, Sun, Wei, Son, Karam, Cui, Minghua, Choi, Sun, Pearce, Larry V, Esch, Timothy E, Deandrea-Lazarus, Ian A, Blumberg, Peter M, Lee, Jeewoo

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Discovery of N-(3-fluoro-4-methylsulfonamidomethylphenyl)urea as a potent TRPV1 antagonistic template von Ann, Jihyae, Sun, Wei, Zhou, Xing, Jung, Aeran, Baek, Jisoo, Lee, Sunho, Kim, Changhoon, Yoon, Suyoung, Hong, Sunhye, Choi, Sun, Turcios, Noe A., Herold, Brienna K.A., Esch, Timothy E., Lewin, Nancy E., Abramovitz, Adelle, Pearce, Larry V., Blumberg, Peter M., Lee, Jeewoo

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2-Sulfonamidopyridine C-region analogs of 2-(3-fluoro-4-methylsulfonamidophenyl)propanamides as potent TRPV1 antagonists von Ann, Jihyae, Ki, Yooran, Yoon, Suyoung, Kim, Myeong Seop, Lee, Jung-Un, Kim, Changhoon, Lee, Sunho, Jung, Aeran, Baek, Jisoo, Hong, Sunhye, Choi, Sun, Pearce, Larry V., Esch, Timothy E., Turcios, Noe A., Lewin, Nancy E., Ogunjirin, Adebowale E., Herold, Brienna K.A., McCall, Anna K., Blumberg, Peter M., Lee, Jeewoo

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Synthesis and biological evaluation of [11 C]SB366791: A new PET-radioligand for in vivo imaging of the TRPV1 receptor von van Veghel, Daisy, Cleynhens, Jan, Pearce, Larry V, Blumberg, Peter M, Van Laere, Koen, Verbruggen, Alfons, Bormans, Guy

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α-Methylated simplified resiniferatoxin (sRTX) thiourea analogues as potent and stereospecific TRPV1 antagonists von Kim, Ho Shin, Jin, Mi-Kyoung, Kang, Sang-Uk, Lim, Ju-Ok, Tran, Phuong-Thao, Hoang, Van-Hai, Ann, Jihyae, Ha, Tae-Hwan, Pearce, Larry V., Pavlyukovets, Vladimir A., Blumberg, Peter M., Lee, Jeewoo

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N-(3-Acyloxy-2-benzylpropyl)-N‘-[4-(methylsulfonylamino)benzyl]thiourea Analogues:  Novel Potent and High Affinity Antagonists and Partial Antagonists of the Vanilloid Receptor von Lee, Jeewoo, Lee, Jiyoun, Kang, Myungshim, Shin, Myoungyoup, Kim, Ji-Min, Kang, Sang-Uk, Lim, Ju-Ok, Choi, Hyun-Kyung, Suh, Young-Ger, Park, Hyeung-Geun, Oh, Uhtaek, Kim, Hee-Doo, Park, Young-Ho, Ha, Hee-Jin, Kim, Young-Ho, Toth, Attila, Wang, Yun, Tran, Richard, Pearce, Larry V, Lundberg, Daniel J, Blumberg, Peter M

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Evodiamine functions as an agonist for the vanilloid receptor TRPV1 von Pearce, Larry V, Petukhov, Pavel A, Szabo, Tamas, Kedei, Noemi, Bizik, Fero, Kozikowski, Alan P, Blumberg, Peter M

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The carbonate analogues of 5′-halogenated resiniferatoxin as TRPV1 ligands von Lim, Kwang Su, Lee, Hobin, Kim, Sung Eun, Ha, Tae-Hwan, Ann, Jihyae, Son, Karam, Choi, Sun, Sun, Wei, Pearce, Larry V., DeAndrea-Lazarus, Ian A., Blumberg, Peter M., Lee, Jeewoo

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