Mechanisms of Apoptosis Resistance to NK Cell-Mediated Cytotoxicity in Cancer von Sordo-Bahamonde, Christian, Lorenzo-Herrero, Seila, Payer, Angel R., Gonzalez, Segundo, Lopez-Soto, Alejandro

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BTLA/HVEM Axis Induces NK Cell Immunosuppression and Poor Outcome in Chronic Lymphocytic Leukemia von Sordo-Bahamonde, Christian, Lorenzo-Herrero, Seila, Gonzalez-Rodriguez, Ana P., R. Payer, Angel, Gonzalez-Garcia, Esther, Lopez-Soto, Alejandro, Gonzalez, Segundo

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LAG-3 Blockade with Relatlimab (BMS-986016) Restores Anti-Leukemic Responses in Chronic Lymphocytic Leukemia von Sordo-Bahamonde, Christian, Lorenzo-Herrero, Seila, Gonzalez-Rodriguez, Ana P., Payer, Angel R., Gonzalez-Garcia, Esther, Lopez-Soto, Alejandro, Gonzalez, Segundo

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BTLA dysregulation correlates with poor outcome and diminished T cell-mediated antitumor responses in chronic lymphocytic leukemia von Sordo-Bahamonde, Christian, Lorenzo-Herrero, Seila, Martínez-Pérez, Alejandra, Gonzalez-Rodriguez, Ana P., Payer, Ángel R., González-García, Esther, Aguilar-García, Candelaria, González-Rodríguez, Sara, López-Soto, Alejandro, García-Torre, Alejandra, Gonzalez, Segundo

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Expansion of NK cells and reduction of NKG2D expression in chronic lymphocytic leukemia. Correlation with progressive disease von Huergo-Zapico, Leticia, Acebes-Huerta, Andrea, Gonzalez-Rodriguez, Ana Pilar, Contesti, Juan, Gonzalez-García, Esther, Payer, Angel R, Villa-Alvarez, Monica, Fernández-Guizán, Azahara, López-Soto, Alejandro, Gonzalez, Segundo

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Mutations in the RAS-BRAF-MAPK-ERK pathway define a specific subgroup of patients with adverse clinical features and provide new therapeutic options in chronic lymphocytic leukemia von Giménez, Neus, Martínez-Trillos, Alejandra, Montraveta, Arnau, Lopez-Guerra, Mónica, Rosich, Laia, Nadeu, Ferran, Valero, Juan G, Aymerich, Marta, Magnano, Laura, Rozman, Maria, Matutes, Estella, Delgado, Julio, Baumann, Tycho, Gine, Eva, González, Marcos, Alcoceba, Miguel, Terol, M José, Navarro, Blanca, Colado, Enrique, Payer, Angel R, Puente, Xose S, López-Otín, Carlos, Lopez-Guillermo, Armando, Campo, Elias, Colomer, Dolors, Villamor, Neus

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Ig-Like Transcript 2 (ILT2) Blockade and Lenalidomide Restore NK Cell Function in Chronic Lymphocytic Leukemia von Villa-Álvarez, Mónica, Sordo-Bahamonde, Christian, Lorenzo-Herrero, Seila, Gonzalez-Rodriguez, Ana P, Payer, Angel R, Gonzalez-Garcia, Esther, Villa-Álvarez, María C, López-Soto, Alejandro, Gonzalez, Segundo

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The Mithralog EC-7072 Induces Chronic Lymphocytic Leukemia Cell Death by Targeting Tonic B-Cell Receptor Signaling von Lorenzo-Herrero, Seila, Sordo-Bahamonde, Christian, Bretones, Gabriel, Payer, Ángel R, González-Rodríguez, Ana P, González-García, Esther, Pérez-Escuredo, Jhudit, Villa-Álvarez, Mónica, Núñez, Luz-Elena, Morís, Francisco, Gonzalez, Segundo, López-Soto, Alejandro

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Genomic complexity and IGHV mutational status are key predictors of outcome of chronic lymphocytic leukemia patients with TP53 disruption von Delgado, Julio, Salaverria, Itziar, Baumann, Tycho, Martínez-Trillos, Alejandra, Lee, Eriong, Jiménez, Laura, Navarro, Alba, Royo, Cristina, Santacruz, Rodrigo, López, Cristina, Payer, Angel R, Colado, Enrique, González, Marcos, Armengol, Lluís, Colomer, Dolors, Pinyol, Magda, Villamor, Neus, Aymerich, Marta, Carrió, Ana, Costa, Dolors, Clot, Guillem, Giné, Eva, López-Guillermo, Armando, Campo, Elías, Beà, Sílvia

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IGLV3-21R110 mutation has prognostic value in patients with treatment-naive chronic lymphocytic leukemia von Syrykh, Charlotte, Pons-Brun, Berta, Russiñol, Núria, Playa-Albinyana, Heribert, Baumann, Tycho, Duran-Ferrer, Martí, Kulis, Marta, Carbó-Meix, Anna, Mozas, Pablo, Alcoceba, Miguel, González, Marcos, Navarro-Bailón, Almudena, Colado, Enrique, Payer, Ángel R., Aymerich, Marta, Terol, María J., Lu, Junyan, Knisbacher, Binyamin A., Hahn, Cynthia K., Ruiz-Gaspà, Sílvia, Enjuanes, Anna, Wu, Catherine J., Getz, Gad, Zenz, Thorsten, López-Guillermo, Armando, Martín-Subero, José I., Colomer, Dolors, Delgado, Julio, Campo, Elías, Nadeu, Ferran

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Zoledronic acid as compared with observation in multiple myeloma patients at biochemical relapse: results of the randomized AZABACHE Spanish trial von García-Sanz, Ramón, Oriol, Albert, Moreno, María J, de la Rubia, Javier, Payer, Angel R, Hernández, Miguel T, Palomera, Luis, Teruel, Ana I, Blanchard, María J, Gironella, Mercedes, Ribas, Paz, Bargay, Joan, Abellá, Eugenia, Granell, Miquel, Ocio, Enrique M, Ribera, Josep M, San Miguel, Jesús F, Mateos, María V

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Ig-like transcript 2 (ILT2) suppresses T cell function in chronic lymphocytic leukemia von Villa-Álvarez, Mónica, Lorenzo-Herrero, Seila, Gonzalez-Rodriguez, Ana P., López-Soto, Alejandro, Payer, Angel R., Gonzalez-Garcia, Esther, Huergo-Zapico, Leticia, Gonzalez, Segundo

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Mutations in TLR/MYD88 pathway identify a subset of young chronic lymphocytic leukemia patients with favorable outcome von Martínez-Trillos, Alejandra, Pinyol, Magda, Navarro, Alba, Aymerich, Marta, Jares, Pedro, Juan, Manel, Rozman, María, Colomer, Dolors, Delgado, Julio, Giné, Eva, González-Díaz, Marcos, Hernández-Rivas, Jesús M, Colado, Enrique, Rayón, Consolación, Payer, Angel R, Terol, Maria José, Navarro, Blanca, Quesada, Victor, Puente, Xosé S, Rozman, Ciril, López-Otín, Carlos, Campo, Elías, López-Guillermo, Armando, Villamor, Neus

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Non-coding recurrent mutations in chronic lymphocytic leukaemia von Puente, Xose S., Beà, Silvia, Valdés-Mas, Rafael, Villamor, Neus, Gutiérrez-Abril, Jesús, Martín-Subero, José I., Munar, Marta, Rubio-Pérez, Carlota, Jares, Pedro, Aymerich, Marta, Baumann, Tycho, Beekman, Renée, Belver, Laura, Carrio, Anna, Castellano, Giancarlo, Clot, Guillem, Colado, Enrique, Colomer, Dolors, Costa, Dolors, Delgado, Julio, Enjuanes, Anna, Estivill, Xavier, Ferrando, Adolfo A., Gelpí, Josep L., González, Blanca, González, Santiago, González, Marcos, Gut, Marta, Hernández-Rivas, Jesús M., López-Guerra, Mónica, Martín-García, David, Navarro, Alba, Nicolás, Pilar, Orozco, Modesto, Payer, Ángel R., Pinyol, Magda, Pisano, David G., Puente, Diana A., Queirós, Ana C., Quesada, Víctor, Romeo-Casabona, Carlos M., Royo, Cristina, Royo, Romina, Rozman, María, Russiñol, Nuria, Salaverría, Itziar, Stamatopoulos, Kostas, Stunnenberg, Hendrik G., Tamborero, David, Terol, María J., Valencia, Alfonso, López-Bigas, Nuria, Torrents, David, Gut, Ivo, López-Guillermo, Armando, López-Otín, Carlos, Campo, Elías

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Lenalidomide Induces Immunomodulation in Chronic Lymphocytic Leukemia and Enhances Antitumor Immune Responses Mediated by NK and CD4 T Cells von González, Segundo, Payer, Angel R., Fernandez-Guizan, Azahara, González-Rodríguez, Ana Pilar, Huergo-Zapico, Leticia, Acebes-Huerta, Andrea, López-Soto, Alejandro

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Driver Mutations and Single Copy Number Abnormalities Identify Binet Stage A Patients with Chronic Lymphocytic Leukemia with Aggressive Progression von Gonzalez-Rodriguez, Ana P., Payer, Angel R., Menendez-Suarez, Juan J., Sordo-Bahamonde, Christian, Lorenzo-Herrero, Seila, Zanabili, Joud, Fonseca, Ariana, Gonzalez-Huerta, Ana Julia, Palomo, Pilar, Gonzalez, Segundo

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Lenalidomide and Chronic Lymphocytic Leukemia von González, Segundo, Villa-Alvarez, Monica, Huergo-Zapico, Leticia, Acebes-Huerta, Andrea, Payer, Angel R., González-Rodríguez, Ana Pilar, Gonzalez-García, Esther

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Mutations in RAS-BRAF-MAPK-ERK pathway define a specific subgroup of patients with adverse clinical features and provide new therapeutic options in chronic lymphocytic leukemia von Giménez Carabaza, Neus, Martínez Trillos, Alejandra, Montraveta, Arnau, López-Guerra, Mónica, Rosich, Laia, Nadeu, Ferran, Valero, Juan G, Aymerich Gregorio, Marta, Magnano, Laura, Rozman, María, Matutes, Estella, Delgado, Julio (Delgado González), Baumann, Tycho, Gine, Eva, González, Marcos, Alcoceba, Miguel, Terol, Maria José, Navarro, Blanca, Colado, Enrique, Payer, Ángel R, Puente, Xose S, López-Otin, Carlos, López Guillermo, Armando, Campo Güerri, Elias, Colomer Pujol, Dolors, Villamor i Casas, Neus

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Mutations in the Toll-like receptor/MYD88 pathway in young (≤50 years) CLL patients von Martínez-Trillos, Alejandra, Pinyol, Magda, Navarro, Alba, Aymerich, Marta, Jares, Pedro, Juan, Manel, Rozman, María, Colomer, Dolors, Delgado, Julio, Gine, Eva, González-Díaz, Marcos, Hernández-Rivas, Jesús M, Colado, Enrique, Rayón, Consolación, Payer, Angel R, Terol, Maria José, Navarro, Blanca, Quesada, Victor, Puente, Xosé S, Rozman, Ciril, López-Otín, Carlos, Campo, Elías, López-Guillermo, Armando, PhD MD, Villamor, Neus

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Genomic complexity and IGHV mutational status are key predictors of outcome of chronic lymphocytic leukemia patients with TP53 disruption von Delgado, Julio (Delgado González), Salaverria Frigola, Itziar, Baumann, Tycho, Martínez Trillos, Alejandra, Lee, Eriong, Jiménez, Laura, Navarro López, Alba, Royo Moreno, Cristina, Santacruz, Rodrigo, López, Cristina, Payer, Ángel R, Colado, Enrique, González, Marcos, Armengol, Lluís, Colomer Pujol, Dolors, Pinyol, Magda, Villamor i Casas, Neus, Aymerich Gregorio, Marta, Carrió, Ana, Costa, Dolors, Clot, Guillem, Giné Soca, Eva, López Guillermo, Armando, Campo Güerri, Elias, Beà Bobet, Sílvia M

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