IVAC MUTANOME: A first-in-human phase I clinical trial targeting individual mutant neoantigens for the treatment of melanoma von Miller, M., Sahin, U., Derhovanessian, E., Kloke, B-P, Simon, P., Bukur, V., Albrecht, C., Paruzynski, A., Löwer, M., Kuhn, A., Schreeb, K., Attig, S., Brueck, A Kemmer, Bolte, S., Grabbe, S., Höller, C., Utikal, J., Huber, C., Loquai, C., Türeci, Ö

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High performance analysis of genome integrating gene transfer agents von Arens, A, Bartholomae, C, Gabriel, R, Paruzynski, A, Glimm, H, von Kalle, C, Schmidt, M

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Integration site analysis by non-restrictive (nr) LAM-PCR combined with optimized high-throughput sequencing von Paruzynski, A, Arens, A, Gabriel, R, Bartholomae, C, Eckenberg, R, Nowrouzi, A, Scholz, S, Howe, S, Recchia, A, Cattoglio, C, Wang, W, Faber, K, Schwarzwaelder, K, von Kalle, C

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Assessing the genome accessibility of viral integration sites von Gabriel, R, Paruzynski, A, Eckenberg, R, Bartholomae, C C, Nowrouzi, A, Wang, W, Schwarzwaelder, K, Arens, A, Kirsten, R, Deichmann, A, Ball, C R, Howe, S J, Recchia, A, Claudia, C

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A Pilot and Feasibility Study of Oatmeal Consumption in Children to Assess Markers of Bowel Function von Paruzynski, Hannah, Korczak, Renee, Wang, Qi, Slavin, Joanne

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Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer von Sahin, Ugur, Derhovanessian, Evelyna, Miller, Matthias, Kloke, Björn-Philipp, Simon, Petra, Löwer, Martin, Bukur, Valesca, Tadmor, Arbel D., Luxemburger, Ulrich, Schrörs, Barbara, Omokoko, Tana, Vormehr, Mathias, Albrecht, Christian, Paruzynski, Anna, Kuhn, Andreas N., Buck, Janina, Heesch, Sandra, Schreeb, Katharina H., Müller, Felicitas, Ortseifer, Inga, Vogler, Isabel, Godehardt, Eva, Attig, Sebastian, Rae, Richard, Breitkreuz, Andrea, Tolliver, Claudia, Suchan, Martin, Martic, Goran, Hohberger, Alexander, Sorn, Patrick, Diekmann, Jan, Ciesla, Janko, Waksmann, Olga, Brück, Alexandra-Kemmer, Witt, Meike, Zillgen, Martina, Rothermel, Andree, Kasemann, Barbara, Langer, David, Bolte, Stefanie, Diken, Mustafa, Kreiter, Sebastian, Nemecek, Romina, Gebhardt, Christoffer, Grabbe, Stephan, Höller, Christoph, Utikal, Jochen, Huber, Christoph, Loquai, Carmen, Türeci, Özlem

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The balance between the intronic miR-342 and its host gene Evl determines hematopoietic cell fate decision von Herbst, Friederike, Lang, Tonio J. L., Eckert, Elias S. P., Wünsche, Peer, Wurm, Alexander A., Kindinger, Tim, Laaber, Karin, Hemmati, Shayda, Hotz-Wagenblatt, Agnes, Zavidij, Oksana, Paruzynski, Anna, Lu, Junyan, von Kalle, Christof, Zenz, Thorsten, Klein, Christoph, Schmidt, Manfred, Ball, Claudia R., Glimm, Hanno

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High-resolution analysis of the human T-cell receptor repertoire von Ruggiero, Eliana, Nicolay, Jan P., Fronza, Raffaele, Arens, Anne, Paruzynski, Anna, Nowrouzi, Ali, Ürenden, Gökçe, Lulay, Christina, Schneider, Sven, Goerdt, Sergij, Glimm, Hanno, Krammer, Peter H., Schmidt, Manfred, von Kalle, Christof

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Comprehensive genomic access to vector integration in clinical gene therapy von Arens, Anne, Naldini, Luigi, Cattoglio, Claudia, Eckenberg, Ralph, Deichmann, Annette, Bartholomae, Cynthia C, Faber, Katrin, Nowrouzi, Ali, Paruzynski, Anna, Montini, Eugenio, Thrasher, Adrian J, Ali, Robin R, Saurin, William, Kirsten, Romy, Schwarzwaelder, Kerstin, Schmidt, Manfred, Balaggan, Kamaljit S, Glimm, Hanno, Gaspar, H Bobby, Cesana, Daniela, Biasco, Luca, Aiuti, Alessandro, Howe, Steven J, Recchia, Alessandra, Gabriel, Richard, Cohen-Haguenauer, Odile, Wang, Wei, Mavilio, Fulvio, Yáñez-Muñoz, Rafael J, von Kalle, Christof, Ball, Claudia R

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Genome-wide high-throughput integrome analyses by nrLAM-PCR and next-generation sequencing von Schmidt, Manfred, Paruzynski, Anna, Arens, Anne, Gabriel, Richard, Bartholomae, Cynthia C, Scholz, Simone, Wang, Wei, Wolf, Stephan, Glimm, Hanno, von Kalle, Christof

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The balance between the intronic miR-342 and its host gene Evl determines hematopoietic cell fate decision von Herbst, Friederike, Lang, Tonio J L, Eckert, Elias S P, Wünsche, Peer, Wurm, Alexander A, Kindinger, Tim, Laaber, Karin, Hemmati, Shayda, Hotz-Wagenblatt, Agnes, Zavidij, Oksana, Paruzynski, Anna, Lu, Junyan, von Kalle, Christof, Zenz, Thorsten, Klein, Christoph, Schmidt, Manfred, Ball, Claudia R, Glimm, Hanno

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Retroviral Gene Therapy for X-linked Chronic Granulomatous Disease: Results From Phase I/II Trial von Kang, Hyoung Jin, Bartholomae, Cynthia C, Paruzynski, Anna, Arens, Anne, Kim, Sujeong, Yu, Seung Shin, Hong, Youngtae, Joo, Chang-Wan, Yoon, Nam-Kyung, Rhim, Jung-Woo, Kim, Joong Gon, Von Kalle, Christof, Schmidt, Manfred, Kim, Sunyoung, Ahn, Hyo Seop

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Mapping Active Gene-Regulatory Regions in Human Repopulating Long-Term HSCs von Wünsche, Peer, Eckert, Elias S.P., Holland-Letz, Tim, Paruzynski, Anna, Hotz-Wagenblatt, Agnes, Fronza, Raffaele, Rath, Tim, Gil-Farina, Irene, Schmidt, Manfred, von Kalle, Christof, Klein, Christoph, Ball, Claudia R., Herbst, Friederike, Glimm, Hanno

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Targeted resequencing for analysis of clonal composition of recurrent gene mutations in chronic lymphocytic leukaemia von Jethwa, Alexander, Hüllein, Jennifer, Stolz, Tatjana, Blume, Carolin, Sellner, Leopold, Jauch, Anna, Sill, Martin, Kater, Arnon P., te Raa, G. Doreen, Geisler, Christian, Oers, Marinus, Dietrich, Sascha, Dreger, Peter, Ho, Anthony D., Paruzynski, Anna, Schmidt, Manfred, Kalle, Christof, Glimm, Hanno, Zenz, Thorsten

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Cell Cycle Status of CD34+ Hemopoietic Stem Cells Determines Lentiviral Integration in Actively Transcribed and Development-related Genes von Papanikolaou, Eleni, Paruzynski, Anna, Kasampalidis, Ioannis, Deichmann, Annette, Stamateris, Evangelos, Schmidt, Manfred, von Kalle, Christof, Anagnou, Nicholas P

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Cell Cycle Status of CD34 super(+) Hemopoietic Stem Cells Determines Lentiviral Integration in Actively Transcribed and Development-related Genes von Papanikolaou, Eleni, Paruzynski, Anna, Kasampalidis, Ioannis, Deichmann, Annette, Stamateris, Evangelos, Schmidt, Manfred, von Kalle, Christof, Anagnou, Nicholas P

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Analysis of the Clonal Repertoire of Gene-Corrected Cells in Gene Therapy von Paruzynski, Anna, Glimm, Hanno, Schmidt, Manfred, von Kalle, Christof

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Lentiviral Vector Integration Profiles Differ in Rodent Postmitotic Tissues von Bartholomae, Cynthia C, Arens, Anne, Balaggan, Kamaljit S, Yáñez-Muñoz, Rafael J, Montini, Eugenio, Howe, Steven J, Paruzynski, Anna, Korn, Bernhard, Appelt, Jens Uwe, MacNeil, Angus, Cesana, Daniela, Abel, Ulrich, Glimm, Hanno, Naldini, Luigi, Ali, Robin R, Thrasher, Adrian J, von Kalle, Christof, Schmidt, Manfred

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C-8. Immunological and Metabolic Correction After Lentiviral Vector Gene Therapy for ADA Deficiency von Gaspar, Hubert B., Buckland, Karen, Carbonaro, Denise A., Shaw, Kit, Barman, Provobati, Davila, Alejandra, Gilmour, Kimberly C., Booth, Claire, Terrazs, Dayna, Cornetta, Kenneth, Paruzynski, Anna, Schmidt, Manfred, Sokolic, Robert, Candotti, Fabio, Thrasher, Adrian J., Kohn, Donald B.

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Abstract CT022: IVAC® MUTANOME - A first-in-human phase I clinical trial targeting individual mutant neoantigens for the treatment of melanoma von Miller, Matthias, Loquai, Carmen, Kloke, Björn-Philipp, Attig, Sebastian, Bidmon, Nicole, Bolte, Stefanie, Bukur, Valesca, Derhovanessian, Evelyna, Diekmann, Jan, Filbry, Angela, Heesch, Sandra, Hoeller, Christoph, Kuehlcke, Klaus, Langer, David, Loewer, Martin, Mueller, Felicitas, Ortseifer, Inga, Otte, Burkhard, Paruzynski, Anna, Rae, Richard, Schroers, Barbara, Seck, Christine, Spiess, Kristina, Tadmor, Arbel D., Vogler, Isabel, Vormehr, Mathias, Kemmer-Brueck, Alexandra, Kuhn, Andreas N., Luxemburger, Ulrich, Kreiter, Sebastian, Utikal, Jochen, Grabbe, Stephan, Tuereci, Oezlem, Sahin, Ugur

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