Sphingolipids and expression regulation of genes in cancer von Patwardhan, Gauri A., Liu, Yong-Yu

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Identification and Validation of a Novel Biologics Target in Triple Negative Breast Cancer von Wali, Vikram B., Patwardhan, Gauri A., Pelekanou, Vasiliki, Karn, Thomas, Cao, Jian, Ocana, Alberto, Yan, Qin, Nelson, Bryce, Hatzis, Christos, Pusztai, Lajos

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Glucosylceramide synthase upregulates MDR1 expression in the regulation of cancer drug resistance through cSrc and beta-catenin signaling von Liu, Yong-Yu, Gupta, Vineet, Patwardhan, Gauri A, Bhinge, Kaustubh, Zhao, Yunfeng, Bao, Jianxiong, Mehendale, Harihara, Cabot, Myles C, Li, Yu-Teh, Jazwinski, S Michal

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Suppression of Glucosylceramide Synthase Restores p53-Dependent Apoptosis in Mutant p53 Cancer Cells von LIU, Yong-Yu, PATWARDHAN, Gauri A, BHINGE, Kaustubh, GUPTA, Vineet, XIN GU, MICHAL JAZWINSKI, S

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Treatment scheduling effects on the evolution of drug resistance in heterogeneous cancer cell populations von Patwardhan, Gauri A., Marczyk, Michal, Wali, Vikram B., Stern, David F., Pusztai, Lajos, Hatzis, Christos

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Sphingolipids and mitochondrial apoptosis von Patwardhan, Gauri A., Beverly, Levi J., Siskind, Leah J.

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A new mixed-backbone oligonucleotide against glucosylceramide synthase sensitizes multidrug-resistant tumors to apoptosis von Patwardhan, Gauri A, Zhang, Qian-Jin, Yin, Dongmei, Gupta, Vineet, Bao, Jianxiong, Senkal, Can E, Ogretmen, Besim, Cabot, Myles C, Shah, Girish V, Sylvester, Paul W, Jazwinski, S Michal, Liu, Yong-Yu

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Direct quantitative determination of ceramide glycosylation in vivo: a new approach to evaluate cellular enzyme activity of glucosylceramide synthase von Gupta, Vineet, Patwardhan, Gauri A., Zhang, Qian-Jin, Cabot, Myles C., Jazwinski, S. Michal, Liu, Yong-Yu

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Ceramide channels: destabilization by Bcl-xL and role in apoptosis von Chang, Kai-Ti, Anishkin, Andriy, Patwardhan, Gauri A., Beverly, Levi J., Siskind, Leah J., Colombini, Marco

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Systematic Drug Screening Identifies Tractable Targeted Combination Therapies in Triple-Negative Breast Cancer von Wali, Vikram B, Langdon, Casey G, Held, Matthew A, Platt, James T, Patwardhan, Gauri A, Safonov, Anton, Aktas, Bilge, Pusztai, Lajos, Stern, David F, Hatzis, Christos

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Multi-Omics Investigation of Innate Navitoclax Resistance in Triple-Negative Breast Cancer Cells von Marczyk, Michal, Patwardhan, Gauri A., Zhao, Jun, Qu, Rihao, Li, Xiaotong, Wali, Vikram B., Gupta, Abhishek K., Pillai, Manoj M., Kluger, Yuval, Yan, Qin, Hatzis, Christos, Pusztai, Lajos, Gunasekharan, Vignesh

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Ceramide modulates pre-mRNA splicing to restore the expression of wild-type tumor suppressor p53 in deletion-mutant cancer cells von Patwardhan, Gauri A., Hosain, Salman B., Liu, David X., Khiste, Sachin K., Zhao, Yunfeng, Bielawski, Jacek, Jazwinski, S. Michal, Liu, Yong-Yu

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Glucosylceramide synthase, a factor in modulating drug resistance, is overexpressed in metastatic breast carcinoma von LIU, Yong-Yu, PATWARDHAN, Gauri A, PING XIE, XIN GU, GIULIANO, Armando E, CABOT, Myles C

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Mitotic read-out genes confer poor outcome in luminal A breast cancer tumors von Pérez-Peña, Javier, Alcaraz-Sanabria, Ana, Nieto-Jiménez, Cristina, Páez, Raquel, Corrales-Sánchez, Verónica, Serrano-Oviedo, Leticia, Wali, Vikram B, Patwardhan, Gauri A, Amir, Eitan, Győrffy, Balázs, Pandiella, Atanasio, Ocaña, Alberto

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Abstract 2073: A systematic investigation of the effect of scheduling of targeted combination therapies on response and dynamics of relapse in triple negative breast cancer cells von Patwardhan, Gauri A., Wali, Vikram B., Pusztai, Lajos, Hatzis, Christos

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Abstract 1141: Evaluation of GABRP as a novel therapeutic target in triple negative breast cancer von Wali, Vikram B., Patwardhan, Gauri A., Hatzis, Christos, Pusztai, Lajos

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Abstract 6333: Genomic, transcriptomic, and epigenetic profiling of triple-negative breast cancer cells after Navitoclax treatment von Marczyk, Michal, Gunasekharan, Vignesh, Zhao, Jun, Qu, Rihao, Li, Xiaotong, Patwardhan, Gauri A., Wali, Vikram B., Gupta, Abhishek K., Pillai, Manoj M., Kluger, Yuval, Hatzis, Christos, Pusztai, Lajos

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Abstract 3199: Ceramide restores the expression of wild-type p53 tumor suppressor in mRNA splicing through PP1 and ASF/SF2 von Liu, Yong-Yu, Patwardhan, Gauri A.

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Abstract 2569: Disruption of ceramide glycosylation restores p53-dependent apoptosis in p53 mutant drug-resistant cancer cells: Alternative splicing determines the feature of p53 a... von Patwardhan, Gauri A., Gupta, Vineet, Hsia, Shaochung, Gu, Xin, Jazwinski, Michal, Liu, Yong-Yu

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Glucosylceramide synthase upregulates MDR1 expression in the regulation of cancer drug resistance through cSrc and [beta]-catenin signaling von Liu, Yong-Yu, Gupta, Vineet, Patwardhan, Gauri A, Bhinge, Kaustubh, Zhao, Yunfeng, Bao, Jianxiong, Mehendale, Harihara, Cabot, Myles C, Li, Yu-Teh, Jazwinski, S Michal

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