Substrate binding and specificity of rhomboid intramembrane protease revealed by substrate-peptide complex structures von Zoll, Sebastian, Stanchev, Stancho, Began, Jakub, Škerle, Jan, Lepšík, Martin, Peclinovská, Lucie, Majer, Pavel, Strisovsky, Kvido

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Phosphonates and Phosphonate Prodrugs in Medicinal Chemistry: Past Successes and Future Prospects von Krečmerová, Marcela, Majer, Pavel, Rais, Rana, Slusher, Barbara S

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Re-emerging Aspartic Protease Targets: Examining Cryptococcus neoformans Major Aspartyl Peptidase 1 as a Target for Antifungal Drug Discovery von Kryštůfek, Robin, Šácha, Pavel, Starková, Jana, Brynda, Jiří, Hradilek, Martin, Tloušt’ová, Eva, Grzymska, Justyna, Rut, Wioletta, Boucher, Michael J, Drąg, Marcin, Majer, Pavel, Hájek, Miroslav, Řezáčová, Pavlína, Madhani, Hiten D, Craik, Charles S, Konvalinka, Jan

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The unraveling of substrate specificity of histone deacetylase 6 domains using acetylome peptide microarrays and peptide libraries von Kutil, Zsofia, Skultetyova, Lubica, Rauh, David, Meleshin, Marat, Snajdr, Ivan, Novakova, Zora, Mikesova, Jana, Pavlicek, Jiri, Hadzima, Martin, Baranova, Petra, Havlinova, Barbora, Majer, Pavel, Schutkowski, Mike, Barinka, Cyril

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Selectivity of Hydroxamate- and Difluoromethyloxadiazole-Based Inhibitors of Histone Deacetylase 6 In Vitro and in Cells von Ptacek, Jakub, Snajdr, Ivan, Schimer, Jiri, Kutil, Zsofia, Mikesova, Jana, Baranova, Petra, Havlinova, Barbora, Tueckmantel, Werner, Majer, Pavel, Kozikowski, Alan, Barinka, Cyril

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Unraveling the anti-influenza effect of flavonoids: Experimental validation of luteolin and its congeners as potent influenza endonuclease inhibitors von Zima, Václav, Radilová, Kateřina, Kožíšek, Milan, Albiñana, Carlos Berenguer, Karlukova, Elena, Brynda, Jiří, Fanfrlík, Jindřich, Flieger, Miroslav, Hodek, Jan, Weber, Jan, Majer, Pavel, Konvalinka, Jan, Machara, Aleš

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Shared CaM‐ and S100A1‐binding epitopes in the distal TRPM4 N terminus von Bousova, Kristyna, Herman, Petr, Vecer, Jaroslav, Bednarova, Lucie, Monincova, Lenka, Majer, Pavel, Vyklicky, Ladislav, Vondrasek, Jiri, Teisinger, Jan

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Synthesis and In Vitro Evaluation of C-7 and C-8 Luteolin Derivatives as Influenza Endonuclease Inhibitors von Reiberger, Robert, Radilova, Katerina, Kral, Michal, Zima, Vaclav, Majer, Pavel, Brynda, Jiri, Dracinsky, Martin, Konvalinka, Jan, Kozisek, Milan, Machara, Ales

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Structure of glutamate carboxypeptidase II, a drug target in neuronal damage and prostate cancer von Mesters, Jeroen R, Barinka, Cyril, Li, Weixing, Tsukamoto, Takashi, Majer, Pavel, Slusher, Barbara S, Konvalinka, Jan, Hilgenfeld, Rolf

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Identification and Enantiodivergent Synthesis of (5Z,9S)‑Tetradec-5-en-9-olide, a Queen-Specific Volatile of the Termite Silvestritermes minutus von Machara, Aleš, Křivánek, Jan, Dolejšová, Klára, Havlíčková, Jana, Bednárová, Lucie, Hanus, Robert, Majer, Pavel, Kyjaková, Pavlína

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Integrated Activity and Genetic Profiling of Secreted Peptidases in Cryptococcus neoformans Reveals an Aspartyl Peptidase Required for Low pH Survival and Virulence von Clarke, Starlynn C, Dumesic, Phillip A, Homer, Christina M, O'Donoghue, Anthony J, La Greca, Florencia, Pallova, Lenka, Majer, Pavel, Madhani, Hiten D, Craik, Charles S

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Mapping of CaM, S100A1 and PIP2-Binding Epitopes in the Intracellular N- and C-Termini of TRPM4 von Bousova, Kristyna, Barvik, Ivan, Herman, Petr, Hofbauerova, Katerina, Monincova, Lenka, Majer, Pavel, Zouharova, Monika, Vetyskova, Veronika, Postulkova, Klara, Vondrasek, Jiri

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Discovery of a para-Acetoxy-benzyl Ester Prodrug of a Hydroxamate-Based Glutamate Carboxypeptidase II Inhibitor as Oral Therapy for Neuropathic Pain von Rais, Rana, Vávra, Jan, Tichý, Tomáš, Dash, Ranjeet P, Gadiano, Alexandra J, Tenora, Lukáš, Monincová, Lenka, Bařinka, Cyril, Alt, Jesse, Zimmermann, Sarah C, Slusher, C. Ethan, Wu, Ying, Wozniak, Krystyna, Majer, Pavel, Tsukamoto, Takashi, Slusher, Barbara S

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Synthesis and Biological Evaluation of d-Amino Acid Oxidase Inhibitors von Ferraris, Dana, Duvall, Bridget, Ko, Yao-Sen, Thomas, Ajit G, Rojas, Camilo, Majer, Pavel, Hashimoto, Kenji, Tsukamoto, Takashi

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Triggering HIV polyprotein processing by light using rapid photodegradation of a tight-binding protease inhibitor von Schimer, Jiří, Pávová, Marcela, Anders, Maria, Pachl, Petr, Šácha, Pavel, Cígler, Petr, Weber, Jan, Majer, Pavel, Řezáčová, Pavlína, Kräusslich, Hans-Georg, Müller, Barbara, Konvalinka, Jan

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Correction: JHU-083 selectively blocks glutaminase activity in brain CD11b + cells and prevents depression-associated behaviors induced by chronic social defeat stress von Zhu, Xiaolei, Nedelcovych, Michael T, Thomas, Ajit G, Hasegawa, Yuto, Moreno-Megui, Aisa, Coomer, Wade, Vohra, Varun, Saito, Atsushi, Perez, Gabriel, Wu, Ying, Alt, Jesse, Prchalova, Eva, Tenora, Lukáš, Majer, Pavel, Rais, Rana, Rojas, Camilo, Slusher, Barbara S, Kamiya, Atsushi

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ALK5 kinase inhibitory activity and synthesis of 2,3,4-substituted 5,5-dimethyl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazoles von Řezníčková, Eva, Tenora, Lukáš, Pospíšilová, Pavlína, Galeta, Juraj, Jorda, Radek, Berka, Karel, Majer, Pavel, Potáček, Milan, Kryštof, Vladimír

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Co-option of the sphingolipid metabolism for the production of nitroalkene defensive chemicals in termite soldiers von Jirošová, Anna, Jančařík, Andrej, Menezes, Riya C., Bazalová, Olga, Dolejšová, Klára, Vogel, Heiko, Jedlička, Pavel, Buček, Aleš, Brabcová, Jana, Majer, Pavel, Hanus, Robert, Svatoš, Aleš

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Structural Basis of Interactions between Human Glutamate Carboxypeptidase II and Its Substrate Analogs von Barinka, Cyril, Hlouchova, Klara, Rovenska, Miroslava, Majer, Pavel, Dauter, Miroslawa, Hin, Niyada, Ko, Yao-Sen, Tsukamoto, Takashi, Slusher, Barbara S., Konvalinka, Jan, Lubkowski, Jacek

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Sphinganine-Like Biogenesis of (E)-1-Nitropentadec-1-ene in Termite Soldiers of the Genus Prorhinotermes von Jirošová, Anna, Majer, Pavel, Jančařík, Andrej, Dolejšová, Klára, Tykva, Richard, Šobotník, Jan, Jiroš, Pavel, Hanus, Robert

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