Design and synthesis of cyanamides as potent and selective N-acylethanolamine acid amidase inhibitors von Malamas, Michael S., Farah, Shrouq I., Lamani, Manjunath, Pelekoudas, Dimitrios N., Perry, Nicholas Thomas, Rajarshi, Girija, Miyabe, Christina Yume, Chandrashekhar, Honrao, West, Jay, Pavlopoulos, Spiro, Makriyannis, Alexandros

Volltext

Aliphatic Azides as Selective Cysteine Labeling Reagents for Integral Membrane Proteins von Szymanski, Dennis, Papanastasiou, Malvina, Pandarinathan, Lakshmipathi, Zvonok, Nikolai, Janero, David R, Pavlopoulos, Spiro, Vouros, Paul, Makriyannis, Alexandros

Volltext

K-Ras Populates Conformational States Differently from Its Isoform H-Ras and Oncogenic Mutant K-RasG12D von Parker, Jillian A., Volmar, Alicia Y., Pavlopoulos, Spiro, Mattos, Carla

Volltext

Mechanisms of isoform-specific residue influence on GTP-bound HRas, KRas, and NRas von Volmar, Alicia Y, Guterres, Hugo, Zhou, Hao, Reid, Derion, Pavlopoulos, Spiro, Makowski, Lee, Mattos, Carla

Volltext

Isoform-Specific Destabilization of the Active Site Reveals a Molecular Mechanism of Intrinsic Activation of KRas G13D von Johnson, Christian W., Lin, Yi-Jang, Reid, Derion, Parker, Jillian, Pavlopoulos, Spiro, Dischinger, Patrick, Graveel, Carrie, Aguirre, Andrew J., Steensma, Matthew, Haigis, Kevin M., Mattos, Carla

Volltext

Effects of Distal Mutations on the Structure, Dynamics and Catalysis of Human Monoacylglycerol Lipase von Tyukhtenko, Sergiy, Rajarshi, Girija, Karageorgos, Ioannis, Zvonok, Nikolai, Gallagher, Elyssia S., Huang, Hongwei, Vemuri, Kiran, Hudgens, Jeffrey W., Ma, Xiaoyu, Nasr, Mahmoud L., Pavlopoulos, Spiro, Makriyannis, Alexandros

Volltext

Specific Inter-residue Interactions as Determinants of Human Monoacylglycerol Lipase Catalytic Competency: A ROLE FOR GLOBAL CONFORMATIONAL CHANGES von Tyukhtenko, Sergiy, Karageorgos, Ioannis, Rajarshi, Girija, Zvonok, Nikolai, Pavlopoulos, Spiro, Janero, David R, Makriyannis, Alexandros

Volltext

Design and Structure–Activity Relationships of Isothiocyanates as Potent and Selective N‑Acylethanolamine-Hydrolyzing Acid Amidase Inhibitors von Malamas, Michael S, Pavlopoulos, Spiro, Alapafuja, Shakiru O, Farah, Shrouq I, Zvonok, Alexander, Mohammad, Khadijah A, West, Jay, Perry, Nicholas Thomas, Pelekoudas, Dimitrios N, Rajarshi, Girija, Shields, Christina, Chandrashekhar, Honrao, Wood, Jodi, Makriyannis, Alexandros

Volltext

Specific Inter-residue Interactions as Determinants of Human Monoacylglycerol Lipase Catalytic Competency von Tyukhtenko, Sergiy, Karageorgos, Ioannis, Rajarshi, Girija, Zvonok, Nikolai, Pavlopoulos, Spiro, Janero, David R., Makriyannis, Alexandros

Volltext

Secretion, isotopic labeling and deglycosylation of N-acylethanolamine acid amidase for biophysical studies von Pavlopoulos, Spiro, Pelekoudas, Dimitrios N., Benchama, Othman, Rawlins, Catherine M., Agar, Jeffrey N., West, Jay M., Malamas, Michael, Zvonok, Nikolai, Makriyannis, Alexandros

Volltext

Binding between a Distal C-Terminus Fragment of Cannabinoid Receptor 1 and Arrestin-2 von Singh, Shubhadra N, Bakshi, Kunal, Mercier, Richard W, Makriyannis, Alexandros, Pavlopoulos, Spiro

Volltext

The interaction of cannabinoid receptor agonists, CP55940 and WIN55212-2 with membranes using solid state 2H NMR von Tian, Xiaoyu, Pavlopoulos, Spiro, Yang, De-Ping, Makriyannis, Alexandros

Volltext

Interaction of a fragment of the cannabinoid CB1 receptor C-terminus with arrestin-2 von Bakshi, Kunal, Mercier, Richard W., Pavlopoulos, Spiro

Volltext

Magnetically Aligned Bicelles To Study the Orientation of Lipophilic Ligands in Membrane Bilayers von Guo, Jianxin, Yang, De-Ping, Chari, Ravi, Tian, Xiaoyu, Pavlopoulos, Spiro, Lu, Dai, Makriyannis, Alexandros

Volltext

Conformational Study of Lipophilic Ligands in Phospholipid Model Membrane Systems by Solution NMR von Guo, Jianxin, Pavlopoulos, Spiro, Tian, Xiaoyu, Lu, Dai, Nikas, Spyros P, Yang, De-Ping, Makriyannis, Alexandros

Volltext

Determination of Anandamide Amidase Activity Using Ultraviolet-Active Amine Derivatives and Reverse-Phase High-Performance Liquid Chromatography von Qin, Ce, Lin, Sonyuan, Lang, Wensheng, Goutopoulos, Andreas, Pavlopoulos, Spiro, Mauri, Frank, Makriyannis, Alexandros

Volltext

Structural Characterization of the 1:1 Adduct Formed between the Antitumor Antibiotic Hedamycin and the Oligonucleotide Duplex d(CACGTG)2 by 2D NMR Spectroscopy von Pavlopoulos, Spiro, Bicknell, Wendy, Craik, David J, Wickham, Geoffrey

Volltext

Effects of Distal Mutations on the Structure, Dynamics and Catalysis of Human Monoacylglycerol Lipase von Tyukhtenko, Sergiy, Rajarshi, Girija, Karageorgos, Ioannis, Zvonok, Nikolai, Gallagher, Elyssia S, Huang, Hongwei, Vemuri, Kiran, Hudgens, Jeffrey W, Ma, Xiaoyu, Nasr, Mahmoud L, Pavlopoulos, Spiro, Makriyannis, Alexandros

Volltext bestellen

Characterization of the sequential non-covalent and covalent interactions of the antitumour antibiotic hedamycin with double stranded DNA by NMR spectroscopy von Pavlopoulos, Spiro, Bicknell, Wendy, Wickham, Geoffrey, Craik, David J.

Volltext

Conformational Studies on a Diastereoisomeric Pair of Tricyclic Nonclassical Cannabinoids by NMR Spectroscopy and Computer Molecular Modeling von Xie, Xiang-Qun, Pavlopoulos, Spiro, DiMeglio, C. M, Makriyannis, Alexandros

Volltext