Atezolizumab with or without cobimetinib versus regorafenib in previously treated metastatic colorectal cancer (IMblaze370): a multicentre, open-label, phase 3, randomised, control... von Eng, Cathy, Kim, Tae Won, Bendell, Johanna, Argilés, Guillem, Tebbutt, Niall C, Di Bartolomeo, Maria, Falcone, Alfredo, Fakih, Marwan, Kozloff, Mark, Segal, Neil H, Sobrero, Alberto, Yan, Yibing, Chang, Ilsung, Uyei, Anne, Roberts, Louise, Ciardiello, Fortunato, Ahn, JB, Asselah, J, Badarinath, S, Baijal, S, Begbie, S, Berry, S, Canon, JL, Carbone, RG, Cervantes, A, Cha, YJ, Chang, K, Chaudhry, A, Chmielowska, E, Cho, SH, Chu, D, Couture, F, Cultrera, J, Cunningham, D, Van Cutsem, E, Cuyle, PJ, Davies, J, Dowden, S, Dvorkin, M, Ganju, V, Garcia, RV, Kerr, R, Kim, TY, King, K, Kortmansky, J, Kozloff, M, Lam, KO, Lee, J, Lee, AS, Lesperance, B, Luppi, G, Ma, B, Maiello, E, Mandanas, R, Marshall, J, Marx, G, Mullamitha, S, Nechaeva, M, Park, JO, Pavlakis, N, Ponce, CG, Potemski, P, Raouf, S, Reeves, J, Segal, N, Siena, S, Smolin, A, Streb, JO, Strickland, A, Szutowicz-Zielinska, E, Tabernero, JM, Tan, B, Valera, JS, Van den Eynde, M, Vergauwe, P, Vickers, M, Womack, M, Wroblewska, M, Young, R

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Patterns of Human Respiratory Viruses and Lack of MERS-Coronavirus in Patients with Acute Upper Respiratory Tract Infections in Southwestern Province of Saudi Arabia von Azhar, Esam, Ejeeli, Saleh, Alsubhi, Tagreed L., Hassan, Ahmed M., Badroon, Nassrin A., Alshrari, Ahmed S., Hashem, Anwar M., Basode, Vinod Kumar, Abdulhaq, Ahmed A., Solan, Yahiya

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Pembrolizumab in Microsatellite-Instability–High Advanced Colorectal Cancer von André, Thierry, Shiu, Kai-Keen, Kim, Tae Won, Jensen, Benny Vittrup, Jensen, Lars Henrik, Punt, Cornelis, Smith, Denis, Garcia-Carbonero, Rocio, Benavides, Manuel, Gibbs, Peter, de la Fouchardiere, Christelle, Rivera, Fernando, Elez, Elena, Bendell, Johanna, Le, Dung T, Yoshino, Takayuki, Van Cutsem, Eric, Yang, Ping, Farooqui, Mohammed Z.H, Marinello, Patricia, Diaz, Luis A

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Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer von Balachandran, Vinod P., Łuksza, Marta, Zhao, Julia N., Makarov, Vladimir, Moral, John Alec, Remark, Romain, Herbst, Brian, Askan, Gokce, Bhanot, Umesh, Senbabaoglu, Yasin, Wells, Daniel K., Cary, Charles Ian Ormsby, Grbovic-Huezo, Olivera, Attiyeh, Marc, Medina, Benjamin, Zhang, Jennifer, Loo, Jennifer, Saglimbeni, Joseph, Abu-Akeel, Mohsen, Zappasodi, Roberta, Riaz, Nadeem, Smoragiewicz, Martin, Kelley, Z. Larkin, Basturk, Olca, Gönen, Mithat, Levine, Arnold J., Allen, Peter J., Fearon, Douglas T., Merad, Miriam, Gnjatic, Sacha, Iacobuzio-Donahue, Christine A., Wolchok, Jedd D., DeMatteo, Ronald P., Chan, Timothy A., Greenbaum, Benjamin D., Merghoub, Taha, Leach, Steven D.

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Direct Detection and Identification of Enteroviruses from Faeces of Healthy Nigerian Children Using a Cell-Culture Independent RT-Seminested PCR Assay von Nudamajo, Felix Yasha, Coker, Bamidele Atinuke, Adewumi, Moses Olubusuyi, Faleye, Temitope Oluwasegun Cephas, Adeniji, Johnson Adekunle

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Arterial ischemic stroke risk factors: The international pediatric stroke study von Mackay, Mark T., Wiznitzer, Max, Benedict, Susan L., Lee, Katherine J., deVeber, Gabrielle A., Ganesan, Vijeya

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Genomic analyses identify molecular subtypes of pancreatic cancer von Bailey, Peter, Chang, David K., Nones, Katia, Johns, Amber L., Patch, Ann-Marie, Gingras, Marie-Claude, Miller, David K., Christ, Angelika N., Bruxner, Tim J. C., Quinn, Michael C., Nourse, Craig, Murtaugh, L. Charles, Harliwong, Ivon, Idrisoglu, Senel, Manning, Suzanne, Nourbakhsh, Ehsan, Wani, Shivangi, Fink, Lynn, Holmes, Oliver, Chin, Venessa, Anderson, Matthew J., Kazakoff, Stephen, Leonard, Conrad, Newell, Felicity, Waddell, Nick, Wood, Scott, Xu, Qinying, Wilson, Peter J., Cloonan, Nicole, Kassahn, Karin S., Taylor, Darrin, Quek, Kelly, Robertson, Alan, Pantano, Lorena, Mincarelli, Laura, Sanchez, Luis N., Evers, Lisa, Wu, Jianmin, Pinese, Mark, Cowley, Mark J., Jones, Marc D., Colvin, Emily K., Nagrial, Adnan M., Humphrey, Emily S., Chantrill, Lorraine A., Mawson, Amanda, Humphris, Jeremy, Chou, Angela, Pajic, Marina, Scarlett, Christopher J., Pinho, Andreia V., Giry-Laterriere, Marc, Rooman, Ilse, Samra, Jaswinder S., Kench, James G., Lovell, Jessica A., Merrett, Neil D., Toon, Christopher W., Epari, Krishna, Nguyen, Nam Q., Barbour, Andrew, Zeps, Nikolajs, Moran-Jones, Kim, Jamieson, Nigel B., Graham, Janet S., Duthie, Fraser, Oien, Karin, Hair, Jane, Grützmann, Robert, Maitra, Anirban, Iacobuzio-Donahue, Christine A., Wolfgang, Christopher L., Morgan, Richard A., Lawlor, Rita T., Corbo, Vincenzo, Bassi, Claudio, Rusev, Borislav, Capelli, Paola, Salvia, Roberto, Tortora, Giampaolo, Mukhopadhyay, Debabrata, Petersen, Gloria M., Munzy, Donna M., Fisher, William E., Karim, Saadia A., Eshleman, James R., Hruban, Ralph H., Pilarsky, Christian, Sansom, Owen J., Scarpa, Aldo, Bailey, Ulla-Maja Hagbo, Hofmann, Oliver, Sutherland, Robert L., Wheeler, David A., Gill, Anthony J., Gibbs, Richard A., Pearson, John V., Waddell, Nicola, Biankin, Andrew V., Grimmond, Sean M.

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Alectinib versus Crizotinib in Untreated ALK-Positive Non–Small-Cell Lung Cancer von Peters, Solange, Camidge, D. Ross, Shaw, Alice T, Gadgeel, Shirish, Ahn, Jin S, Kim, Dong-Wan, Ou, Sai-Hong I, Pérol, Maurice, Dziadziuszko, Rafal, Rosell, Rafael, Zeaiter, Ali, Mitry, Emmanuel, Golding, Sophie, Balas, Bogdana, Noe, Johannes, Morcos, Peter N, Mok, Tony

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Whole genomes redefine the mutational landscape of pancreatic cancer von Waddell, Nicola, Pajic, Marina, Patch, Ann-Marie, Chang, David K., Kassahn, Karin S., Bailey, Peter, Johns, Amber L., Miller, David, Nones, Katia, Quek, Kelly, Quinn, Michael C. J., Robertson, Alan J., Fadlullah, Muhammad Z. H., Bruxner, Tim J. C., Christ, Angelika N., Harliwong, Ivon, Idrisoglu, Senel, Manning, Suzanne, Nourse, Craig, Nourbakhsh, Ehsan, Wani, Shivangi, Wilson, Peter J., Markham, Emma, Cloonan, Nicole, Anderson, Matthew J., Fink, J. Lynn, Holmes, Oliver, Kazakoff, Stephen H., Leonard, Conrad, Newell, Felicity, Poudel, Barsha, Song, Sarah, Taylor, Darrin, Waddell, Nick, Wood, Scott, Xu, Qinying, Wu, Jianmin, Pinese, Mark, Cowley, Mark J., Lee, Hong C., Jones, Marc D., Nagrial, Adnan M., Humphris, Jeremy, Chantrill, Lorraine A., Chin, Venessa, Steinmann, Angela M., Mawson, Amanda, Humphrey, Emily S., Colvin, Emily K., Chou, Angela, Scarlett, Christopher J., Pinho, Andreia V., Giry-Laterriere, Marc, Rooman, Ilse, Samra, Jaswinder S., Kench, James G., Pettitt, Jessica A., Merrett, Neil D., Toon, Christopher, Epari, Krishna, Nguyen, Nam Q., Barbour, Andrew, Zeps, Nikolajs, Jamieson, Nigel B., Graham, Janet S., Niclou, Simone P., Bjerkvig, Rolf, Grützmann, Robert, Aust, Daniela, Hruban, Ralph H., Maitra, Anirban, Iacobuzio-Donahue, Christine A., Wolfgang, Christopher L., Morgan, Richard A., Lawlor, Rita T., Corbo, Vincenzo, Bassi, Claudio, Falconi, Massimo, Zamboni, Giuseppe, Tortora, Giampaolo, Tempero, Margaret A., Gill, Anthony J., Eshleman, James R., Pilarsky, Christian, Scarpa, Aldo, Musgrove, Elizabeth A., Pearson, John V., Biankin, Andrew V., Grimmond, Sean M.

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Randomized Trial of TAS-102 for Refractory Metastatic Colorectal Cancer von Mayer, Robert J, Van Cutsem, Eric, Falcone, Alfredo, Yoshino, Takayuki, Garcia-Carbonero, Rocio, Mizunuma, Nobuyuki, Yamazaki, Kentaro, Shimada, Yasuhiro, Tabernero, Josep, Komatsu, Yoshito, Sobrero, Alberto, Boucher, Eveline, Peeters, Marc, Tran, Ben, Lenz, Heinz-Josef, Zaniboni, Alberto, Hochster, Howard, Cleary, James M, Prenen, Hans, Benedetti, Fabio, Mizuguchi, Hirokazu, Makris, Lukas, Ito, Masanobu, Ohtsu, Atsushi

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Ramucirumab versus placebo in combination with second-line FOLFIRI in patients with metastatic colorectal carcinoma that progressed during or after first-line therapy with bevacizu... von Tabernero, Josep, Dr, Yoshino, Takayuki, MD, Cohn, Allen Lee, MD, Obermannova, Radka, MD, Bodoky, Gyorgy, Prof, Garcia-Carbonero, Rocio, MD, Ciuleanu, Tudor-Eliade, Prof, Portnoy, David C, MD, Van Cutsem, Eric, Prof, Grothey, Axel, MD, Prausová, Jana, MD, Garcia-Alfonso, Pilar, PhD, Yamazaki, Kentaro, MD, Clingan, Philip R, Prof, Lonardi, Sara, MD, Kim, Tae Won, Prof, Simms, Lorinda, MS, Chang, Shao-Chun, PhD, Nasroulah, Federico, MD

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First-Line Crizotinib versus Chemotherapy in ALK-Positive Lung Cancer von Solomon, Benjamin J, Mok, Tony, Kim, Dong-Wan, Wu, Yi-Long, Nakagawa, Kazuhiko, Mekhail, Tarek, Felip, Enriqueta, Cappuzzo, Federico, Paolini, Jolanda, Usari, Tiziana, Iyer, Shrividya, Reisman, Arlene, Wilner, Keith D, Tursi, Jennifer, Blackhall, Fiona

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Conflict management in public hospitals: the Cyprus case von Pavlakis, A., Kaitelidou, D., Theodorou, M., Galanis, P., Sourtzi, P., Siskou, O.

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Regorafenib monotherapy for previously treated metastatic colorectal cancer (CORRECT): an international, multicentre, randomised, placebo-controlled, phase 3 trial von Grothey, Axel, MD, Cutsem, Eric Van, Prof, Sobrero, Alberto, MD, Siena, Salvatore, MD, Falcone, Alfredo, MD, Ychou, Marc, MD, Humblet, Yves, MD, Bouché, Olivier, MD, Mineur, Laurent, MD, Barone, Carlo, MD, Adenis, Antoine, MD, Tabernero, Josep, MD, Yoshino, Takayuki, MD, Lenz, Heinz-Josef, MD, Goldberg, Richard M, MD, Sargent, Daniel J, PhD, Cihon, Frank, MS, Cupit, Lisa, MD, Wagner, Andrea, MD, Laurent, Dirk, DrMed

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Whole–genome characterization of chemoresistant ovarian cancer von Patch, Ann-Marie, Christie, Elizabeth L., Etemadmoghadam, Dariush, Garsed, Dale W., George, Joshy, Fereday, Sian, Nones, Katia, Cowin, Prue, Alsop, Kathryn, Bailey, Peter J., Kassahn, Karin S., Newell, Felicity, Quinn, Michael C. J., Kazakoff, Stephen, Quek, Kelly, Wilhelm-Benartzi, Charlotte, Curry, Ed, Leong, Huei San, Hamilton, Anne, Mileshkin, Linda, Au-Yeung, George, Kennedy, Catherine, Hung, Jillian, Chiew, Yoke-Eng, Harnett, Paul, Friedlander, Michael, Quinn, Michael, Pyman, Jan, Cordner, Stephen, O’Brien, Patricia, Leditschke, Jodie, Young, Greg, Strachan, Kate, Waring, Paul, Azar, Walid, Mitchell, Chris, Traficante, Nadia, Hendley, Joy, Thorne, Heather, Shackleton, Mark, Miller, David K., Arnau, Gisela Mir, Tothill, Richard W., Holloway, Timothy P., Semple, Timothy, Harliwong, Ivon, Nourse, Craig, Nourbakhsh, Ehsan, Manning, Suzanne, Idrisoglu, Senel, Bruxner, Timothy J. C., Christ, Angelika N., Poudel, Barsha, Holmes, Oliver, Anderson, Matthew, Leonard, Conrad, Lonie, Andrew, Hall, Nathan, Wood, Scott, Taylor, Darrin F., Xu, Qinying, Fink, J. Lynn, Waddell, Nick, Drapkin, Ronny, Stronach, Euan, Gabra, Hani, Brown, Robert, Jewell, Andrea, Nagaraj, Shivashankar H., Markham, Emma, Wilson, Peter J., Ellul, Jason, McNally, Orla, Doyle, Maria A., Vedururu, Ravikiran, Stewart, Collin, Lengyel, Ernst, Pearson, John V., Waddell, Nicola, deFazio, Anna, Grimmond, Sean M., Bowtell, David D. L.

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CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan von Vennin, Claire, Mélénec, Pauline, Rouet, Romain, Nobis, Max, Cazet, Aurélie S., Murphy, Kendelle J., Herrmann, David, Reed, Daniel A., Lucas, Morghan C., Warren, Sean C., Elgundi, Zehra, Pinese, Mark, Kalna, Gabriella, Roden, Daniel, Samuel, Monisha, Zaratzian, Anaiis, Grey, Shane T., Da Silva, Andrew, Leung, Wilfred, Mathivanan, Suresh, Wang, Yingxiao, Braithwaite, Anthony W., Christ, Daniel, Benda, Ales, Parkin, Ashleigh, Phillips, Phoebe A., Whitelock, John M., Gill, Anthony J., Sansom, Owen J., Croucher, David R., Parker, Benjamin L., Pajic, Marina, Morton, Jennifer P., Cox, Thomas R., Timpson, Paul

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Antithrombotic treatments, outcomes, and prognostic factors in acute childhood-onset arterial ischaemic stroke: a multicentre, observational, cohort study von Goldenberg, Neil A, MD, Bernard, Timothy J, MD, Fullerton, Heather J, MD, Gordon, Anne, MSc, deVeber, Gabrielle, MD

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Alectinib in Resected ALK-Positive Non–Small-Cell Lung Cancer von Wu, Yi-Long, Dziadziuszko, Rafal, Ahn, Jin Seok, Barlesi, Fabrice, Nishio, Makoto, Lee, Dae Ho, Lee, Jong-Seok, Zhong, Wenzhao, Horinouchi, Hidehito, Mao, Weimin, Hochmair, Maximilian, de Marinis, Filippo, Migliorino, M. Rita, Bondarenko, Igor, Lu, Shun, Wang, Qun, Ochi Lohmann, Tania, Xu, Tingting, Cardona, Andres, Ruf, Thorsten, Noe, Johannes, Solomon, Benjamin J.

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Methylation of all BRCA1 copies predicts response to the PARP inhibitor rucaparib in ovarian carcinoma von Kondrashova, Olga, Topp, Monique, Nesic, Ksenija, Lieschke, Elizabeth, Ho, Gwo-Yaw, Harrell, Maria I., Zapparoli, Giada V., Hadley, Alison, Holian, Robert, Boehm, Emma, Heong, Valerie, Sanij, Elaine, Pearson, Richard B., Krais, John J., Johnson, Neil, McNally, Orla, Ananda, Sumitra, Alsop, Kathryn, Hutt, Karla J., Kaufmann, Scott H., Lin, Kevin K., Harding, Thomas C., Traficante, Nadia, deFazio, Anna, McNeish, Iain A., Bowtell, David D., Swisher, Elizabeth M., Dobrovic, Alexander, Wakefield, Matthew J., Scott, Clare L.

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The prognostic and predictive value of serum CA19.9 in pancreatic cancer von Humphris, J.L., Chang, D.K., Johns, A.L., Scarlett, C.J., Pajic, M., Jones, M.D., Colvin, E.K., Nagrial, A., Chin, V.T., Chantrill, L.A., Samra, J.S., Gill, A.J., Kench, J.G., Merrett, N.D., Das, A., Musgrove, E.A., Sutherland, R.L., Biankin, A.V.

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