Myc-induced AMPK-phospho p53 pathway activates Bak to sensitize mitochondrial apoptosis von Nieminen, Anni I, Eskelinen, Vilja M, Haikala, Heidi M, Tervonen, Topi A, Yan, Yan, Partanen, Johanna I, Klefström, Juha

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Serine 62-Phosphorylated MYC Associates with Nuclear Lamins and Its Regulation by CIP2A Is Essential for Regenerative Proliferation von Myant, Kevin, Qiao, Xi, Halonen, Tuuli, Come, Christophe, Laine, Anni, Janghorban, Mahnaz, Partanen, Johanna I., Cassidy, John, Ogg, Erinn-Lee, Cammareri, Patrizia, Laiterä, Tiina, Okkeri, Juha, Klefström, Juha, Sears, Rosalie C., Sansom, Owen J., Westermarck, Jukka

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Breaking the epithelial polarity barrier in cancer: the strange case of LKB1/PAR-4 von Partanen, Johanna I., Tervonen, Topi A., Klefström, Juha

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Tumor suppressor function of Liver kinase B1 (Lkb1) is linked to regulation of epithelial integrity von Partanen, Johanna I., Tervonen, Topi A., Myllynen, Mikko, Lind, Essi, Imai, Misa, Katajisto, Pekka, Dijkgraaf, Gerrit J. P., Kovanen, Panu E., Mäkelä, Tomi P., Werb, Zena, Klefström, Juha

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Suppression of oncogenic properties of c-Myc by LKB1-controlled epithelial organization von Partanen, Johanna I, Nieminen, Anni I, Mäkelä, Tomi P, Klefstrom, Juha

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c-Myc Blazing a Trail of Death: Coupling of the Mitochondrial and Death Receptor Apoptosis Pathways by c-Myc von Nieminen, Anni I., Partanen, Johanna I., Klefstrom, Juha

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3D view to tumor suppression: lkb1, polarity and the arrest of oncogenic c-myc von Partanen, Johanna I., Nieminen, Anni I., Klefstrom, Juha

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Faulty Epithelial Polarity Genes and Cancer von Tervonen, Topi A., Partanen, Johanna I., Saarikoski, Sirkku T., Myllynen, Mikko, Marques, Elsa, Paasonen, Katriina, Moilanen, Anu, Wohlfahrt, Gerd, Kovanen, Panu E., Klefstrom, Juha

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c-Myc primed mitochondria determine cellular sensitivity to TRAIL-induced apoptosis von Nieminen, Anni I, Partanen, Johanna I, Hau, Annika, Klefstrom, Juha

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Chk1 Targeting Reactivates PP2A Tumor Suppressor Activity in Cancer Cells von KHANNA, Anchit, KAUKO, Otto, POKHAREL, Yuba R, PIMANDA, John, RUSSEL, Mike R, HAGLUND, Caj, COLE, Kristina A, KLEFSTRÖM, Juha, AITTOKALLIO, Tero, WEISS, Carsten, RISTIMÄKI, Ari, VISAKORPI, Tapio, BÖCKELMAN, Camilla, WESTERMARCK, Jukka, LAINE, Anni, SCHRECK, Ilona, PARTANEN, Johanna I, SZWAJDA, Agnieszka, BORMANN, Stefanie, BILGEN, Turker, HELENIUS, Merja

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Impact of epithelial organization on Myc expression and activity--letter von Partanen, Johanna I, Klefstrom, Juha

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Breaking the epithelial polarity barrier in cancer: the strange case of LKB1/PAR-4 von Partanen, Johanna I., Tervonen, Topi A., Klefström, Juha

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Myc-induced AMPK-phospho p53 pathway activates Bak to sensitize mitochondrial apoptosis von Nieminen, Anni I., Eskelinen, Vilja M., Haikala, Heidi M., Tervonen, Topi A., Yan, Yan, Partanen, Johanna I., Klefström, Juha

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Abstract PR03: Serine 62 phosphorylated MYC associates with nuclear lamins and its regulation by CIP2A is essential for proliferation induction in vivo von Myant, Kevin, Qiao, Xi, Halonen, Tuuli, Come, Christophe, Laine, Anni, Partanen, Johanna I., Ogg, Erinn-Lee, Laiterä, Tiina, Janghorban, Mahnaz, Okkeri, Juha, Klefström, Juha, Sears, Rosalie C., Sansom, Owen J., Westermarck, Jukka

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NTHL1 is a recessive cancer susceptibility gene von Nurmi, Anna K., Pelttari, Liisa M., Kiiski, Johanna I., Khan, Sofia, Nurmikolu, Mika, Suvanto, Maija, Aho, Niina, Tasmuth, Tiina, Kalso, Eija, Schleutker, Johanna, Kallioniemi, Anne, Heikkilä, Päivi, Aittomäki, Kristiina, Blomqvist, Carl, Nevanlinna, Heli

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Polygenic and clinical risk scores and their impact on age at onset and prediction of cardiometabolic diseases and common cancers von Mars, Nina, Koskela, Jukka T., Ripatti, Pietari, Kiiskinen, Tuomo T. J., Havulinna, Aki S., Lindbohm, Joni V., Ahola-Olli, Ari, Kurki, Mitja, Karjalainen, Juha, Palta, Priit, Neale, Benjamin M., Daly, Mark, Salomaa, Veikko, Palotie, Aarno, Widén, Elisabeth, Ripatti, Samuli

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Genome-wide meta-analysis conducted in three large biobanks expands the genetic landscape of lumbar disc herniations von Salo, Ville, Määttä, Juhani, Sliz, Eeva, Reimann, Ene, Mägi, Reedik, Reis, Kadri, Elhanas, Abdelrahman G., Reigo, Anu, Palta, Priit, Esko, Tõnu, Karppinen, Jaro, Kettunen, Johannes

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Evidence of a causal effect of genetic tendency to gain muscle mass on uterine leiomyomata von Sliz, Eeva, Tyrmi, Jaakko S., Rahmioglu, Nilufer, Zondervan, Krina T., Becker, Christian M., Uimari, Outi, Kettunen, Johannes

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Risk of Midlife Stroke After Adverse Pregnancy Outcomes: The FinnGen Study von Miller, Eliza C., Kauko, Anni, Tom, Sarah E., Laivuori, Hannele, Niiranen, Teemu, Bello, Natalie A.

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Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells von Bao, Erik L., Nandakumar, Satish K., Liao, Xiaotian, Bick, Alexander G., Karjalainen, Juha, Tabaka, Marcin, Gan, Olga I., Havulinna, Aki S., Kiiskinen, Tuomo T. J., Lareau, Caleb A., de Lapuente Portilla, Aitzkoa L., Li, Bo, Emdin, Connor, Codd, Veryan, Nelson, Christopher P., Walker, Christopher J., Churchhouse, Claire, de la Chapelle, Albert, Klein, Daryl E., Nilsson, Björn, Wilson, Peter W. F., Cho, Kelly, Pyarajan, Saiju, Gaziano, J. Michael, Samani, Nilesh J., Regev, Aviv, Palotie, Aarno, Neale, Benjamin M., Dick, John E., Natarajan, Pradeep, O’Donnell, Christopher J., Daly, Mark J., Milyavsky, Michael, Kathiresan, Sekar, Sankaran, Vijay G.

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