Anti‐tumour efficacy on glioma models of PHA‐848125, a multi‐kinase inhibitor able to cross the blood–brain barrier von Albanese, C, Alzani, R, Amboldi, N, Degrassi, A, Festuccia, C, Fiorentini, F, Gravina, GL, Mercurio, C, Pastori, W, Brasca, MG, Pesenti, E, Galvani, A, Ciomei, M

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NMS-P088, a CSF-1R, FLT3 and KIT inhibitor with outstanding activity on gatekeeper resistance mutations, high tolerability, and potential for combination therapies von Ardini, E, Lombardi Borgia, A, Texido, G, Alzani, R, Avanzi, N, Amboldi, N, Cribioli, S, Mancini, L, Casero, D, Pastori, W, Montemartini, M, Montagnoli, A, Donati, D, Galvani, A, Isacchi, A, Ciomei, M

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388 - NMS-P088, a CSF-1R, FLT3 and KIT inhibitor with outstanding activity on gatekeeper resistance mutations, high tolerability, and potential for combination therapies von Ardini, E., Lombardi Borgia, A., Texido, G., Alzani, R., Avanzi, N., Amboldi, N., Cribioli, S., Mancini, L., Casero, D., Pastori, W., Montemartini, M., Montagnoli, A., Donati, D., Galvani, A., Isacchi, A., Ciomei, M.

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3-Aminopyrazole Inhibitors of CDK2/Cyclin A as Antitumor Agents. 2. Lead Optimization von Pevarello, Paolo, Brasca, Maria Gabriella, Orsini, Paolo, Traquandi, Gabriella, Longo, Antonio, Nesi, Marcella, Orzi, Fabrizio, Piutti, Claudia, Sansonna, Pietro, Varasi, Mario, Cameron, Alexander, Vulpetti, Anna, Roletto, Fulvia, Alzani, Rachele, Ciomei, Marina, Albanese, Clara, Pastori, Wilma, Marsiglio, Aurelio, Pesenti, Enrico, Fiorentini, Francesco, Bischoff, Jim R, Mercurio, Ciro

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3-Aminopyrazole Inhibitors of CDK2/Cyclin A as Antitumor Agents. 1. Lead Finding von Pevarello, Paolo, Brasca, Maria Gabriella, Amici, Raffaella, Orsini, Paolo, Traquandi, Gabriella, Corti, Luca, Piutti, Claudia, Sansonna, Pietro, Villa, Manuela, Pierce, Betsy S, Pulici, Maurizio, Giordano, Patrizia, Martina, Katia, Fritzen, Edward L, Nugent, Richard A, Casale, Elena, Cameron, Alexander, Ciomei, Marina, Roletto, Fulvia, Isacchi, Antonella, Fogliatto, GianPaolo, Pesenti, Enrico, Pastori, Wilma, Marsiglio, Aurelio, Leach, Karen L, Clare, Paula M, Fiorentini, Francesco, Varasi, Mario, Vulpetti, Anna, Warpehoski, Martha A

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Optimization of Diarylthiazole B-Raf Inhibitors: Identification of a Compound Endowed with High Oral Antitumor Activity, Mitigated hERG Inhibition, and Low Paradoxical Effect von Pulici, Maurizio, Traquandi, Gabriella, Marchionni, Chiara, Modugno, Michele, Lupi, Rosita, Amboldi, Nadia, Casale, Elena, Colombo, Nicoletta, Corti, Luca, Fasolini, Marina, Gasparri, Fabio, Pastori, Wilma, Scolaro, Alessandra, Donati, Daniele, Felder, Eduard, Galvani, Arturo, Isacchi, Antonella, Pesenti, Enrico, Ciomei, Marina

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294 POSTER Biological characterization of the dual CDK2/TRKA inhibitor PHA-848125 von Alzani, R, Albanese, C, Locatelli, G, Pastori, W, Amboldi, N, Croci, W, Fiorentini, F, Roletto, F, DePonti, C, Mercurio, C

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Decreased tyrosine phosphorylation in tumour cells resistant to FCE 24517 (tallimustine) von CIOMEI, M, PASTORI, W, CAPOLONGO, L, GERONI, C, MELEGARO, G, PENNELLA, G, GRANDI, M

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3-Aminopyrazole Inhibitors of CDK2/Cyclin A as Antitumor Agents. 2. Lead Optimization von Pevarello, Paolo, Brasca, Maria Gabriella, Orsini, Paolo, Traquandi, Gabriella, Longo, Antonio, Nesi, Marcella, Orzi, Fabrizio, Piutti, Claudia, Sansonna, Pietro, Varasi, Mario, Cameron, Alexander, Vulpetti, Anna, Roletto, Fulvia, Alzani, Rachele, Ciomei, Marina, Albanese, Clara, Pastori, Wilma, Marsiglio, Aurelio, Pesenti, Enrico, Fiorentini, Francesco, Bischoff, Jim R, Mercurio, Ciro

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Inclusion of soy oil levels on the acceptability and digestibility of diets for equines von Gobesso, A, Pastori, W, Ribeiro, R, Prezotto, L

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New sulfonated distamycin a derivatives with bFGF complexing activity von Ciomei, Marina, Pastori, Wilma, Mariani, Mariangela, Sola, Francesco, Grandi, Maria, Mongelli, Nicola

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The Impact of Microprocessor Technology on Receiver/Amplifier Noise Measurement von Pastori, William E.

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A tumour-specific inhibiting factor: MS-TIF von Ciomei, M., Montecucchi, P.C., Pastori, W., Giuliani, F.C.

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Characteristics of patients with atrial high rate episodes detected by implanted defibrillator and resynchronisation devices von Miyazawa, K, Pastori, D, Martin, D, Choucair, W, Halperin, J, Lip, G

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Hydroxypropyl-β-cyclodextrin protects from kidney disease in experimental Alport syndrome and focal segmental glomerulosclerosis von Mitrofanova, Alla, Molina, Judith, Varona Santos, Javier, Guzman, Johanna, Morales, Ximena A., Ducasa, G. Michelle, Bryn, Jonathan, Sloan, Alexis, Volosenco, Ion, Kim, Jin-Ju, Ge, Mengyuan, Mallela, Shamroop K., Kretzler, Matthias, Eddy, Sean, Martini, Sebastian, Wahl, Patricia, Pastori, Santiago, Mendez, Armando J., Burke, George W., Merscher, Sandra, Fornoni, Alessia

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Short versus long-term anticoagulation for left ventricular thrombosis resolution during vitamin k antagonist therapy von Valeriani, E, Pastori, D, Astorri, G, Ageno, W, Donadini, M P, Santagata, D P, Becattini, C, Satula, K, De Candia, E, D'innocenzo, L, Tufano, A, Marcucci, R, Berteotti, M, Bucci, T, Pignatelli, P

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The DQQ is a Valid Tool to Collect Population-Level Food Group Consumption Data: A Study Among Women in Ethiopia, Vietnam, and Solomon Islands von Uyar, Betül T.M., Talsma, Elise F., Herforth, Anna W., Trijsburg, Laura E., Vogliano, Chris, Pastori, Giulia, Bekele, Tesfaye Hailu, Huong, Le Thi, Brouwer, Inge D.

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The Atrial Fibrillation Better Care (ABC) pathway in atrial fibrillation: a systematic review and meta-analysis of 285,000 patients von Romiti, GF, Pastori, D, Rivera-Caravaca, JM, Ding, WY, Gue, YX, Menichelli, D, Gumprecht, J, Koziel, M, Yang, PS, Guo, Y, Lip, GYH, Proietti, M

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Major adverse cardiovascular events with renal failure in atrial fibrillation von Ding, W Y, Lip, GYH, Pastori, D, Shantsila, A

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Chromosome evolution in the erythrinid fish, Erythrinus erythrinus (Teleostei: Characiformes) von Bertollo, L A C, Oliveira, C, Molina, W F, Margarido, V P, Fontes, M S, Pastori, M C, Falcão, J das N, Fenocchio, A S

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