OC.09.2 THE EXTRACELLULAR MATRIX PROTEIN EMILIN2 AS A REGULATOR OF THE MYELOID RESPONSE IN A MODEL OF INFLAMMATION-INDUCED COLON CARCINOGENESIS von Andreuzzi, E, Tarticchio, G, Di Carlo, E, Todaro, F, Marastoni, S, Paulitti, A, Pellicani, R, Colombatti, A, Cannizzaro, R, Mongiat, M

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OC.16.2 EMILIN2 DEFICIENCY PROMOTES TUMOR GROWTH IN AN INDUCED INFLAMMATORY MODEL OF COLON CARCINOGENESIS von Andreuzzi, E, Paulitti, A, Marastoni, S, Colladel, R, Todaro, F, Di Carlo, E, Colombatti, A, Cannizzaro, R, Mongiat, M

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141 - Mesenchymal Stem/Stromal Cells: EXPANSION OF ADIPOSE-DERIVED MESENCHYMAL STEM CELLS USING A GMP-COMPATIBLE BIOREACTOR: NANT-XL von Grieco, F.A., Barchiesi, A., Botton, O., Vo, S., Mauro, P., Paulitti, A., Adamsky, S., Hick, A.

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Mesenchymal Stem/Stromal Cells: EXPANSION OF ADIPOSE-DERIVED MESENCHYMAL STEM CELLS USING A GMP-COMPATIBLE BIOREACTOR: NANT-XL von Grieco, F.A., Barchiesi, A., Botton, O., Vo, S., Mauro, P., Paulitti, A., Adamsky, S., Hick, A.

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104 - Mesenchymal Stem/Stromal Cells: AUTOMATED PRODUCTION OF ADIPOSE DERIVED MESENCHYMAL STROMAL CELLS WITH NANT 001 BIOREACTOR FOR CLINICAL USE IN ACCORDANCE WITH GOOD MANUFACTUR... von Baldi, J., Lavazza, C., Montelatici, E., Budelli, S., Montemurro, T., Carrino, E., La Rosa, S., Paulitti, A., Zingaretti, N., Lazzari, L.

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Mesenchymal Stem/Stromal Cells: AUTOMATED PRODUCTION OF ADIPOSE DERIVED MESENCHYMAL STROMAL CELLS WITH NANT 001 BIOREACTOR FOR CLINICAL USE IN ACCORDANCE WITH GOOD MANUFACTURING PR... von Baldi, J., Lavazza, C., Montelatici, E., Budelli, S., Montemurro, T., Carrino, E., La Rosa, S., Paulitti, A., Zingaretti, N., Lazzari, L.

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Validation of the nant 001 bioreactor system for automated adipose-derived mesenchymal stem cell expansion von Fitzgerald, J.C., Duffy, N.C., Paulitti, A., Curcio, F., Cattaruzzi, G., Barry, F.

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Application of a novel bioreactor system for automated expansion of adipose- derived mesenchymal stem cells under gmp-compliant conditions von Fitzgerald, J.C., Duffy, N.C., Paulitti, A., Vitrani, F., Curcio, F., Cattaruzzi, G., Sfiligoj, A., Jones, D., Mclnerney, V., Kelly, J., Finnerty, A., McDonagh, K., McCabe, U., Duggan, M., Connolly, L., Barry, F.

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Extracellular Matrix, a Hard Player in Angiogenesis von Mongiat, Maurizio, Andreuzzi, Eva, Tarticchio, Giulia, Paulitti, Alice

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Colorectal cancer development is affected by the ECM molecule EMILIN-2 hinging on macrophage polarization via the TLR-4/MyD88 pathway von Andreuzzi, Eva, Fejza, Albina, Polano, Maurizio, Poletto, Evelina, Camicia, Lucrezia, Carobolante, Greta, Tarticchio, Giulia, Todaro, Federico, Di Carlo, Emma, Scarpa, Melania, Scarpa, Marco, Paulitti, Alice, Capuano, Alessandra, Canzonieri, Vincenzo, Maiero, Stefania, Fornasarig, Mara, Cannizzaro, Renato, Doliana, Roberto, Colombatti, Alfonso, Spessotto, Paola, Mongiat, Maurizio

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Multimerin-2 maintains vascular stability and permeability von Pellicani, Rosanna, Poletto, Evelina, Andreuzzi, Eva, Paulitti, Alice, Doliana, Roberto, Bizzotto, Dario, Braghetta, Paola, Colladel, Roberta, Tarticchio, Giulia, Sabatelli, Patrizia, Bucciotti, Francesco, Bressan, Giorgio, Iozzo, Renato V., Colombatti, Alfonso, Bonaldo, Paolo, Mongiat, Maurizio

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The ablation of the matricellular protein EMILIN2 causes defective vascularization due to impaired EGFR-dependent IL-8 production affecting tumor growth von Paulitti, Alice, Andreuzzi, Eva, Bizzotto, Dario, Pellicani, Rosanna, Tarticchio, Giulia, Marastoni, Stefano, Pastrello, Chiara, Jurisica, Igor, Ligresti, Giovanni, Bucciotti, Francesco, Doliana, Roberto, Colladel, Roberta, Braghetta, Paola, Poletto, Evelina, Di Silvestre, Alessia, Bressan, Giorgio, Colombatti, Alfonso, Bonaldo, Paolo, Mongiat, Maurizio

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Preclinical activity of the repurposed drug auranofin in classical Hodgkin lymphoma von Celegato, Marta, Borghese, Cinzia, Casagrande, Naike, Mongiat, Maurizio, Kahle, Xaver U., Paulitti, Alice, Spina, Michele, Colombatti, Alfonso, Aldinucci, Donatella

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Emilin2 fosters vascular stability by promoting pericyte recruitment von Fejza, Albina, Camicia, Lucrezia, Carobolante, Greta, Poletto, Evelina, Paulitti, Alice, Schinello, Giorgia, Di Siena, Emanuele, Cannizzaro, Renato, Iozzo, Renato V., Baldassarre, Gustavo, Andreuzzi, Eva, Spessotto, Paola, Mongiat, Maurizio

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EMILIN2 down-modulates the Wnt signalling pathway and suppresses breast cancer cell growth and migration von Marastoni, Stefano, Andreuzzi, Eva, Paulitti, Alice, Colladel, Roberta, Pellicani, Rosanna, Todaro, Federico, Schiavinato, Alvise, Bonaldo, Paolo, Colombatti, Alfonso, Mongiat, Maurizio

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MULTIMERIN2 binds VEGF-A primarily via the carbohydrate chains exerting an angiostatic function and impairing tumor growth von Colladel, Roberta, Pellicani, Rosanna, Andreuzzi, Eva, Paulitti, Alice, Tarticchio, Giulia, Todaro, Federico, Colombatti, Alfonso, Mongiat, Maurizio

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Ischemic wound revascularization by the stromal vascular fraction relies on host-donor hybrid vessels von Vuerich, Roman, Groppa, Elena, Vodret, Simone, Ring, Nadja Annelies Ruth, Stocco, Chiara, Bossi, Fleur, Agostinis, Chiara, Cauteruccio, Matteo, Colliva, Andrea, Ramadan, Mohammad, Simoncello, Francesca, Benvenuti, Federica, Agnelli, Anna, Dore, Franca, Mazzarol, Flavia, Moretti, Massimo, Paulitti, Alice, Palmisano, Silvia, De Manzini, Nicolò, Chiesa, Mattia, Casaburo, Manuel, Raucci, Angela, Lorizio, Daniela, Pompilio, Giulio, Bulla, Roberta, Papa, Giovanni, Zacchigna, Serena

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GMP-Compliant Production of Autologous Adipose-Derived Stromal Cells in the NANT 001 Closed Automated Bioreactor von Fitzgerald, Joan C, Duffy, Niamh, Cattaruzzi, Giacomo, Vitrani, Francesco, Paulitti, Alice, Mazzarol, Flavia, Mauro, Prisca, Sfiligoj, Antonio, Curcio, Francesco, Jones, Deirdre M, McInerney, Veronica, Krawczyk, Janusz, Kelly, Jack, Finnerty, Andrew, McDonagh, Katya, McCabe, Una, Duggan, Matthew, Connolly, Lauren, Shaw, Georgina, Murphy, Mary, Barry, Frank

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EMILIN2, extracellular matrix protein, as a regulator of the myeloid response in a model of inflammation-induced colon carcinogenesis von Cannizzaro, Renato, Andreuzzi, Eva, Tarticchio, Giulia, Paulitti, Alice, Marastoni, Stefano, Pellicani, Rosanna, Di Carlo, Emma, Magris, Raffaella, Maiero, Stefania, Fornasarig, Mara, Colombatti, Alfonso, Mongiat, Maurizio

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Sleeping beauty genetic screen identifies miR-23b::BTBD7 gene interaction as crucial for colorectal cancer metastasis von Grisard, Eleonora, Coan, Michela, Cesaratto, Laura, Rigo, Ilenia, Zandonà, Luigi, Paulitti, Alice, Andreuzzi, Eva, Rampioni Vinciguerra, Gian Luca, Poletto, Evelina, Del Ben, Fabio, Brisotto, Giulia, Biscontin, Eva, Turetta, Matteo, Dassi, Erik, Mirnezami, Alex, Canzonieri, Vincenzo, Vecchione, Andrea, Baldassarre, Gustavo, Mongiat, Maurizio, Spizzo, Riccardo, Nicoloso, Milena S.

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