mTOR Pathways in Cancer and Autophagy von Paquette, Mathieu, El-Houjeiri, Leeanna, Pause, Arnim

Volltext

AMPK-dependent phosphorylation is required for transcriptional activation of TFEB and TFE3 von Paquette, Mathieu, El-Houjeiri, Leeanna, C. Zirden, Linda, Puustinen, Pietri, Blanchette, Paola, Jeong, Hyeonju, Dejgaard, Kurt, Siegel, Peter M., Pause, Arnim

Volltext

AMPK Maintains Cellular Metabolic Homeostasis through Regulation of Mitochondrial Reactive Oxygen Species von Rabinovitch, Rebecca C., Samborska, Bozena, Faubert, Brandon, Ma, Eric H., Gravel, Simon-Pierre, Andrzejewski, Sylvia, Raissi, Thomas C., Pause, Arnim, St.-Pierre, Julie, Jones, Russell G.

Volltext

mTORC1 Controls Mitochondrial Activity and Biogenesis through 4E-BP-Dependent Translational Regulation von Morita, Masahiro, Gravel, Simon-Pierre, Chénard, Valérie, Sikström, Kristina, Zheng, Liang, Alain, Tommy, Gandin, Valentina, Avizonis, Daina, Arguello, Meztli, Zakaria, Chadi, McLaughlan, Shannon, Nouet, Yann, Pause, Arnim, Pollak, Michael, Gottlieb, Eyal, Larsson, Ola, St-Pierre, Julie, Topisirovic, Ivan, Sonenberg, Nahum

Volltext

The Transcription Factors TFEB and TFE3 Link the FLCN-AMPK Signaling Axis to Innate Immune Response and Pathogen Resistance von El-Houjeiri, Leeanna, Possik, Elite, Vijayaraghavan, Tarika, Paquette, Mathieu, Martina, José A., Kazan, Jalal M., Ma, Eric H., Jones, Russell, Blanchette, Paola, Puertollano, Rosa, Pause, Arnim

Volltext

Loss of hepatic Flcn protects against fibrosis and inflammation by activating autophagy pathways von Paquette, Mathieu, Yan, Ming, Ramírez-Reyes, Josué M. J., El-Houjeiri, Leeanna, Biondini, Marco, Dufour, Catherine R., Jeong, Hyeonju, Pacis, Alain, Giguère, Vincent, Estall, Jennifer L., Siegel, Peter M., Audet-Walsh, Étienne, Pause, Arnim

Volltext

Folliculin: A Regulator of Transcription Through AMPK and mTOR Signaling Pathways von Ramirez Reyes, Josué M J, Cuesta, Rafael, Pause, Arnim

Volltext

Folliculin regulates ampk-dependent autophagy and metabolic stress survival von Possik, Elite, Jalali, Zahra, Nouët, Yann, Yan, Ming, Gingras, Marie-Claude, Schmeisser, Kathrin, Panaite, Lorena, Dupuy, Fanny, Kharitidi, Dmitri, Chotard, Laëtitia, Jones, Russell G, Hall, David H, Pause, Arnim

Volltext

The tumor suppressor folliculin regulates AMPK-dependent metabolic transformation von Yan, Ming, Gingras, Marie-Claude, Dunlop, Elaine A, Nouët, Yann, Dupuy, Fanny, Jalali, Zahra, Possik, Elite, Coull, Barry J, Kharitidi, Dmitri, Dydensborg, Anders Bondo, Faubert, Brandon, Kamps, Miriam, Sabourin, Sylvie, Preston, Rachael S, Davies, David Mark, Roughead, Taren, Chotard, Laëtitia, van Steensel, Maurice A M, Jones, Russell, Tee, Andrew R, Pause, Arnim

Volltext

The AMPK agonist 5‐aminoimidazole‐4‐carboxamide ribonucleotide (AICAR), but not metformin, prevents inflammation‐associated cachectic muscle wasting von Hall, Derek T, Griss, Takla, Ma, Jennifer F, Sanchez, Brenda Janice, Sadek, Jason, Tremblay, Anne Marie K, Mubaid, Souad, Omer, Amr, Ford, Rebecca J, Bedard, Nathalie, Pause, Arnim, Wing, Simon S, Di Marco, Sergio, Steinberg, Gregory R, Jones, Russell G, Gallouzi, Imed‐Eddine

Volltext

HSP90 inhibitors induce GPNMB cell-surface expression by modulating lysosomal positioning and sensitize breast cancer cells to glembatumumab vedotin von Biondini, Marco, Kiepas, Alex, El-Houjeiri, Leeanna, Annis, Matthew G., Hsu, Brian E., Fortier, Anne-Marie, Morin, Geneviève, Martina, José A., Sirois, Isabelle, Aguilar-Mahecha, Adriana, Gruosso, Tina, McGuirk, Shawn, Rose, April A. N., Tokat, Unal M., Johnson, Radia M., Sahin, Ozgur, Bareke, Eric, St-Pierre, Julie, Park, Morag, Basik, Mark, Majewski, Jacek, Puertollano, Rosa, Pause, Arnim, Huang, Sidong, Keler, Tibor, Siegel, Peter M.

Volltext

eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways von Cramer, Zvi, Sadek, Jason, Vazquez, Gabriela Galicia, Di Marco, Sergio, Pause, Arnim, Pelletier, Jerry, Gallouzi, Imed-Eddine

Volltext

FLCN and AMPK Confer Resistance to Hyperosmotic Stress via Remodeling of Glycogen Stores von Possik, Elite, Ajisebutu, Andrew, Manteghi, Sanaz, Gingras, Marie-Claude, Vijayaraghavan, Tarika, Flamand, Mathieu, Coull, Barry, Schmeisser, Kathrin, Duchaine, Thomas, van Steensel, Maurice, Hall, David H, Pause, Arnim

Volltext

Interplay of Endosomal pH and Ligand Occupancy in Integrin α5β1 Ubiquitination, Endocytic Sorting, and Cell Migration von Kharitidi, Dmitri, Apaja, Pirjo M., Manteghi, Sanaz, Suzuki, Kei, Malitskaya, Elena, Roldan, Ariel, Gingras, Marie-Claude, Takagi, Junichi, Lukacs, Gergely L., Pause, Arnim

Volltext

eEF1A is a novel component of the mammalian nuclear protein export machinery von Khacho, Mireille, Mekhail, Karim, Pilon-Larose, Karine, Pause, Arnim, Côté, Jocelyn, Lee, Stephen

Volltext

Haploinsufficiency of the ESCRT Component HD-PTP Predisposes to Cancer von Manteghi, Sanaz, Gingras, Marie-Claude, Kharitidi, Dmitri, Galarneau, Luc, Marques, Maud, Yan, Ming, Cencic, Regina, Robert, Francis, Paquet, Marilène, Witcher, Michael, Pelletier, Jerry, Pause, Arnim

Volltext

An oxygen-regulated switch in the protein synthesis machinery von UNIACKE, James, HOLTERMAN, Chet E, LACHANCE, Gabriel, FRANOVIC, Aleksandra, JACOB, Mathieu D, FABIAN, Marc R, PAYETTE, Josianne, HOLCIK, Martin, PAUSE, Arnim, LEE, Stephen

Volltext

Seventh BHD international symposium: recent scientific and clinical advancement von Woodford, Mark R, Andreou, Avgi, Baba, Masaya, van de Beek, Irma, Di Malta, Chiara, Glykofridis, Iris, Grimes, Hannah, Henske, Elizabeth P, Iliopoulos, Othon, Kurihara, Masatoshi, Lazor, Romain, Linehan, W Marston, Matsumoto, Kenki, Marciniak, Stefan J, Namba, Yukiko, Pause, Arnim, Rajan, Neil, Ray, Anindita, Schmidt, Laura S, Shi, Wei, Steinlein, Ortrud K, Thierauf, Julia, Zoncu, Roberto, Webb, Anna, Mollapour, Mehdi

Volltext

Characterization of a von hippel lindau pathway involved in extracellular matrix remodeling, cell invasion, and angiogenesis von KURBAN, Ghada, HUDON, Valérie, DUPLAN, Eric, OHH, Michael, PAUSE, Arnim

Volltext

Hepatitis C therapeutics: current status and emerging strategies von Tan, Seng-Lai, Pause, Arnim, Shi, Yuguang, Sonenberg, Nahum

Volltext