Functional trade‐offs in the limb muscles of dogs selected for running vs. fighting von Pasi, B. M., Carrier, D. R.

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A Functional Landscape of Resistance to ALK Inhibition in Lung Cancer von Wilson, Frederick H., Johannessen, Cory M., Piccioni, Federica, Tamayo, Pablo, Kim, Jong Wook, Van Allen, Eliezer M., Corsello, Steven M., Capelletti, Marzia, Calles, Antonio, Butaney, Mohit, Sharifnia, Tanaz, Gabriel, Stacey B., Mesirov, Jill P., Hahn, William C., Engelman, Jeffrey A., Meyerson, Matthew, Root, David E., Jänne, Pasi A., Garraway, Levi A.

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Oncogenic and drug-sensitive NTRK1 rearrangements in lung cancer von Vaishnavi, Aria, Capelletti, Marzia, Le, Anh T, Kako, Severine, Butaney, Mohit, Ercan, Dalia, Mahale, Sakshi, Davies, Kurtis D, Aisner, Dara L, Pilling, Amanda B, Berge, Eamon M, Kim, Jhingook, Sasaki, Hidefumi, Park, Seung-il, Kryukov, Gregory, Garraway, Levi A, Hammerman, Peter S, Haas, Julia, Andrews, Steven W, Lipson, Doron, Stephens, Philip J, Miller, Vince A, Varella-Garcia, Marileila, Jänne, Pasi A, Doebele, Robert C

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Loss of Lkb1 and Pten Leads to Lung Squamous Cell Carcinoma with Elevated PD-L1 Expression von Xu, Chunxiao, Fillmore, Christine M., Koyama, Shohei, Wu, Hongbo, Zhao, Yanqiu, Chen, Zhao, Herter-Sprie, Grit S., Akbay, Esra A., Tchaicha, Jeremy H., Altabef, Abigail, Reibel, Jacob B., Walton, Zandra, Ji, Hongbin, Watanabe, Hideo, Jänne, Pasi A., Castrillon, Diego H., Rustgi, Anil K., Bass, Adam J., Freeman, Gordon J., Padera, Robert F., Dranoff, Glenn, Hammerman, Peter S., Kim, Carla F., Wong, Kwok-Kin

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Dacomitinib versus erlotinib in patients with advanced-stage, previously treated non-small-cell lung cancer (ARCHER 1009): a randomised, double-blind, phase 3 trial von Ramalingam, Suresh S, Prof, Jänne, Pasi A, Prof, Mok, Tony, Prof, O'Byrne, Kenneth, Prof, Boyer, Michael J, Prof, Von Pawel, Joachim, Prof, Pluzanski, Adam, MD, Shtivelband, Mikhail, MD, Docampo, Lara Iglesias, MD, Bennouna, Jaafar, MD, Zhang, Hui, PhD, Liang, Jane Q, PhD, Doherty, Jim P, PhD, Taylor, Ian, PhD, Mather, Cecile B, MS, Goldberg, Zelanna, MD, O'Connell, Joseph, MD, Paz-Ares, Luis, Prof

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Valoctocogene Roxaparvovec Gene Therapy for Hemophilia A von Ozelo, Margareth C, Mahlangu, Johnny, Pasi, K. John, Giermasz, Adam, Leavitt, Andrew D, Laffan, Michael, Symington, Emily, Quon, Doris V, Wang, Jiaan-Der, Peerlinck, Kathelijne, Pipe, Steven W, Madan, Bella, Key, Nigel S, Pierce, Glenn F, O’Mahony, Brian, Kaczmarek, Radoslaw, Henshaw, Joshua, Lawal, Adebayo, Jayaram, Kala, Huang, Mei, Yang, Xinqun, Wong, Wing Y, Kim, Benjamin

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A Prospective Evaluation of Circulating Tumor Cells and Cell-Free DNA in EGFR-Mutant Non-Small Cell Lung Cancer Patients Treated with Erlotinib on a Phase II Trial von Yanagita, Masahiko, Redig, Amanda J, Paweletz, Cloud P, Dahlberg, Suzanne E, O'Connell, Allison, Feeney, Nora, Taibi, Myriam, Boucher, David, Oxnard, Geoffrey R, Johnson, Bruce E, Costa, Daniel B, Jackman, David M, Jänne, Pasi A

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Amplification of Wild-type KRAS Imparts Resistance to Crizotinib in MET Exon 14 Mutant Non-Small Cell Lung Cancer von Bahcall, Magda, Awad, Mark M, Sholl, Lynette M, Wilson, Frederick H, Xu, Man, Wang, Stephen, Palakurthi, Sangeetha, Choi, Jihyun, Ivanova, Elena V, Leonardi, Giulia C, Ulrich, Bryan C, Paweletz, Cloud P, Kirschmeier, Paul T, Watanabe, Masayuki, Baba, Hideo, Nishino, Mizuki, Nagy, Rebecca J, Lanman, Richard B, Capelletti, Marzia, Chambers, Emily S, Redig, Amanda J, VanderLaan, Paul A, Costa, Daniel B, Imamura, Yu, Jänne, Pasi A

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Potent and Selective Covalent Quinazoline Inhibitors of KRAS G12C von Zeng, Mei, Lu, Jia, Li, Lianbo, Feru, Frederic, Quan, Chunshan, Gero, Thomas W., Ficarro, Scott B., Xiong, Yuan, Ambrogio, Chiara, Paranal, Raymond M., Catalano, Marco, Shao, Jay, Wong, Kwok-Kin, Marto, Jarrod A., Fischer, Eric S., Jänne, Pasi A., Scott, David A., Westover, Kenneth D., Gray, Nathanael S.

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Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints von Koyama, Shohei, Akbay, Esra A., Li, Yvonne Y., Herter-Sprie, Grit S., Buczkowski, Kevin A., Richards, William G., Gandhi, Leena, Redig, Amanda J., Rodig, Scott J., Asahina, Hajime, Jones, Robert E., Kulkarni, Meghana M., Kuraguchi, Mari, Palakurthi, Sangeetha, Fecci, Peter E., Johnson, Bruce E., Janne, Pasi A., Engelman, Jeffrey A., Gangadharan, Sidharta P., Costa, Daniel B., Freeman, Gordon J., Bueno, Raphael, Hodi, F. Stephen, Dranoff, Glenn, Wong, Kwok-Kin, Hammerman, Peter S.

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Whole-genome sequence of the bovine blood fluke Schistosoma bovis supports interspecific hybridization with S. haematobium von Oey, Harald, Zakrzewski, Martha, Gravermann, Kerstin, Young, Neil D, Korhonen, Pasi K, Gobert, Geoffrey N, Nawaratna, Sujeevi, Hasan, Shihab, Martínez, David M, You, Hong, Lavin, Martin, Jones, Malcolm K, Ragan, Mark A, Stoye, Jens, Oleaga, Ana, Emery, Aidan M, Webster, Bonnie L, Rollinson, David, Gasser, Robin B, McManus, Donald P, Krause, Lutz

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Effects of Erlotinib in EGFR Mutated Non-Small Cell Lung Cancers with Resistance to Gefitinib von COSTA, Daniel B, NGUYEN, Kim-Son H, HUBERMAN, Mark S, PAO, William, TENEN, Daniel G, KOBAYASHI, Susumu, CHO, Byoung C, SEQUIST, Lecia V, JACKMAN, David M, RIELY, Gregory J, YEAP, Beow Y, HALMOS, Balazs, KIM, Joo H, JÄNNE, Pasi A

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RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer von Niederst, Matthew J., Sequist, Lecia V., Poirier, John T., Mermel, Craig H., Lockerman, Elizabeth L., Garcia, Angel R., Katayama, Ryohei, Costa, Carlotta, Ross, Kenneth N., Moran, Teresa, Howe, Emily, Fulton, Linnea E., Mulvey, Hillary E., Bernardo, Lindsay A., Mohamoud, Farhiya, Miyoshi, Norikatsu, VanderLaan, Paul A., Costa, Daniel B., Jänne, Pasi A., Borger, Darrell R., Ramaswamy, Sridhar, Shioda, Toshi, Iafrate, Anthony J., Getz, Gad, Rudin, Charles M., Mino-Kenudson, Mari, Engelman, Jeffrey A.

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EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy von Paez, J. Guillermo, Jänne, Pasi A., Lee, Jeffrey C., Tracy, Sean, Greulich, Heidi, Gabriel, Stacey, Herman, Paula, Kaye, Frederic J., Lindeman, Neal, Boggon, Titus J., Naoki, Katsuhiko, Sasaki, Hidefumi, Fujii, Yoshitaka, Eck, Michael J., Sellers, William R., Johnson, Bruce E., Meyerson, Matthew

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Design of a “Two-in-One” Mutant-Selective Epidermal Growth Factor Receptor Inhibitor That Spans the Orthosteric and Allosteric Sites von Wittlinger, Florian, Heppner, David E, To, Ciric, Günther, Marcel, Shin, Bo Hee, Rana, Jaimin K, Schmoker, Anna M, Beyett, Tyler S, Berger, Lena M, Berger, Benedict-Tilman, Bauer, Nicolas, Vasta, James D, Corona, Cesear R, Robers, Matthew B, Knapp, Stefan, Jänne, Pasi A, Eck, Michael J, Laufer, Stefan A

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A Rapid and Sensitive Enzymatic Method for Epidermal Growth Factor Receptor Mutation Screening von JÄNNE, Pasi A, BORRAS, Ana M, DISTEL, Robert J, MEYERSON, Matthew, JOHNSON, Bruce E, YANAN KUANG, ROGERS, Andrew M, JOSHI, Victoria A, LIYANAGE, Hema, LINDEMAN, Neal, LEE, Jeffrey C, HALMOS, Balazs, MAHER, Elizabeth A

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Clinical Characteristics and Outcomes of Patients Hospitalized for COVID-19 in Africa: Early Insights from the Democratic Republic of the Congo von Nachega, Jean, Ishoso, Daniel, Otokoye, John, Hermans, Michel, Machekano, Rhoderick, Sam-Agudu, Nadia, Nswe, Christian, Mbala-Kingebeni, Placide, Madinga, Joule, Mukendi, Stephane, Kolie, Marie, Nkwembe, Edith, Mbuyi, Gisele, Nsio, Justus, Tshialala, Didier, Pipo, Michel, Ahuka-Mundeke, Steve, Muyembe-Tamfum, Jean-Jacques, Mofenson, Lynne, Smith, Gerald, Mills, Edward, Mellors, John, Zumla, Alimuddin, Landu, Don, Kayembe, Jean-Marie

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Genomic and transcriptomic analysis of checkpoint blockade response in advanced non-small cell lung cancer von Ravi, Arvind, Hellmann, Matthew D., Arniella, Monica B., Holton, Mark, Freeman, Samuel S., Naranbhai, Vivek, Stewart, Chip, Leshchiner, Ignaty, Kim, Jaegil, Akiyama, Yo, Griffin, Aaron T., Vokes, Natalie I., Sakhi, Mustafa, Kamesan, Vashine, Rizvi, Hira, Ricciuti, Biagio, Forde, Patrick M., Anagnostou, Valsamo, Riess, Jonathan W., Gibbons, Don L., Pennell, Nathan A., Velcheti, Vamsidhar, Digumarthy, Subba R., Mino-Kenudson, Mari, Califano, Andrea, Heymach, John V., Herbst, Roy S., Brahmer, Julie R., Schalper, Kurt A., Velculescu, Victor E., Henick, Brian S., Rizvi, Naiyer, Jänne, Pasi A., Awad, Mark M., Chow, Andrew, Greenbaum, Benjamin D., Luksza, Marta, Shaw, Alice T., Wolchok, Jedd, Hacohen, Nir, Getz, Gad, Gainor, Justin F.

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Glesatinib Exhibits Antitumor Activity in Lung Cancer Models and Patients Harboring MET Exon 14 Mutations and Overcomes Mutation-mediated Resistance to Type I MET Inhibitors in Non... von Engstrom, Lars D, Aranda, Ruth, Lee, Matthew, Tovar, Elizabeth A, Essenburg, Curt J, Madaj, Zachary, Chiang, Harrah, Briere, David, Hallin, Jill, Lopez-Casas, Pedro P, Baños, Natalia, Menendez, Camino, Hidalgo, Manuel, Tassell, Vanessa, Chao, Richard, Chudova, Darya I, Lanman, Richard B, Olson, Peter, Bazhenova, Lyudmilla, Patel, Sandip Pravin, Graveel, Carrie, Nishino, Mizuki, Shapiro, Geoffrey I, Peled, Nir, Awad, Mark M, Jänne, Pasi A, Christensen, James G

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Chemotherapy for locally advanced and metastatic pulmonary carcinoid tumors von Chong, Curtis R, Wirth, Lori J, Nishino, Mizuki, Chen, Aileen B, Sholl, Lynette M, Kulke, Matthew H, McNamee, Ciaran J, Jänne, Pasi A, Johnson, Bruce E

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